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M L Tuck - One of the best experts on this subject based on the ideXlab platform.
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Weight Reduction and pharmacologic treatment in obese hypertensives.
American journal of hypertension, 2001Co-Authors: K Masuo, H Mikami, T Ogihara, M L TuckAbstract:This study was conducted to evaluate the mechanisms of Weight loss-induced blood pressure (BP) Reduction focusing, in particular, on the contributions of sympathetic nervous system activity, fasting plasma insulin, and leptin to BP levels, and to delineate the additional influence of antihypertensive drug therapy. Each of five groups of obese hypertensives were treated with the long-acting calcium channel blocker (CCB) amlodipine, the angiotensin converting enzyme (ACE) inhibitor enalapril with or without a Weight Reduction program, or a Weight Reduction program alone. The goal BP was less than 140/90 mm Hg for the pharmacologic treatment groups. The Weight Reduction program groups with or without pharmacologic treatment were divided into two groups; Weight loss groups who succeeded in Weight Reduction (> or = 10%) and nonWeight loss groups who failed in Weight Reduction ( or = 10%) than in the nonWeight loss groups (
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Weight Reduction and pharmacologic treatment in obese hypertensives.
American Journal of Hypertension, 2001Co-Authors: K Masuo, H Mikami, T Ogihara, M L TuckAbstract:Abstract This study was conducted to evaluate the mechanisms of Weight loss-induced blood pressure (BP) Reduction focusing, in particular, on the contributions of sympathetic nervous system activity, fasting plasma insulin, and leptin to BP levels, and to delineate the additional influence of antihypertensive drug therapy. Each of five groups of obese hypertensives were treated with the long-acting calcium channel blocker (CCB) amlodipine, the angiotensin converting enzyme (ACE) inhibitor enalapril with or without a Weight Reduction program, or a Weight Reduction program alone. The goal BP was less than 140/90 mm Hg for the pharmacologic treatment groups. The Weight Reduction program groups with or without pharmacologic treatment were divided into two groups; Weight loss groups who succeeded in Weight Reduction (≥10%) and nonWeight loss groups who failed in Weight Reduction ( The final dose of CCB and ACE inhibitor were less in the combined pharmacologic and Weight loss groups than in the pharmacologic treatment alone groups or in the pharmacologic and nonWeight loss groups. In the Weight Reduction groups regardless of pharmacologic treatment, the percent Reductions from baseline in plasma insulin, leptin, and norepinephrine (NE) were greater in the Weight loss groups (≥10%) than in the nonWeight loss groups ( These results show that Weight loss associated with favorable metabolic improvements and these improvements are amplified when combined with pharmacologic treatment. Therefore, Weight loss should be regarded as an essential component of any treatment program for obesity-related hypertension. A novel finding from this study is that ACE inhibition had a striking effect to lower plasma leptin. Suppression of sympathetic activity, insulinemia, and leptinemia appeared to play a role in the BP Reduction accompanying Weight loss.
Kazuo Sugawara - One of the best experts on this subject based on the ideXlab platform.
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Gender differences in the psychological response to Weight Reduction in judoists.
International journal of sport nutrition and exercise metabolism, 2006Co-Authors: Yoshiko Yoshioka, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Kazuo SugawaraAbstract:We examined gender-related differences in the psychological response to Weight Reduction in 43 judoists. Twenty-two males and 8 females who required Weight Reduction [Weight Reduction (WR) group] (the average percentages of Weight Reduction observed for males and females were 3.4% and 4.9%, respectively), and 5 males and 8 females who did not require Weight Reduction (non-WR group). The POMS scores were measured before and after Weight Reduction. The TMD (total mood disturbance) score in POMS significantly increased after Weight Reduction only in WR group males. In the female WR group, the anger and depression scores decreased after Weight Reduction, and the pre-value of the TMD score in thisgroup was relatively high. The psychological stress may be caused by anxiety engendered by the overall concept of Weight Reduction before actual Weight Reduction in females, whereas in males it may be caused by the actual Weight Reduction.
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Effects of Gender-Related Weight Reduction on the Physical Condition of Male and Female College Judoists
Nihon eiseigaku zasshi. Japanese journal of hygiene, 2004Co-Authors: Takashi Umeda, Yoshiko Yoshioka, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Yousuke Yamamoto, Tomomi Katagiri, Kazuo SugawaraAbstract:Objective: In order to study the gender-related effects of Weight Reduction on the physical condition of male and female college judoists during Weight Reduction periods, we examined changes in anthropometric, nutritional intake and biochemical parameters in 43 male and female college judoists 20 days (pre-Weight Reduction) before and one day (post-Weight Reduction) before the game.Methods: Subjects were divided into two groups. Thirty subjects (22 males, 8 females) who required Weight Reduction were defined as the Weight Reduction (WR) group, and the remaining 13 subjects (5 males, 8 females) were defined as the non-Reduction (non-WR) group.Results: In both WR groups, anthropometric parameters and nutritional intake significantly decreased after Weight Reduction compared to the pre-values. The change ratios of nutritional intake during the Weight Reduction period in the female WR group were higher than those in the male WR group. Serum lipids and electrolytes significantly decreased after the Weight Reduction compared to the pre-values in both WR groups. In the female WR group, Cr and UA significantly increased after the Weight Reduction compared to the pre-values. Although it was not significant, Ht increased after the Weight Reduction compared to the pre-values only in the female WR group. TP, Cr, UA, BUN, CK, LDH and IgA significantly increased after the Weight Reduction compared to the pre-values in the male WR group. In contrast, in both non-WR groups, these parameters did not change significantly during the research period.Conclusions: Our findings suggest that nutritional exhaustion and dehydration may be the major effects brought about by energy and fluid restriction in female college judoists during a Weight Reduction period. On the other hand, in male college judoists undergoing Weight Reduction, the data suggest that muscle damage and myogenic protein catabolism may be caused chiefly by exercise. These differences may be due to the difference in the method of Weight Reduction for the different genders, namely, mainly exercise in males and mainly energy and fluid restriction in females.
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Effects of Weight Reduction on neutrophil phagocytic activity and oxidative burst activity in female judoists.
Luminescence : the journal of biological and chemical luminescence, 2003Co-Authors: Masahiro Suzuki, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Noriko Mochida, Tadashi Shimoyama, Toshiyuki Mashiko, Kazuo SugawaraAbstract:This study investigated the effects of short-term Weight Reduction on neutrophil functions in female judoists. Sixteen actively competing female judoists were divided into two groups. Eight who required Weight Reduction were defined as the Weight Reduction group, and the remaining eight were used as the control. Blood samples were taken before, immediately after and 8 days after the match. Phagocytic activity and oxidative burst activity of neutrophils were measured by flow cytometry. In the Weight Reduction group, the phagocytic activity per cell decreased significantly at the end of Weight Reduction compared with the control group. The rate of neutrophils producing reactive oxygen species and the oxidative burst activity per cell increased significantly at the end of Weight Reduction in both the control and the Weight Reduction groups. We concluded that Weight Reduction, consisting of both intense exercise and energy restriction, might possibly cause both an increase in oxidative burst activity and decrease in neutrophil phagocytic activity in female judoists. However, although exercise increased oxidative burst activity, it did not affect neutrophil phagocytic activity alone. Therefore, to avoid this problem, female judoists are recommended to keep their Weight within those limits determined by their class, and which can be reduced by exercise. Copyright © 2003 John Wiley & Sons, Ltd.
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Depressed humoral immunity after Weight Reduction in competitive judoists.
Luminescence : the journal of biological and chemical luminescence, 2002Co-Authors: Seikou Ohta, Takashi Umeda, Shigeyuki Nakaji, Katsuhiko Suzuki, Manabu Totsuka, Kazuo SugawaraAbstract:We studied changes in serum opsonic activity (SOA) in male judoists who were engaged in active Weight Reduction. Serum immunoglobulins, complements and SOA, measured by neutrophil-associated chemiluminescence responses, were investigated 20 days, 7 days and 1 day before a competition and 5 days after the competition. In addition, muscle strength and anaerobic work capacity, as well as body composition, were also determined. A dietary survey was conducted daily during the observation period. Body Weight decreased by 4.2 kg over 19 days. SOA significantly decreased 5 days after the competition, as well as the concentrations of serum immunoglobulins, complements and total proteins. These trends were noted in the marked Weight Reduction group (i.e. Reduction Weight of body fat/body fat Weight before Weight Reduction > or = 25%) more than the slight Reduction group (
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The effect of the Weight Reduction on the salivary cortisol levels of judo players.
Environmental health and preventive medicine, 2001Co-Authors: Masahiro Toda, Takashi Umeda, Shigeyuki Nakaji, Kanehisa Morimoto, Sanae Fukuda, Kazuo SugawaraAbstract:The purpose of this study was to investigate the effect of Weight Reduction prior to a competition on the salivary cortisol level for first-rate judo players. Subjects were divided into three groups by the Weight Reduction rate. On the day before the competition, the cortisol levels of the low- and high-Weight Reduction group showed a tendency to decrease and were significantly lower than that of the non-Weight Reduction group (p
K Masuo - One of the best experts on this subject based on the ideXlab platform.
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Weight Reduction and pharmacologic treatment in obese hypertensives.
American journal of hypertension, 2001Co-Authors: K Masuo, H Mikami, T Ogihara, M L TuckAbstract:This study was conducted to evaluate the mechanisms of Weight loss-induced blood pressure (BP) Reduction focusing, in particular, on the contributions of sympathetic nervous system activity, fasting plasma insulin, and leptin to BP levels, and to delineate the additional influence of antihypertensive drug therapy. Each of five groups of obese hypertensives were treated with the long-acting calcium channel blocker (CCB) amlodipine, the angiotensin converting enzyme (ACE) inhibitor enalapril with or without a Weight Reduction program, or a Weight Reduction program alone. The goal BP was less than 140/90 mm Hg for the pharmacologic treatment groups. The Weight Reduction program groups with or without pharmacologic treatment were divided into two groups; Weight loss groups who succeeded in Weight Reduction (> or = 10%) and nonWeight loss groups who failed in Weight Reduction ( or = 10%) than in the nonWeight loss groups (
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Weight Reduction and pharmacologic treatment in obese hypertensives.
American Journal of Hypertension, 2001Co-Authors: K Masuo, H Mikami, T Ogihara, M L TuckAbstract:Abstract This study was conducted to evaluate the mechanisms of Weight loss-induced blood pressure (BP) Reduction focusing, in particular, on the contributions of sympathetic nervous system activity, fasting plasma insulin, and leptin to BP levels, and to delineate the additional influence of antihypertensive drug therapy. Each of five groups of obese hypertensives were treated with the long-acting calcium channel blocker (CCB) amlodipine, the angiotensin converting enzyme (ACE) inhibitor enalapril with or without a Weight Reduction program, or a Weight Reduction program alone. The goal BP was less than 140/90 mm Hg for the pharmacologic treatment groups. The Weight Reduction program groups with or without pharmacologic treatment were divided into two groups; Weight loss groups who succeeded in Weight Reduction (≥10%) and nonWeight loss groups who failed in Weight Reduction ( The final dose of CCB and ACE inhibitor were less in the combined pharmacologic and Weight loss groups than in the pharmacologic treatment alone groups or in the pharmacologic and nonWeight loss groups. In the Weight Reduction groups regardless of pharmacologic treatment, the percent Reductions from baseline in plasma insulin, leptin, and norepinephrine (NE) were greater in the Weight loss groups (≥10%) than in the nonWeight loss groups ( These results show that Weight loss associated with favorable metabolic improvements and these improvements are amplified when combined with pharmacologic treatment. Therefore, Weight loss should be regarded as an essential component of any treatment program for obesity-related hypertension. A novel finding from this study is that ACE inhibition had a striking effect to lower plasma leptin. Suppression of sympathetic activity, insulinemia, and leptinemia appeared to play a role in the BP Reduction accompanying Weight loss.
Takashi Umeda - One of the best experts on this subject based on the ideXlab platform.
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Gender differences in the psychological response to Weight Reduction in judoists.
International journal of sport nutrition and exercise metabolism, 2006Co-Authors: Yoshiko Yoshioka, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Kazuo SugawaraAbstract:We examined gender-related differences in the psychological response to Weight Reduction in 43 judoists. Twenty-two males and 8 females who required Weight Reduction [Weight Reduction (WR) group] (the average percentages of Weight Reduction observed for males and females were 3.4% and 4.9%, respectively), and 5 males and 8 females who did not require Weight Reduction (non-WR group). The POMS scores were measured before and after Weight Reduction. The TMD (total mood disturbance) score in POMS significantly increased after Weight Reduction only in WR group males. In the female WR group, the anger and depression scores decreased after Weight Reduction, and the pre-value of the TMD score in thisgroup was relatively high. The psychological stress may be caused by anxiety engendered by the overall concept of Weight Reduction before actual Weight Reduction in females, whereas in males it may be caused by the actual Weight Reduction.
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Effects of Gender-Related Weight Reduction on the Physical Condition of Male and Female College Judoists
Nihon eiseigaku zasshi. Japanese journal of hygiene, 2004Co-Authors: Takashi Umeda, Yoshiko Yoshioka, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Yousuke Yamamoto, Tomomi Katagiri, Kazuo SugawaraAbstract:Objective: In order to study the gender-related effects of Weight Reduction on the physical condition of male and female college judoists during Weight Reduction periods, we examined changes in anthropometric, nutritional intake and biochemical parameters in 43 male and female college judoists 20 days (pre-Weight Reduction) before and one day (post-Weight Reduction) before the game.Methods: Subjects were divided into two groups. Thirty subjects (22 males, 8 females) who required Weight Reduction were defined as the Weight Reduction (WR) group, and the remaining 13 subjects (5 males, 8 females) were defined as the non-Reduction (non-WR) group.Results: In both WR groups, anthropometric parameters and nutritional intake significantly decreased after Weight Reduction compared to the pre-values. The change ratios of nutritional intake during the Weight Reduction period in the female WR group were higher than those in the male WR group. Serum lipids and electrolytes significantly decreased after the Weight Reduction compared to the pre-values in both WR groups. In the female WR group, Cr and UA significantly increased after the Weight Reduction compared to the pre-values. Although it was not significant, Ht increased after the Weight Reduction compared to the pre-values only in the female WR group. TP, Cr, UA, BUN, CK, LDH and IgA significantly increased after the Weight Reduction compared to the pre-values in the male WR group. In contrast, in both non-WR groups, these parameters did not change significantly during the research period.Conclusions: Our findings suggest that nutritional exhaustion and dehydration may be the major effects brought about by energy and fluid restriction in female college judoists during a Weight Reduction period. On the other hand, in male college judoists undergoing Weight Reduction, the data suggest that muscle damage and myogenic protein catabolism may be caused chiefly by exercise. These differences may be due to the difference in the method of Weight Reduction for the different genders, namely, mainly exercise in males and mainly energy and fluid restriction in females.
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Effects of Weight Reduction on neutrophil phagocytic activity and oxidative burst activity in female judoists.
Luminescence : the journal of biological and chemical luminescence, 2003Co-Authors: Masahiro Suzuki, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Noriko Mochida, Tadashi Shimoyama, Toshiyuki Mashiko, Kazuo SugawaraAbstract:This study investigated the effects of short-term Weight Reduction on neutrophil functions in female judoists. Sixteen actively competing female judoists were divided into two groups. Eight who required Weight Reduction were defined as the Weight Reduction group, and the remaining eight were used as the control. Blood samples were taken before, immediately after and 8 days after the match. Phagocytic activity and oxidative burst activity of neutrophils were measured by flow cytometry. In the Weight Reduction group, the phagocytic activity per cell decreased significantly at the end of Weight Reduction compared with the control group. The rate of neutrophils producing reactive oxygen species and the oxidative burst activity per cell increased significantly at the end of Weight Reduction in both the control and the Weight Reduction groups. We concluded that Weight Reduction, consisting of both intense exercise and energy restriction, might possibly cause both an increase in oxidative burst activity and decrease in neutrophil phagocytic activity in female judoists. However, although exercise increased oxidative burst activity, it did not affect neutrophil phagocytic activity alone. Therefore, to avoid this problem, female judoists are recommended to keep their Weight within those limits determined by their class, and which can be reduced by exercise. Copyright © 2003 John Wiley & Sons, Ltd.
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Depressed humoral immunity after Weight Reduction in competitive judoists.
Luminescence : the journal of biological and chemical luminescence, 2002Co-Authors: Seikou Ohta, Takashi Umeda, Shigeyuki Nakaji, Katsuhiko Suzuki, Manabu Totsuka, Kazuo SugawaraAbstract:We studied changes in serum opsonic activity (SOA) in male judoists who were engaged in active Weight Reduction. Serum immunoglobulins, complements and SOA, measured by neutrophil-associated chemiluminescence responses, were investigated 20 days, 7 days and 1 day before a competition and 5 days after the competition. In addition, muscle strength and anaerobic work capacity, as well as body composition, were also determined. A dietary survey was conducted daily during the observation period. Body Weight decreased by 4.2 kg over 19 days. SOA significantly decreased 5 days after the competition, as well as the concentrations of serum immunoglobulins, complements and total proteins. These trends were noted in the marked Weight Reduction group (i.e. Reduction Weight of body fat/body fat Weight before Weight Reduction > or = 25%) more than the slight Reduction group (
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The effect of the Weight Reduction on the salivary cortisol levels of judo players.
Environmental health and preventive medicine, 2001Co-Authors: Masahiro Toda, Takashi Umeda, Shigeyuki Nakaji, Kanehisa Morimoto, Sanae Fukuda, Kazuo SugawaraAbstract:The purpose of this study was to investigate the effect of Weight Reduction prior to a competition on the salivary cortisol level for first-rate judo players. Subjects were divided into three groups by the Weight Reduction rate. On the day before the competition, the cortisol levels of the low- and high-Weight Reduction group showed a tendency to decrease and were significantly lower than that of the non-Weight Reduction group (p
Shigeyuki Nakaji - One of the best experts on this subject based on the ideXlab platform.
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Gender differences in the psychological response to Weight Reduction in judoists.
International journal of sport nutrition and exercise metabolism, 2006Co-Authors: Yoshiko Yoshioka, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Kazuo SugawaraAbstract:We examined gender-related differences in the psychological response to Weight Reduction in 43 judoists. Twenty-two males and 8 females who required Weight Reduction [Weight Reduction (WR) group] (the average percentages of Weight Reduction observed for males and females were 3.4% and 4.9%, respectively), and 5 males and 8 females who did not require Weight Reduction (non-WR group). The POMS scores were measured before and after Weight Reduction. The TMD (total mood disturbance) score in POMS significantly increased after Weight Reduction only in WR group males. In the female WR group, the anger and depression scores decreased after Weight Reduction, and the pre-value of the TMD score in thisgroup was relatively high. The psychological stress may be caused by anxiety engendered by the overall concept of Weight Reduction before actual Weight Reduction in females, whereas in males it may be caused by the actual Weight Reduction.
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Effects of Gender-Related Weight Reduction on the Physical Condition of Male and Female College Judoists
Nihon eiseigaku zasshi. Japanese journal of hygiene, 2004Co-Authors: Takashi Umeda, Yoshiko Yoshioka, Shigeyuki Nakaji, Arata Kojima, Masaru Tanabe, Noriko Mochida, Yousuke Yamamoto, Tomomi Katagiri, Kazuo SugawaraAbstract:Objective: In order to study the gender-related effects of Weight Reduction on the physical condition of male and female college judoists during Weight Reduction periods, we examined changes in anthropometric, nutritional intake and biochemical parameters in 43 male and female college judoists 20 days (pre-Weight Reduction) before and one day (post-Weight Reduction) before the game.Methods: Subjects were divided into two groups. Thirty subjects (22 males, 8 females) who required Weight Reduction were defined as the Weight Reduction (WR) group, and the remaining 13 subjects (5 males, 8 females) were defined as the non-Reduction (non-WR) group.Results: In both WR groups, anthropometric parameters and nutritional intake significantly decreased after Weight Reduction compared to the pre-values. The change ratios of nutritional intake during the Weight Reduction period in the female WR group were higher than those in the male WR group. Serum lipids and electrolytes significantly decreased after the Weight Reduction compared to the pre-values in both WR groups. In the female WR group, Cr and UA significantly increased after the Weight Reduction compared to the pre-values. Although it was not significant, Ht increased after the Weight Reduction compared to the pre-values only in the female WR group. TP, Cr, UA, BUN, CK, LDH and IgA significantly increased after the Weight Reduction compared to the pre-values in the male WR group. In contrast, in both non-WR groups, these parameters did not change significantly during the research period.Conclusions: Our findings suggest that nutritional exhaustion and dehydration may be the major effects brought about by energy and fluid restriction in female college judoists during a Weight Reduction period. On the other hand, in male college judoists undergoing Weight Reduction, the data suggest that muscle damage and myogenic protein catabolism may be caused chiefly by exercise. These differences may be due to the difference in the method of Weight Reduction for the different genders, namely, mainly exercise in males and mainly energy and fluid restriction in females.
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Effects of Weight Reduction on neutrophil phagocytic activity and oxidative burst activity in female judoists.
Luminescence : the journal of biological and chemical luminescence, 2003Co-Authors: Masahiro Suzuki, Takashi Umeda, Shigeyuki Nakaji, Arata Kojima, Noriko Mochida, Tadashi Shimoyama, Toshiyuki Mashiko, Kazuo SugawaraAbstract:This study investigated the effects of short-term Weight Reduction on neutrophil functions in female judoists. Sixteen actively competing female judoists were divided into two groups. Eight who required Weight Reduction were defined as the Weight Reduction group, and the remaining eight were used as the control. Blood samples were taken before, immediately after and 8 days after the match. Phagocytic activity and oxidative burst activity of neutrophils were measured by flow cytometry. In the Weight Reduction group, the phagocytic activity per cell decreased significantly at the end of Weight Reduction compared with the control group. The rate of neutrophils producing reactive oxygen species and the oxidative burst activity per cell increased significantly at the end of Weight Reduction in both the control and the Weight Reduction groups. We concluded that Weight Reduction, consisting of both intense exercise and energy restriction, might possibly cause both an increase in oxidative burst activity and decrease in neutrophil phagocytic activity in female judoists. However, although exercise increased oxidative burst activity, it did not affect neutrophil phagocytic activity alone. Therefore, to avoid this problem, female judoists are recommended to keep their Weight within those limits determined by their class, and which can be reduced by exercise. Copyright © 2003 John Wiley & Sons, Ltd.
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Depressed humoral immunity after Weight Reduction in competitive judoists.
Luminescence : the journal of biological and chemical luminescence, 2002Co-Authors: Seikou Ohta, Takashi Umeda, Shigeyuki Nakaji, Katsuhiko Suzuki, Manabu Totsuka, Kazuo SugawaraAbstract:We studied changes in serum opsonic activity (SOA) in male judoists who were engaged in active Weight Reduction. Serum immunoglobulins, complements and SOA, measured by neutrophil-associated chemiluminescence responses, were investigated 20 days, 7 days and 1 day before a competition and 5 days after the competition. In addition, muscle strength and anaerobic work capacity, as well as body composition, were also determined. A dietary survey was conducted daily during the observation period. Body Weight decreased by 4.2 kg over 19 days. SOA significantly decreased 5 days after the competition, as well as the concentrations of serum immunoglobulins, complements and total proteins. These trends were noted in the marked Weight Reduction group (i.e. Reduction Weight of body fat/body fat Weight before Weight Reduction > or = 25%) more than the slight Reduction group (
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The effect of the Weight Reduction on the salivary cortisol levels of judo players.
Environmental health and preventive medicine, 2001Co-Authors: Masahiro Toda, Takashi Umeda, Shigeyuki Nakaji, Kanehisa Morimoto, Sanae Fukuda, Kazuo SugawaraAbstract:The purpose of this study was to investigate the effect of Weight Reduction prior to a competition on the salivary cortisol level for first-rate judo players. Subjects were divided into three groups by the Weight Reduction rate. On the day before the competition, the cortisol levels of the low- and high-Weight Reduction group showed a tendency to decrease and were significantly lower than that of the non-Weight Reduction group (p
