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Shu-li You – One of the best experts on this subject based on the ideXlab platform.
Iridium-Catalyzed Asymmetric Allylic Amination Reactions with N-Aryl Phosphoramidite LigandsOrganometallics, 2016Co-Authors: Xiao Zhang, Qiang Cheng, Wen-bo Liu, Shu-li YouAbstract:
A series of N-aryl phosphoramidite ligands were synthesized, and the iridium complexes derived from these novel ligands were proven to be efficient catalysts for asymmetric intermolecular Allylic Amination reactions. This C–N bond forming process readily accommodates a diverse range of amines and Allylic carbonates, especially for the previously challenging ortho-substituted cinnamyl substrates. Moreover, isolation and characterization of the corresponding (π-allyl)–iridium complex K1 reveal that the active iridacycle is generated through a C(sp2)–H bond insertion of tetrahydroquinoline of the ligand.
Enantioselective Synthesis of Pyrrole-Fused Piperazine and Piperazinone Derivatives via Ir-Catalyzed Asymmetric Allylic AminationACS Catalysis, 2016Co-Authors: Chun-xiang Zhuo, Xiao Zhang, Shu-li YouAbstract:
Ir-catalyzed intramolecular asymmetric Allylic Amination reaction of pyrrole derivatives was achieved. The pyrrole-fused piperazine and piperazinone derivatives could be easily accessed from the pyrrole-tethered Allylic carbonates in good yields and enantioselectivity (up to 98% ee).
Highly Regio‐ and Enantioselective Synthesis of N‐Substituted 2‐Pyridones: Iridium‐Catalyzed Intermolecular Asymmetric Allylic Amination.ChemInform, 2015Co-Authors: Xiao Zhang, Ze-peng Yang, Lin Huang, Shu-li YouAbstract:
The Ir-catalyzed asymmetric Allylic Amination of 2-hydroxypyridines with allyl methyl carbonates (II) is reported for the first time.
Toshiyuki Itoh – One of the best experts on this subject based on the ideXlab platform.
Enantioselective Allylic Amination of Trifluoromethyl Group Substituted Racemic and Unsymmetrical 1,3-Disubstituted Allylic Esters by Palladium Catalysts.ChemInform, 2014Co-Authors: Motoi Kawatsura, Shou Terasaki, Maki Minakawa, Takuya Hirakawa, Kazunori Ikeda, Toshiyuki ItohAbstract:
A facile protocol for the regio- and enantioselective Allylic Amination of Allylic esters to give the corresponding α-type Allylic amines is presented.
Enantioselective Allylic Amination of Trifluoromethyl Group Substituted Racemic and Unsymmetrical 1,3-Disubstituted Allylic Esters by Palladium CatalystsOrganic letters, 2014Co-Authors: Motoi Kawatsura, Shou Terasaki, Maki Minakawa, Takuya Hirakawa, Kazunori Ikeda, Toshiyuki ItohAbstract:
The palladium-catalyzed regio- and enantioselective Allylic Amination of trifluoromethyl group substituted racemic and unsymmetrical 1,3-disubstituted Allylic esters has been accomplished. The enantioselective formation of the α-type Allylic amines was attained by the dynamic kinetic asymmetric transformation (DYKAT).
Ruthenium-catalyzed regio- and enantioselective Allylic Amination of racemic 1-arylallyl esters.Organic letters, 2014Co-Authors: Motoi Kawatsura, Shou Terasaki, Kenta Uchida, Hiroaki Tsuji, Maki Minakawa, Toshiyuki ItohAbstract:
The regio- and enantioselective Allylic Amination of racemic monosubstituted Allylic esters, such as 1-arylallyl acetates, with cyclic secondary amines has been accomplished. The RuCl3/(S,S)-ip-pybox catalyst system has effectively catalyzed the reaction to afford the enantiomerically enriched branch-type Allylic amines with perfect regioselectivity and high enantioselectivity.
Motoi Kawatsura – One of the best experts on this subject based on the ideXlab platform.
Synthesis of α-Tertiary Amines by the Ruthenium-catalyzed Regioselective Allylic Amination of Tertiary Allylic EstersChemistry Letters, 2020Co-Authors: Shota Mizuno, Hiroaki Tsuji, Yasuhiro Uozumi, Motoi KawatsuraAbstract:
We demonstrated a ruthenium-catalyzed regioselective Allylic Amination of tertiary Allylic esters with various amines using [Cp*Ru(CH3CN)3][PF6]/5,5′-dimethyl-2,2′-bipyridine (5,5′-diMe-2,2′-bpy) a…
Ruthenium-catalyzed regioselective Allylic Amination of 2,3,3-trifluoroAllylic carbonatesOrganic & biomolecular chemistry, 2017Co-Authors: Shin-ichi Isobe, Shou Terasaki, Taisyun Hanakawa, Shota Mizuno, Motoi KawatsuraAbstract:
We demonstrated the ruthenium-catalyzed Allylic Amination of 2,3,3-trifluoroAllylic carbonates with several types of amines. The reactions proceeded with several types of amines, and succeeded in obtaining polyfluorinated terminal alkenes possessing branched Allylic amines as a single regioisomer.
Regioselective Construction of α,α-Disubstituted
Allylic Amines by the Ruthenium-Catalyzed Allylic Amination of Tertiary
Allylic Acetates, 2017Co-Authors: Shota Mizuno, Shou Terasaki, Toru Shinozawa, Motoi KawatsuraAbstract:
The ruthenium-catalyzed regioselective
Allylic Amination of tertiary
Allylic acetates with several types of amines has been accomplished.
The reaction was effectively catalyzed by Cp*RuCl2/5,5′-dimethyl-2,2′-bipyridine
or its related ruthenium catalyst systems, and α,α-disubstituted
Allylic amines were formed as a single regioisomer in moderate to