The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Ni Nyoman Tri Puspaningsih - One of the best experts on this subject based on the ideXlab platform.
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
Hery Suwito - One of the best experts on this subject based on the ideXlab platform.
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
Guobao Xu - One of the best experts on this subject based on the ideXlab platform.
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facile surfactant free synthesis and characterization of fe3o4 3 aminophenol formaldehyde core shell magnetic microspheres
Journal of Materials Chemistry, 2015Co-Authors: Jianming Zhao, Rafael Luque, Wenjing Qi, Muhammad Rehan Hasan Shah Gilani, Guobao XuAbstract:Fe3O4@3-Aminophenol–formaldehyde (Fe3O4@APF) core–shell resin polymer magnetic nanocomposites were synthesized using a straightforward surfactant-free methodology. The shell quickly formed within 5 min and could be easily size tunable in the range from 15 to 137 nm by changing the concentrations of 3-Aminophenol and formaldehyde. The morphology, composition and magnetic properties of the resulting magnetic microspheres were characterized by scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and thermogravimetric analysis measurements. The magnetic microspheres were uniform in morphology and can be converted into Fe3O4@carbon magnetic nanocomposites because of their excellent thermal stability. Moreover, Fe3O4@APF magnetic microspheres have excelling adsorption properties in the removal of methyl blue.
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a template free and surfactant free method for high yield synthesis of highly monodisperse 3 aminophenol formaldehyde resin and carbon nano microspheres
Macromolecules, 2013Co-Authors: Jianming Zhao, Ling Zhang, Yali Yuan, Saadat Majeed, Saima Anjum, Guobao XuAbstract:A template-free and surfactant-free method for the synthesis of highly monodisperse phenol formaldehyde resin and corresponding carbon nano/microspheres with excellent size tunability has been developed for the first time after investigating a series of phenol derivatives, including 3-methylphenol, 1,3,5-trihydroxybenzene, 2-aminophenol, 3-Aminophenol, and 4-aminophenol. The method is based on the polymerization reaction of 3-Aminophenol and formaldehyde in the mixture solutions of water and ethanol to generate 3-Aminophenol/formaldehyde (APF) resin colloidal spheres. The sizes of APF resin colloidal spheres are tunable in a very broad range from 80 nm up to 2500 nm by changing reaction conditions. The excellent thermal stability of APF resins allows the generation of monodisperse carbon spheres by the pyrolysis of APF resin spheres with high yields. Both APF resin spheres and corresponding carbon spheres are so monodisperse (polydispersity <3%) that can form three-dimensional periodic structures. The method has striking features of excellent monodispersity, very broad size tunability, high yield, smooth sphere surface, and easy preparation. This approach also holds great promise for the large-scale production of resin spheres and carbon spheres.
Toshimichi Fujiwara - One of the best experts on this subject based on the ideXlab platform.
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
Ritsuko Katahira - One of the best experts on this subject based on the ideXlab platform.
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
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design and synthesis of chalcone derivatives as inhibitors of the ferredoxin ferredoxin nadp reductase interaction of plasmodium falciparum pursuing new antimalarial agents
Molecules, 2014Co-Authors: Hery Suwito, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimataariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri PuspaningsihAbstract:Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP + reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 10.94%-50%. The three strongest inhibition activities were shown by (E)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (50%), (E)-1-(4-aminophenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one (38.16%), and (E)-1-(4-aminophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (31.58%). From the docking experiments we established that the amino group of the methoxyamino chlacone derivatives plays an important role in the inhibition activity by electrostatic interaction
