The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform
Yuexin Huang - One of the best experts on this subject based on the ideXlab platform.
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Intelligent Hydrogels for Drug Delivery System
Recent Patents on Drug Delivery & Formulation, 2011Co-Authors: Liumin He, Yuexin HuangAbstract:Intelligent hydrogel, also known as smart hydrogels, are materials with great potential for development in drug delivery system. Intelligent hydrogel also has the ability to perceive as a signal structure change and stimulation. The review introduces the temperature-, pH-, electric signal-, Biochemical Molecule-, light- and pressure- sensitive hydrogels. Finally, we described the application of intelligent hydrogel in drug delivery system and the recent patents involved for hydrogel in drug delivery.
Liumin He - One of the best experts on this subject based on the ideXlab platform.
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Intelligent Hydrogels for Drug Delivery System
Recent Patents on Drug Delivery & Formulation, 2011Co-Authors: Liumin He, Yuexin HuangAbstract:Intelligent hydrogel, also known as smart hydrogels, are materials with great potential for development in drug delivery system. Intelligent hydrogel also has the ability to perceive as a signal structure change and stimulation. The review introduces the temperature-, pH-, electric signal-, Biochemical Molecule-, light- and pressure- sensitive hydrogels. Finally, we described the application of intelligent hydrogel in drug delivery system and the recent patents involved for hydrogel in drug delivery.
Francesca Iacopi - One of the best experts on this subject based on the ideXlab platform.
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Toward Label-Free Biosensing With Silicon Carbide: A Review
IEEE Access, 2016Co-Authors: Oren Cooper, Bei Wang, Christopher L. Brown, Joe Tiralongo, Francesca IacopiAbstract:Recent innovation in microelectrical–mechanical systems (MEMSs) and plasmonics-based technologies has opened up perspectives for label-free sensing of biological and chemical analytes. Label-free sensing would enable increased sensitivity and miniaturization capabilities for biosensing devices. Silicon carbide is a semiconductor material that happens to possess ideal properties for augmenting both the MEMS/nanoelectromechanical systems and the plasmonics routes. It has remarkable chemical and biological inertness resulting in a high degree of biocompatibility, as well as pronounced mechanical resilience. In addition, it is an efficient (low loss) plasmonic metamaterial. Its cubic polytype can be grown on silicon wafers, allowing easy micromachining into building blocks for sensing devices, scalable to large volume production. Finally, silicon carbide is an ideal starting material for a controlled, wafer-scale growth of graphene, offering an additional wealth of excellent properties for nanosensing. The combination of all of these capabilities makes silicon carbide an outstanding material platform for the realization of label-free, analyte-specific, and highly sensitive Biochemical Molecule detection systems. These technologies will open exciting horizons in terms of high throughput, efficient drug screening, and early pathogen detection.
Shuliang Lu - One of the best experts on this subject based on the ideXlab platform.
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Hydrogen Peroxide: A Potential Wound Therapeutic Target
Medical Principles and Practice, 2017Co-Authors: Qi Wang, Shuliang LuAbstract:Hydrogen peroxide (H2O2) is a topical antiseptic used in wound cleaning which kills pathogens through oxidation burst and local oxygen production. Hydrogen peroxide had been reported to be a reactive Biochemical Molecule synthesized by various cells which influences biological behavior through multiple mechanisms: alterations of membrane potential, generation of new Molecules and changing intracellular redox balance which results in activation or inactivation of different signaling transduction pathways. Contrary to the traditional viewpoint that H2O2 probably impairs tissue through its high oxidative property, however, a proper level of H2O2 is considered as an important requirement for normal wound healing. Although the present clinical use of H2O2 is still limited to the elimination of microbial contamination and sometimes hemostasis, better understanding towards the sterilization ability and cell behavior regulatory function of H2O2 within wound will enhance the potential to exogenously augment and manipulate healing.
Qi Wang - One of the best experts on this subject based on the ideXlab platform.
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Hydrogen Peroxide: A Potential Wound Therapeutic Target
Medical Principles and Practice, 2017Co-Authors: Qi Wang, Shuliang LuAbstract:Hydrogen peroxide (H2O2) is a topical antiseptic used in wound cleaning which kills pathogens through oxidation burst and local oxygen production. Hydrogen peroxide had been reported to be a reactive Biochemical Molecule synthesized by various cells which influences biological behavior through multiple mechanisms: alterations of membrane potential, generation of new Molecules and changing intracellular redox balance which results in activation or inactivation of different signaling transduction pathways. Contrary to the traditional viewpoint that H2O2 probably impairs tissue through its high oxidative property, however, a proper level of H2O2 is considered as an important requirement for normal wound healing. Although the present clinical use of H2O2 is still limited to the elimination of microbial contamination and sometimes hemostasis, better understanding towards the sterilization ability and cell behavior regulatory function of H2O2 within wound will enhance the potential to exogenously augment and manipulate healing.
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Optimizing the quality factor of a wideband guided-mode resonance biosensor
Applied Physics A, 2014Co-Authors: Qi Wang, Dawei Zhang, Zhenyun Wang, Yuanshen HuangAbstract:This work studies the effect of the Biochemical molecular layer on the quality factor of guided-mode resonance (GMR) filter of an ultrasensitive label-free biosensor. A GMR biosensor with a narrower bandwidth has a higher sensitivity but requires much higher accuracy in its fabrication process. In this study, we have managed to present a GMR filter with a narrow bandwidth that requires less precision by controlling the thickness of the Biochemical Molecule layer, which increases the Q factor by up to three times.