The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
P. Kiilholma - One of the best experts on this subject based on the ideXlab platform.
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Lower Urinary Tract Symptoms in Patients with Sjögren’s Syndrome and Systemic Lupus Erythematosus
International Urogynecology Journal, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
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Lower Urinary tract symptoms in patients with Sjögren's syndrome and systemic lupus erythematosus.
International urogynecology journal and pelvic floor dysfunction, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjogren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
M. Haarala - One of the best experts on this subject based on the ideXlab platform.
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Lower Urinary Tract Symptoms in Patients with Sjögren’s Syndrome and Systemic Lupus Erythematosus
International Urogynecology Journal, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
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Lower Urinary tract symptoms in patients with Sjögren's syndrome and systemic lupus erythematosus.
International urogynecology journal and pelvic floor dysfunction, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjogren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
A. Alanen - One of the best experts on this subject based on the ideXlab platform.
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Lower Urinary Tract Symptoms in Patients with Sjögren’s Syndrome and Systemic Lupus Erythematosus
International Urogynecology Journal, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
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Lower Urinary tract symptoms in patients with Sjögren's syndrome and systemic lupus erythematosus.
International urogynecology journal and pelvic floor dysfunction, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjogren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
M. Hietarinta - One of the best experts on this subject based on the ideXlab platform.
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Lower Urinary Tract Symptoms in Patients with Sjögren’s Syndrome and Systemic Lupus Erythematosus
International Urogynecology Journal, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
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Lower Urinary tract symptoms in patients with Sjögren's syndrome and systemic lupus erythematosus.
International urogynecology journal and pelvic floor dysfunction, 2000Co-Authors: M. Haarala, A. Alanen, M. Hietarinta, P. KiilholmaAbstract:Sjogren’s syndrome (SS) and systemic lupus erythematosus (SLE) are autoimmune Diseases which have many similarities with interstitial cystitis (IC), a Urinary Bladder Disease with unknown etiology. This survey on the occurrence, severity and nature of lower Urinary tract symptoms among patients suffering from SS or SLE showed that these patients have significantly more Urinary complaints, especially irritative Bladder symptoms, than age- and sex-matched controls. We studied 36 patients with SS, 85 patients with SLE and 121 controls. In these groups, 25%, 29% and 66%, respectively, were free of Urinary symptoms. The prevalences of mild symptoms were 61%, 62% and 27%, and severe symptoms 14%, 9% and 7% in the respective groups. SS and SLE patients with Urinary complaints reported mostly Urinary frequency (27% and 62%) and suprapubic pain (36% and 34%). The most common symptom in the control group was stress Urinary incontinence. The frequency of lower Urinary tract problems in patients with SS and SLE supports the concept that autoimmune disorders also have Bladder affections.
William G. Newman - One of the best experts on this subject based on the ideXlab platform.
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Genetics of human congenital Urinary Bladder Disease
Pediatric Nephrology, 2014Co-Authors: Adrian S. Woolf, Helen M. Stuart, William G. NewmanAbstract:Lower Urinary tract and/or kidney malformations are collectively the most common cause of end-stage renal Disease in children, and they are also likely to account for a major subset of young adults requiring renal replacement therapy. Advances have been made regarding the discovery of the genetic causes of human kidney malformations. Indeed, testing for mutations of key nephrogenesis genes is now feasible for patients seen in nephrology clinics. Unfortunately, less is known about defined genetic bases of human lower Urinary tract anomalies. The focus of this review is the genetic bases of congenital structural and functional disorders of the Urinary Bladder. Three are highlighted. First, prune belly syndrome, where mutations of CHRM3 , encoding an acetylcholine receptor, HNF1B , encoding a transcription factor, and ACTA2 , encoding a cytoskeletal protein, have been reported. Second, the urofacial syndrome, where mutations of LRIG2 and HPSE2 , encoding proteins localised in nerves invading the fetal Bladder, have been defined. Finally, we review emerging evidence that Bladder exstrophy may have genetic bases, including variants in the TP63 promoter. These genetic discoveries provide a new perspective on a group of otherwise poorly understood Diseases.
