The Experts below are selected from a list of 213 Experts worldwide ranked by ideXlab platform
Yukifumi Nawa - One of the best experts on this subject based on the ideXlab platform.
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a case of ascaris suum Visceral Larva Migrans diagnosed by using a suum Larval excretory secretory es antigen
Scandinavian Journal of Infectious Diseases, 2006Co-Authors: Fukumi Nakamurauchiyama, Nobuaki Akao, Yoshifumi Tokunaga, Asahi Suzuki, Kenji Hiromatsu, Shigemi Hitomi, Yukifumi NawaAbstract:A 42-y-old female presented with common cold-like symptoms. Laboratory data showed mild liver dysfunction together with peripheral blood eosinophilia. She was suspected of having a helminthic infection, however parasite eggs or Larvae were not detected by repeated stool examinations. Eventually she transpired to have a high IgG antibody titer against excretory-secretary (ES) antigen of Ascaris suum Larvae, but not of Toxocara canis Larvae, suggesting that she had been suffering from Visceral Larva Migrans (VLM) caused by A. suum. Her sickness improved without any treatment. Current results clearly highlight the usefulness of ES antigens derived from Larvae of A. suum for the fine discrimination of VLM caused by A. suum and by T. canis. Application of A. suum derived ES antigens as a diagnostic tool may reveal the distinctive clinical features of VLM caused by A. suum.
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myocarditis associated with Visceral Larva Migrans due to toxocara canis
Internal Medicine, 2002Co-Authors: Hiroaki Shimokawa, Yukifumi Nawa, Toru Kubota, Akira TakeshitaAbstract:A 26-year-old man who was diagnosed with myocarditis presented eosinopilia after having eaten raw meat several times before the admission. Since the antibody titer against Toxocara canis was high, we diagnosed that he had Visceral Larva Migrans due to Toxocara canis associated with myocarditis and eosinophilia. He was then treated with oral albendazole and prednisolone for 4 weeks and eosinophil count and hepatic enzymes were normalized along with the decrease in the antibody titer. We consider that his myocarditis was probably caused by direct Larval migration and/or by hypersensitivity reaction, for which combined therapy with albendazole and prednisolone was effective. (Internal Medicine 41: 706-708, 2002)
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chronic eosinophilic pneumonia due to Visceral Larva Migrans
Internal Medicine, 2002Co-Authors: Koji Inoue, Yoshikazu Inoue, Toru Arai, Yukifumi Nawa, Yozo Kashiwa, Satora Yamamoto, Mitsunori SakataniAbstract:A 38-year-old woman presented with worsening cough, blood eosinophilia, and pulmonary infiltrates. Bronchoalveolar lavage showed 96.4% eosinophils. The diagnosis of Visceral Larva Migrans (VLM) was made based on the positive results in enzyme-linked immunosorbent assay for Toxocara canis together with clinical symptoms and laboratory data. Pulmonary infiltrates due to VLM generally manifest as a transient form of Loffler's syndrome or simple eosinophilic pneumonia mainly in children. Here we report an adult case of VLM, with pulmonary infiltrates pathologically proven to be eosinophilic pneumonia, which persisted for 7 weeks before anthelmintic treatment with albendazole and manifested as chronic eosinophilic pneumonia.(Internal Medicine 41: 478-482, 2002)
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localised myelitis caused by Visceral Larva Migrans due to ascaris suum masquerading as an isolated spinal cord tumour
Journal of Neurology Neurosurgery and Psychiatry, 2001Co-Authors: Manabu Osoegawa, Shunro Matsumoto, Kenji Ishiwata, Hirofumi Ochi, Kenji Yamasaki, Izumi Horiuchi, Y O Kira, Fukumi Nakamurauchiyama, Yukifumi NawaAbstract:Eosinophilic meningitis is caused by various parasites, a representive of which is Angiostrongylus cantonensis . The disease has also occasionally been reported in Visceral Larva Migrans due to Toxocara canis , although the parenchymatous involvement of the CNS is extremely rare in T canis Visceral Larva Migrans.1 Recently an outbreak of Visceral Larva Migrans due to Ascaris suum infection has been reported in Kyushu, Japan, where chemical fertiliser has been replaced in part with pig manure.2 We report a case of myelopathy probably due to A suum infection. A 22 year old man, living in the Tokyo metropolitan area, noticed that his right hand was swollen and warm in mid-August, 1999. The oedema subsided spontaneously within a week. In early October, he felt thermanaesthesia in his right leg while he was taking a shower. Because he had sometimes felt numbness in one or both axillas from the beginning of November, he was admitted to a hospital on 7 December 1999. Physical examination on admission showed hypalgesia and thermanaesthesia below the Th9 level on the right and a positive Lhermitte's sign. Peripheral blood eosinophil count was raised at 610/μl (10.5% leucocytes). Serum IgE concentration was 155 IU/ml (normal <240 IU/ml). Thoracic …
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hepatic imaging studies on patients with Visceral Larva Migrans due to probable ascaris suum infection
Abdominal Imaging, 1999Co-Authors: Katsuhiro Hayashi, Yukifumi Nawa, H Tahara, Kiyoshi Yamashita, Kazuo Kuroki, Ryuji Matsushita, Shojiro Yamamoto, Takeshi Hori, Shuichi Hirono, Hirohito TsubouchiAbstract:Visceral Larva Migrans (VLM) is a disease usually observed in children in which the Larvae of animal parasites invade and reside in human tissues for long periods. Although the common causal species of VLM are Toxocara canis and T. cati, we identified three adult patients with VLM, probably due to Ascaris suum, whose diagnosis was made by specific immunoserological tests. The patients complained of respiratory symptoms, and laboratory tests showed pronounced eosinophilia, but neither Larvae nor eggs were detected in stool samples. We present the findings of various imaging studies of the patients. Multiple small hypoechoic mass lesions were demonstrated by ultrasound tomography, which disappeared after anti-helminthic therapy. Hepatic mass lesions were detected as low-density areas on computed tomography, as high signal intensities on T2-weighted magnetic resonance images, as space-occupying regions in liver scintigraphy, and as yellow-white nodules in laparoscopy. Although biopsied liver tissue specimens showed marked infiltrations of eosinophiles in the portal tracts and hepatic sinusoids, neither Larvae nor eggs could be identified.
Hong Sik Byun - One of the best experts on this subject based on the ideXlab platform.
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mri findings of spinal Visceral Larva Migrans of toxocara canis
European Journal of Radiology, 2010Co-Authors: Dae Kun Oh, Pyoung Jeon, Hong Sik ByunAbstract:Abstract Purpose The purpose of this study is to investigate the MRI findings of Visceral Larva Migrans (VLS) of Toxocara canis in spinal cord. Materials and methods We retrospectively reviewed spinal MRI findings in eight patients with serologically proven Toxocara canis between 2005 and 2008. We evaluated the location, length, extent and migration of the lesion, MR signal intensity (SI), enhancement pattern, and swelling of the spinal cord. We evaluated clinical features including presenting symptoms and signs and treatment response. Results Total 8 patients (M = 8; age range 36–79 years) were included. The lesions were located in the cervical or thoracic spinal cord in all patients. All lesions showed high SI and minimal or mild swelling of involved spinal cord on T2WI and focal nodular enhancement on posterior or posterolateral segment of spinal cord. The length of involved lesion was relatively short in most patients. There was a migration of lesion in one patient. In spite of albendazole or steroid treatment, neurological symptoms or signs were not significantly improved in all patients. Conclusion Although all lesions show non-specific imaging findings like non-tumorous myelopathy mimicking transverse myelitis, single lesion, focal nodular enhancement on posterior or posterolateral segment of spinal cord, relatively short segmental involvement and migration of lesion may be characteristic findings of spinal VLM of Toxocara canis. In addition, the reluctant response to the treatment may be characteristic of spinal VLM of Toxocara canis.
Ryuichi Okubo - One of the best experts on this subject based on the ideXlab platform.
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mri studies of spinal Visceral Larva Migrans syndrome
Journal of the Neurological Sciences, 2006Co-Authors: Fujio Umehara, Hideki Ookatsu, Daisuke Hayashi, Akifumi Uchida, Yukari Douchi, Hisashi Kawabata, Rina Goto, Akihiro Hashiguchi, Eiji Matsuura, Ryuichi OkuboAbstract:We report serial MR findings in four patients with myelitis caused by Visceral Larva Migrans syndrome due to Toxocara canis or Ascaris suum infection. MR imaging revealed spinal cord swelling with or without gadolinium enhancement in three patients. T2-weighted images showed high signal intensities preferentially located in both lateral and posterior columns. Antihelmintic and corticosteroid treatment yielded improvement in neurologic deficits and spinal lesions. However, one patient with T. canis infection relapsed associated with reappearance of MRI abnormalities.
Shunro Matsumoto - One of the best experts on this subject based on the ideXlab platform.
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pulmonary ct findings of Visceral Larva Migrans due to ascaris suum
European Respiratory Journal, 2012Co-Authors: Koichi Honda, Fumito Okada, Yumiko Ando, Shunro Matsumoto, Hiromu MoriAbstract:Poster: "ESTI 2012 / E-0038 / Pulmonary CT Findings of Visceral Larva Migrans due to Ascaris suum" by: "K. Honda, F. Okada, Y. Ando, A. Ono, S. Matsumoto, H. Mori; Oita/JP"
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pulmonary computed tomography findings of Visceral Larva Migrans caused by ascaris suum
Journal of Computer Assisted Tomography, 2007Co-Authors: Fumito Okada, Yumiko Ando, Shunro Matsumoto, Shinji Yotsumoto, Shuichi Tanoue, Masaki Wakisaka, Hiromu MoriAbstract:Objective: To retrospectively evaluate the computed tomography (CT) findings of pulmonary involvement in patients with Visceral Larva Migrans caused by Ascaris suum. Methods: Institutional review board approval was obtained, and informed consent was waived. Chest CT scans obtained between January 1994 and November 2005 in 32 patients infected with A. suum were retrospectively evaluated by 3 chest radiologists. In 4 patients who underwent surgical or transbronchial biopsy, comparisons of the CT images with the actual specimens were performed. Results: On CT scans, abnormal findings were seen in 28 patients. The most common abnormality consisted of nodules (n = 19) in which the majority had a halo of ground-glass attenuation (n = 17), followed by ground-glass attenuation (n = 18), and interlobular septal thickening (n = 14). These abnormalities were predominantly seen in the peripheral lung (n = 25). Of the 7 patients who underwent follow-up CT scans, nodules (n = 6) and ground-glass attenuation (n = 5) had migrated in 4 patients. Pathologically, these findings corresponded to marked eosinophilic infiltration into the interstitium. Conclusions: These CT findings are considered to be suggestive of thoracic involvement in patients with Visceral Larva Migrans caused by A. suum.
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localised myelitis caused by Visceral Larva Migrans due to ascaris suum masquerading as an isolated spinal cord tumour
Journal of Neurology Neurosurgery and Psychiatry, 2001Co-Authors: Manabu Osoegawa, Shunro Matsumoto, Kenji Ishiwata, Hirofumi Ochi, Kenji Yamasaki, Izumi Horiuchi, Y O Kira, Fukumi Nakamurauchiyama, Yukifumi NawaAbstract:Eosinophilic meningitis is caused by various parasites, a representive of which is Angiostrongylus cantonensis . The disease has also occasionally been reported in Visceral Larva Migrans due to Toxocara canis , although the parenchymatous involvement of the CNS is extremely rare in T canis Visceral Larva Migrans.1 Recently an outbreak of Visceral Larva Migrans due to Ascaris suum infection has been reported in Kyushu, Japan, where chemical fertiliser has been replaced in part with pig manure.2 We report a case of myelopathy probably due to A suum infection. A 22 year old man, living in the Tokyo metropolitan area, noticed that his right hand was swollen and warm in mid-August, 1999. The oedema subsided spontaneously within a week. In early October, he felt thermanaesthesia in his right leg while he was taking a shower. Because he had sometimes felt numbness in one or both axillas from the beginning of November, he was admitted to a hospital on 7 December 1999. Physical examination on admission showed hypalgesia and thermanaesthesia below the Th9 level on the right and a positive Lhermitte's sign. Peripheral blood eosinophil count was raised at 610/μl (10.5% leucocytes). Serum IgE concentration was 155 IU/ml (normal <240 IU/ml). Thoracic …
Hiromu Mori - One of the best experts on this subject based on the ideXlab platform.
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pulmonary ct findings of Visceral Larva Migrans due to ascaris suum
European Respiratory Journal, 2012Co-Authors: Koichi Honda, Fumito Okada, Yumiko Ando, Shunro Matsumoto, Hiromu MoriAbstract:Poster: "ESTI 2012 / E-0038 / Pulmonary CT Findings of Visceral Larva Migrans due to Ascaris suum" by: "K. Honda, F. Okada, Y. Ando, A. Ono, S. Matsumoto, H. Mori; Oita/JP"
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pulmonary computed tomography findings of Visceral Larva Migrans caused by ascaris suum
Journal of Computer Assisted Tomography, 2007Co-Authors: Fumito Okada, Yumiko Ando, Shunro Matsumoto, Shinji Yotsumoto, Shuichi Tanoue, Masaki Wakisaka, Hiromu MoriAbstract:Objective: To retrospectively evaluate the computed tomography (CT) findings of pulmonary involvement in patients with Visceral Larva Migrans caused by Ascaris suum. Methods: Institutional review board approval was obtained, and informed consent was waived. Chest CT scans obtained between January 1994 and November 2005 in 32 patients infected with A. suum were retrospectively evaluated by 3 chest radiologists. In 4 patients who underwent surgical or transbronchial biopsy, comparisons of the CT images with the actual specimens were performed. Results: On CT scans, abnormal findings were seen in 28 patients. The most common abnormality consisted of nodules (n = 19) in which the majority had a halo of ground-glass attenuation (n = 17), followed by ground-glass attenuation (n = 18), and interlobular septal thickening (n = 14). These abnormalities were predominantly seen in the peripheral lung (n = 25). Of the 7 patients who underwent follow-up CT scans, nodules (n = 6) and ground-glass attenuation (n = 5) had migrated in 4 patients. Pathologically, these findings corresponded to marked eosinophilic infiltration into the interstitium. Conclusions: These CT findings are considered to be suggestive of thoracic involvement in patients with Visceral Larva Migrans caused by A. suum.
