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Andreas Gamillscheg - One of the best experts on this subject based on the ideXlab platform.

  • left ventricular long axis function reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of Z Score values
    American Heart Journal, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Andreas Gamillscheg
    Abstract:

    Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m²). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. Results The MAPSE ranged from a mean of 0.57 cm (Z-Score ±2: 0.38-0.76 cm) in neonates to 1.63 cm (Z-Score ±2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age ( r = 0.87, P r = 0.89, P r = 0.28, P Conclusions Z-Scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future.

  • reference values of tricuspid annular peak systolic velocity in healthy pediatric patients calculation of Z Score and comparison to tricuspid annular plane systolic excursion
    American Journal of Cardiology, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Gerhard Cvirn, Andreas Gamillscheg
    Abstract:

    The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m 2 ). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (Z Score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (Z Score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the Z Scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.

  • systolic right ventricular function in preterm and term neonates reference values of the tricuspid annular plane systolic excursion tapse in 258 patients and calculation of Z Score values
    Neonatology, 2011
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Peter Fritsch, Gerhard Cvirn, Berndt Urlesberger, Wolfgang Raith, Verena Halb, Andreas Gamillscheg
    Abstract:

    Background: The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children. Objective: We determined growth- and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates. Methods: A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530–4,200 g). Results: The TAPSE ranged from a mean of 0.44 cm (Z-Score ±2: 0.30–0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-Score ±2: 0.85–1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson’s correlation coefficient was 0.93 for week of gestation – TAPSE (p Conclusion: Z-Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future.

  • right ventricular function in infants children and adolescents reference values of the tricuspid annular plane systolic excursion tapse in 640 healthy patients and calculation of Z Score values
    Journal of The American Society of Echocardiography, 2009
    Co-Authors: Martin Koestenberger, William Ravekes, Bernd Heinzl, Andrea Fandl, Andreas Gamillscheg, Allen D Everett, Hans Peter Stueger, Gerhard Cvirn, Arnulf Boysen, Bert Nagel
    Abstract:

    Background Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults. The aim of this study was to determine growth-related changes in TAPSE to establish references values. Methods A prospective study was conducted in a group of 640 healthy pediatric patients (age range, 1 day to 18 years; body surface area range, 0.12-2.25 m 2 ). The effects of age and body surface area on TAPSE were determined. Results TAPSE ranged from a mean of 0.91 cm ( Z Score ± 3, 0.56-1.26 cm) in neonates to 2.47 cm ( Z Score ± 3, 1.84-3.10 cm) in 18-year-olds. TAPSE values showed positive correlations with age and body surface area. There was no significant difference in TAPSE values between female or male children. Conclusion In this study, Z Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in patients with congenital heart disease in the future.

Martin Koestenberger - One of the best experts on this subject based on the ideXlab platform.

  • left ventricular long axis function reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of Z Score values
    American Heart Journal, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Andreas Gamillscheg
    Abstract:

    Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m²). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. Results The MAPSE ranged from a mean of 0.57 cm (Z-Score ±2: 0.38-0.76 cm) in neonates to 1.63 cm (Z-Score ±2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age ( r = 0.87, P r = 0.89, P r = 0.28, P Conclusions Z-Scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future.

  • reference values of tricuspid annular peak systolic velocity in healthy pediatric patients calculation of Z Score and comparison to tricuspid annular plane systolic excursion
    American Journal of Cardiology, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Gerhard Cvirn, Andreas Gamillscheg
    Abstract:

    The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m 2 ). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (Z Score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (Z Score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the Z Scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.

  • systolic right ventricular function in preterm and term neonates reference values of the tricuspid annular plane systolic excursion tapse in 258 patients and calculation of Z Score values
    Neonatology, 2011
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Peter Fritsch, Gerhard Cvirn, Berndt Urlesberger, Wolfgang Raith, Verena Halb, Andreas Gamillscheg
    Abstract:

    Background: The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children. Objective: We determined growth- and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates. Methods: A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530–4,200 g). Results: The TAPSE ranged from a mean of 0.44 cm (Z-Score ±2: 0.30–0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-Score ±2: 0.85–1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson’s correlation coefficient was 0.93 for week of gestation – TAPSE (p Conclusion: Z-Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future.

  • right ventricular function in infants children and adolescents reference values of the tricuspid annular plane systolic excursion tapse in 640 healthy patients and calculation of Z Score values
    Journal of The American Society of Echocardiography, 2009
    Co-Authors: Martin Koestenberger, William Ravekes, Bernd Heinzl, Andrea Fandl, Andreas Gamillscheg, Allen D Everett, Hans Peter Stueger, Gerhard Cvirn, Arnulf Boysen, Bert Nagel
    Abstract:

    Background Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults. The aim of this study was to determine growth-related changes in TAPSE to establish references values. Methods A prospective study was conducted in a group of 640 healthy pediatric patients (age range, 1 day to 18 years; body surface area range, 0.12-2.25 m 2 ). The effects of age and body surface area on TAPSE were determined. Results TAPSE ranged from a mean of 0.91 cm ( Z Score ± 3, 0.56-1.26 cm) in neonates to 2.47 cm ( Z Score ± 3, 1.84-3.10 cm) in 18-year-olds. TAPSE values showed positive correlations with age and body surface area. There was no significant difference in TAPSE values between female or male children. Conclusion In this study, Z Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in patients with congenital heart disease in the future.

Bert Nagel - One of the best experts on this subject based on the ideXlab platform.

  • left ventricular long axis function reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of Z Score values
    American Heart Journal, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Andreas Gamillscheg
    Abstract:

    Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m²). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. Results The MAPSE ranged from a mean of 0.57 cm (Z-Score ±2: 0.38-0.76 cm) in neonates to 1.63 cm (Z-Score ±2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age ( r = 0.87, P r = 0.89, P r = 0.28, P Conclusions Z-Scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future.

  • reference values of tricuspid annular peak systolic velocity in healthy pediatric patients calculation of Z Score and comparison to tricuspid annular plane systolic excursion
    American Journal of Cardiology, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Gerhard Cvirn, Andreas Gamillscheg
    Abstract:

    The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m 2 ). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (Z Score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (Z Score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the Z Scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.

  • systolic right ventricular function in preterm and term neonates reference values of the tricuspid annular plane systolic excursion tapse in 258 patients and calculation of Z Score values
    Neonatology, 2011
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Peter Fritsch, Gerhard Cvirn, Berndt Urlesberger, Wolfgang Raith, Verena Halb, Andreas Gamillscheg
    Abstract:

    Background: The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children. Objective: We determined growth- and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates. Methods: A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530–4,200 g). Results: The TAPSE ranged from a mean of 0.44 cm (Z-Score ±2: 0.30–0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-Score ±2: 0.85–1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson’s correlation coefficient was 0.93 for week of gestation – TAPSE (p Conclusion: Z-Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future.

  • right ventricular function in infants children and adolescents reference values of the tricuspid annular plane systolic excursion tapse in 640 healthy patients and calculation of Z Score values
    Journal of The American Society of Echocardiography, 2009
    Co-Authors: Martin Koestenberger, William Ravekes, Bernd Heinzl, Andrea Fandl, Andreas Gamillscheg, Allen D Everett, Hans Peter Stueger, Gerhard Cvirn, Arnulf Boysen, Bert Nagel
    Abstract:

    Background Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults. The aim of this study was to determine growth-related changes in TAPSE to establish references values. Methods A prospective study was conducted in a group of 640 healthy pediatric patients (age range, 1 day to 18 years; body surface area range, 0.12-2.25 m 2 ). The effects of age and body surface area on TAPSE were determined. Results TAPSE ranged from a mean of 0.91 cm ( Z Score ± 3, 0.56-1.26 cm) in neonates to 2.47 cm ( Z Score ± 3, 1.84-3.10 cm) in 18-year-olds. TAPSE values showed positive correlations with age and body surface area. There was no significant difference in TAPSE values between female or male children. Conclusion In this study, Z Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in patients with congenital heart disease in the future.

William Ravekes - One of the best experts on this subject based on the ideXlab platform.

  • left ventricular long axis function reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of Z Score values
    American Heart Journal, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Andreas Gamillscheg
    Abstract:

    Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m²). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. Results The MAPSE ranged from a mean of 0.57 cm (Z-Score ±2: 0.38-0.76 cm) in neonates to 1.63 cm (Z-Score ±2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age ( r = 0.87, P r = 0.89, P r = 0.28, P Conclusions Z-Scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future.

  • reference values of tricuspid annular peak systolic velocity in healthy pediatric patients calculation of Z Score and comparison to tricuspid annular plane systolic excursion
    American Journal of Cardiology, 2012
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Peter Fritsch, Andrea Fandl, T Rehak, Gerhard Cvirn, Andreas Gamillscheg
    Abstract:

    The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m 2 ). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (Z Score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (Z Score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the Z Scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.

  • systolic right ventricular function in preterm and term neonates reference values of the tricuspid annular plane systolic excursion tapse in 258 patients and calculation of Z Score values
    Neonatology, 2011
    Co-Authors: Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Peter Fritsch, Gerhard Cvirn, Berndt Urlesberger, Wolfgang Raith, Verena Halb, Andreas Gamillscheg
    Abstract:

    Background: The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children. Objective: We determined growth- and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates. Methods: A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530–4,200 g). Results: The TAPSE ranged from a mean of 0.44 cm (Z-Score ±2: 0.30–0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-Score ±2: 0.85–1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson’s correlation coefficient was 0.93 for week of gestation – TAPSE (p Conclusion: Z-Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future.

  • right ventricular function in infants children and adolescents reference values of the tricuspid annular plane systolic excursion tapse in 640 healthy patients and calculation of Z Score values
    Journal of The American Society of Echocardiography, 2009
    Co-Authors: Martin Koestenberger, William Ravekes, Bernd Heinzl, Andrea Fandl, Andreas Gamillscheg, Allen D Everett, Hans Peter Stueger, Gerhard Cvirn, Arnulf Boysen, Bert Nagel
    Abstract:

    Background Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults. The aim of this study was to determine growth-related changes in TAPSE to establish references values. Methods A prospective study was conducted in a group of 640 healthy pediatric patients (age range, 1 day to 18 years; body surface area range, 0.12-2.25 m 2 ). The effects of age and body surface area on TAPSE were determined. Results TAPSE ranged from a mean of 0.91 cm ( Z Score ± 3, 0.56-1.26 cm) in neonates to 2.47 cm ( Z Score ± 3, 1.84-3.10 cm) in 18-year-olds. TAPSE values showed positive correlations with age and body surface area. There was no significant difference in TAPSE values between female or male children. Conclusion In this study, Z Scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in patients with congenital heart disease in the future.

Christoph Tillmanns - One of the best experts on this subject based on the ideXlab platform.

  • Z Score mapping for standardiZed analysis and reporting of cardiovascular magnetic resonance modified look locker inversion recovery molli t1 data normal behavior and validation in patients with amyloidosis
    Journal of Cardiovascular Magnetic Resonance, 2020
    Co-Authors: Riccardo Kranzusch, Fabian Aus Dem Siepen, Stephanie Wiesemann, Leonora Zange, Sarah Jeuthe, Tiago Ferreira Da Silva, Titus Kuehne, Burkert Pieske, Christoph Tillmanns
    Abstract:

    T1 mapping using modified Look-Locker inversion recovery (MOLLI) provides quantitative information on myocardial tissue composition. T1 results differ between sites due to variations in hardware and software equipment, limiting the comparability of results. The aim was to test if Z-Scores can be used to compare the results of MOLLI T1 mapping from different cardiovascular magnetic resonance (CMR) platforms. First, healthy subjects (n = 15) underwent 11 combinations of native short-axis T1 mapping (four CMR systems from two manufacturers at 1.5 T and 3 T, three MOLLI schemes). Mean and standard deviation (SD) of septal myocardial T1 were derived for each combination. T1 maps were transformed into Z-Score maps based on mean and SD values using a prototype post-processing module. Second, Z-Score mapping was applied to a validation sample of patients with cardiac amyloidosis at 1.5 T (n = 25) or 3 T (n = 13). In conventional T1 analysis, results were confounded by variations in field strength, MOLLI scheme, and manufacturer-specific system characteristics. Z-Score-based analysis yielded consistent results without significant differences between any two of the combinations in part 1 of the study. In the validation sample, Z-Score mapping differentiated between patients with cardiac amyloidosis and healthy subjects with the same diagnostic accuracy as standard T1 analysis regardless of field strength. T1 analysis based on Z-Score mapping provides consistent results without significant differences due to field strengths, CMR systems, or MOLLI variants, and detects cardiac amyloidosis with the same diagnostic accuracy as conventional T1 analysis. Z-Score mapping provides a means to compare native T1 results acquired with MOLLI across different CMR platforms.