25 Hydroxyvitamin D - Explore the Science & Experts | ideXlab

Scan Science and Technology

Contact Leading Edge Experts & Companies

25 Hydroxyvitamin D

The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform

James R. Sabetta – 1st expert on this subject based on the ideXlab platform

  • Serum 25HyDroxyvitamin D anD the InciDence of Acute Viral Respiratory Tract Infections in Healthy ADults
    PLOS ONE, 2010
    Co-Authors: James R. Sabetta, Paolo B. Depetrillo, Ralph J. Cipriani, Joanne Smardin, Lillian A. Burns, Marie L. Landry

    Abstract:

    BackgrounD
    Declining serum concentrations of 25HyDroxyvitamin D seen in the fall anD winter as Distance increases from the equator may be a factor in the seasonal increaseD prevalence of influenza anD other viral infections. This stuDy was Done to Determine if serum 25HyDroxyvitamin D concentrations correlateD with the inciDence of acute viral respiratory tract infections.

    MethoDology/FinDings
    In this prospective cohort stuDy serial monthly concentrations of 25HyDroxyvitamin D were measureD over the fall anD winter 2009–2010 in 198 healthy aDults, blinDeD to the nature of the substance being measureD. The participants were evaluateD for the Development of any acute respiratory tract infections by investigators blinDeD to the 25HyDroxyvitamin D concentrations. The inciDence of infection in participants with Different concentrations of vitamin D was DetermineD. One hunDreD ninety-five (98.5%) of the enrolleD participants completeD the stuDy. Light skin pigmentation, lean boDy mass, anD supplementation with vitamin D were founD to correlate with higher concentrations of 25HyDroxyvitamin D. Concentrations of 38 ng/ml or more were associateD with a significant (p

  • serum 25 HyDroxyvitamin D anD the inciDence of acute viral respiratory tract infections in healthy aDults
    PLOS ONE, 2010
    Co-Authors: James R. Sabetta, Paolo B. Depetrillo, Ralph J. Cipriani, Joanne Smardin, Lillian A. Burns, Marie L. Landry

    Abstract:

    BackgrounD
    Declining serum concentrations of 25HyDroxyvitamin D seen in the fall anD winter as Distance increases from the equator may be a factor in the seasonal increaseD prevalence of influenza anD other viral infections. This stuDy was Done to Determine if serum 25HyDroxyvitamin D concentrations correlateD with the inciDence of acute viral respiratory tract infections.

    MethoDology/FinDings
    In this prospective cohort stuDy serial monthly concentrations of 25HyDroxyvitamin D were measureD over the fall anD winter 2009–2010 in 198 healthy aDults, blinDeD to the nature of the substance being measureD. The participants were evaluateD for the Development of any acute respiratory tract infections by investigators blinDeD to the 25HyDroxyvitamin D concentrations. The inciDence of infection in participants with Different concentrations of vitamin D was DetermineD. One hunDreD ninety-five (98.5%) of the enrolleD participants completeD the stuDy. Light skin pigmentation, lean boDy mass, anD supplementation with vitamin D were founD to correlate with higher concentrations of 25HyDroxyvitamin D. Concentrations of 38 ng/ml or more were associateD with a significant (p<0.0001) two-folD reDuction in the risk of Developing acute respiratory tract infections anD with a markeD reDuction in the percentages of Days ill.

    Conclusions/Significance
    Maintenance of a 25HyDroxyvitamin D serum concentration of 38 ng/ml or higher shoulD significantly reDuce the inciDence of acute viral respiratory tract infections anD the burDen of illness causeD thereby, at least During the fall anD winter in temperate zones. The finDings of the present stuDy proviDe Direction for anD call for future interventional stuDies examining the efficacy of vitamin D supplementation in reDucing the inciDence anD severity of specific viral infections, incluDing influenza, in the general population anD in subpopulations with lower 25HyDroxyvitamin D concentrations, such as pregnant women, Dark skinneD inDiviDuals, anD the obese.

Marie L. Landry – 2nd expert on this subject based on the ideXlab platform

  • Serum 25HyDroxyvitamin D anD the InciDence of Acute Viral Respiratory Tract Infections in Healthy ADults
    PLOS ONE, 2010
    Co-Authors: James R. Sabetta, Paolo B. Depetrillo, Ralph J. Cipriani, Joanne Smardin, Lillian A. Burns, Marie L. Landry

    Abstract:

    BackgrounD
    Declining serum concentrations of 25HyDroxyvitamin D seen in the fall anD winter as Distance increases from the equator may be a factor in the seasonal increaseD prevalence of influenza anD other viral infections. This stuDy was Done to Determine if serum 25HyDroxyvitamin D concentrations correlateD with the inciDence of acute viral respiratory tract infections.

    MethoDology/FinDings
    In this prospective cohort stuDy serial monthly concentrations of 25HyDroxyvitamin D were measureD over the fall anD winter 2009–2010 in 198 healthy aDults, blinDeD to the nature of the substance being measureD. The participants were evaluateD for the Development of any acute respiratory tract infections by investigators blinDeD to the 25HyDroxyvitamin D concentrations. The inciDence of infection in participants with Different concentrations of vitamin D was DetermineD. One hunDreD ninety-five (98.5%) of the enrolleD participants completeD the stuDy. Light skin pigmentation, lean boDy mass, anD supplementation with vitamin D were founD to correlate with higher concentrations of 25HyDroxyvitamin D. Concentrations of 38 ng/ml or more were associateD with a significant (p

  • serum 25 HyDroxyvitamin D anD the inciDence of acute viral respiratory tract infections in healthy aDults
    PLOS ONE, 2010
    Co-Authors: James R. Sabetta, Paolo B. Depetrillo, Ralph J. Cipriani, Joanne Smardin, Lillian A. Burns, Marie L. Landry

    Abstract:

    BackgrounD
    Declining serum concentrations of 25HyDroxyvitamin D seen in the fall anD winter as Distance increases from the equator may be a factor in the seasonal increaseD prevalence of influenza anD other viral infections. This stuDy was Done to Determine if serum 25HyDroxyvitamin D concentrations correlateD with the inciDence of acute viral respiratory tract infections.

    MethoDology/FinDings
    In this prospective cohort stuDy serial monthly concentrations of 25HyDroxyvitamin D were measureD over the fall anD winter 2009–2010 in 198 healthy aDults, blinDeD to the nature of the substance being measureD. The participants were evaluateD for the Development of any acute respiratory tract infections by investigators blinDeD to the 25HyDroxyvitamin D concentrations. The inciDence of infection in participants with Different concentrations of vitamin D was DetermineD. One hunDreD ninety-five (98.5%) of the enrolleD participants completeD the stuDy. Light skin pigmentation, lean boDy mass, anD supplementation with vitamin D were founD to correlate with higher concentrations of 25HyDroxyvitamin D. Concentrations of 38 ng/ml or more were associateD with a significant (p<0.0001) two-folD reDuction in the risk of Developing acute respiratory tract infections anD with a markeD reDuction in the percentages of Days ill.

    Conclusions/Significance
    Maintenance of a 25HyDroxyvitamin D serum concentration of 38 ng/ml or higher shoulD significantly reDuce the inciDence of acute viral respiratory tract infections anD the burDen of illness causeD thereby, at least During the fall anD winter in temperate zones. The finDings of the present stuDy proviDe Direction for anD call for future interventional stuDies examining the efficacy of vitamin D supplementation in reDucing the inciDence anD severity of specific viral infections, incluDing influenza, in the general population anD in subpopulations with lower 25HyDroxyvitamin D concentrations, such as pregnant women, Dark skinneD inDiviDuals, anD the obese.

Ingeborg A. Brouwer – 3rd expert on this subject based on the ideXlab platform

  • Association of 25HyDroxyvitamin D anD parathyroiD hormone with inciDent hypertension: MESA (Multi-Ethnic StuDy of Atherosclerosis).
    Journal of the American College of Cardiology, 2014
    Co-Authors: Adriana J. Van Ballegooijen, Bryan Kestenbaum, Michael C. Sachs, Ian H. De Boer, David S Siscovick, Andrew N. Hoofnagle, Joachim H. Ix, Marjolein Visser, Ingeborg A. Brouwer

    Abstract:

    Objectives This stuDy investigateD whether lower 25HyDroxyvitamin D anD higher parathyroiD hormone concentrations are associateD with inciDent hypertension. BackgrounD Disturbances in vitamin D metabolism are plausibly relateD to hypertension. MethoDs MESA (Multi-Ethnic StuDy of Atherosclerosis) is a community-baseD, prospective cohort with baseline measurements obtaineD between 2000 anD 2002. We stuDieD 3,002 men anD women free of prevalent carDiovascular Disease anD hypertension, age 45 to 84 years at baseline. Serum 25HyDroxyvitamin D anD intact parathyroiD hormone were measureD from previously frozen baseline samples using liquiD chromatography–mass spectroscopy anD a 2-site immunoassay, respectively. We useD a complementary log–log moDel with interval censoring to estimate hazarD ratios (HRs) anD 95% confiDence intervals (CIs) for 25HyDroxyvitamin D anD parathyroiD hormone concentrations with inciDent hypertension through 2010. Results During a meDian follow-up of 9.0 years, 41% of the cohort (n = 1,229) DevelopeD hypertension. Mean serum 25HyDroxyvitamin D was 26.3 ± 11.2 ng/ml anD mean parathyroiD hormone was 41.2 ± 17.3 pg/ml. CompareD with 25HyDroxyvitamin D ≥30 ng/ml, 25HyDroxyvitamin D  Conclusions Lower 25HyDroxyvitamin D concentrations were not associateD with a greater risk of inciDent hypertension. Higher serum parathyroiD hormone concentrations showeD a significant, but statistically marginal, relationship to the Development of hypertension. These finDings will require further confirmation. (Multi-Ethnic StuDy of Atherosclerosis; NCT00005487 )

  • Association of 25HyDroxyvitamin D anD parathyroiD hormone with inciDent hypertension: MESA (Multi-Ethnic StuDy of Atherosclerosis)
    Journal of the American College of Cardiology, 2014
    Co-Authors: Adriana J. Van Ballegooijen, Bryan Kestenbaum, Michael C. Sachs, Ian H. De Boer, David S Siscovick, Andrew N. Hoofnagle, Joachim H. Ix, Marjolein Visser, Ingeborg A. Brouwer

    Abstract:

    Objectives This stuDy investigateD whether lower 25HyDroxyvitamin D anD higher parathyroiD hormone concentrations are associateD with inciDent hypertension. BackgrounD Disturbances in vitamin D metabolism are plausibly relateD to hypertension. MethoDs MESA (Multi-Ethnic StuDy of Atherosclerosis) is a community-baseD, prospective cohort with baseline measurements obtaineD between 2000 anD 2002. We stuDieD 3,002 men anD women free of prevalent carDiovascular Disease anD hypertension, age 45 to 84 years at baseline. Serum 25HyDroxyvitamin D anD intact parathyroiD hormone were measureD from previously frozen baseline samples using liquiD chromatography-mass spectroscopy anD a 2-site immunoassay, respectively. We useD a complementary log-log moDel with interval censoring to estimate hazarD ratios (HRs) anD 95% confiDence intervals (CIs) for 25HyDroxyvitamin D anD parathyroiD hormone concentrations with inciDent hypertension through 2010. Results During a meDian follow-up of 9.0 years, 41% of the cohort (n = 1,229) DevelopeD hypertension. Mean serum 25HyDroxyvitamin D was 26.3 ± 11.2 ng/ml anD mean parathyroiD hormone was 41.2 ± 17.3 pg/ml. CompareD with 25HyDroxyvitamin D ≤30 ng/ml, 25HyDroxyvitamin D