The Experts below are selected from a list of 39330 Experts worldwide ranked by ideXlab platform
D Thirumalai - One of the best experts on this subject based on the ideXlab platform.
-
on the origin of the Unusual Behavior in the stretching of single stranded dna
Journal of Chemical Physics, 2012Co-Authors: Ngo Minh Toan, D ThirumalaiAbstract:Force-extension curves (FECs), which quantify the response of a variety of biomolecules subject to mechanical force (f), are often quantitatively fit using worm-like chain (WLC) or freely jointed chain (FJC) models. These models predict that the chain extension, x, normalized by the contour length increases linearly at small f and at high forces scale as x ∼ (1 − f−α), where α = 0.5 for WLC and unity for FJC. In contrast, experiments on single-stranded DNA (ssDNA) show that over a range of f and ionic concentration, x scales as x ∼ ln f, which cannot be explained using WLC or FJC models. Using theory and simulations we show that this Unusual Behavior in FEC in ssDNA is due to sequence-independent polyelectrolyte effects. We show that the x ∼ ln f arises because in the absence of force the tangent correlation function, quantifying chain persistence, decays algebraically on length scales on the order of the Debye length. Our theory, which is most appropriate for monovalent salts, quantitatively fits the experimental data and further predicts that such a regime is not discernible in double-stranded DNA.
-
on the origin of the Unusual Behavior in the stretching of single stranded dna
arXiv: Soft Condensed Matter, 2012Co-Authors: Ngo Minh Toan, D ThirumalaiAbstract:Force extension curves (FECs), which quantify the response of a variety of biomolecules subject to mechanical force ($f$), are often quantitatively fit using worm-like chain (WLC) or freely-jointed chain (FJC) models. These models predict that the chain extension, $x$, normalized by the contour length increases linearly at small $f$ and at high forces scale as $x \sim (1 - f^{-\alpha})$ where $\alpha$= 0.5 for WLC and unity for FJC. In contrast, experiments on ssDNA show that over a range of $f$ and ionic concentration, $x$ scales as $x\sim\ln f$, which cannot be explained using WLC or FJC models. Using theory and simulations we show that this Unusual Behavior in FEC in ssDNA is due to sequence-independent polyelectrolyte effects. We show that the $x\sim \ln f$ arises because in the absence of force the tangent correlation function, quantifying chain persistence, decays algebraically on length scales on the order of the Debye length. Our theory, which is most appropriate for monovalent salts, quantitatively fits the experimental data and further predicts that such a regime is not discernible in double stranded DNA.
Ngo Minh Toan - One of the best experts on this subject based on the ideXlab platform.
-
on the origin of the Unusual Behavior in the stretching of single stranded dna
Journal of Chemical Physics, 2012Co-Authors: Ngo Minh Toan, D ThirumalaiAbstract:Force-extension curves (FECs), which quantify the response of a variety of biomolecules subject to mechanical force (f), are often quantitatively fit using worm-like chain (WLC) or freely jointed chain (FJC) models. These models predict that the chain extension, x, normalized by the contour length increases linearly at small f and at high forces scale as x ∼ (1 − f−α), where α = 0.5 for WLC and unity for FJC. In contrast, experiments on single-stranded DNA (ssDNA) show that over a range of f and ionic concentration, x scales as x ∼ ln f, which cannot be explained using WLC or FJC models. Using theory and simulations we show that this Unusual Behavior in FEC in ssDNA is due to sequence-independent polyelectrolyte effects. We show that the x ∼ ln f arises because in the absence of force the tangent correlation function, quantifying chain persistence, decays algebraically on length scales on the order of the Debye length. Our theory, which is most appropriate for monovalent salts, quantitatively fits the experimental data and further predicts that such a regime is not discernible in double-stranded DNA.
-
on the origin of the Unusual Behavior in the stretching of single stranded dna
arXiv: Soft Condensed Matter, 2012Co-Authors: Ngo Minh Toan, D ThirumalaiAbstract:Force extension curves (FECs), which quantify the response of a variety of biomolecules subject to mechanical force ($f$), are often quantitatively fit using worm-like chain (WLC) or freely-jointed chain (FJC) models. These models predict that the chain extension, $x$, normalized by the contour length increases linearly at small $f$ and at high forces scale as $x \sim (1 - f^{-\alpha})$ where $\alpha$= 0.5 for WLC and unity for FJC. In contrast, experiments on ssDNA show that over a range of $f$ and ionic concentration, $x$ scales as $x\sim\ln f$, which cannot be explained using WLC or FJC models. Using theory and simulations we show that this Unusual Behavior in FEC in ssDNA is due to sequence-independent polyelectrolyte effects. We show that the $x\sim \ln f$ arises because in the absence of force the tangent correlation function, quantifying chain persistence, decays algebraically on length scales on the order of the Debye length. Our theory, which is most appropriate for monovalent salts, quantitatively fits the experimental data and further predicts that such a regime is not discernible in double stranded DNA.
O Chauvet - One of the best experts on this subject based on the ideXlab platform.
-
transport properties of pmma carbon nanotubes composites
Synthetic Metals, 2001Co-Authors: Jm Benoit, Benoit Corraze, S Lefrant, Werner J Blau, P Bernier, O ChauvetAbstract:We report transport measurements on PMMA-singlewalled carbon nanotubes composites films. The films are characterized by Raman spectroscopy, optical absorption and electron microscopy. At room temperature, classical percolation theory applies. It shows that the composites resistivity is indeed controlled by the nanotubes. Decreasing the temperature shows a Unusual Behavior which suggests that a distribution of intertube/interbundle barriers of some 10 of Kelvin is superposed to the topological percolation problem.
Qazi Naveed Ahmed - One of the best experts on this subject based on the ideXlab platform.
-
2 oxo driven unconventional reactions microwave assisted approaches to tetrahydrofuro 3 2 d oxazoles and furanones
Organic Letters, 2015Co-Authors: Narsaiah Battini, Satyanarayana Battula, Raju Ranjith Kumar, Qazi Naveed AhmedAbstract:A highly efficient, novel, microwave-assisted, metal-free, diastereoselective synthesis of tetrahydrofuro[3,2-d]oxazole is disclosed. The synthesis of napthoxazoles is achieved for the first time without the aid of an external catalyst. On the contrary, our reactions generated naphthofuranones when treated in the presence of metals in microwave/thermal conditions. The Unusual Behavior of our reactions has further been explored in the generation of furanones from tetrahydrofuro[3,2-d]oxazole through the use of metals.
Frédéric Kaplan - One of the best experts on this subject based on the ideXlab platform.
-
Robotic clicker training
Robotics and Autonomous Systems, 2002Co-Authors: Frédéric Kaplan, Pierre Yves Oudeyer, Eniko Kubinyi, Adam MiklosiAbstract:Abstract In this paper, we want to propose the idea that some techniques used for animal training might be helpful for solving human–robot interaction problems in the context of entertainment robotics. We present a model for teaching complex actions to an animal-like autonomous robot based on “clicker training”, a method used efficiently by professional trainers for animals of different species. After describing our implementation of clicker training on an enhanced version of AIBO, Sony’s four-legged robot, we argue that this new method can be a promising technique for teaching Unusual Behavior and sequences of actions to a pet robot.
-
Robotic clicker training (draft)
2002Co-Authors: Frédéric Kaplan, Pierre Yves OudeyerAbstract:In this paper we want to propose the idea that some techniques used for animal training might be helpful for solving human robot interaction problems in the context of entertainment robotics. We present a model for teaching complex actions to an animal-like autonomous robot based on ”clicker training”, a method used efficiently by professional trainers for animals of different species. After describing our implementation of clicker training on an enhanced version of AIBO, Sony’s four-legged robot, we argue that this new method can be a promising technique for teaching Unusual Behavior and sequences of actions to a pet robot.
-
Taming robots with clicker training A solution for teaching complex Behaviors
2001Co-Authors: Frédéric KaplanAbstract:In this paper we want to propose the idea that some techniques used for animal training might be helpful for solving human robot interaction problems in the context of entertainment robotics. We present a model for teaching complex actions to an animallike autonomous robot based on ”clicker training”, a method used efficiently by professional trainers for animals of different species. After describing our implementation of clicker training on an enhanced version of AIBO, Sony’s four-legged robot, we argue that this new method can be a promising technique for teaching Unusual Behavior and sequences of actions