Acoustic Neuroma

14,000,000 Leading Edge Experts on the ideXlab platform

Scan Science and Technology

Contact Leading Edge Experts & Companies

Scan Science and Technology

Contact Leading Edge Experts & Companies

The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform

Moises A. Arriaga - One of the best experts on this subject based on the ideXlab platform.

  • hydroxyapatite cement cranioplasty in translabyrinthine Acoustic Neuroma surgery
    Otolaryngology-Head and Neck Surgery, 2002
    Co-Authors: Moises A. Arriaga, Douglas A Chen
    Abstract:

    Objectives: Hydroxyapatite cement cranioplasty (HAC) after translabyrinthine resection of Acoustic Neuroma is a promising new technique for wound reconstruction. This study reviews the efficacy of HAC for the prevention of cerebrospinal fluid (CSF) leakage and the long-term wound outcomes of HAC versus abdominal fat graft (AFG) reconstruction. Methods: This retrospective study of l08 consecutive Acoustic Neuromas operated on by Pittsburgh Ear Associates uses chart review, telephone interview, and mail questionnaire data. Fifty-four patients received AFG dural repair, and 54 patients received HAC. Results: Seven AFG patients (12.5%) had CSF leaks versus 2 (3.7%) of the overall group of 54 HAC patients. However, none (0%) of the 47 HAC patients had CSF leakage with current HAC techniques. HAC also produced significantly less postauricular wound depression and superior cosmetic results in comparison with AFG. Although HAC patients experienced less postoperative discomfort, wound complications requiring medical or surgical intervention were extremely uncommon in both groups. Conclusion: HAC offers significant CSF leakage control and long-term cosmetic and comfort advantages over AFG alone. We recommend HAC as the standard closure technique for translabyrinthine Acoustic Neuroma surgery. (Otolaryngol Head Neck Surg 2002;126:512-7.)

  • facial function in hearing preservation Acoustic Neuroma surgery
    Archives of Otolaryngology-head & Neck Surgery, 2001
    Co-Authors: Moises A. Arriaga, Douglas A Chen
    Abstract:

    Objective To determine if facial function is worse after hearing preservation Acoustic Neuroma surgery (retrosigmoid and middle fossa) than in translabyrinthine surgery. Design Retrospective medical record review. Setting Private neuro-otology subspecialty practice of patients operated on in a tertiary care hospital. Patients This study evaluated 315 consecutive Acoustic Neuroma surgical procedures between April 1989 and July 1998. A total of 209 translabyrinthine procedures and 106 hearing preservation surgical procedures were performed. The hearing preservation procedures were equally divided between retrosigmoid (n = 48) and middle fossa (n = 58) procedures. Methods Medical records were reviewed and tabulated for tumor size, surgical approach, and House-Brackmann facial function grade at short-, intermediate-, and long-term intervals. Results Postoperative facial function in hearing preservation surgical procedures at short- and long-term follow-up was not worse than facial function after translabyrinthine surgical procedures in comparably sized tumors. Conclusion Concern about postoperative facial function should not be the deciding factor in selecting hearing preservation vs nonhearing preservation Acoustic Neuroma surgery.

  • predicting long term facial nerve outcome after Acoustic Neuroma surgery
    Otolaryngology-Head and Neck Surgery, 1993
    Co-Authors: Moises A. Arriaga, William M. Luxford, James S Atkins, Jed A Kwartler
    Abstract:

    Although anatomic preservation of the facial nerve is achieved in nearly 90% of reported cases after Acoustic Neuroma surgery, postoperative long-term facial function is of most concern to the patient. This study examines long-term facial nerve function in relation to the immediate postoperative function and the function at time of discharge from the hospital. Subjects included 515 patients who underwent primary Acoustic Neuroma removal at House Ear Clinic from 1982 through 1989 and who had normal preoperative facial function, an intact facial nerve after surgery, and a House-Brackmann facial nerve grade available immediately postoperatively, at time of hospital discharge, and at least 1 year postoperatively. Rate of acceptable facial function (House grades I-IV) differed significantly (p < or = 0.001) at the three postoperative time intervals: 85.2%, immediate; 73.6%, discharge; 93.8%, long-term. Of those with good immediate function (grades I-II), 98.6% had acceptable long-term function. Of those with poor immediate function (grades V-VI), 69.8% had acceptable long-term function. We conclude that facial nerve recovery after Acoustic Neuroma surgery is characterized by slight deterioration in the immediate postoperative period, but subsequent improvement in the long-term. Patients can be reliably counseled that acceptable function immediately after surgery is associated with a favorable long-term outcome; poor function immediately after surgery, despite an intact nerve, has a more guarded prognosis.

  • Clinical correlates of Acoustic Neuroma volume.
    The American journal of otology, 1993
    Co-Authors: Moises A. Arriaga, Steven A. Long, Ralph A. Nelson
    Abstract:

    A computer-assisted, MRI-based technique of tumor volume determination was used to correlate preoperative hearing levels and long-term postoperative facial function with Acoustic Neuroma volume. Preoperative hearing was studied in a group of 41 patients subjected to direct tumor volume calculations and in another group of 131 patients in whom volume was extrapolated from the Acoustic Neuroma volume-diameter relation. Similarly postoperative facial function was correlated with Acoustic Neuroma volume in another 864 patients in whom long-term follow-up was available. Preoperative hearing levels were found not to be significantly related to tumor volume

Maria Feychting - One of the best experts on this subject based on the ideXlab platform.

  • Occupational exposures and risk of Acoustic Neuroma.
    Occupational and environmental medicine, 2010
    Co-Authors: Michaela Prochazka, Colin G Edwards, Gun Nise, Anders Ahlbom, Maria Feychting, Judith A Schwartzbaum, Nils Plato, Ulla M Forssen
    Abstract:

    Acoustic Neuroma is a benign tumour accounting for approximately 6-10% of all intracranial tumours and occurs mainly in patients aged ≥50 years. Our aim was to investigate a wide range of occupational exposures, individual occupational titles and socioeconomic status (SES) as potential risk factors for Acoustic Neuroma. We conducted a population-based case-control study of 793 Acoustic Neuroma cases identified through the Swedish Cancer Registry and 101,762 randomly selected controls. Information on SES and occupation was obtained from censuses and linked to job-exposure matrices. Logistic regression was used to estimate ORs and calculate 95% CIs. An increased OR was seen for mercury exposure <10 years before the reference year (OR 2.9; 95% CI 1.2 to 6.8), and a more modest association for benzene exposure (OR 1.8; 95% CI: 1.0 to 3.2) ≥10 years before the reference year. We observed a threefold increased risk for females working as tailors and dressmakers ≥10 years before the reference year, and a more than threefold significantly elevated OR for those working as truck and conveyor operators <10 years before the reference year. We found no convincing evidence that SES is related to disease development. We observed an increased risk of Acoustic Neuroma associated with occupational exposure to mercury, benzene and textile dust. Men working as truck and conveyor operators <10 years before the reference year had the highest increased risk of Acoustic Neuroma, but it is unclear what in those occupations might contribute to disease development. Our study also suggested an association between Acoustic Neuroma and being a class teacher or policeman. However, these findings should be further investigated to exclude the possibility of detection bias.

  • occupational noise exposure and risk of Acoustic Neuroma
    American Journal of Epidemiology, 2007
    Co-Authors: Colin G Edwards, Gun Nise, Ulla M Forssen, Anders Ahlbom, Stefan Lonn, Judith A Schwartzbaum, Maria Feychting
    Abstract:

    A small number of prior epidemiologic studies of occupational noise exposure based on self-report have suggested an association with Acoustic Neuroma. The goal of the present study was to further examine the association between noise exposure and Acoustic Neuroma by using an objective measure of exposure in the form of a job exposure matrix. A total of 793 Acoustic Neuroma cases aged 21–84 years were identified between 1987 and 1999 from the Swedish Cancer Registry. The 101,756 controls randomly selected from the study base were frequency matched to cases on age, sex, and calendar year of diagnosis. Occupational information, available for 599 of the cases and 73,432 of the controls, was obtained from censuses and was linked to a job exposure matrix based on actual noise measurements. All risk estimates were close to unity, regardless of noise exposure level or parameter. The overall odds ratio for exposure to � 85 dB of noise was 0.89 (95% confidence interval: 0.64, 1.23). Contrary to previous study results, the present findings did not demonstrate an increased Acoustic Neuroma risk related to occupational noise exposure even after allowing for a long latency period. The effect of nondifferential misclassification of exposure must be considered a potential cause of the negative findings. case-control studies; Neuroma, Acoustic; noise; risk factors

  • medical history cigarette smoking and risk of Acoustic Neuroma an international case control study
    International Journal of Cancer, 2007
    Co-Authors: Minouk J Schoemaker, Maria Feychting, Helle Collatz Christensen, Christoffer Johansen, Anthony J Swerdlow, Anssi Auvinen, Lars Klaeboe, Sigrid Lonn, Tiina Salminen
    Abstract:

    Acoustic Neuroma (vestibular schwannoma) is a benign tumor of the vestibulocochlear nerve. Its recorded incidence is increasing but risk factors for this tumor have scarcely been investigated. We conducted a population-based case-control study of risk factors for Acoustic Neuroma in the UK and Nordic countries, including 563 cases and 2,703 controls. Tumor risk was analyzed in relation to medical history and cigarette smoking. Risk of Acoustic Neuroma was significantly raised in parous compared with nulliparous women (OR = 1.7, 95% CI: 1.1-2.6), but was not related to age at first birth or number of children. Risk was not associated with a history of allergic disease, past head injury, past diagnosis of a neoplasm or birth characteristics, but was significantly raised for past diagnosis of epilepsy (OR = 2.5, 95% CI: 1.3-4.9). Tumor risk was significantly reduced in subjects who had ever regularly smoked cigarettes (OR = 0.7, 95% CI: 0.6-0.9), but the reduction applied only to current smokers (OR = 0.5, 95% CI: 0.4-0.6), not ex-smokers (OR = 1.0, 95% CI: 0.8-1.3). The reduced risk of Acoustic Neuroma in smokers and raised risk in parous women might relate to sex hormone levels, or smoking might suppress tumor growth, but effects of parity and smoking on timing of diagnosis of the tumor are also a potential explanation. The raised risk in relation to past diagnosis of epilepsy might be a surveillance artefact or imply that epilepsy and/or antiepileptic medication use predispose to Acoustic Neuroma. These findings need replication by other studies and possible mechanisms need to be clarified.

  • Exposure to Loud Noise and Risk of Acoustic Neuroma
    American journal of epidemiology, 2005
    Co-Authors: Colin G Edwards, Anders Ahlbom, Stefan Lonn, Judith A Schwartzbaum, Maria Feychting
    Abstract:

    Exposure to occupational loud noise has been previously identified as a possible risk factor for Acoustic Neuroma in only one relatively small (n = 86 cases) case-control study of men. The goal of the present study was to further examine the role of loud noise in Acoustic Neuroma etiology. In their population-based case-control study of both sexes conducted from 1999 to 2002 in Sweden, the authors compared reports on type and duration of occupational and nonoccupational loud noise exposure of 146 Acoustic Neuroma cases and 564 controls. Controls were randomly selected from the study base and were frequency matched on age, sex, and residential area. The authors found that individuals reporting loud noise exposure from any source were at increased risk for Acoustic Neuroma (odds ratio (OR) = 1.55, 95% confidence interval (CI): 1.04, 2.30). Exposure to loud noise from machines, power tools, and/or construction increased the risk for Acoustic Neuroma (OR = 1.79, 95% CI: 1.11, 2.89), as did exposure to loud music (OR = 2.25, 95% CI: 1.20, 4.23). The odds ratio for a latency period of 13 or more years since the first loud noise exposure from any source was 2.12 (95% CI: 1.40, 3.20). The findings of an increased risk of Acoustic Neuroma with loud noise exposure support previous research.

  • mobile phone use and risk of Acoustic Neuroma results of the interphone case control study in five north european countries
    British Journal of Cancer, 2005
    Co-Authors: Minouk J Schoemaker, Anders Ahlbom, Maria Feychting, Anthony J Swerdlow, Anssi Auvinen, K G Blaasaas, Elisabeth Cardis, Collatz H Christensen, S J Hepworth
    Abstract:

    There is public concern that use of mobile phones could increase the risk of brain tumours. If such an effect exists, Acoustic Neuroma would be of particular concern because of the proximity of the Acoustic nerve to the handset. We conducted, to a shared protocol, six population-based case–control studies in four Nordic countries and the UK to assess the risk of Acoustic Neuroma in relation to mobile phone use. Data were collected by personal interview from 678 cases of Acoustic Neuroma and 3553 controls. The risk of Acoustic Neuroma in relation to regular mobile phone use in the pooled data set was not raised (odds ratio (OR)=0.9, 95% confidence interval (CI): 0.7–1.1). There was no association of risk with duration of use, lifetime cumulative hours of use or number of calls, for phone use overall or for analogue or digital phones separately. Risk of a tumour on the same side of the head as reported phone use was raised for use for 10 years or longer (OR=1.8, 95% CI: 1.1–3.1). The study suggests that there is no substantial risk of Acoustic Neuroma in the first decade after starting mobile phone use. However, an increase in risk after longer term use or after a longer lag period could not be ruled out.

Joachim Schuz - One of the best experts on this subject based on the ideXlab platform.

  • environmental risk factors for sporadic Acoustic Neuroma interphone study group germany
    European Journal of Cancer, 2007
    Co-Authors: Brigitte Schlehofer, Klaus Schlaefer, Maria Blettner, Gabriele Berg, Eva Bohler, I Hettinger, K Kunnagrass, Jurgen Wahrendorf, Joachim Schuz
    Abstract:

    The only known risk factor for sporadic Acoustic Neuroma is high-dose ionising radiation. Environmental exposures, such as radiofrequency electromagnetic fields and noise are under discussion, as well as an association with allergic diseases. We performed a population-based case-control study in Germany investigating these risk factors in 97 cases with Acoustic Neuroma, aged 30 to 69 years, and in 194 matched controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in multiple logistic regression models. Increased risks were found for exposure to persistent noise (OR=2.31; 95% CI 1.15-4.66), and for hay fever (OR=2.20; 95% CI 1.09-4.45), but not for ionising radiation (OR=0.91; 95 % CI 0.51-1.61) or regular mobile phone use (OR=0.67; 95% CI 0.38-1.19). The study confirms results of recently published studies, although the pathogenetic mechanisms are still unknown.

  • cellular telephone use and risk of Acoustic Neuroma
    American Journal of Epidemiology, 2004
    Co-Authors: Helle Collatz Christensen, J. Thomsen, Joachim Schuz, Michael Kosteljanetz, Hans Skovgaard Poulsen, Christoffer Johansen
    Abstract:

    Despite limited evidence, cellular telephones have been claimed to cause cancer, especially in the brain. In this Danish study, the authors examined the possible association between use of cellular telephones and development of Acoustic Neuroma. Between 2000 and 2002, they ascertained 106 incident cases and matched these persons with 212 randomly sampled, population-based controls on age and sex. The data obtained included information on use of cellular telephones from personal interviews, data from medical records, and the results of radiologic examinations. The authors obtained information on socioeconomic factors from Statistics Denmark. The overall estimated relative risk of Acoustic Neuroma was 0.90 (95% confidence interval: 0.51, 1.57). Use of a cell phone for 10 years or more did not increase Acoustic Neuroma risk over that of short-term users. Furthermore, tumors did not occur more frequently on the side of the head on which the telephone was typically used, and the size of the tumor did not correlate with the pattern of cell phone use. The results of this prospective, population-based, nationwide study, which included a large number of long-term users of cellular telephones, do not support an association between cell phone use and risk of Acoustic Neuroma.

Steven W Cheung - One of the best experts on this subject based on the ideXlab platform.

  • tinnitus following treatment for sporadic Acoustic Neuroma
    Laryngoscope, 2016
    Co-Authors: Jonathan B Overdevest, Seth E Pross, Steven W Cheung
    Abstract:

    Objectives/Hypothesis To evaluate the impact of treatment modality, tumor size, time from therapy, and demographic features on tinnitus distress, as measured by the Tinnitus Functional Index (TFI) in patients treated for sporadic Acoustic Neuroma. Study Design Cross-sectional observation study. Methods A Web-based 44-question online survey was made available on the Acoustic Neuroma Association Web site for 3 months. Of 154 unique surveys that were completed in entirety, further screening netted 143 study participants. Questions included the TFI, treatment modality, tumor size, time from therapy, demographic features, and hearing status of both ears. Results Tinnitus distress following treatment for Acoustic Neuroma is independent of treatment type, tumor size, tumor laterality, time after treatment, age, and gender. Tinnitus Functional Index scores closely mirror severity profile of the study population as reported in the pivotal TFI instrument validation study by Meikle et al.17 Tinnitus is “not a problem” in 20% of respondents, a “small problem” in 20%, a “moderate problem” in 11%, a “big problem” in 22%, and a “very big problem” in 27%. Subscale analysis suggests that Acoustic tumor patients struggle most with tinnitus intrusiveness and loss of control. Conclusions Whereas tinnitus is a common symptom in Acoustic Neuroma patients in both the pre- and posttreatment settings, clinicians can provide counsel that choice of treatment modality, tumor size, age, and gender have little to no bearing on severity of posttreatment tinnitus distress. Tinnitus severity does not differ among the treatment choices of open microsurgery, stereotactic radiosurgery, external beam radiation, and observation. Level of Evidence NA Laryngoscope, 2015

William M. Luxford - One of the best experts on this subject based on the ideXlab platform.

  • Sudden hearing loss in Acoustic Neuroma patients
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995
    Co-Authors: James E. Saunders, William M. Luxford, K. Kay Devgan, Bruce L. Fetterman
    Abstract:

    Patients with Acoustic Neuroma may have sudden sensorineural hearing loss. Most patients with sudden hearing loss seek medical attention promptly, but the diagnosis of an Acoustic Neuroma may be delayed for months or years because sudden hearing loss is an unusual initial symptom of an Acoustic Neuroma. In a retrospective review of 836 cases of sudden hearing loss, we found 13 patients with Acoustic Neuromas. The prevalence of Acoustic Neuromas for those screened with auditory brain stem response or magnetic resonance imaging was 2.5%. In addition to these 13 patients, 79 Acoustic Neuroma patients treated in our clinic had well-documented sudden hearing loss as the initial symptom. Hearing loss in these 92 patients ranged from mild to profound. Associated symptoms of pain, facial paresthesia, or unilateral tinnitus preceding the sudden hearing loss were suggestive of an Acoustic Neuroma, as was a midfrequency (U-shaped) hearing loss. A history of other diseases or events that might explain the sudden hearing loss, a normal electronystagmogram, or recovery of hearing does not eliminate the possibility of a tumor. Because there are no clinical findings that clearly distinguish those patients with Acoustic Neuromas from other patients with sudden hearing loss, we recommend either an evaluation with auditory brain stem response or gadolinium-enhanced magnetic resonance imaging for any patient with sudden hearing loss.

  • Acoustic Neuroma in pregnancy.
    The American journal of otology, 1994
    Co-Authors: William M. Luxford
    Abstract:

    Acoustic Neuroma in the pregnant patient has been described infrequently. The symptoms of Acoustic Neuroma can commence or worsen during the last 3 or 4 months of pregnancy. In women, Acoustic tumors have been shown generally to be larger and more vascular, and some Acoustic tumors contain estrogen receptors. This is a report of our management of two patients with Acoustic Neuroma who presented early in pregnancy. Surgery was delayed to the second trimester in each, to avoid spontaneous abortion. Both patients underwent translabyrinthine tumor removal at 18-19 weeks gestation, and each had an uncomplicated postoperative course. Examination of the tumor for estrogen receptors was performed for the second patient and was negative. Uncomplicated Acoustic Neuroma surgery can be performed in pregnant patients during the second trimester.

  • predicting long term facial nerve outcome after Acoustic Neuroma surgery
    Otolaryngology-Head and Neck Surgery, 1993
    Co-Authors: Moises A. Arriaga, William M. Luxford, James S Atkins, Jed A Kwartler
    Abstract:

    Although anatomic preservation of the facial nerve is achieved in nearly 90% of reported cases after Acoustic Neuroma surgery, postoperative long-term facial function is of most concern to the patient. This study examines long-term facial nerve function in relation to the immediate postoperative function and the function at time of discharge from the hospital. Subjects included 515 patients who underwent primary Acoustic Neuroma removal at House Ear Clinic from 1982 through 1989 and who had normal preoperative facial function, an intact facial nerve after surgery, and a House-Brackmann facial nerve grade available immediately postoperatively, at time of hospital discharge, and at least 1 year postoperatively. Rate of acceptable facial function (House grades I-IV) differed significantly (p < or = 0.001) at the three postoperative time intervals: 85.2%, immediate; 73.6%, discharge; 93.8%, long-term. Of those with good immediate function (grades I-II), 98.6% had acceptable long-term function. Of those with poor immediate function (grades V-VI), 69.8% had acceptable long-term function. We conclude that facial nerve recovery after Acoustic Neuroma surgery is characterized by slight deterioration in the immediate postoperative period, but subsequent improvement in the long-term. Patients can be reliably counseled that acceptable function immediately after surgery is associated with a favorable long-term outcome; poor function immediately after surgery, despite an intact nerve, has a more guarded prognosis.