The Experts below are selected from a list of 261 Experts worldwide ranked by ideXlab platform
Jidong Zhao - One of the best experts on this subject based on the ideXlab platform.
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gold catalyzed oxidative cyclizations of o alkynyl phenyl propargyl silyl ether derivatives involving 1 2 enynyl migration synthesis of functionalized 1h isochromenes and 2h pyrans
Organic Letters, 2018Co-Authors: Jidong Zhao, Wei Xu, Xiangdong LiAbstract:A new and convenient strategy for the synthesis of functionalized 1H-Isochromene and 2H-pyran derivatives based on gold-catalyzed oxidative cyclizations of o-(alkynyl)phenyl propargyl ether derivatives has been developed. The reaction proceeds via gold-catalyzed highly regioselective oxidation, followed by 1,2-migration of an enynyl group and nucleophlic addition. Isocoumarins were also constructed through oxidative cleavage of the exocyclic double bond of the obtained 1H-Isochromenes.
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Gold-Catalyzed Oxidative Cyclizations of {o-(Alkynyl)phenyl propargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration: Synthesis of Functionalized 1H-Isochromenes and 2H-Pyrans
Organic Letters, 2018Co-Authors: Jidong Zhao, Wei Xu, Xiangdong LiAbstract:A new and convenient strategy for the synthesis of functionalized 1H-Isochromene and 2H-pyran derivatives based on gold-catalyzed oxidative cyclizations of o-(alkynyl)phenyl propargyl ether derivatives has been developed. The reaction proceeds via gold-catalyzed highly regioselective oxidation, followed by 1,2-migration of an enynyl group and nucleophlic addition. Isocoumarins were also constructed through oxidative cleavage of the exocyclic double bond of the obtained 1H-Isochromenes.
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Gold-Catalyzed Oxidative Cyclizations of {o-(Alkynyl)phenyl propargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration: Synthesis of Functionalized 1H-Isochromenes and 2H-Pyrans
Organic letters, 2018Co-Authors: Jidong Zhao, Xin Xie, Ning Sun, Yuanhong LiuAbstract:A new and convenient strategy for the synthesis of functionalized 1H-Isochromene and 2H-pyran derivatives based on gold-catalyzed oxidative cyclizations of o-(alkynyl)phenyl propargyl ether derivat...
Xiangdong Li - One of the best experts on this subject based on the ideXlab platform.
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gold catalyzed oxidative cyclizations of o alkynyl phenyl propargyl silyl ether derivatives involving 1 2 enynyl migration synthesis of functionalized 1h isochromenes and 2h pyrans
Organic Letters, 2018Co-Authors: Jidong Zhao, Wei Xu, Xiangdong LiAbstract:A new and convenient strategy for the synthesis of functionalized 1H-Isochromene and 2H-pyran derivatives based on gold-catalyzed oxidative cyclizations of o-(alkynyl)phenyl propargyl ether derivatives has been developed. The reaction proceeds via gold-catalyzed highly regioselective oxidation, followed by 1,2-migration of an enynyl group and nucleophlic addition. Isocoumarins were also constructed through oxidative cleavage of the exocyclic double bond of the obtained 1H-Isochromenes.
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Gold-Catalyzed Oxidative Cyclizations of {o-(Alkynyl)phenyl propargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration: Synthesis of Functionalized 1H-Isochromenes and 2H-Pyrans
Organic Letters, 2018Co-Authors: Jidong Zhao, Wei Xu, Xiangdong LiAbstract:A new and convenient strategy for the synthesis of functionalized 1H-Isochromene and 2H-pyran derivatives based on gold-catalyzed oxidative cyclizations of o-(alkynyl)phenyl propargyl ether derivatives has been developed. The reaction proceeds via gold-catalyzed highly regioselective oxidation, followed by 1,2-migration of an enynyl group and nucleophlic addition. Isocoumarins were also constructed through oxidative cleavage of the exocyclic double bond of the obtained 1H-Isochromenes.
Mingwu Ding - One of the best experts on this subject based on the ideXlab platform.
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one pot synthesis of 1h isochromenes and 1 2 dihydroisoquinolines by a sequential isocyanide based multicomponent wittig reaction
Organic and Biomolecular Chemistry, 2016Co-Authors: Zhirong Guan, Long Wang, Mingwu DingAbstract:A one-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-Isochromenes 7 or 1,2-dihydroisoquinolines 9 in good yields by a sequential Passerini or Ugi condensation and an intramolecular Wittig reaction in the presence of K2CO3.
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One-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction
Organic and Biomolecular Chemistry, 2016Co-Authors: Long Wang, Zhirong Guan, Mingwu DingAbstract:A one-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-Isochromenes 7 or 1,2-dihydroisoquinolines 9 in good yields by a sequential Passerini or Ugi condensation and an intramolecular Wittig reaction in the presence of K2CO3.
Long Wang - One of the best experts on this subject based on the ideXlab platform.
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one pot synthesis of 1h isochromenes and 1 2 dihydroisoquinolines by a sequential isocyanide based multicomponent wittig reaction
Organic and Biomolecular Chemistry, 2016Co-Authors: Zhirong Guan, Long Wang, Mingwu DingAbstract:A one-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-Isochromenes 7 or 1,2-dihydroisoquinolines 9 in good yields by a sequential Passerini or Ugi condensation and an intramolecular Wittig reaction in the presence of K2CO3.
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One-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction
Organic and Biomolecular Chemistry, 2016Co-Authors: Long Wang, Zhirong Guan, Mingwu DingAbstract:A one-pot synthesis of 1H-Isochromenes and 1,2-dihydroisoquinolines by a I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 5, an acid, an amine (or without), and an isocyanide gave the 1H-Isochromenes 7 or 1,2-dihydroisoquinolines 9 in good yields by a sequential Passerini or Ugi condensation and an intramolecular Wittig reaction in the presence of K2CO3.
Kang Zhao - One of the best experts on this subject based on the ideXlab platform.
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ring contraction disproportionation spirocyclization cascade reaction of isochromeno 4 3 b indol 5 11h ones synthesis of n unsubstituted spirocycles
Journal of Organic Chemistry, 2016Co-Authors: Xiang Zhang, Daisy Zhangnegrerie, Guangshuai Zhou, Yunfei Du, Kang ZhaoAbstract:An efficient ring-contraction reaction of isochromeno[4,3-b]indol-5(11H)-ones via a nucleophile-induced disproportionation/spirocyclization cascade process has been developed under mild conditions. The process realized the conversion of isochromeno[4,3-b]indol-5(11H)-ones into N-unsubstituted spiro[indoline-2,1′-isobenzofuran]-3,3′-diones and spiro[indoline-2,1′-isoindoline]-3,3′-diones in the absence of a transition-metal catalyst or oxidant. Gram-scale reaction further demonstrated the practicability of the protocol.
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Ring-Contraction Disproportionation/Spirocyclization Cascade Reaction of Isochromeno[4,3-b]indol-5(11H)-ones: Synthesis of N-Unsubstituted Spirocycles
Journal of Organic Chemistry, 2016Co-Authors: Xiang Zhang, Guangshuai Zhou, Daisy Zhang-negrerie, Yunfei Du, Kang ZhaoAbstract:An efficient ring-contraction reaction of isochromeno[4,3-b]indol-5(11H)-ones via a nucleophile-induced disproportionation/spirocyclization cascade process has been developed under mild conditions. The process realized the conversion of isochromeno[4,3-b]indol-5(11H)-ones into N-unsubstituted spiro[indoline-2,1′-isobenzofuran]-3,3′-diones and spiro[indoline-2,1′-isoindoline]-3,3′-diones in the absence of a transition-metal catalyst or oxidant. Gram-scale reaction further demonstrated the practicability of the protocol.
