The Experts below are selected from a list of 153 Experts worldwide ranked by ideXlab platform
H.p.j. Buschman - One of the best experts on this subject based on the ideXlab platform.
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vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels
Epilepsy Research, 2010Co-Authors: J J Ardesch, H.p.j. Buschman, J R Sikken, Petrus H Veltink, H E Van Der Aa, G HagemanAbstract:Purpose Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Methods Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. Results The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. Conclusions VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness.
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Vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels.
Epilepsy research, 2010Co-Authors: J J Ardesch, J R Sikken, Petrus H Veltink, H E Van Der Aa, G Hageman, H.p.j. BuschmanAbstract:Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness. Copyright 2010 Elsevier B.V. All rights reserved.
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Laryngeal and vocal changes during vagus nerve stimulation in epileptic patients.
Journal of voice : official journal of the Voice Foundation, 2002Co-Authors: Willem Kersing, P.h. Dejonckere, Hans E. Van Der Aa, H.p.j. BuschmanAbstract:Abstract Left vagus nerve stimulation (VNS) by means of an implanted electrode has proven to reduce seizure frequency in epileptic patients with medically refractory seizures. This technique is now widely applied over the world. Voice changes appear to be one of the major side effects. The morphodynamic changes in the larynx and the acoustic impacts have been analyzed in detail in 7 implanted patients. Basic vagus stimulation is well tolerated. Extra stimulation induces an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold. The result, when the patient phonates, consists of a slight increase of F 0 as well as a moderate increase of random period perturbation, but there is no evidence for the occurrence of "bifurcations." Further, as the glottic closure remains sufficient, there is no increase in turbulent noise. The lack of increase in turbulent noise and the lack of "bifurcations" appears to clearly differentiate a spasmodic contraction of the vocal cord from a unilateral vocal Fold paralysis.
J J Ardesch - One of the best experts on this subject based on the ideXlab platform.
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vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels
Epilepsy Research, 2010Co-Authors: J J Ardesch, H.p.j. Buschman, J R Sikken, Petrus H Veltink, H E Van Der Aa, G HagemanAbstract:Purpose Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Methods Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. Results The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. Conclusions VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness.
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Vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels.
Epilepsy research, 2010Co-Authors: J J Ardesch, J R Sikken, Petrus H Veltink, H E Van Der Aa, G Hageman, H.p.j. BuschmanAbstract:Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness. Copyright 2010 Elsevier B.V. All rights reserved.
J R Sikken - One of the best experts on this subject based on the ideXlab platform.
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vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels
Epilepsy Research, 2010Co-Authors: J J Ardesch, H.p.j. Buschman, J R Sikken, Petrus H Veltink, H E Van Der Aa, G HagemanAbstract:Purpose Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Methods Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. Results The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. Conclusions VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness.
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Vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels.
Epilepsy research, 2010Co-Authors: J J Ardesch, J R Sikken, Petrus H Veltink, H E Van Der Aa, G Hageman, H.p.j. BuschmanAbstract:Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness. Copyright 2010 Elsevier B.V. All rights reserved.
Petrus H Veltink - One of the best experts on this subject based on the ideXlab platform.
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vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels
Epilepsy Research, 2010Co-Authors: J J Ardesch, H.p.j. Buschman, J R Sikken, Petrus H Veltink, H E Van Der Aa, G HagemanAbstract:Purpose Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Methods Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. Results The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. Conclusions VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness.
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Vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels.
Epilepsy research, 2010Co-Authors: J J Ardesch, J R Sikken, Petrus H Veltink, H E Van Der Aa, G Hageman, H.p.j. BuschmanAbstract:Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness. Copyright 2010 Elsevier B.V. All rights reserved.
H E Van Der Aa - One of the best experts on this subject based on the ideXlab platform.
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vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels
Epilepsy Research, 2010Co-Authors: J J Ardesch, H.p.j. Buschman, J R Sikken, Petrus H Veltink, H E Van Der Aa, G HagemanAbstract:Purpose Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Methods Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. Results The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. Conclusions VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness.
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Vagus nerve stimulation for epilepsy activates the vocal Folds maximally at therapeutic levels.
Epilepsy research, 2010Co-Authors: J J Ardesch, J R Sikken, Petrus H Veltink, H E Van Der Aa, G Hageman, H.p.j. BuschmanAbstract:Vagus nerve stimulation (VNS) for medically refractory epilepsy can give hoarseness due to stimulation of the recurrent laryngeal nerve. For a group of VNS-therapy users this side-effect interferes severely with their daily activities. Our goal was to investigate the severity of intra-operative VNS-related vocal Fold contraction at different pulse widths and current output parameters. We investigated electromyographic and morphometric alterations on the vocal Folds during VNS. Vocal Fold EMG experiments were conducted intra-operatively during the implantation of a VNS system. During surgery the VNS pulse generator was programmed to stimulate at different pulse durations. At each pulse width the EMG-threshold current was determined by electrical stimulation of the vagus nerve with increasing stimulation currents. Laryngostroboscopic examination was performed after surgery to analyze the effects of spontaneous stimulation on the larynx. The vocal Fold EMG and morphodynamic changes in the larynx have been analyzed in eight patients. In all patients left vocal Fold EMG-threshold was between 0.25 and 0.50 mA. Pulse duration had little influence on the EMG-threshold level. Vocal Fold EMG saturation levels were reached between 0.75 and 1.00 mA. Video stroboscopic monitoring showed that stimulation induced an adductory spasm of either the ipsilateral vocal Fold or the Vestibular Fold, and was present remarkably irrespective of the presence of hoarseness. VNS causes pronounced effects on the vocal Folds even at low stimulation amplitudes. At therapeutic levels even at the lowest stimulation pulse durations, the vocal Fold contract, however, this does not necessarily give hoarseness. Copyright 2010 Elsevier B.V. All rights reserved.
