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David J. Prezant - One of the best experts on this subject based on the ideXlab platform.
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Airway Disease in Rescue/Recovery Workers: Recent Findings from the World Trade Center Collapse
Current Allergy and Asthma Reports, 2017Co-Authors: Krystal L. Cleven, Mayris P. Webber, Rachel Zeig-owens, Kerry M. Hena, David J. PrezantAbstract:Purpose of Review Our goal is to summarize the airway disease literature since September 11, 2001 (9/11), focusing on studies published since 2011 in World Trade Center-exposed rescue/recovery workers. Recent Findings Since 2011, studies have confirmed relationships between initial World Trade Center exposure intensity, severity of symptoms, airway disease diagnoses, and biomarkers of disease progression. Summary Studies continue to document ongoing morbidity in rescue/recovery workers over 10 years after 9/11. Future research should further identify correlates of symptom persistence and new airway disease diagnoses. The unique characteristics of the airway diseases in this population warrant ongoing monitoring and treatment.
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Trends in Respiratory Diagnoses and Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2005-2010
Preventive medicine, 2011Co-Authors: Jessica Weakley, Kerry J. Kelly, Charles B Hall, Hillel W Cohen, Mayris P. Webber, Jackson Gustave, David J. PrezantAbstract:Abstract Objectives To compare the prevalence of self-reported respiratory diagnoses in World Trade Center-exposed Fire Department of New York City firefighters to the prevalence in demographically similar National Health Interview Survey participants by year; and, 2) to describe the prevalence of World Trade Center-related symptoms up to 9 years post-9/11. Methods We analyzed 45,988 questionnaires completed by 10,999 firefighters from 10/2/2001 to 9/11/2010. For comparison of diagnosis rates, we calculated 95% confidence intervals around yearly firefighter prevalence estimates and generated odds ratios and confidence intervals to compare the odds of diagnoses in firefighters to the National Health Interview Survey prevalence, by smoking status. Results Overall, World Trade Center-exposed firefighters had higher respiratory diagnosis rates than the National Health Interview Survey; Fire Department of New York City rates also varied less by smoking status. In 2009, bronchitis rates in firefighters aged 45–65 were 13.3 in smokers versus 13.1 in never-smokers while in the National Health Interview Survey, bronchitis rates were doubled for smokers: 4.3 vs. 2.1. In serial cross-sectional analyses, the prevalence of most symptoms stabilized by 2005, at ~ 10% for cough to ~ 48% for sinus. Conclusions We found generally higher rates of respiratory diagnoses in World Trade Center-exposed firefighters compared to US males, regardless of smoking status. This underscores the impact of World Trade Center exposure and the need for continued monitoring and treatment of this population.
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Trends in Respiratory Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2001–2005
Environmental health perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
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trends in respiratory symptoms of firefighters exposed to the World Trade Center disaster 2001 2005
Environmental Health Perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
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World Trade Center Cough Syndrome and Its Treatment
Lung, 2008Co-Authors: David J. PrezantAbstract:To date, the main respiratory health consequence from the collapse of the World Trade Center (WTC) on September 11, 2001 has been the “WTC Cough Syndrome” (chronic rhinosinusitis, asthma, and/or bronchitis, often complicated by gastroesophageal reflux dysfunction). Syndrome incidence and severity have been linked to WTC dust exposure intensity. While it is too early to ascertain long-term effects of WTC dust exposure, effective treatment guidelines have been designed through a collaborative effort by the three established Centers of excellence for WTC medical monitoring and treatment and the WTC Registry. These treatment recommendations are described here.
Mayris P. Webber - One of the best experts on this subject based on the ideXlab platform.
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Airway Disease in Rescue/Recovery Workers: Recent Findings from the World Trade Center Collapse
Current Allergy and Asthma Reports, 2017Co-Authors: Krystal L. Cleven, Mayris P. Webber, Rachel Zeig-owens, Kerry M. Hena, David J. PrezantAbstract:Purpose of Review Our goal is to summarize the airway disease literature since September 11, 2001 (9/11), focusing on studies published since 2011 in World Trade Center-exposed rescue/recovery workers. Recent Findings Since 2011, studies have confirmed relationships between initial World Trade Center exposure intensity, severity of symptoms, airway disease diagnoses, and biomarkers of disease progression. Summary Studies continue to document ongoing morbidity in rescue/recovery workers over 10 years after 9/11. Future research should further identify correlates of symptom persistence and new airway disease diagnoses. The unique characteristics of the airway diseases in this population warrant ongoing monitoring and treatment.
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Trends in Respiratory Diagnoses and Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2005-2010
Preventive medicine, 2011Co-Authors: Jessica Weakley, Kerry J. Kelly, Charles B Hall, Hillel W Cohen, Mayris P. Webber, Jackson Gustave, David J. PrezantAbstract:Abstract Objectives To compare the prevalence of self-reported respiratory diagnoses in World Trade Center-exposed Fire Department of New York City firefighters to the prevalence in demographically similar National Health Interview Survey participants by year; and, 2) to describe the prevalence of World Trade Center-related symptoms up to 9 years post-9/11. Methods We analyzed 45,988 questionnaires completed by 10,999 firefighters from 10/2/2001 to 9/11/2010. For comparison of diagnosis rates, we calculated 95% confidence intervals around yearly firefighter prevalence estimates and generated odds ratios and confidence intervals to compare the odds of diagnoses in firefighters to the National Health Interview Survey prevalence, by smoking status. Results Overall, World Trade Center-exposed firefighters had higher respiratory diagnosis rates than the National Health Interview Survey; Fire Department of New York City rates also varied less by smoking status. In 2009, bronchitis rates in firefighters aged 45–65 were 13.3 in smokers versus 13.1 in never-smokers while in the National Health Interview Survey, bronchitis rates were doubled for smokers: 4.3 vs. 2.1. In serial cross-sectional analyses, the prevalence of most symptoms stabilized by 2005, at ~ 10% for cough to ~ 48% for sinus. Conclusions We found generally higher rates of respiratory diagnoses in World Trade Center-exposed firefighters compared to US males, regardless of smoking status. This underscores the impact of World Trade Center exposure and the need for continued monitoring and treatment of this population.
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lung function in rescue workers at the World Trade Center after 7 years
The New England Journal of Medicine, 2010Co-Authors: Thomas K. Aldrich, Charles B Hall, Hillel W Cohen, Mayris P. Webber, Jackson Gustave, Rachel Zeigowens, Kaitlyn Cosenza, Vasilios Christodoulou, Lara Glass, Fairouz AlothmanAbstract:Background The terrorist attacks on the World Trade Center on September 11, 2001, exposed thousands of Fire Department of New York City (FDNY) rescue workers to dust, leading to substantial declines in lung function in the first year. We sought to determine the longer-term effects of exposure. Methods Using linear mixed models, we analyzed the forced expiratory volume in 1 second (FEV1) of both active and retired FDNY rescue workers on the basis of spirometry routinely performed at intervals of 12 to 18 months from March 12, 2000, to September 11, 2008. Results Of the 13,954 FDNY workers who were present at the World Trade Center between September 11, 2001, and September 24, 2001, a total of 12,781 (91.6%) participated in this study, contributing 61,746 quality-screened spirometric measurements. The median follow-up was 6.1 years for firefighters and 6.4 years for emergency-medical-services (EMS) workers. In the first year, the mean FEV1 decreased significantly for all workers, more for firefighters who h...
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Trends in Respiratory Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2001–2005
Environmental health perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
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trends in respiratory symptoms of firefighters exposed to the World Trade Center disaster 2001 2005
Environmental Health Perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
Hillel W Cohen - One of the best experts on this subject based on the ideXlab platform.
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Trends in Respiratory Diagnoses and Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2005-2010
Preventive medicine, 2011Co-Authors: Jessica Weakley, Kerry J. Kelly, Charles B Hall, Hillel W Cohen, Mayris P. Webber, Jackson Gustave, David J. PrezantAbstract:Abstract Objectives To compare the prevalence of self-reported respiratory diagnoses in World Trade Center-exposed Fire Department of New York City firefighters to the prevalence in demographically similar National Health Interview Survey participants by year; and, 2) to describe the prevalence of World Trade Center-related symptoms up to 9 years post-9/11. Methods We analyzed 45,988 questionnaires completed by 10,999 firefighters from 10/2/2001 to 9/11/2010. For comparison of diagnosis rates, we calculated 95% confidence intervals around yearly firefighter prevalence estimates and generated odds ratios and confidence intervals to compare the odds of diagnoses in firefighters to the National Health Interview Survey prevalence, by smoking status. Results Overall, World Trade Center-exposed firefighters had higher respiratory diagnosis rates than the National Health Interview Survey; Fire Department of New York City rates also varied less by smoking status. In 2009, bronchitis rates in firefighters aged 45–65 were 13.3 in smokers versus 13.1 in never-smokers while in the National Health Interview Survey, bronchitis rates were doubled for smokers: 4.3 vs. 2.1. In serial cross-sectional analyses, the prevalence of most symptoms stabilized by 2005, at ~ 10% for cough to ~ 48% for sinus. Conclusions We found generally higher rates of respiratory diagnoses in World Trade Center-exposed firefighters compared to US males, regardless of smoking status. This underscores the impact of World Trade Center exposure and the need for continued monitoring and treatment of this population.
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lung function in rescue workers at the World Trade Center after 7 years
The New England Journal of Medicine, 2010Co-Authors: Thomas K. Aldrich, Charles B Hall, Hillel W Cohen, Mayris P. Webber, Jackson Gustave, Rachel Zeigowens, Kaitlyn Cosenza, Vasilios Christodoulou, Lara Glass, Fairouz AlothmanAbstract:Background The terrorist attacks on the World Trade Center on September 11, 2001, exposed thousands of Fire Department of New York City (FDNY) rescue workers to dust, leading to substantial declines in lung function in the first year. We sought to determine the longer-term effects of exposure. Methods Using linear mixed models, we analyzed the forced expiratory volume in 1 second (FEV1) of both active and retired FDNY rescue workers on the basis of spirometry routinely performed at intervals of 12 to 18 months from March 12, 2000, to September 11, 2008. Results Of the 13,954 FDNY workers who were present at the World Trade Center between September 11, 2001, and September 24, 2001, a total of 12,781 (91.6%) participated in this study, contributing 61,746 quality-screened spirometric measurements. The median follow-up was 6.1 years for firefighters and 6.4 years for emergency-medical-services (EMS) workers. In the first year, the mean FEV1 decreased significantly for all workers, more for firefighters who h...
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Trends in Respiratory Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2001–2005
Environmental health perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
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trends in respiratory symptoms of firefighters exposed to the World Trade Center disaster 2001 2005
Environmental Health Perspectives, 2009Co-Authors: Mayris P. Webber, Hillel W Cohen, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry E. Kelly, David J. PrezantAbstract:BackgroundRespiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented in WTC-exposed work...
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pulmonary function after exposure to the World Trade Center collapse in the new york city fire department
American Journal of Respiratory and Critical Care Medicine, 2006Co-Authors: Gisela I. Banauch, Michael D. Weiden, Thomas K. Aldrich, Kerry J. Kelly, Charles B Hall, Hillel W Cohen, Vasillios Christodoulou, Nicole Arcentales, David J. PrezantAbstract:Rationale: On September 11, 2001, the World Trade Center collapse created an enormous urban disaster site with high levels of airborne pollutants. First responders, rescue and recovery workers, and residents have since reported respiratory symptoms and developed pulmonary function abnormalities. Objectives: To quantify respiratory health effects of World Trade Center exposure in the New York City Fire Department. Measurements: Longitudinal study of pulmonary function in 12,079 New York City Fire Department rescue workers employed on or before 09/11/2001. Between 01/01/1997 and 09/11/2002, 31,994 spirometries were obtained and the FEV1 and FVC were analyzed for differences according to estimated World Trade Center exposure intensity. Adjusted average FEV1 during the first year after 09/11/2001 was compared with the 5 yr before 09/11/2001. Median time between 09/11/2001 and a worker's first spirometry afterwards was 3 mo; 90% were assessed within 5 mo. Main Results: World Trade Center–exposed workers experienced a substantial reduction in adjusted average FEV1 during the year after 09/11/2001 (372 ml; 95% confidence interval, 364–381 ml; p < 0.001) This exposure-related FEV1 decrement equaled 12 yr of aging-related FEV1 decline. Moreover, exposure intensity assessed by initial arrival time at the World Trade Center site correlated linearly with FEV1 reduction in an exposure intensity–response gradient (p = 0.048). Respiratory symptoms also predicted a further FEV1 decrease (p < 0.001). Similar findings were observed for adjusted average FVC. Conclusions: World Trade Center exposure produced a substantial reduction in pulmonary function in New York City Fire Department rescue workers during the first year after 09/11/2001.
Gisela I. Banauch - One of the best experts on this subject based on the ideXlab platform.
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pulmonary function after exposure to the World Trade Center collapse in the new york city fire department
American Journal of Respiratory and Critical Care Medicine, 2006Co-Authors: Gisela I. Banauch, Michael D. Weiden, Thomas K. Aldrich, Kerry J. Kelly, Charles B Hall, Hillel W Cohen, Vasillios Christodoulou, Nicole Arcentales, David J. PrezantAbstract:Rationale: On September 11, 2001, the World Trade Center collapse created an enormous urban disaster site with high levels of airborne pollutants. First responders, rescue and recovery workers, and residents have since reported respiratory symptoms and developed pulmonary function abnormalities. Objectives: To quantify respiratory health effects of World Trade Center exposure in the New York City Fire Department. Measurements: Longitudinal study of pulmonary function in 12,079 New York City Fire Department rescue workers employed on or before 09/11/2001. Between 01/01/1997 and 09/11/2002, 31,994 spirometries were obtained and the FEV1 and FVC were analyzed for differences according to estimated World Trade Center exposure intensity. Adjusted average FEV1 during the first year after 09/11/2001 was compared with the 5 yr before 09/11/2001. Median time between 09/11/2001 and a worker's first spirometry afterwards was 3 mo; 90% were assessed within 5 mo. Main Results: World Trade Center–exposed workers experienced a substantial reduction in adjusted average FEV1 during the year after 09/11/2001 (372 ml; 95% confidence interval, 364–381 ml; p < 0.001) This exposure-related FEV1 decrement equaled 12 yr of aging-related FEV1 decline. Moreover, exposure intensity assessed by initial arrival time at the World Trade Center site correlated linearly with FEV1 reduction in an exposure intensity–response gradient (p = 0.048). Respiratory symptoms also predicted a further FEV1 decrease (p < 0.001). Similar findings were observed for adjusted average FVC. Conclusions: World Trade Center exposure produced a substantial reduction in pulmonary function in New York City Fire Department rescue workers during the first year after 09/11/2001.
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Pulmonary disease in rescue workers at the World Trade Center site.
Current opinion in pulmonary medicine, 2005Co-Authors: Gisela I. Banauch, Atiya Dhala, David J. PrezantAbstract:Purpose of reviewThe catastrophic collapse of the World Trade Center (WTC) towers on September 11, 2001 created a large-scale disaster site in a densely populated urban environment. Over the ensuing months, tens of thousands of rescue, recovery and cleanup workers, volunteers, and residents of the a
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Cough and Bronchial Responsiveness in Firefighters at the World Trade Center Site
The New England journal of medicine, 2002Co-Authors: David J. Prezant, Michael D. Weiden, Gisela I. Banauch, Georgeann Mcguinness, William N. Rom, Thomas K. Aldrich, Kerry J. KellyAbstract:Background Workers from the Fire Department of New York City were exposed to a variety of inhaled materials during and after the collapse of the World Trade Center. We evaluated clinical features in a series of 332 firefighters in whom severe cough developed after exposure and the prevalence and severity of bronchial hyperreactivity in firefighters without severe cough classified according to the level of exposure. Methods “World Trade Center cough” was defined as a persistent cough that developed after exposure to the site and was accompanied by respiratory symptoms severe enough to require medical leave for at least four weeks. Evaluation of exposed firefighters included completion of a standard questionnaire, spirometry, airway-responsiveness testing, and chest imaging. Results In the first six months after September 11, 2001, World Trade Center cough occurred in 128 of 1636 firefighters with a high level of exposure (8 percent), 187 of 6958 with a moderate level of exposure (3 percent), and 17 of 1320...
Michael Sadler - One of the best experts on this subject based on the ideXlab platform.
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Penetrating axillary trauma in a survivor of the World Trade Center disaster
Emergency radiology, 2002Co-Authors: Pradeep Albert, Daniel Del Prado, Steven Karidas, Richard Neff, Michael SadlerAbstract:Penetrating axillary trauma is classically associated with gunshot wounds or stab wounds, and it is a cause for concern because of the high risk of vascular injury. We report a case of penetrating axillary trauma to a victim of the World Trade Center disaster. In this case report, we discuss the CT and angiographic findings of both blunt and penetrating axillary injury, and present a diagnostic algorithm.
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Bystander trauma in the World Trade Center disaster
Emergency radiology, 2002Co-Authors: Pradeep Albert, Jeremy Handel, Paula Yeghiayan, Michael SadlerAbstract:We present the CT and clinical findings in a 21-year old male who presented to the emergency department following bystander trauma during the rescue effort of the World Trade Center disaster.
