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J P Vermeersch - One of the best experts on this subject based on the ideXlab platform.

  • towards eradication of Bovine Tuberculosis in the european union
    Veterinary Microbiology, 2006
    Co-Authors: F Reviriego J Gordejo, J P Vermeersch
    Abstract:

    This paper reviews the developments and progress towards eradication of Bovine Tuberculosis in the European Union (EU). A historical view of the EU legislation aimed at mainly approximating provisions on intra-community in cattle trade explains the present EU policies. The variety of cattle breeding systems and environmental conditions in the EU leads to different epidemiological situations. The current situation of Bovine Tuberculosis in the EU Member States is summarised, and current policy in the EU is outlined.

Gillian Colclough - One of the best experts on this subject based on the ideXlab platform.

  • 'Filthy vessels': milk safety and attempts to restrict the spread of Bovine Tuberculosis in Queensland.
    Health and History, 2020
    Co-Authors: Gillian Colclough
    Abstract:

    Bovine Tuberculosis is a dangerous mycobacterium that can be conveyed to humans in the meat and milk of cattle. By the mid-1800s, when health scientists began arguing about its zoonotic potential and danger to humans, the disease was well established in Australian cattle herds. This article examines the Queensland response to Bovine Tuberculosis from the late 1800s to the 1940s, when the problem of tubercular cattle could no longer be ignored. It shows that despite widespread concern about milk safety and increasing knowledge of the disease's aetiology, the Queensland government directed its milk safety activities towards public health education rather than the inadequacies of the dairy industry's approach to Bovine Tuberculosis. As such, it was tardy in addressing Bovine Tuberculosis.

  • 'Filthy Vessels': Milk Safety and Attempts to Restrict the Spread of Bovine Tuberculosis
    2020
    Co-Authors: Gillian Colclough
    Abstract:

    Bovine Tuberculosis is a dangerous mycobacterium that can be conveyed to humans in the meat and milk of cattle. By the mid-1800s, when health scientists began arguing about its zoonotic potential and danger to humans, the disease was well established in Australian cattle herds. This article examines the Queensland response to Bovine Tuberculosis from the late 1800s to the 1940s, when the problem of tubercular cattle could no longer be ignored. It shows that despite widespread concern about milk safety and increasing knowledge of the disease’s aetiology, the Queensland government directed its milk safety activities towards public health education rather than the inadequacies of the dairy industry’s approach to Bovine Tuberculosis. As such, it was tardy in addressing Bovine Tuberculosis. Cow’s milk has long been part of the western diet. Untainted, it is a useful resource where breastfeeding is not possible, a valuable source of nutrition for growing children and a popular beverage or processed food for adults; but when infected with pathogens such as those that cause gastroenteritis, diarrhoea, typhoid, or Bovine Tuberculosis, milk can conceal life-threatening hazards. Such was especially the case in the late–nineteenth and early–twentieth century when thousands of infants and children were made seriously or fatally ill by ingesting untreated and unrefrigerated milk. Surviving a childhood infection was often not the end of the encounter for children who caught Tuberculosis from milk. Tubercular infections can lie dormant and reappear aggressively at a time of later frailty; consequently, Tuberculosis is particularly insidious among the diseases carried in milk. The Bovine form is closely related to that most associated with human infection—what was once familiar as pulmonary Tuberculosis, consumption, phthisis, or TB (sometimes Mtb), is known scientifi cally as Mycobacterium Tuberculosis. 1

F Reviriego J Gordejo - One of the best experts on this subject based on the ideXlab platform.

  • towards eradication of Bovine Tuberculosis in the european union
    Veterinary Microbiology, 2006
    Co-Authors: F Reviriego J Gordejo, J P Vermeersch
    Abstract:

    This paper reviews the developments and progress towards eradication of Bovine Tuberculosis in the European Union (EU). A historical view of the EU legislation aimed at mainly approximating provisions on intra-community in cattle trade explains the present EU policies. The variety of cattle breeding systems and environmental conditions in the EU leads to different epidemiological situations. The current situation of Bovine Tuberculosis in the EU Member States is summarised, and current policy in the EU is outlined.

Ashish Bhaladhare - One of the best experts on this subject based on the ideXlab platform.

  • Single nucleotide polymorphism in cattle and its association with susceptibility to Bovine Tuberculosis
    Indian Journal of Field Veterinarians, 2020
    Co-Authors: Ashish Bhaladhare, Amit Kumar, Deepak Sharma
    Abstract:

    Bovine Tuberculosis is an important disease of cattle with zoonotic importance. A resource population comprising of 35 Case and 49 Control animals of indigenous cattle population was genotyped for a SNP from intergenic region of SLC6A6 gene, which have an established association with Bovine Tuberculosis susceptibility in Holstein-Freisian cattle population. Polymorphism in indigenous resource population at the targeted SNP revealed the presence of this SNP in indigenous cattle also. Both the alleles i.e. G and T and all possible three genotypes i.e. GG, GT and TT were observed in indigenous cattle. Low Polymorphic Information Content but high heterozygocity was observed at this SNP. The probability values showed that the genotype (P=0.38) as well as allele (P=0.53) had no significant effect on occurrence of Bovine Tuberculosis.

  • Association of single nucleotide polymorphisms in IFNGR1 and IFNGR2 genes with Bovine Tuberculosis
    Indian Journal of Animal Research, 2019
    Co-Authors: Ashish Bhaladhare, Anuj Chauhan, Arvind Sonwane, Amit Kumar, Pushpendra Kumar, Subodh Kumar, Sushil Kumar, Manjit Panigrahi, Bharat Bhushan
    Abstract:

    Interferon Gamma Receptor (IFNGR) genes play an important role in the immune response against mycobacteria by regulating the proinflammatory cytokine Interferon Gamma (IFNG) alongwith subsequent mycobactericidal milieu and are potential strong candidates for investigating genetic basis of disease resistance. Present investigation was aimed at exploring the association of one SNP in IFNGR1 gene and two SNPs in IFNGR2 gene with susceptibility/resistance against Bovine Tuberculosis infection in cattle. All the three SNPs under investigation (rs109049057, rs109579937 and rs110689128) revealed polymorphism. SNP loci rs109049057 was found to be significantly (P < 0.01) associated with susceptibility to Bovine Tuberculosis in cattle in our case control population. The SNP was non-synonymous, suggesting its functional role in the immune response against Bovine Tuberculosis.

  • Association of single nucleotide polymorphisms in IFNGR1 and IFNGR2 genes with Bovine Tuberculosis
    Indian Journal of Animal Research, 2019
    Co-Authors: Anuj Chauhan, Ashish Bhaladhare, Arvind Sonwane, Amit Kumar, Pushpendra Kumar, Subodh Kumar, Sushil Kumar, Manjit Panigrahi, Bharat Bhushan
    Abstract:

    Interferon Gamma Receptor (IFNGR) genes play an important role in the immune response against mycobacteria by regulating the proinflammatory cytokine Interferon Gamma (IFNG) alongwith subsequent mycobactericidal milieu and are potential strong candidates for investigating genetic basis of disease resistance. Present investigation was aimed at exploring the association of one SNP in IFNGR1 gene and two SNPs in IFNGR2 gene with susceptibility/resistance against Bovine Tuberculosis infection in cattle. All the three SNPs under investigation (rs109049057, rs109579937 and rs110689128) revealed polymorphism. SNP loci rs109049057 was found to be significantly (P less than 0.01) associated with susceptibility to Bovine Tuberculosis in cattle in our case control population. The SNP was non-synonymous, suggesting its functional role in the immune response against Bovine Tuberculosis.

Robbie A. Mcdonald - One of the best experts on this subject based on the ideXlab platform.

  • animal health how to control Bovine Tuberculosis
    Nature, 2014
    Co-Authors: Robbie A. Mcdonald
    Abstract:

    A model of the transmission and spread of Bovine Tuberculosis in Britain suggests that controlling the epidemic will require large-scale cattle slaughter or a major rethink of combined control strategies. See Letter p.228 Bovine Tuberculosis (TB) is a major economic burden on the cattle industry, particularly in the United Kingdom. Attempts to control it, especially by targeting the environmental reservoir in the badger population, have been politically controversial and largely unsuccessful. Ellen Brooks-Pollock, Gareth Roberts and Matt Keeling have used farm movement and Bovine TB incidence data to construct a mechanistic model that they use to tease apart the factors contributing to epidemic Bovine TB spread. Although the environmental reservoir is important for infection in the short term, it is not a major determinant of long-term spread, and most herd outbreaks are caused by several transmission routes. The authors find that only intensive control measures that focus on cattle are likely to be effective, and that control of local badger populations is unlikely to have a substantial impact.

  • Badgers and Bovine Tuberculosis.
    Current Biology, 2014
    Co-Authors: Robbie A. Mcdonald
    Abstract:

    What is Tuberculosis in badgers? Tuberculosis in European badgers Meles meles is caused by Mycobacterium bovis, the same pathogen that causes Bovine Tuberculosis in cattle. Pasteurization of cows’ milk and childhood vaccination have greatly reduced human cases of Bovine Tuberculosis infection in the developed world, though it remains a public health challenge in many developing countries. In parts of the UK and Ireland, where Bovine Tuberculosis is a large and growing animal health problem, badgers are a wildlife reservoir and an important source of infection for cattle.