Uterine Cervix Dysplasia

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Richard M. Niles - One of the best experts on this subject based on the ideXlab platform.

  • Vitamin A and cancer.
    Nutrition, 2000
    Co-Authors: Richard M. Niles
    Abstract:

    11. Giuliano AR, Papenfuss M, Nour M, et al. Antioxidant nutrients: associationswith persistent human papillomavirus infection. Cancer Epidemiol Biomark Prev1997;8:91712. Potischman N, Brinton LA. Nutrition and cervical Dysplasia. Cancer CausesControl 1996;7:11313. Basu J, Palan PR, Vermund SH, et al. Plasma ascorbic acid and b-carotene levelsin women evaluated for HPV infection, smoking, and cervical Dysplasia. CancerDet Prev 1991;15:16714. Potischman N, Herrero R, Brinton LA, et al. A case-control study of nutrientstatus and invasive cervical cancer. Am J Epidemiol 1991;134:134715. Potischman N, Hoover R, Brinton LA, et al. The relations between cervicalcancer and serological markers of nutritional status. Nutr Cancer 1994;21:19316. Van Eenwyk J, Davis F, Bowen P. Dietary and serum carotenoids and cervicalintraepithelial neoplasia. Int J Cancer 1991;48:3417. Palan P, Mikhail M, Goldberg G, et al. Plasma levels if b-carotene, lycopene,canthaxanthin, retinol, a-tocopherol in cervical intraepithelial neoplasia andcancer. Clin Cancer Res 1996;2:18118. Batieha AM, Armenian HK, Morris JS, Spate VE, Comstock GW. Serummicronutrients and the subsequent risk of cervical cancer in a population basednested case-control study. Cancer Epidemiol Biomark Prev 1993;2:33519. Clinton SK, Emenhiser C, Schwartz SJ, et al. Cis-trans lycopene isomers,carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomark Prev1996;5:82320. Mangels AR, Holden JM, Beecher GR, Froman M, Lanza E. Carotenoid contentof fruits and vegetables: an evaluation of analytic data. J Am Diet Assoc1993;93:28421. Brock K, Berry G, Mock P, et al. Nutrients in diet and plasma and risk of in situcervical cancer. J Natl Cancer Inst 1988;80:58022. Palan P, Mikhail M, Basu J, Romney S. Plasma levels of antioxidant b-caroteneand a-tocopherol in Uterine Cervix Dysplasia and cancer. Nutr Cancer 1991;15:1323. Knekt P. Serum vitamin E level and risk of female cancers. Int J Epidemiol1988;17:28124. Cuzick J, de Stvola B, Russel M, Thomas B. Vitamin A, vitamin E, and the riskof cervical intraepithelial neoplasia. Br J Cancer 1990;62:65125. Kwasniewska A, Tukendorf A, Semczuk M. Content of a-tocopehrol in bloodserum of human papillomavirus-infected women with cervical Dysplasias. NutrCancer 1997;28:24826. Giuliano AR, Gapstur S. Can cervical Dysplasia and cancer be prevented withnutrients? Nut Rev 1998;56:927. Palmer HJ, Paulson KE. Reactive oxygen species and antioxidants in signaltransduction and gene expression. Nutr Rev 1997;55:35328. Beck MA, Shi Q, Morris VC, Levander OA. Rapid genomic evolution of anon-virulent Coxsackievirus B3 in selenium-deficient mice results in selection ofidentical virulent isolates. Nat Med 1995;1:43329. Peterhans E. Oxidants and antioxidants in viral diseases: disease mechanisms andmetabolic regulation. J Nutr 1997;127:962S30. Hennet T, Perhans E, Stocker R. Alterations in antioxidant defenses in lung andliver of mice infected with influenza-A virus. J Gen Virol 1992;73:3931. Oda T, Akaike T, Hamamoto T, et al. Oxygen radicals in influenza-inducedpathogenesis and treatment with pyran polymer-conjugated SOD. Science 1989;244:97432. Pace GW, Leaf CD. The role of oxidative stress in HIV disease. Free Rad BiolMed 1995;19:52333. Packer L, Suzuki YJ. Vitamin E and alpha-lipoate: role in antioxidant recyclingand activation of the NF-kB transcription factor. Mol Aspects Med 1993;14:22934. Cripe TP, Alderborn A, Anderson RD, et al. Transcriptional activation of thehuman papillomavirus-16 P97 promoter by an 88-nucleotide enhancer containingdistinct cell-dependent and AP-1 responsive modules. New Biol 1990;2:45035. Offord EA, Beard P. A member of the activator protein 1 family found inkeratinocytes but not in fibroblasts required for transcription from a humanpapillomavirus type 18 promoter. J Virol 1990;64:479236. Rosl F, Das BC, Lengert M, Geletneky K, zur Hausen H. Antioxidant-inducedchanges of the AP-1 transcription complex are paralleled by a selective suppres-sion of human papillomavirus transcription. J Virol 1997;71:362

T. Pisarski - One of the best experts on this subject based on the ideXlab platform.

  • CO2 laser in treatment of Uterine Cervix Dysplasia in women with infertility
    Ginekologia polska, 1994
    Co-Authors: Tomasz Opala, J. Wozniak, M Pisarska-krawczyk, Maciej Wilczak, E Guglas, T. Pisarski
    Abstract:

    The authors presented use of carbon dioxide laser in treatment of Dysplasia of the Uterine Cervix in women with malreproduction. Between November 1991 and September 1993 in the Department of Reproduction, Institute of Gynecology and Obstetrics, Academy of Medicine, Poznan the CO2-laser vaporisation in 21 women was done. In 19 patients the healing was achieved. In two of 21 women in control examination CIN was diagnosed. They were treated with electroconisation. In control examination no signs of Dysplasia in all women were observed. The patients are still under control in our department.

Yamaguchi M - One of the best experts on this subject based on the ideXlab platform.

  • Clinical studies on intravaginal administration of CDDP for Dysplasia, carcinoma in situ and microinvasive carcinoma of the Uterine Cervix
    Nihon Sanka Fujinka Gakkai zasshi, 1992
    Co-Authors: Nakayama K, Sano Y, Endo Y, Sato H, Ohyama T, Yamaguchi M
    Abstract:

    We attempted CDDP (cis-diaminedichloroplatinum) intravaginal administration by directly exposing the Uterine Cervix to CDDP in cases of Dysplasia of the Uterine Cervix and cervical intraepithelial and micro-invasive carcinoma. Out of 12 patients, 7 had Dysplasia of the Uterine Cervix (Dysplasia was mild in 4, of an intermediate level in 1, 4 with mild Dysplasia, 1 with and advanced in 2); 3 had carcinoma in situ, and 2 had microinvasive carcinoma. For CDDP intravaginal administration, a gauze tampon containing CDDP (5mg) was inserted into the vagina. CDDP administration was repeated daily for 10 days. The total dosage of CDDP administered was 50mg (new paragraph). During this period, vaginal cytologic examination was conducted and total plasma Pt content was determined daily for all. Following the completion of CDDP administration, the Uterine cervices of those with Dysplasia were histologically examined. For those with carcinoma in situ and microinvasive carcinoma, simple total hysterectomy was performed after intravaginal administration of CDDP to determine its therapeutic efficacy and the Pt concentration of the tissue; 1. In the 7 cases of Dysplasia, dysplastic cell degeneration was observed 1-2 days after the start of intravaginal CDDP administration and these cells disappeared in all cases after its completion. 2. Sixteen histological sections of the resected cervical specimens from the 3 cases of carcinoma in situ showed complete disappearance of cancerous cells. 3. In the 2 cases of microinvasive carcinoma, no tumor cells were detected in one case; in the other case, tumor cells persisted in part of the resected specimen.(ABSTRACT TRUNCATED AT 250 WORDS)

Mirosław Wielgoś - One of the best experts on this subject based on the ideXlab platform.

  • Is routine performance of the Uterine Cervix canal curettage prior to the curettage of the Uterine cavity justified
    Ginekologia polska, 2017
    Co-Authors: Szymon Piątek, Jacek Lipa, Monika Górska, Katarzyna Malecha, Grzegorz Panek, Mirosław Wielgoś
    Abstract:

    Objectives: Endocervical curettage (ECC) together with the dilatation and curettage of the Uterine cavity (D & C) is routinely performed in everyday clinical practice. The aim of this study is to assess the rationale of the performance of ECC prior to D & C in indications other than abnormal Uterine bleeding (AUB). Material and methods: Case histories of 736 patients after ECC performed in the 1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, were analyzed retrospectively, the indications for the procedure — age, menopausal status, parity, procedure operator’s experience — as well as the result of the histopathology examination were taken into account. Three groups of patients were distinguished based on the indications for the procedure. Results: In 645 (87.6%) of cases normal histopathology results were obtained. 40 (5.4%) cases were abnormal. 31 cases of Uterine Cervix Dysplasia were disclosed (CIN 1–20; CIN 2–5; CIN 3–6), 8 cases of endometrial cancer and 1 case of cancer of the Uterine Cervix were disclosed. In 51 (7%) of cases tissue material for histopathology examination was not obtained. In patients where ECC and D & C were performed due to indications other than abnormal bleeding from Uterine cavity, no abnormal results were revealed. In addition, in this group the highest number of non-diagnostic ECCs was reported (11.59%; p < 0.05). Conclusions: In the case of endometrial biopsy for indications other than AUB routine ECC prior to D & C need not be performed.

Tomasz Opala - One of the best experts on this subject based on the ideXlab platform.

  • CO2 laser in treatment of Uterine Cervix Dysplasia in women with infertility
    Ginekologia polska, 1994
    Co-Authors: Tomasz Opala, J. Wozniak, M Pisarska-krawczyk, Maciej Wilczak, E Guglas, T. Pisarski
    Abstract:

    The authors presented use of carbon dioxide laser in treatment of Dysplasia of the Uterine Cervix in women with malreproduction. Between November 1991 and September 1993 in the Department of Reproduction, Institute of Gynecology and Obstetrics, Academy of Medicine, Poznan the CO2-laser vaporisation in 21 women was done. In 19 patients the healing was achieved. In two of 21 women in control examination CIN was diagnosed. They were treated with electroconisation. In control examination no signs of Dysplasia in all women were observed. The patients are still under control in our department.