The Experts below are selected from a list of 423 Experts worldwide ranked by ideXlab platform
Rhonda L Cornum - One of the best experts on this subject based on the ideXlab platform.
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treatment of grade 4 renal stab wounds with absorbable fibrin Adhesive Bandage in a porcine model
2001Co-Authors: Allen F Morey, John G Anema, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Martin Macphee, Rhonda L CornumAbstract:Purpose: In a porcine model we evaluated the efficacy of the absorbable fibrin Adhesive Bandage and other novel fibrin products for treating major renal stab wounds.Materials and Methods: In commercial swine we produced an almost lethal, grade 4 renal stab wound via a 3.5 cm. sagittal, centrally located, through-and-through laceration. Each pig then received treatment in random fashion, including conventional oversewing of capsular defects with absorbable gelatin sponge and horizontal mattress sutures in 6, external absorbable fibrin Adhesive Bandage that was pressure held for 60 seconds in 6, external and internal absorbable fibrin Adhesive Bandage that was applied externally, inserted into the renal defect and pressure held for 60 seconds in 6, liquid fibrin sealant that was placed in the laceration and held for 60 seconds in 8, fibrin foam that was applied in the same manner as liquid fibrin in 5 and closing of the peritoneum over the lacerated kidney without further treatment in 6. Blood loss and time...
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does the absorbable fibrin Adhesive Bandage facilitate partial nephrectomy
2000Co-Authors: Rhonda L Cornum, Allen F Morey, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Anthony E Pusateri, John B Holcomb, Martin MacpheeAbstract:Purpose: To evaluate the ability of the absorbable fibrin Adhesive Bandage (AFAB), a prototype product comprising lyophilized fibrinogen and thrombin on a VicrylTM mesh backing, to seal the collecting system and control bleeding after partial nephrectomy.Materials and Methods: Growing female pigs (n = 18) underwent left nephrectomy and a 40% (by length) right lower pole partial nephrectomy. One of three treatments was immediately applied: Conventional–closure of the collecting system, ligation of visible segmental vessels, application of SurgicelTM with bolstering sutures to the renal capsule; AFAB–application of up to two 4 × 4-inch AFABs held under pressure for 60 seconds; Placebo–application of a hemostatically inert VicrylTM Bandage, visually identical to the AFAB. Blood loss and ischemic and total operative times were recorded, and abdominal computerized tomography (CT) was performed on postoperative day 6. Animals were sacrificed at 6 weeks to evaluate the remaining renal mass histologically.Results...
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intraoperative use of the absorbable fibrin Adhesive Bandage long term effects
1999Co-Authors: Rhonda L Cornum, Vincent Gresham, Dawson Beall, James Bell, William W Brinkley, Martin MacpheeAbstract:Purpose:: The absorbable fibrin Adhesive Bandage (AFAB) reduces acute blood loss in experimental trauma models, but the effects on wound healing and subsequent function have heretofore not been investigated. Retropubic prostatectomy was selected to evaluate short and long term effects of using the AFAB intraoperatively.Materials and Methods:: Dogs undergoing prostatectomy were randomly assigned to one of four treatments: CONTROL- sponges and manual pressure were applied after transecting the prostatic pedicles. Sponges were removed when the prostate was delivered. Vessels were isolated and ligated if bleeding continued after removal. AFAB- hemostatically active Bandages were applied to the prostatic bed prior to sponges and pressure. Additional Bandages were applied at the urethrovesical junction after completing the anastomosis. PLACEBO- visually identical (hemostatically inert) Bandages were applied in an identical fashion. LIQUID SEALANT- concentrated thrombin and fibrinogen solution was applied to the...
Martin Macphee - One of the best experts on this subject based on the ideXlab platform.
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treatment of grade 4 renal stab wounds with absorbable fibrin Adhesive Bandage in a porcine model
2001Co-Authors: Allen F Morey, John G Anema, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Martin Macphee, Rhonda L CornumAbstract:Purpose: In a porcine model we evaluated the efficacy of the absorbable fibrin Adhesive Bandage and other novel fibrin products for treating major renal stab wounds.Materials and Methods: In commercial swine we produced an almost lethal, grade 4 renal stab wound via a 3.5 cm. sagittal, centrally located, through-and-through laceration. Each pig then received treatment in random fashion, including conventional oversewing of capsular defects with absorbable gelatin sponge and horizontal mattress sutures in 6, external absorbable fibrin Adhesive Bandage that was pressure held for 60 seconds in 6, external and internal absorbable fibrin Adhesive Bandage that was applied externally, inserted into the renal defect and pressure held for 60 seconds in 6, liquid fibrin sealant that was placed in the laceration and held for 60 seconds in 8, fibrin foam that was applied in the same manner as liquid fibrin in 5 and closing of the peritoneum over the lacerated kidney without further treatment in 6. Blood loss and time...
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does the absorbable fibrin Adhesive Bandage facilitate partial nephrectomy
2000Co-Authors: Rhonda L Cornum, Allen F Morey, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Anthony E Pusateri, John B Holcomb, Martin MacpheeAbstract:Purpose: To evaluate the ability of the absorbable fibrin Adhesive Bandage (AFAB), a prototype product comprising lyophilized fibrinogen and thrombin on a VicrylTM mesh backing, to seal the collecting system and control bleeding after partial nephrectomy.Materials and Methods: Growing female pigs (n = 18) underwent left nephrectomy and a 40% (by length) right lower pole partial nephrectomy. One of three treatments was immediately applied: Conventional–closure of the collecting system, ligation of visible segmental vessels, application of SurgicelTM with bolstering sutures to the renal capsule; AFAB–application of up to two 4 × 4-inch AFABs held under pressure for 60 seconds; Placebo–application of a hemostatically inert VicrylTM Bandage, visually identical to the AFAB. Blood loss and ischemic and total operative times were recorded, and abdominal computerized tomography (CT) was performed on postoperative day 6. Animals were sacrificed at 6 weeks to evaluate the remaining renal mass histologically.Results...
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intraoperative use of the absorbable fibrin Adhesive Bandage long term effects
1999Co-Authors: Rhonda L Cornum, Vincent Gresham, Dawson Beall, James Bell, William W Brinkley, Martin MacpheeAbstract:Purpose:: The absorbable fibrin Adhesive Bandage (AFAB) reduces acute blood loss in experimental trauma models, but the effects on wound healing and subsequent function have heretofore not been investigated. Retropubic prostatectomy was selected to evaluate short and long term effects of using the AFAB intraoperatively.Materials and Methods:: Dogs undergoing prostatectomy were randomly assigned to one of four treatments: CONTROL- sponges and manual pressure were applied after transecting the prostatic pedicles. Sponges were removed when the prostate was delivered. Vessels were isolated and ligated if bleeding continued after removal. AFAB- hemostatically active Bandages were applied to the prostatic bed prior to sponges and pressure. Additional Bandages were applied at the urethrovesical junction after completing the anastomosis. PLACEBO- visually identical (hemostatically inert) Bandages were applied in an identical fashion. LIQUID SEALANT- concentrated thrombin and fibrinogen solution was applied to the...
Vincent Gresham - One of the best experts on this subject based on the ideXlab platform.
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treatment of grade 4 renal stab wounds with absorbable fibrin Adhesive Bandage in a porcine model
2001Co-Authors: Allen F Morey, John G Anema, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Martin Macphee, Rhonda L CornumAbstract:Purpose: In a porcine model we evaluated the efficacy of the absorbable fibrin Adhesive Bandage and other novel fibrin products for treating major renal stab wounds.Materials and Methods: In commercial swine we produced an almost lethal, grade 4 renal stab wound via a 3.5 cm. sagittal, centrally located, through-and-through laceration. Each pig then received treatment in random fashion, including conventional oversewing of capsular defects with absorbable gelatin sponge and horizontal mattress sutures in 6, external absorbable fibrin Adhesive Bandage that was pressure held for 60 seconds in 6, external and internal absorbable fibrin Adhesive Bandage that was applied externally, inserted into the renal defect and pressure held for 60 seconds in 6, liquid fibrin sealant that was placed in the laceration and held for 60 seconds in 8, fibrin foam that was applied in the same manner as liquid fibrin in 5 and closing of the peritoneum over the lacerated kidney without further treatment in 6. Blood loss and time...
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does the absorbable fibrin Adhesive Bandage facilitate partial nephrectomy
2000Co-Authors: Rhonda L Cornum, Allen F Morey, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Anthony E Pusateri, John B Holcomb, Martin MacpheeAbstract:Purpose: To evaluate the ability of the absorbable fibrin Adhesive Bandage (AFAB), a prototype product comprising lyophilized fibrinogen and thrombin on a VicrylTM mesh backing, to seal the collecting system and control bleeding after partial nephrectomy.Materials and Methods: Growing female pigs (n = 18) underwent left nephrectomy and a 40% (by length) right lower pole partial nephrectomy. One of three treatments was immediately applied: Conventional–closure of the collecting system, ligation of visible segmental vessels, application of SurgicelTM with bolstering sutures to the renal capsule; AFAB–application of up to two 4 × 4-inch AFABs held under pressure for 60 seconds; Placebo–application of a hemostatically inert VicrylTM Bandage, visually identical to the AFAB. Blood loss and ischemic and total operative times were recorded, and abdominal computerized tomography (CT) was performed on postoperative day 6. Animals were sacrificed at 6 weeks to evaluate the remaining renal mass histologically.Results...
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intraoperative use of the absorbable fibrin Adhesive Bandage long term effects
1999Co-Authors: Rhonda L Cornum, Vincent Gresham, Dawson Beall, James Bell, William W Brinkley, Martin MacpheeAbstract:Purpose:: The absorbable fibrin Adhesive Bandage (AFAB) reduces acute blood loss in experimental trauma models, but the effects on wound healing and subsequent function have heretofore not been investigated. Retropubic prostatectomy was selected to evaluate short and long term effects of using the AFAB intraoperatively.Materials and Methods:: Dogs undergoing prostatectomy were randomly assigned to one of four treatments: CONTROL- sponges and manual pressure were applied after transecting the prostatic pedicles. Sponges were removed when the prostate was delivered. Vessels were isolated and ligated if bleeding continued after removal. AFAB- hemostatically active Bandages were applied to the prostatic bed prior to sponges and pressure. Additional Bandages were applied at the urethrovesical junction after completing the anastomosis. PLACEBO- visually identical (hemostatically inert) Bandages were applied in an identical fashion. LIQUID SEALANT- concentrated thrombin and fibrinogen solution was applied to the...
Dawson Beall - One of the best experts on this subject based on the ideXlab platform.
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treatment of grade 4 renal stab wounds with absorbable fibrin Adhesive Bandage in a porcine model
2001Co-Authors: Allen F Morey, John G Anema, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Martin Macphee, Rhonda L CornumAbstract:Purpose: In a porcine model we evaluated the efficacy of the absorbable fibrin Adhesive Bandage and other novel fibrin products for treating major renal stab wounds.Materials and Methods: In commercial swine we produced an almost lethal, grade 4 renal stab wound via a 3.5 cm. sagittal, centrally located, through-and-through laceration. Each pig then received treatment in random fashion, including conventional oversewing of capsular defects with absorbable gelatin sponge and horizontal mattress sutures in 6, external absorbable fibrin Adhesive Bandage that was pressure held for 60 seconds in 6, external and internal absorbable fibrin Adhesive Bandage that was applied externally, inserted into the renal defect and pressure held for 60 seconds in 6, liquid fibrin sealant that was placed in the laceration and held for 60 seconds in 8, fibrin foam that was applied in the same manner as liquid fibrin in 5 and closing of the peritoneum over the lacerated kidney without further treatment in 6. Blood loss and time...
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does the absorbable fibrin Adhesive Bandage facilitate partial nephrectomy
2000Co-Authors: Rhonda L Cornum, Allen F Morey, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Anthony E Pusateri, John B Holcomb, Martin MacpheeAbstract:Purpose: To evaluate the ability of the absorbable fibrin Adhesive Bandage (AFAB), a prototype product comprising lyophilized fibrinogen and thrombin on a VicrylTM mesh backing, to seal the collecting system and control bleeding after partial nephrectomy.Materials and Methods: Growing female pigs (n = 18) underwent left nephrectomy and a 40% (by length) right lower pole partial nephrectomy. One of three treatments was immediately applied: Conventional–closure of the collecting system, ligation of visible segmental vessels, application of SurgicelTM with bolstering sutures to the renal capsule; AFAB–application of up to two 4 × 4-inch AFABs held under pressure for 60 seconds; Placebo–application of a hemostatically inert VicrylTM Bandage, visually identical to the AFAB. Blood loss and ischemic and total operative times were recorded, and abdominal computerized tomography (CT) was performed on postoperative day 6. Animals were sacrificed at 6 weeks to evaluate the remaining renal mass histologically.Results...
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intraoperative use of the absorbable fibrin Adhesive Bandage long term effects
1999Co-Authors: Rhonda L Cornum, Vincent Gresham, Dawson Beall, James Bell, William W Brinkley, Martin MacpheeAbstract:Purpose:: The absorbable fibrin Adhesive Bandage (AFAB) reduces acute blood loss in experimental trauma models, but the effects on wound healing and subsequent function have heretofore not been investigated. Retropubic prostatectomy was selected to evaluate short and long term effects of using the AFAB intraoperatively.Materials and Methods:: Dogs undergoing prostatectomy were randomly assigned to one of four treatments: CONTROL- sponges and manual pressure were applied after transecting the prostatic pedicles. Sponges were removed when the prostate was delivered. Vessels were isolated and ligated if bleeding continued after removal. AFAB- hemostatically active Bandages were applied to the prostatic bed prior to sponges and pressure. Additional Bandages were applied at the urethrovesical junction after completing the anastomosis. PLACEBO- visually identical (hemostatically inert) Bandages were applied in an identical fashion. LIQUID SEALANT- concentrated thrombin and fibrinogen solution was applied to the...
Allen F Morey - One of the best experts on this subject based on the ideXlab platform.
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treatment of grade 4 renal stab wounds with absorbable fibrin Adhesive Bandage in a porcine model
2001Co-Authors: Allen F Morey, John G Anema, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Martin Macphee, Rhonda L CornumAbstract:Purpose: In a porcine model we evaluated the efficacy of the absorbable fibrin Adhesive Bandage and other novel fibrin products for treating major renal stab wounds.Materials and Methods: In commercial swine we produced an almost lethal, grade 4 renal stab wound via a 3.5 cm. sagittal, centrally located, through-and-through laceration. Each pig then received treatment in random fashion, including conventional oversewing of capsular defects with absorbable gelatin sponge and horizontal mattress sutures in 6, external absorbable fibrin Adhesive Bandage that was pressure held for 60 seconds in 6, external and internal absorbable fibrin Adhesive Bandage that was applied externally, inserted into the renal defect and pressure held for 60 seconds in 6, liquid fibrin sealant that was placed in the laceration and held for 60 seconds in 8, fibrin foam that was applied in the same manner as liquid fibrin in 5 and closing of the peritoneum over the lacerated kidney without further treatment in 6. Blood loss and time...
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does the absorbable fibrin Adhesive Bandage facilitate partial nephrectomy
2000Co-Authors: Rhonda L Cornum, Allen F Morey, Richard G Harris, Vincent Gresham, Rohini Daniels, Ward R Knight, Dawson Beall, Anthony E Pusateri, John B Holcomb, Martin MacpheeAbstract:Purpose: To evaluate the ability of the absorbable fibrin Adhesive Bandage (AFAB), a prototype product comprising lyophilized fibrinogen and thrombin on a VicrylTM mesh backing, to seal the collecting system and control bleeding after partial nephrectomy.Materials and Methods: Growing female pigs (n = 18) underwent left nephrectomy and a 40% (by length) right lower pole partial nephrectomy. One of three treatments was immediately applied: Conventional–closure of the collecting system, ligation of visible segmental vessels, application of SurgicelTM with bolstering sutures to the renal capsule; AFAB–application of up to two 4 × 4-inch AFABs held under pressure for 60 seconds; Placebo–application of a hemostatically inert VicrylTM Bandage, visually identical to the AFAB. Blood loss and ischemic and total operative times were recorded, and abdominal computerized tomography (CT) was performed on postoperative day 6. Animals were sacrificed at 6 weeks to evaluate the remaining renal mass histologically.Results...