The Experts below are selected from a list of 114 Experts worldwide ranked by ideXlab platform
Wei Peng - One of the best experts on this subject based on the ideXlab platform.
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anti allergic rhinitis effects of caffeoylquinic acids from the fruits of xanthium strumarium in rodent animals via alleviating allergic and inflammatory reactions
Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy, 2019Co-Authors: Wei Peng, Ying Chen, Luyao Yu, Bingzhu YeAbstract:Abstract The fruits of Xanthium strumarium L., Asteraceae, have been used for various diseases in Chinese folk medicine, including allergic rhinitis, tympanitis, arthritis, ozena etc. The current study was aimed to investigate the therapeutic effects of caffeoylquinic acids from fruits of X. strumarium on allergic rhinitis in animals. The toxicity test indicated that the caffeoylquinic acids have no obvious toxicity. By using HPLC assays combined with reference standards, ten caffeoylquinic acids were identified as the predominant constituents. Anti-allergic activities of the caffeoylquinic acids were evaluated using passive cutaneous anaphylaxis test and Schultz-Dale test; dimethylbenzene induced ear edema test was performed to evaluate its anti-inflammatory effect. Then, the allergic rhinitis model in rats was established to evaluate the therapeutic effects of the caffeoylquinic acids against allergic rhinitis with the following indexes: allergic rhinitis symptom scores, serum levels of pro-inflammatory cytokines, histopathological examination, and histamine release. Our study revealed that the caffeoylquinic acids showed obvious anti-allergic and anti-inflammatory properties, and its treatments were beneficial for ameliorating the nasal symptoms, decreasing pro-inflammatory cytokines, and inhibiting the releases of histamine. Collectively, the caffeoylquinic acids might be utilized as effective and safe disease therapeutic agents for allergic rhinitis.
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Anti-allergic rhinitis effects of caffeoylquinic acids from the fruits of Xanthium strumarium in rodent animals via alleviating allergic and inflammatory reactions
Elsevier, 2019Co-Authors: Wei Peng, Ping Han, Ying Chen, Luping Qin, Hailiang Xin, Ting HanAbstract:The fruits of Xanthium strumarium L., Asteraceae, have been used for various diseases in Chinese folk medicine, including allergic rhinitis, tympanitis, arthritis, ozena etc. The current study was aimed to investigate the therapeutic effects of caffeoylquinic acids from fruits of X. strumarium on allergic rhinitis in animals. The toxicity test indicated that the caffeoylquinic acids have no obvious toxicity. By using HPLC assays combined with reference standards, ten caffeoylquinic acids were identified as the predominant constituents. Anti-allergic activities of the caffeoylquinic acids were evaluated using passive cutaneous anaphylaxis test and Schultz-Dale test; dimethylbenzene induced ear edema test was performed to evaluate its anti-inflammatory effect. Then, the allergic rhinitis model in rats was established to evaluate the therapeutic effects of the caffeoylquinic acids against allergic rhinitis with the following indexes: allergic rhinitis symptom scores, serum levels of pro-inflammatory cytokines, histopathological examination, and histamine release. Our study revealed that the caffeoylquinic acids showed obvious anti-allergic and anti-inflammatory properties, and its treatments were beneficial for ameliorating the nasal symptoms, decreasing pro-inflammatory cytokines, and inhibiting the releases of histamine. Collectively, the caffeoylquinic acids might be utilized as effective and safe disease therapeutic agents for allergic rhinitis. Keywords: Fructus Xanthii, Allergic rhinitis, Caffeoylquinic acids, Histopathology, Histamin
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anti allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of xanthium strumarium l in rodent animals
Phytomedicine, 2014Co-Authors: Wei Peng, Qianliang Ming, Qiaoyan Zhang, Yiping Jiang, Chengjian ZhengAbstract:Abstract The fruits of Xanthium strumarium L. (Asteraceae) have been used extensively in China for treatment of various diseases such as allergic rhinitis (AR), tympanitis, urticaria and arthritis or ozena. This study was designed to systemically investigate the effects of the caffeoylxanthiazonoside (CXT) isolated from fruits of X. strumarium on AR in rodent animals. Animals were orally administered with CXT. Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing tests were used to evaluate the analgesic effects of CXT; acetic acid-induced vascular permeability tests were performed to evaluate anti-inflammatory effect of CXT. Then, the model AR in rats was established to evaluate the effects of CXT on AR with the following tests: the sneezing and nasal scratching frequencies, IgE level in serum, and histopathological examinations. Our results demonstrated that CXT had favorable anti-allergic, anti-inflammatory and analgesic effects. Additionally, we found that CXT was helpful to ameliorate the nasal symptoms and to down-regulate IgE levels in AR rats. Thus, we suggested that CXT can be treated as a candidate for treating AR.
Chengjian Zheng - One of the best experts on this subject based on the ideXlab platform.
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anti allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of xanthium strumarium l in rodent animals
Phytomedicine, 2014Co-Authors: Wei Peng, Qianliang Ming, Qiaoyan Zhang, Yiping Jiang, Chengjian ZhengAbstract:Abstract The fruits of Xanthium strumarium L. (Asteraceae) have been used extensively in China for treatment of various diseases such as allergic rhinitis (AR), tympanitis, urticaria and arthritis or ozena. This study was designed to systemically investigate the effects of the caffeoylxanthiazonoside (CXT) isolated from fruits of X. strumarium on AR in rodent animals. Animals were orally administered with CXT. Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing tests were used to evaluate the analgesic effects of CXT; acetic acid-induced vascular permeability tests were performed to evaluate anti-inflammatory effect of CXT. Then, the model AR in rats was established to evaluate the effects of CXT on AR with the following tests: the sneezing and nasal scratching frequencies, IgE level in serum, and histopathological examinations. Our results demonstrated that CXT had favorable anti-allergic, anti-inflammatory and analgesic effects. Additionally, we found that CXT was helpful to ameliorate the nasal symptoms and to down-regulate IgE levels in AR rats. Thus, we suggested that CXT can be treated as a candidate for treating AR.
Yuan Jianyi - One of the best experts on this subject based on the ideXlab platform.
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research on development mechanism of highway Tympanites
Journal of Huangshi Institute of Technology, 2010Co-Authors: Yuan JianyiAbstract:Temperature diversity is an important factor for highway Tympanites to occur in permafrost region.According to macroshapes of Tympanites cracks,cracking mechanism of asphalt pavement is analyzed from principles of temperature cracks,which reflectes cracks and stress-strain relationship.Combined with climate and vehicle load,in-depth study is executed to investigate development machanism of highway Tympanites in seasonal frozen soil region.The results show that comprehensive effect of the basic physical characteristics of roadbed and external environment leads to highway Tympanites.
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numerical simulation analysis on temperature field for tianshan xinjiang highway Tympanites roadbed
Journal of East China Jiaotong University, 2007Co-Authors: Yuan JianyiAbstract:The diversity of temperature is an important factor for Tympanites to occur in highway roadbed.The physical model and calculating model of temperature field are founded according to the founded controlling equation in this paper. By simulating the changing progress of climate features,the temperature field of roadbed in permafrost region in different season is got.The variations of temperature field with time indicate the variations of freezing front-surface.Then,some results are got by analyzing the diversity of temperature of key points. The last,the technology assumption of effectively controlling Tympanites which combines replacing part frozen soil and resisting highway Tympanites structure is brought up.It has significant senses for further research of Tympanites' controlling technology.
Qianliang Ming - One of the best experts on this subject based on the ideXlab platform.
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anti allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of xanthium strumarium l in rodent animals
Phytomedicine, 2014Co-Authors: Wei Peng, Qianliang Ming, Qiaoyan Zhang, Yiping Jiang, Chengjian ZhengAbstract:Abstract The fruits of Xanthium strumarium L. (Asteraceae) have been used extensively in China for treatment of various diseases such as allergic rhinitis (AR), tympanitis, urticaria and arthritis or ozena. This study was designed to systemically investigate the effects of the caffeoylxanthiazonoside (CXT) isolated from fruits of X. strumarium on AR in rodent animals. Animals were orally administered with CXT. Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing tests were used to evaluate the analgesic effects of CXT; acetic acid-induced vascular permeability tests were performed to evaluate anti-inflammatory effect of CXT. Then, the model AR in rats was established to evaluate the effects of CXT on AR with the following tests: the sneezing and nasal scratching frequencies, IgE level in serum, and histopathological examinations. Our results demonstrated that CXT had favorable anti-allergic, anti-inflammatory and analgesic effects. Additionally, we found that CXT was helpful to ameliorate the nasal symptoms and to down-regulate IgE levels in AR rats. Thus, we suggested that CXT can be treated as a candidate for treating AR.
Qiaoyan Zhang - One of the best experts on this subject based on the ideXlab platform.
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anti allergic rhinitis effect of caffeoylxanthiazonoside isolated from fruits of xanthium strumarium l in rodent animals
Phytomedicine, 2014Co-Authors: Wei Peng, Qianliang Ming, Qiaoyan Zhang, Yiping Jiang, Chengjian ZhengAbstract:Abstract The fruits of Xanthium strumarium L. (Asteraceae) have been used extensively in China for treatment of various diseases such as allergic rhinitis (AR), tympanitis, urticaria and arthritis or ozena. This study was designed to systemically investigate the effects of the caffeoylxanthiazonoside (CXT) isolated from fruits of X. strumarium on AR in rodent animals. Animals were orally administered with CXT. Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing tests were used to evaluate the analgesic effects of CXT; acetic acid-induced vascular permeability tests were performed to evaluate anti-inflammatory effect of CXT. Then, the model AR in rats was established to evaluate the effects of CXT on AR with the following tests: the sneezing and nasal scratching frequencies, IgE level in serum, and histopathological examinations. Our results demonstrated that CXT had favorable anti-allergic, anti-inflammatory and analgesic effects. Additionally, we found that CXT was helpful to ameliorate the nasal symptoms and to down-regulate IgE levels in AR rats. Thus, we suggested that CXT can be treated as a candidate for treating AR.
