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Nadarajan Kaneson - One of the best experts on this subject based on the ideXlab platform.
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Psychological Stress among undergraduate medical students
The Medical journal of Malaysia, 2004Co-Authors: M S Sherina, Lekhraj Rampal, Nadarajan KanesonAbstract:The aim of this study was to determine the prevalence of Psychological Stress among medical students and to identify its symptoms and association with depression. A cross-sectional study design was used. Three-hundred and ninety-six medical students at a university in Malaysia were included in the study. Tools similar to the General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) were used to screen for Psychological Stress and depression, respectively. 41.9% of the medical students were found to have Psychological Stress, which was significantly associated with depression (chi2=4.636, df=1, p<0.05). Psychological Stress is common among medical students and is associated with depression.
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Psychological Stress AMONG UNDERGRADUATE MEDICAL STUDENTS
The Medical journal of Malaysia, 2004Co-Authors: M S Sherina, Lekhraj Rampal, Nadarajan KanesonAbstract:The aim of this study was to determine the prevalence of Psychological Stress among medical students and to identify its symptoms and association with depression. A cross-sectional study design was used. Three-hundred and ninety-six medical students at a university in Malaysia were included in the study. Tools similar to the General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) were used to screen for Psychological Stress and depression, respectively. 41.9% of the medical students were found to have Psychological Stress, which was significantly associated with depression (chi2=4.636, df=1, p
M S Sherina - One of the best experts on this subject based on the ideXlab platform.
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Psychological Stress among undergraduate medical students
The Medical journal of Malaysia, 2004Co-Authors: M S Sherina, Lekhraj Rampal, Nadarajan KanesonAbstract:The aim of this study was to determine the prevalence of Psychological Stress among medical students and to identify its symptoms and association with depression. A cross-sectional study design was used. Three-hundred and ninety-six medical students at a university in Malaysia were included in the study. Tools similar to the General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) were used to screen for Psychological Stress and depression, respectively. 41.9% of the medical students were found to have Psychological Stress, which was significantly associated with depression (chi2=4.636, df=1, p<0.05). Psychological Stress is common among medical students and is associated with depression.
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Psychological Stress AMONG UNDERGRADUATE MEDICAL STUDENTS
The Medical journal of Malaysia, 2004Co-Authors: M S Sherina, Lekhraj Rampal, Nadarajan KanesonAbstract:The aim of this study was to determine the prevalence of Psychological Stress among medical students and to identify its symptoms and association with depression. A cross-sectional study design was used. Three-hundred and ninety-six medical students at a university in Malaysia were included in the study. Tools similar to the General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) were used to screen for Psychological Stress and depression, respectively. 41.9% of the medical students were found to have Psychological Stress, which was significantly associated with depression (chi2=4.636, df=1, p
Yongjin Chen - One of the best experts on this subject based on the ideXlab platform.
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Psychological Stress may contribute to temporomandibular joint disorder in rats
Journal of Surgical Research, 2012Co-Authors: Lei Chen, Huang Fei, Guoxiong Zhu, Yongjin ChenAbstract:Abstract Background Psychological Stress is considered a possible pathogenic factor for temporomandibular joint disorders (TMJD), but few reports have supplied direct evidence. This study was designed to observe the effects of Psychological Stress on the masticatory muscles and condylar processes in rats to directly investigate the role of Psychological Stress in TMJD morbidity. Materials and methods A well-established rat communication box model was used to compare the myoelectric profiles of temporal and masseter muscles and condylar microstructure among rats in a control group, a Psychological Stress group (PS group), and a diazepam (anxiolytic agent) injection group (PS + DI group). Reverse-transcription polymerase chain reaction was also used to analyze the substance P mRNA and calcitonin gene–related peptide mRNA levels expressed in condylar cartilages during different phases of Psychological Stress. Results At 1, 3, and 5 wk, both temporal and masseter muscles in the PS group exhibited a significantly higher electrical potential in relaxation than those in the control group ( P P P Conclusions Psychological Stress may play an important role in the formation of TMJD.
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Psychological Stress induces alterations in temporomandibular joint ultrastructure in a rat model of temporomandibular disorder.
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2011Co-Authors: Gaoyi Wu, Yucheng Su, Yongjin Chen, Lei Chen, Yanliang WangAbstract:Objective The objective of this study was to investigate the effects of Psychological Stress on temporomandibular disorder (TMD). Study design A communication box was used to induce Psychological Stress (PS) in rats. Then, the ultrastructure of temporomandibular was observed using scanning electron microscopy. Interleukin-1 (IL-1) and IL-6 were measured with reverse transcription polymerase chain reaction. Results The PS group showed evidence of ultrastructural changes in the condyle and articular disk after stimulation, i.e., incomplete gelatinlike material was observed on the condyle after 1 week of PS, wider waves on the articular disk and exposed condylar collagen were observed after 3 weeks of PS, and cracks were apparent on the surface of the condyle. The expression of IL-1 and IL-6 in the condyle cartilage significantly increased after exposure to Psychological Stress. Conclusions These results indicate that Psychological Stress induces ultrastructure alterations in the temporomandibular joint and plays an important role in TMD.
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Psychological Stress induces temporary masticatory muscle mechanical sensitivity in rats.
BioMed Research International, 2011Co-Authors: Fei Huang, Min Zhang, Yongjin ChenAbstract:To explore the relationship between Psychological Stress and masticatory muscle pain, we created a communication Stress animal model to determine whether Psychological Stress could induce increased mechanical sensitivity in masticatory muscles and to study the changes of mechanical nociceptive thresholds after Stress removal. Forty-eight male Sprague-Dawley rats were divided into a control group (CON), a foot-shocked group (FS, including 3 subgroups recorded as FS-1, FS-2, and FS-3), a Psychological Stress group (PS), and a drug treatment group (DT). PS and DT rats were confined in a communication box for one hour a day to observe the Psychological responses of neighboring FS rats.Measurements of the mechanical nociceptive thresholds of the bilateral temporal and masseter muscles showed a stimulus-response relationship between Psychological Stress and muscle mechanical sensitivity. The DT rats, who received a diazepam injection, showed almost the same mechanical sensitivity of the masticatory muscles to that of the control in response to Psychological Stress. Fourteen days after the Psychological Stressor was removed, the mechanical nociceptive thresholds returned to normal. These findings suggest that Psychological Stress is directly related to masticatory muscle pain. Removal of the Stressor could be a useful method for relieving mechanical sensitivity increase induced by Psychological Stress.
J R Jennings - One of the best experts on this subject based on the ideXlab platform.
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Psychological Stress and the progression of carotid artery disease
Journal of Hypertension, 1997Co-Authors: Peter Barnett, J D Spence, Stephen B Manuck, J R JenningsAbstract:BackgroundWe examined the relation between cardiovascular reactivity (the response of the cardiovascular system to Psychological Stress) and the severity and progression of carotid atherosclerosis.MethodsUsing duplex ultrasonography, we measured the change in the area of all detectable plaques in th
Manish Nivsarkar - One of the best experts on this subject based on the ideXlab platform.
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role of cortisol and superoxide dismutase in Psychological Stress induced anovulation
General and Comparative Endocrinology, 2016Co-Authors: Manika Kala, Manish NivsarkarAbstract:Abstract Stress has been identified as a potential trigger for reproductive dysfunctions, but the psycho-physiological pathway behind the effect of Stress on ovulation remains unexplored. The present research work highlights the plausible mechanism of Psychological Stress on ovulation in mice by targeting superoxide dismutase (SOD), an enzyme involved in ovulation. For this, three consecutive studies were carried out. The first study aimed to determine the effect of Psychological Stress induced change in cortisol level, behavioral parameters and normal estrous cyclicity. The effect on mRNA expression of SOD subtypes, follicular growth in histological sections of ovaries and the difference in oocyte quality and number, upon superovulation were assessed in the subsequent studies. The results indicate that Psychological Stress model causes an increase in cortisol level ( p ⩽ 0.05) with development of anhedonia, depression and anxiety. An irregular estrous cycle was observed in Stressed mice with an upregulation in mRNA expression of SOD subtypes. Histological sections revealed an increase in atretic antral follicle with an impaired follicular development. Moreover, immature oocytes were obtained from superovulated Stressed mice. The study concludes that Psychological Stress results in anovulation which may be due to increase in cortisol level and SOD activity in Stressed mice.
