Anthemis

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Slobodan Milosavljević - One of the best experts on this subject based on the ideXlab platform.

  • NF-κB DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula.
    Natural product research, 2010
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Christoph A. Klaas, Irmgard Merfort, Slobodan Milosavljević
    Abstract:

    Previous investigations of Anthemis arvensis L. and Anthemis cotula L., species growing wild in Serbia, revealed linear sesquiterpene lactones (SLs) with unusual types of skeleton, named antheindurolides and anthecotuloides. The NF-κB DNA binding activity of four of those SLs as well as from compounds representing structural parts of the SLs is reported in this article. The relationship between their structure and NF-κB inhibition potency is briefly discussed.

  • Cytotoxic guaianolide from Anthemis segetalis (Asteraceae).
    Phytotherapy research : PTR, 2010
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Danijela Stešević, Siniša Radulović, Milan Lazić, Slobodan Milosavljević
    Abstract:

    Two epimeric guaianolides were isolated from the aerial parts of Anthemis segetalis. These compounds have not been detected in any Anthemis species so far. One of them was tested for cytotoxicity against human cervical cancer (HeLa) and murine melanoma (B16) cell lines showing appreciable activity.

  • Sesquiterpene lactones from the aerial parts of Anthemis arvensis L.
    Biochemical Systematics and Ecology, 2006
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Vlatka Vajs, Vele Tešević, Slobodan Macura, Pedja Janaćković, Slobodan Milosavljević
    Abstract:

    Two known sesquiterpene lactones, antheindurolides A and B, together with five new related lactones with the same unusual skeleton were isolated from the aerial parts of Anthemis arvensis growing in Serbia. The originally proposed structure of antheindurolide B was revised. This (antheindurolide) type of lactones, detected so far only in the genus Anthemis (Anthemis indurata, Anthemis pseudocotula and Anthemis cotula) could be of chemotaxonomic significance.

  • Phytochemical investigation of Anthemis cotula
    Journal of the Serbian Chemical Society, 2006
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Vlatka Vajs, Vele Tešević, T Pedja Janackovic, Slobodan Milosavljević
    Abstract:

    The investigation of roots of Anthemis cotula (Asteraceae) from east Ser- bia revealed, in addition to polyacetylenes previously isolated from the same spe- cies, three prenylated 4-hydroxyacetophenones, detected for the first time in any Anthemis species. It is possible that they act as phytoalexins in the plant. From the aerial parts, six linear sesquiterpene lactones (four known and two new ones), as well as two known flavones, apigenin and hispidulin, were isolated.

  • Essential Oil of Anthemis montana
    Journal of Essential Oil Research, 1998
    Co-Authors: Vanja Bulatović, Vlatka Vajs, Slobodan Milosavljević, Nebojša Menković, Dejan Djokovic
    Abstract:

    Abstract The essential oil of Anthemis montana L. (Asteraceae) has been analyzed using GC and GC/MS. Forty-two components were identified. The major fractions belonged to α-thujone (46.9%), β-thujone (16.0%), and trans-chrysanthemyl acetate (11.3%) amounting up to 74.2% of the total oil content.

Maurizio Bruno - One of the best experts on this subject based on the ideXlab platform.

Kenan Buldurun - One of the best experts on this subject based on the ideXlab platform.

Werner Herz - One of the best experts on this subject based on the ideXlab platform.

Ivan Vuckovic - One of the best experts on this subject based on the ideXlab platform.

  • NF-κB DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula.
    Natural product research, 2010
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Christoph A. Klaas, Irmgard Merfort, Slobodan Milosavljević
    Abstract:

    Previous investigations of Anthemis arvensis L. and Anthemis cotula L., species growing wild in Serbia, revealed linear sesquiterpene lactones (SLs) with unusual types of skeleton, named antheindurolides and anthecotuloides. The NF-κB DNA binding activity of four of those SLs as well as from compounds representing structural parts of the SLs is reported in this article. The relationship between their structure and NF-κB inhibition potency is briefly discussed.

  • Cytotoxic guaianolide from Anthemis segetalis (Asteraceae).
    Phytotherapy research : PTR, 2010
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Danijela Stešević, Siniša Radulović, Milan Lazić, Slobodan Milosavljević
    Abstract:

    Two epimeric guaianolides were isolated from the aerial parts of Anthemis segetalis. These compounds have not been detected in any Anthemis species so far. One of them was tested for cytotoxicity against human cervical cancer (HeLa) and murine melanoma (B16) cell lines showing appreciable activity.

  • Sesquiterpene lactones from the aerial parts of Anthemis arvensis L.
    Biochemical Systematics and Ecology, 2006
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Vlatka Vajs, Vele Tešević, Slobodan Macura, Pedja Janaćković, Slobodan Milosavljević
    Abstract:

    Two known sesquiterpene lactones, antheindurolides A and B, together with five new related lactones with the same unusual skeleton were isolated from the aerial parts of Anthemis arvensis growing in Serbia. The originally proposed structure of antheindurolide B was revised. This (antheindurolide) type of lactones, detected so far only in the genus Anthemis (Anthemis indurata, Anthemis pseudocotula and Anthemis cotula) could be of chemotaxonomic significance.

  • Phytochemical investigation of Anthemis cotula
    Journal of the Serbian Chemical Society, 2006
    Co-Authors: Ivan Vuckovic, Ljubodrag Vujisić, Vlatka Vajs, Vele Tešević, T Pedja Janackovic, Slobodan Milosavljević
    Abstract:

    The investigation of roots of Anthemis cotula (Asteraceae) from east Ser- bia revealed, in addition to polyacetylenes previously isolated from the same spe- cies, three prenylated 4-hydroxyacetophenones, detected for the first time in any Anthemis species. It is possible that they act as phytoalexins in the plant. From the aerial parts, six linear sesquiterpene lactones (four known and two new ones), as well as two known flavones, apigenin and hispidulin, were isolated.