Avitaminosis

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Kon' Iia - One of the best experts on this subject based on the ideXlab platform.

  • Morphological characteristics of enterocyte proliferation and differentiation processes in Avitaminosis A
    Voprosy pitaniia, 1991
    Co-Authors: Kon' Iia
    Abstract:

    A significant decrease in the total number of mitotically dividing cells (per 1 crypt), especially in the lower portions of the intestine, was observed in rats with Avitaminosis A. The levelling of differences in the number of goblet cells in the upper and lower portions of the intestine was also recorded in the animals with Avitaminosis A. The investigations conducted have evidenced retinol participation in differentiation and, to a lesser extent, in proliferation of epitheliocytes of the rat small intestine.

  • The effect of vitamin A on the glycoprotein fraction composition of rat plasma
    Voprosy meditsinskoi khimii, 1991
    Co-Authors: Kon' Iia
    Abstract:

    Content of main glycoprotein fractions was studied in rat blood plasma under conditions of vitamin A Avitaminosis and of subnormal consumption of the vitamin. Main protein fractions were estimated simultaneously with relative content of glycoproteins which was calculated per mg of total proteins. Relative content of gamma-glycoproteins was increased in Avitaminosis A, which appears to occur due to elevation of gamma-globulin synthesis in response to secondary infection or intoxication, while the level of alpha 1- and alpha 2-glycoproteins was decreased simultaneously as a result of possible impairment of protein glycosylation in liver tissue. Subnormal consumption of retinol did not alter content of many protein fractions in blood, however under these conditions absolute content of alpha 1-, alpha 2- and beta 2-glycoproteins as well as relative content of alpha 2-glycoproteins were decreased, thus leading to increase in relative content of underglycosylated proteins in blood. Vitamin A appears to be essential for biosynthesis of individual but not of total blood glycoproteins.

Markov Iug - One of the best experts on this subject based on the ideXlab platform.

  • Disorders of zinc transport through the ileal epithelium in vitamin A deficiency and ischemia
    Arkhiv anatomii gistologii i embriologii, 1990
    Co-Authors: Markov Iug
    Abstract:

    By means of histochemical revealing of zinc and applying radioactive isotope 65Zn accumulation, absorption and distribution of cations of this metal in the mucous membrane of the iliac intestine have been studied in chicken, normal, at ischemia and at A-Avitaminosis. An essential zinc-depositing ability is peculiar to coverings of mucus upon the intestine epithelium, and among intracellular components--to smooth endoplasmic reticulum. A-Avitaminosis and especially ischemia result in increasing permeability of the apical part of the external membrane of epitheliocytes, in overloading of the latter with zinc cations, when they are introduced into the intestine, as well as in decreasing transepithelial transport of zinc. The changes mentioned are accompanied with certain disturbances in the barrier function of the intestinal epithelium.

Monica Lage Da Rocha - One of the best experts on this subject based on the ideXlab platform.

  • avitaminoses e suas manifestacoes bucais Avitaminosis and bucal manifestations
    International Journal of Dentistry, 2003
    Co-Authors: Michelle Lopes Mendes, Cacio Lopes Mendes, Monica Lage Da Rocha
    Abstract:

    As vitaminas sao potentes compostos orgânicos que ocorrem em baixas concentracoes nos alimentos desempenhando funcoes vitais e especificas nas celulas e nos tecidos do organismo. Nao podem ser sintetizadas pelo organismo e, a sua ausencia ou utilizacao inadequada resultam em doencas carencias especificas. As deficiencias vitaminicas podem acarretar manifestacoes bucais como: gengivites, doencas periodontais, escorbuto oral, hemorragias dos tecidos bucais, queilites, glossites e estomatites. Para que haja o tratamento adequado destas manifestacoes, devemos eliminar o agente causador local, ter uma dieta alimentar balanceada para que se possa prevenir o aparecimento de lesoes na cavidade oral. Entretanto, sabemos que a ingestao de dietas exclusivamente nao curam a doenca ja instalada, porem, e necessario associa-la a terapia medicamentosa e suplementacao vitaminica, de modo, a promover saude e devolver ao individuo uma vida mais saudavel. Este trabalho tem como objetivo fazer uma revisao bibliografica das principais vitaminas e correlacionar suas deficiencias com as manifestacoes na cavidade oral.

Gideon Eshel - One of the best experts on this subject based on the ideXlab platform.

Juana Maria Solano Rodriguez - One of the best experts on this subject based on the ideXlab platform.

  • ensayo experimental sobre Avitaminosis k
    Anales de la Facultad de Medicina, 2014
    Co-Authors: Juana Maria Solano Rodriguez
    Abstract:

    We have made an experimental test of Avitaminosis K in order to study the hitipatologicas and radiological lesions in relation to haematological abnormalities and changes in prothrombin in the blood. The clinical picture observed in animals is similar in all respects to that described by Dam, Schonheyder, Almquist and colleagues. With respect to prothrombin time values ​​Quick, we note: a) Normal values: In the control animals, normal prothrombin time is 85% and the Quick time is 45 seconds. b) In animals lack, the higher the vitamin deficiency, Quick time is greater and the prothrombin time decreased to 5% of normal for chickens of the same age. c) The administration of 2-methyl-1,4-naphtoquinona animals lack the time with high and low prothrombin rate Quick, varied these values ​​into the normal range, but without reaching the primitive values​​. Review radiologico.-In Dr. G. Faldini opinion, in our cases is only a delay of osteogenesis without any other alteration in bone architecture. We have not found any reference in the literature on the subject. Hematology; a) In normal animals observed for 30 days, it was found that the values ​​were similar to those of Dam, Palmer, and Wintrobe Bielys. Studies in series in this time interval allow to observe a similar desglobulizacion to newborns, discreetly hypochromic and tends to return after 30 days. b) In animals lack, for the same day with the controls, it is observed that the higher the vitamin deficiency, anemia is more frankly hypochromic and tendency to macrocytosis. No signs of regression is noted. c) The blood counts in normal animals with lymphocytic predominance. In animals, a significant decrease in lack lymphocytosis with neutrophilia and correlative appearance of juveniles. d) Bone marrow: The normal myelogram is erythroblastic and lymphocytic type, with regular rate of mitosis; weak positive reaction of the oxidases. In animals lack the myelogram is poor in cellular elements, with a high proportion of fat. Disappearance of mitosis. Oxidase reaction to negative, presenting a human-like appearance aplastic anemia. Histopatologicas.- lesions were observed: a) Fatty degeneration of the heart. b) Discrete greasy and presence of hemorrhagic foci in the liver degeneration. c) Spleen: poor blood, more or less preserved histological appearance. d) Kidneys: discrete cortical degeneration. e) Stomach and Intestine subserosal hemorrhages; small ulcer-like erosions.