Absorbable Gelatin Sponge

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Li Na - One of the best experts on this subject based on the ideXlab platform.

  • contrastive analysis of oxidated regenerated cellulose and Absorbable Gelatin Sponge on the hemostasis during acdf procedure
    Shandong Medical Journal, 2014
    Co-Authors: Li Na
    Abstract:

    Objective To compare the hemostatic effect between oxidated regenerated cellulose( ORC) and Absorbable Gelatin Sponge( AGS) during anterior cervical discectomy and fusion procedure( ACDF). Methods 356 patients underwent the ACDF procedure were divided into ORC group( 191 patients) and AGS group( 165 patients). The operative duration,the volume of blood loss and the volume of drainage between two groups were compared. Results The average operative duration in ORC and AGS groups was( 81. 5 ± 9. 9) min and( 88. 6 ± 10. 8) min( P = 0. 062). The average operative blood loss in ORC and AGS groups was( 55. 3 ± 11. 2) m L and( 69. 4 ± 13. 2) m L( P = 0. 034). The average post-operative drainage in ORC and AGS groups was( 35. 5 ± 13. 5) m L and( 51. 2 ± 16. 8) m L( P = 0. 029). One patient in AGS group underwent exploration due to acute neck hematoma post-operatively. Conclusion Compared with AGS,ORC can obviously decrease the operative blood loss and drainage,increase the safety of operation.

Wang Na - One of the best experts on this subject based on the ideXlab platform.

B R Hopkinson - One of the best experts on this subject based on the ideXlab platform.

  • prevention of lumbar artery endoleaks following endovascular abdominal aortic aneurysm repair with the selective use of Absorbable Gelatin Sponge
    British Journal of Surgery, 1999
    Co-Authors: Stuart R Walker, J Macierewicz, B R Hopkinson
    Abstract:

    Background: The aim of endovascular repair of an abdominal aortic aneurysm is to exclude the aneurysm from the systemic circulation in order to prevent aneurysm expansion and rupture. Lumbar artery (LA) endoleaks have been associated with continued expansion of the aneurysm sac and occur with a reported incidence of approximately 10 per cent. The aim of this study was to reduce the incidence of LA or inferior mesenteric artery (IMA) endoleaks. Methods: Following deployment of an aortic uni-iliac graft an aneurysmograph was performed by injecting contrast into the aneurysm sac to look for patent aortic side branches. Patients with no visible side branches had an occluder deployed in the contralateral iliac artery. Patients with patent side branches had an Absorbable Gelatin Sponge inserted into the aneurysm sac before occluder deployment. Patients had contrast-enhanced spiral computed tomography (CT) during follow-up at 1 week, and 3, 6 and 12 months. Results: Fifty-four patients were studied. Eleven were excluded (two perioperative deaths, seven top endoleaks and two occluder endoleaks). Median follow-up was 2 (range 11–7) months. Of the 17 patients in whom patent vessels were demonstrated on an aneurysmograph, one had a patent IMA only, three had a patent LA and IMA, and the remainder had a patent LA. No patient within the study has had a LA or IMA endoleak identified at follow-up CT. Conclusion: An intraoperative aneurysmograph can help select patients for aneurysm sac packing with Gelatin Sponge and has been successful in the short term in preventing LA and IMA endoleaks. © 1999 British Journal of Surgery Society Ltd

Kitti Jirarattanaphochai - One of the best experts on this subject based on the ideXlab platform.

  • prevention of peridural fibrosis using a cyclooxygenase 2 inhibitor nonsteroidal anti inflammatory drug soaked in Absorbable Gelatin Sponge an experimental comparative animal model
    Spine, 2013
    Co-Authors: Surachai Saejung, Kitti Jirarattanaphochai
    Abstract:

    Abstract Experimental study. To evaluate the efficacy and safety of peridural parecoxib-soaked Absorbable Gelatin Sponge, and cellulose membrane on peridural fibrosis prevention in an animal model. Postoperative peridural fibrosis is one of the causes of failed back surgery syndrome. Nonsteroidal anti-inflammatory drugs inhibit the inflammatory response, while an Absorbable Gelatin Sponge or cellulose membrane interposes between the dura and the paraspinal muscle to staunch the surgical bleeding. These mechanisms may prevent peridural fibrosis. Forty L5-L6 laminectomized adult Sprague-Dawley rats were randomly allocated into 4 groups. The high parecoxib group received 6 mg of parecoxib soaked into an Absorbable Gelatin Sponge placed over the dura. The low parecoxib group was given 2 mg of parecoxib soaked into an Absorbable Gelatin Sponge. The dura in the cellulose group was covered with a cellulose membrane, while the control group received normal saline drip before surgical wound closure. All rats were killed at 6 weeks for histopathological assessment. The fibroblast density, inflammatory cell density, fibrous adherence, and adverse events were quantified. The obtained results were analyzed statistically. The respective mean fibroblast density in the high parecoxib, low parecoxib, cellulose, and control groups was 217.77 ± 51.76, 317.51 ± 126.92, 321.80 ± 90.94, and 328.48 ± 73.41 cells/mm², while the respective mean inflammatory cell density was 539.65 ± 236.52, 910.17 ± 242.59, 1011.84 ± 239.30, and 1261.78 ± 319.68 cells/mm². The mean fibroblast and inflammatory cell densities of the high parecoxib group were significantly lower than the control. The high parecoxib group also showed statistically less fibrous adherence than low parecoxib, cellulose, and control groups. The high-dose parecoxib-soaked Absorbable Gelatin Sponge can prevent peridural fibrosis without complications. The low-dose parecoxib and cellulose membrane provided no significant benefit vis-a-vis prevention of peridural fibrosis, as adduced from the lack of any statistically significant difference between the test and control rats.

Stuart R Walker - One of the best experts on this subject based on the ideXlab platform.

  • prevention of lumbar artery endoleaks following endovascular abdominal aortic aneurysm repair with the selective use of Absorbable Gelatin Sponge
    British Journal of Surgery, 1999
    Co-Authors: Stuart R Walker, J Macierewicz, B R Hopkinson
    Abstract:

    Background: The aim of endovascular repair of an abdominal aortic aneurysm is to exclude the aneurysm from the systemic circulation in order to prevent aneurysm expansion and rupture. Lumbar artery (LA) endoleaks have been associated with continued expansion of the aneurysm sac and occur with a reported incidence of approximately 10 per cent. The aim of this study was to reduce the incidence of LA or inferior mesenteric artery (IMA) endoleaks. Methods: Following deployment of an aortic uni-iliac graft an aneurysmograph was performed by injecting contrast into the aneurysm sac to look for patent aortic side branches. Patients with no visible side branches had an occluder deployed in the contralateral iliac artery. Patients with patent side branches had an Absorbable Gelatin Sponge inserted into the aneurysm sac before occluder deployment. Patients had contrast-enhanced spiral computed tomography (CT) during follow-up at 1 week, and 3, 6 and 12 months. Results: Fifty-four patients were studied. Eleven were excluded (two perioperative deaths, seven top endoleaks and two occluder endoleaks). Median follow-up was 2 (range 11–7) months. Of the 17 patients in whom patent vessels were demonstrated on an aneurysmograph, one had a patent IMA only, three had a patent LA and IMA, and the remainder had a patent LA. No patient within the study has had a LA or IMA endoleak identified at follow-up CT. Conclusion: An intraoperative aneurysmograph can help select patients for aneurysm sac packing with Gelatin Sponge and has been successful in the short term in preventing LA and IMA endoleaks. © 1999 British Journal of Surgery Society Ltd