The Experts below are selected from a list of 474 Experts worldwide ranked by ideXlab platform
J. Peter Rubin - One of the best experts on this subject based on the ideXlab platform.
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A Prospective, Randomized, Multicenter Trial Assessing a Novel Lysine-Derived Urethane Adhesive in a Large Flap Surgical Procedure without Drains
Aesthetic Plastic Surgery, 2015Co-Authors: Joseph P. Hunstad, Joseph Michaels, A. Jay Burns, Sheri Slezak, W. Grant Stevens, Dottie M. Clower, J. Peter RubinAbstract:Objective To evaluate the safety and effectiveness of a lysine-derived Urethane Adhesive as a noninvasive alternative to closed suction drains in a commonly performed large flap surgical procedure. Methods One hundred thirty subjects undergoing abdominoplasty at five centers were prospectively randomized to standard flap closure with surgical drains (Control group) or a lysine-derived Urethane Adhesive (Treatment group) without drains. The primary outcome measured was the number of post-operative procedures, including drain removals (as the event marking the use of a surgical drain) and needle aspirations. Secondary endpoints included total wound drainage, cumulative days of treatment, and days to drain removal. A patient questionnaire evaluating quality of life measures was also administered. Results Subjects in the Treatment group required significantly fewer post-operative procedures compared to the Control group (1.8 ± 3.8 vs. 2.4 ± 1.2 procedures; p
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A Prospective, Randomized, Multicenter Trial Assessing a Novel Lysine-Derived Urethane Adhesive in a Large Flap Surgical Procedure without Drains
Aesthetic plastic surgery, 2015Co-Authors: Joseph P. Hunstad, Joseph Michaels, A. Jay Burns, Sheri Slezak, W. Grant Stevens, Dottie M. Clower, J. Peter RubinAbstract:Objective To evaluate the safety and effectiveness of a lysine-derived Urethane Adhesive as a noninvasive alternative to closed suction drains in a commonly performed large flap surgical procedure.
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Randomized, Prospective Study of TissuGlu® Surgical Adhesive in the Management of Wound Drainage Following Abdominoplasty
Aesthetic Plastic Surgery, 2012Co-Authors: Klaus J. Walgenbach, Holger Bannasch, Stefan Kalthoff, J. Peter RubinAbstract:Background Wound drainage and seroma formation following abdominoplasty remain significant concerns to both surgeons and patients due to the resulting increased need for patient follow-up and delays in returning to normal function. While a number of approaches are used to reduce wound drainage and seroma formation, there is still no definitive solution. A promising strategy to reduce these complications is the development of an effective method for closing dead space between tissue layers in order to achieve improved patient outcomes. Methods We conducted a multicenter, prospective, randomized trial assessing the use of a lysine-derived Urethane Adhesive (TissuGlu®, Cohera Medical) in patients undergoing abdominoplasty. Twenty patients were randomized to a treatment group and a control group, with the Adhesive applied to the abdominal wall prior to closure of the abdominoplasty flap in the treatment group. Control patients underwent an identical procedure but without application of TissuGlu. Outcome measures included time to drain removal, total wound drainage prior to drain removal, and surgical complications. Results The use of TissuGlu was associated with a trend toward decreased time to drain removal compared to the control group (2.9 ± 1.4 vs. 3.7 ± 1.5 days; P = 0.13). Mean total drain volume also tended to be lower in the treatment versus the control group (208.7 ± 138.2 vs. 303.5 ± 240.8 ml; P = 0.14). There were no differences in adverse events or complication rates between the two study groups. Conclusion The application of TissuGlu in abdominoplasty is safe and may decrease wound drainage and the length of time required for postsurgical drains in abdominoplasty patients.
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Lysine-derived Urethane surgical Adhesive prevents seroma formation in a canine abdominoplasty model.
Plastic and reconstructive surgery, 2008Co-Authors: Thomas W. Gilbert, Dottie M. Clower, Stephen F. Badylak, Jeffrey A. Gusenoff, Eric J. Beckman, Patrick Daly, J. Peter RubinAbstract:BACKGROUND Seroma formation is a common postoperative complication following many surgical procedures, including abdominoplasty. Several approaches have been investigated to prevent seroma formation by draining fluid or attempting to eliminate dead space, but these approaches have limited effectiveness. METHODS A canine model of abdominoplasty was developed that reliably produced seroma formation. Bilateral subcutaneous pockets were created in the ventrolateral abdominal wall and additional tissue damage was inflicted using electrocautery. On one side, the tissue layers were treated with a lysine-derived Urethane Adhesive before closure, whereas the control side received no treatment before standard closure of the incision. RESULTS Seroma formation (60 +/- 45 ml) was observed on the control side, whereas the treated side had adherence between the tissue layers and minimal if any fluid accumulation (1.7 +/- 1.4 ml) (p < 0.01) (n = 7). The Adhesive invoked little or no cellular response, based on histologic examination of the tissue. CONCLUSION The Urethane surgical Adhesive was effective in preventing the formation of seroma in this canine abdominoplasty model.
Craig S. Dyson - One of the best experts on this subject based on the ideXlab platform.
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Piezoelectric tactile integrated circuit sensor
Journal of Vacuum Science & Technology A: Vacuum Surfaces and Films, 1995Co-Authors: Edward S. Kolesar, Craig S. DysonAbstract:A two‐dimensional, electrically multiplexed tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8×8 matrix. Each electrode occupies a 400×400‐μm square area, and they are separated from each other by 300 μm. A 40‐μm‐thick piezoelectric PVDF polymer film was attached to the electrode array with a nonconductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8–135 grams of force (gf). The time required to electrically interrogate, measure, and record the response of the sensor’s set of 64 taxels is less than 50 ms, the hysteresis level is tolerable, and, for operation in the sensor’s linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitations associated with piezoelectric‐based tactile sensors have been resolved by implementing a precharge voltage...
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Robotic Tactile Sensors Fabricated from a Monolithic Silicon Integrated Circuit and a Piezoelectric Polyvinylidene Fluoride Thin Film
1991Co-Authors: Craig S. DysonAbstract:Abstract : The purpose of this research effort was to design, fabricate, and test a tactile sensor system consisting of an external high impedance switch circuit, an external multiplexing circuit, and a tactile sensor IC. In order to accomplish this objective, a hardware design and selection process was implemented along with a logical test methodology. An external multiplexer circuit samples all of the array elements in 50 ms. The current prototype sensor has linearity spanning loads of 0.8 g to 135 g, a load resolution of 20 g, and a maximum bandwidth of 25 Hz. Using an elementary shape recognition algorithm the sensor can recognize the shape of a contact load with a spatial resolution on the order of 700 micron. A comparison of three different Adhesives used to bond the piezoelectric PVDF film to the surface of the electrode array was made and a Urethane Adhesive was selected for its superior electrical and physical properties.
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Object imaging with a piezoelectric robotic tactile sensor
Proceedings of the IEEE 1993 National Aerospace and Electronics Conference-NAECON 1993, 1Co-Authors: Craig S. Dyson, N.c. Yauilla, Edward S. KolesarAbstract:A two-dimensional, electrically-multiplexed robotic tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8*8 matrix. Each electrode occupies a 400*400 mu m square area, and they are separated from each other by 300 mu m. A 40- mu m thick piezoelectric PVDF polymer film was attached to the electrode array with an electrically non-conductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8 to 135 grams of force (gmf). The response bandwidth is 25 Hz, the hysteresis level is tolerable, and, for operation in the sensor's linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitation associated with piezoelectric-based tactile sensors has been solved by implementing a novel pre-charge voltage bias technique to initialize the pre- and post-load sensor responses. A rudimentary tactile object image measurement procedure for applied loads has been devised to recognize the silhouette of a sharp edge, square, trapezoid, isosceles triangle, circle, toroid, slotted screw, and cross-slotted screw. >
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Tactile integrated circuit sensor realized with a piezoelectric polymer
1996 Proceedings. Eighth Annual IEEE International Conference on Innovative Systems in Silicon, 1Co-Authors: Edward S. Kolesar, Craig S. Dyson, R.r. Reston, R.c. Fitch, D.g. Ford, S.d. NelmsAbstract:A two-dimensional, electrically-multiplexed tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8/spl times/8 matrix. Each electrode occupies a 400/spl times/400 /spl mu/m square area, and they are separated from each other by 300 /spl mu/m. A 40-/spl mu/m thick piezoelectric PVDF polymer film was attached to the electrode array with a non-conductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8 to 135 grams-of-force (gmf) (0.008-1.35 Newtons (N)). The time required to electrically interrogate, measure, and record the response of the sensor's set of 64 taxels is less than 50 ms, the hysteresis level is tolerable, and, for operation in the sensor's linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitations associated with piezoelectric-based tactile sensors have been resolved by implementing a pre-charge voltage bias technique to establish known pre- and post-load sensor responses. A rudimentary tactile object image measurement procedure has been devised to recognize the silhouette of a sharp edge, square, trapezoid, isosceles triangle, circle, toroid, slotted screw, and cross-slotted screw.
Edward S. Kolesar - One of the best experts on this subject based on the ideXlab platform.
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Piezoelectric tactile integrated circuit sensor
Journal of Vacuum Science & Technology A: Vacuum Surfaces and Films, 1995Co-Authors: Edward S. Kolesar, Craig S. DysonAbstract:A two‐dimensional, electrically multiplexed tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8×8 matrix. Each electrode occupies a 400×400‐μm square area, and they are separated from each other by 300 μm. A 40‐μm‐thick piezoelectric PVDF polymer film was attached to the electrode array with a nonconductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8–135 grams of force (gf). The time required to electrically interrogate, measure, and record the response of the sensor’s set of 64 taxels is less than 50 ms, the hysteresis level is tolerable, and, for operation in the sensor’s linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitations associated with piezoelectric‐based tactile sensors have been resolved by implementing a precharge voltage...
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Object imaging with a piezoelectric robotic tactile sensor
Proceedings of the IEEE 1993 National Aerospace and Electronics Conference-NAECON 1993, 1Co-Authors: Craig S. Dyson, N.c. Yauilla, Edward S. KolesarAbstract:A two-dimensional, electrically-multiplexed robotic tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8*8 matrix. Each electrode occupies a 400*400 mu m square area, and they are separated from each other by 300 mu m. A 40- mu m thick piezoelectric PVDF polymer film was attached to the electrode array with an electrically non-conductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8 to 135 grams of force (gmf). The response bandwidth is 25 Hz, the hysteresis level is tolerable, and, for operation in the sensor's linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitation associated with piezoelectric-based tactile sensors has been solved by implementing a novel pre-charge voltage bias technique to initialize the pre- and post-load sensor responses. A rudimentary tactile object image measurement procedure for applied loads has been devised to recognize the silhouette of a sharp edge, square, trapezoid, isosceles triangle, circle, toroid, slotted screw, and cross-slotted screw. >
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Tactile integrated circuit sensor realized with a piezoelectric polymer
1996 Proceedings. Eighth Annual IEEE International Conference on Innovative Systems in Silicon, 1Co-Authors: Edward S. Kolesar, Craig S. Dyson, R.r. Reston, R.c. Fitch, D.g. Ford, S.d. NelmsAbstract:A two-dimensional, electrically-multiplexed tactile sensor was realized by coupling a piezoelectric polyvinylidene fluoride (PVDF) polymer film to a monolithic silicon integrated circuit (IC). The IC incorporates 64 sensor electrodes arranged in a symmetrical 8/spl times/8 matrix. Each electrode occupies a 400/spl times/400 /spl mu/m square area, and they are separated from each other by 300 /spl mu/m. A 40-/spl mu/m thick piezoelectric PVDF polymer film was attached to the electrode array with a non-conductive Urethane Adhesive. The response of the tactile sensor is linear for loads spanning 0.8 to 135 grams-of-force (gmf) (0.008-1.35 Newtons (N)). The time required to electrically interrogate, measure, and record the response of the sensor's set of 64 taxels is less than 50 ms, the hysteresis level is tolerable, and, for operation in the sensor's linear range, taxel crosstalk is negligible. The historically persistent stability and response reproducibility limitations associated with piezoelectric-based tactile sensors have been resolved by implementing a pre-charge voltage bias technique to establish known pre- and post-load sensor responses. A rudimentary tactile object image measurement procedure has been devised to recognize the silhouette of a sharp edge, square, trapezoid, isosceles triangle, circle, toroid, slotted screw, and cross-slotted screw.
Dottie M. Clower - One of the best experts on this subject based on the ideXlab platform.
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A Prospective, Randomized, Multicenter Trial Assessing a Novel Lysine-Derived Urethane Adhesive in a Large Flap Surgical Procedure without Drains
Aesthetic Plastic Surgery, 2015Co-Authors: Joseph P. Hunstad, Joseph Michaels, A. Jay Burns, Sheri Slezak, W. Grant Stevens, Dottie M. Clower, J. Peter RubinAbstract:Objective To evaluate the safety and effectiveness of a lysine-derived Urethane Adhesive as a noninvasive alternative to closed suction drains in a commonly performed large flap surgical procedure. Methods One hundred thirty subjects undergoing abdominoplasty at five centers were prospectively randomized to standard flap closure with surgical drains (Control group) or a lysine-derived Urethane Adhesive (Treatment group) without drains. The primary outcome measured was the number of post-operative procedures, including drain removals (as the event marking the use of a surgical drain) and needle aspirations. Secondary endpoints included total wound drainage, cumulative days of treatment, and days to drain removal. A patient questionnaire evaluating quality of life measures was also administered. Results Subjects in the Treatment group required significantly fewer post-operative procedures compared to the Control group (1.8 ± 3.8 vs. 2.4 ± 1.2 procedures; p
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A Prospective, Randomized, Multicenter Trial Assessing a Novel Lysine-Derived Urethane Adhesive in a Large Flap Surgical Procedure without Drains
Aesthetic plastic surgery, 2015Co-Authors: Joseph P. Hunstad, Joseph Michaels, A. Jay Burns, Sheri Slezak, W. Grant Stevens, Dottie M. Clower, J. Peter RubinAbstract:Objective To evaluate the safety and effectiveness of a lysine-derived Urethane Adhesive as a noninvasive alternative to closed suction drains in a commonly performed large flap surgical procedure.
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Lysine-derived Urethane surgical Adhesive prevents seroma formation in a canine abdominoplasty model.
Plastic and reconstructive surgery, 2008Co-Authors: Thomas W. Gilbert, Dottie M. Clower, Stephen F. Badylak, Jeffrey A. Gusenoff, Eric J. Beckman, Patrick Daly, J. Peter RubinAbstract:BACKGROUND Seroma formation is a common postoperative complication following many surgical procedures, including abdominoplasty. Several approaches have been investigated to prevent seroma formation by draining fluid or attempting to eliminate dead space, but these approaches have limited effectiveness. METHODS A canine model of abdominoplasty was developed that reliably produced seroma formation. Bilateral subcutaneous pockets were created in the ventrolateral abdominal wall and additional tissue damage was inflicted using electrocautery. On one side, the tissue layers were treated with a lysine-derived Urethane Adhesive before closure, whereas the control side received no treatment before standard closure of the incision. RESULTS Seroma formation (60 +/- 45 ml) was observed on the control side, whereas the treated side had adherence between the tissue layers and minimal if any fluid accumulation (1.7 +/- 1.4 ml) (p < 0.01) (n = 7). The Adhesive invoked little or no cellular response, based on histologic examination of the tissue. CONCLUSION The Urethane surgical Adhesive was effective in preventing the formation of seroma in this canine abdominoplasty model.
John G. Dillard - One of the best experts on this subject based on the ideXlab platform.
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Surface characterization of synthetic vulcanized rubber treated with oxygen plasma
Surface and Interface Analysis, 1998Co-Authors: M. Mercedes Pastor-blas, José Miguel Martín-martínez, John G. DillardAbstract:The surface of a synthetic vulcanized styrene-butadiene rubber (R2) was treated in an oxygen plasma to improve adhesion in joints prepared with a one-component solvent-based polyester-Urethane Adhesive. The modifications produced on the rubber surface by plasma treatment were assessed using advancing and receding contact angle measurements, x-ray photoelectron spectroscopy, (XPS), infrared-attenuated total reflection spectroscopy and scanning electron microscopy. Adhesion was obtained from T-peel tests of treated R2 rubber/polyUrethane Adhesive joints. Several experimental variables were considered, such as the radio-frequency power and the length and lifetime of the plasma treatment. The treatment in the oxygen plasma produced a noticeable decrease in contact angle, which can be mainly ascribed to the creation of C-O and C=O moieties on the rubber surface. Advancing and receding contact angles only differed by ∼10°. Depending on the experimental conditions used, some ablation was produced on the surface, which was more noticeable as the length and power of the treatment increased. An adequate performance of Adhesive joints was obtained using a power of 50 W and a time for oxygen plasma treatment of
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Surface Analysis of Debonded Chlorinated Vulcanized Styrene-Butadiene Rubber Joints
The Journal of Adhesion, 1997Co-Authors: M. Mercedes Pastor-blas, José Miguel Martín-martínez, John G. DillardAbstract:Abstract A synthetic vulcanized styrene-butadiene rubber (R) was treated with a halogenation agent (TCI = trichloroisocyanuric acid) to produce improved adhesion (i.e. high T-peel strength) in joints prepared with a one-component, solvent-based polyester Urethane Adhesive. Several amounts (0.5 to 7 wt%) of TCI solutions in ethyl acetate were applied to the rubber surface and, after T-peel tests were carried out, the surfaces of the debonded chlorinated rubber pieces were analyzed with XPS, ATR-infra-red (ATR-IR) spectroscopy, Scanning Electron Microscopy (SEM) coupled with EDX analysis, and contact angle measurements. The T-peel strength of unchlorinated rubber (0 wt% TCl) joints was small due to the migration of low molecular species (mainly microcrystalline wax) to the rubber surface during the cure of the Adhesive, creating a weak layer in which the failure was produced. Chlorination with amounts of TCI up to 2 wt% produced a noticeable increase in T-peel strength, but treatment with higher amounts of ...
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The Effect of Surface Preparation and Exposure Environment on the Bond Failure Processes in Adhesively Bonded Sheet Molded Composite (SMC)
The Journal of Adhesion, 1995Co-Authors: J. C. Wells, B. T. Thompson, John G. DillardAbstract:Abstract The durability of Adhesively-bonded composites has been investigated using a wedge-type specimen. Polyester-resin, fiberglass sheet molded composite (SMC) was bonded with a commercial two-part poly-Urethane Adhesive. The SMC composite received one of four different surface preparations: no treatment, abrasion, priming, or abrasion and priming. The wedge test was used to study the durability of the samples which were exposed to air and to the vapor above water, concentrated ammonium hydroxide, or methanol at 60[ddot]C. The crack length was measured during the experiments. The crack growth rate as a function of surface treatment varied in the manner: untreated ≈ abraded > primed ≈ abraded and primed. The crack growth rate as a function of vapor changed in the manner: methanol > ammonium hydroxide > water ≈ air. The samples were removed at the conclusion of the test and the failure mode was determined visually, by scanning electron microscopy (SEM), and by X-ray photoelectron spectros-copy (XPS). In...
