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Acquired Immunodeficiency Syndrome

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Narsing A. Rao – One of the best experts on this subject based on the ideXlab platform.

Mary Fran Mclane – One of the best experts on this subject based on the ideXlab platform.

Janusz Gill – One of the best experts on this subject based on the ideXlab platform.

  • Primary lymphoma of the kidney in the Acquired Immunodeficiency Syndrome.
    Archives of pathology & laboratory medicine, 1993
    Co-Authors: Tsang K, Kneafsey P, Janusz Gill
    Abstract:

    An increased incidence of lymphoma has been reported in patients with the Acquired Immunodeficiency Syndrome. Malignant lymphomas that develop within this setting of impaired immune surveillance have distinctive clinical, histologic, and molecular biologic characteristics. Histologically, the majority of these lymphomas are small noncleaved cell or immunoblastic lymphomas, and are B-cell phenotype by immunophenotypic and immunoglobulin gene rearrangement studies. In contrast with malignant lymphoma occurring in the general population, extranodal origin is common in Acquired Immunodeficiency Syndrome-related non-Hodgkin’s lymphomas, with the central nervous system, bone marrow, gastrointestinal tract, and liver being the most common sites. To the best of our knowledge, there has been no description in the literature of primary renal lymphoma occurring in patients with the Acquired Immunodeficiency Syndrome. We report an unusual case of primary non-Hodgkin’s lymphoma (diffuse B-cell immunoblastic type) of the kidney in a patient with the Acquired Immunodeficiency Syndrome.

George T. Frangieh – One of the best experts on this subject based on the ideXlab platform.

  • Ocular manifestations of Acquired Immunodeficiency Syndrome
    Current Opinion in Ophthalmology, 1992
    Co-Authors: George T. Frangieh, Pravin U. Dugel, Narsing A. Rao
    Abstract:

    Ocular manifestations of Acquired Immunodeficiency Syndrome may be seen in up to 75 of patients. A wide range of ocular pathology occurs in Acquired Immunodeficiency Syndrome patients. Most common are cotton-wool spots, retinal hemorrhages, cytomegalovirus retinitis, and ocular Kaposi’s sarcoma, followed much less frequently by herpes zoster ophthalmicus, retinal toxoplasmosis, cryptococcus infections, and herpes simplex retinitis. Rare posterior segment choroidal manifestations include Pneumocystis carinii choroiditis, atypical mycobacterial choroiditis, and Histoplasma capsulatum chorioretinitis. Other manifestations include Roth spots, papilledema, perivasculitis, and optic nerve affection by cytomegalovirus and cryptococcus infection. Rare anterior segment manifestations include molluscum contagiosum lid lesions, keratitis sicca, and fungal and herpetic corneal ulcers. In light of the high incidence of ocular lesions in Acquired Immunodeficiency Syndrome patients, and the improving ability to treat infections and neoplastic lesions, it is essential that ophthalmologists be thoroughly familiar with the ocular lesions seen in these patients.

Craig M Greven – One of the best experts on this subject based on the ideXlab platform.