The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
Lucianne Cople Maia - One of the best experts on this subject based on the ideXlab platform.
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Effect of TiF_4 Varnish on microbiological changes and caries prevention: in situ and in vivo models
Clinical Oral Investigations, 2019Co-Authors: Adílis Kalina Alexandria, Camila Nassur, Carolina Bezerra Cavalcanti Nóbrega, Luciana Salles Branco-de-almeida, Katia Regina Netto Santos, Alexandre Rezende Vieira, Aline Almeida Neves, Pedro Luiz Rosalen, Ana Maria Gondim Valença, Lucianne Cople MaiaAbstract:Objective The aim of this study was to evaluate microbiological changes, oral soft tissue toxicity, and caries-preventive effect of an experimental titanium tetrafluoride (TiF_4) Varnish compared with a commercially available fluoride Varnish (NaF), using in situ and in vivo models. Materials and methods The treatment groups were the following: TiF_4 Varnish (experimental Varnish), Duraphat® (fluoride positive control), placebo Varnish (no fluoride), and no treatment (negative control). The Varnishes were applied once over the enamel surface using a microbrush. For the in vivo study, 48 Wistar rats were infected with Streptococcus sobrinus 6715, received a treatment, and were submitted to a cariogenic challenge. After 4 weeks, S. sobrinus , oral soft tissue toxicity, presence, and severity of caries were evaluated. For the in situ study, 12 volunteers took part in this randomized crossover, double-blind study performed in four phases of 14 days each. They used intraoral appliances containing four enamel specimens that received the Varnish according treatment group. After 24 h, the Varnish was removed and plaque accumulation was allowed. A 20% sucrose solution was dripped over the enamel blocks (10×/day for 5 min each). Total streptococci, S. mutans , Lactobacillus , Candida spp. counts, and presence of white spot lesions were evaluated. Lesion depth was also quantified by micro-CT. Results For the in vivo study, the fluoride (F-Varnishes) showed a statistically significant reduction in the percentage of S. sobrinus compared to the negative control ( p
Stuart A Gansky - One of the best experts on this subject based on the ideXlab platform.
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fluoride Varnish efficacy in preventing early childhood caries
Journal of Dental Research, 2006Co-Authors: Jane A Weintraub, Francisco Ramosgomez, Sara G Shain, C I Hoover, John D B Featherstone, Stuart A GanskyAbstract:To determine the efficacy of fluoride Varnish (5% NaF, Duraphat®, Colgate) added to caregiver counseling to prevent early childhood caries, we conducted a two-year randomized, dental-examiner-masked clinical trial. Initially, 376 caries-free children, from low-income Chinese or Hispanic San Francisco families, were enrolled (mean age ± standard deviation, 1.8 ± 0.6 yrs). All families received counseling, and children were randomized to the following groups: no fluoride Varnish, fluoride Varnish once/year, or fluoride Varnish twice/year. An unexpected protocol deviation resulted in some children receiving less active fluoride Varnish than assigned. Intent-to-treat analyses showed a fluoride Varnish protective effect in caries incidence, p < 0.01. Analyzing the number of actual, active fluoride Varnish applications received resulted in a dose-response effect, p < 0.01. Caries incidence was higher for ‘counseling only’ vs. ‘counseling + fluoride Varnish assigned once/year’ (OR = 2.20, 95% CI 1.19–4.08) and ‘...
Adílis Kalina Alexandria - One of the best experts on this subject based on the ideXlab platform.
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Effect of TiF_4 Varnish on microbiological changes and caries prevention: in situ and in vivo models
Clinical Oral Investigations, 2019Co-Authors: Adílis Kalina Alexandria, Camila Nassur, Carolina Bezerra Cavalcanti Nóbrega, Luciana Salles Branco-de-almeida, Katia Regina Netto Santos, Alexandre Rezende Vieira, Aline Almeida Neves, Pedro Luiz Rosalen, Ana Maria Gondim Valença, Lucianne Cople MaiaAbstract:Objective The aim of this study was to evaluate microbiological changes, oral soft tissue toxicity, and caries-preventive effect of an experimental titanium tetrafluoride (TiF_4) Varnish compared with a commercially available fluoride Varnish (NaF), using in situ and in vivo models. Materials and methods The treatment groups were the following: TiF_4 Varnish (experimental Varnish), Duraphat® (fluoride positive control), placebo Varnish (no fluoride), and no treatment (negative control). The Varnishes were applied once over the enamel surface using a microbrush. For the in vivo study, 48 Wistar rats were infected with Streptococcus sobrinus 6715, received a treatment, and were submitted to a cariogenic challenge. After 4 weeks, S. sobrinus , oral soft tissue toxicity, presence, and severity of caries were evaluated. For the in situ study, 12 volunteers took part in this randomized crossover, double-blind study performed in four phases of 14 days each. They used intraoral appliances containing four enamel specimens that received the Varnish according treatment group. After 24 h, the Varnish was removed and plaque accumulation was allowed. A 20% sucrose solution was dripped over the enamel blocks (10×/day for 5 min each). Total streptococci, S. mutans , Lactobacillus , Candida spp. counts, and presence of white spot lesions were evaluated. Lesion depth was also quantified by micro-CT. Results For the in vivo study, the fluoride (F-Varnishes) showed a statistically significant reduction in the percentage of S. sobrinus compared to the negative control ( p
Frank Courts - One of the best experts on this subject based on the ideXlab platform.
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assessing the effect of fluoride Varnish on early enamel carious lesions in the primary dentition
Journal of the American Dental Association, 2001Co-Authors: Jaana T Autiogold, Frank CourtsAbstract:ABSTRACT Background The aim of this study was to evaluate the effect of fluoride Varnish on enamel caries progression in the primary dentition. Methods One hundred forty-two children in Head Start schools (3 to 5 years old) were randomized into the Varnish and control groups. Children in the Varnish group received fluoride Varnish (Duraphat, Colgate-Palmolive Co.) at baseline and after four months, and children in the control group received no professional fluoride applications. Two calibrated examiners performed the examinations at baseline and at nine months. Results At nine months, the authors found that in the control group, 37.8 percent of active enamel lesions on occlusal, buccal and lingual surfaces became inactive, 3.6 percent progressed and 36.9 percent did not change. In the Varnish group, 81.2 percent became inactive, 2.4 percent progressed and 8.2 percent did not change. The difference between the groups was statistically significant ( P P E mfs, values; decayed with initial enamel lesions, missing and filled teeth, or d E mft, values; and decayed surfaces with initial enamel lesions, or d E s, values were significantly lower in the Varnish group after nine months than they were at baseline ( P Conclusions These results suggest that fluoride Varnish applications may be an effective measure in reversing active pit-and-fissure enamel lesions in the primary dentition. Clinical Implications Fluoride Varnishes are safe, easy to apply and well-accepted by patients. This study shows that fluoride Varnish may offer an efficient, non-surgical alternative for the treatment of decay in children.
Jane A Weintraub - One of the best experts on this subject based on the ideXlab platform.
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fluoride Varnish efficacy in preventing early childhood caries
Journal of Dental Research, 2006Co-Authors: Jane A Weintraub, Francisco Ramosgomez, Sara G Shain, C I Hoover, John D B Featherstone, Stuart A GanskyAbstract:To determine the efficacy of fluoride Varnish (5% NaF, Duraphat®, Colgate) added to caregiver counseling to prevent early childhood caries, we conducted a two-year randomized, dental-examiner-masked clinical trial. Initially, 376 caries-free children, from low-income Chinese or Hispanic San Francisco families, were enrolled (mean age ± standard deviation, 1.8 ± 0.6 yrs). All families received counseling, and children were randomized to the following groups: no fluoride Varnish, fluoride Varnish once/year, or fluoride Varnish twice/year. An unexpected protocol deviation resulted in some children receiving less active fluoride Varnish than assigned. Intent-to-treat analyses showed a fluoride Varnish protective effect in caries incidence, p < 0.01. Analyzing the number of actual, active fluoride Varnish applications received resulted in a dose-response effect, p < 0.01. Caries incidence was higher for ‘counseling only’ vs. ‘counseling + fluoride Varnish assigned once/year’ (OR = 2.20, 95% CI 1.19–4.08) and ‘...
