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Harold E Carlson - One of the best experts on this subject based on the ideXlab platform.

  • approach to the patient with gynecomastia
    The Journal of Clinical Endocrinology and Metabolism, 2011
    Co-Authors: Harold E Carlson
    Abstract:

    Gynecomastia is a common and sometimes distressing condition that may occur in males of all ages. Although most cases have benign causes and many are self-limited, male Breast Enlargement may also be a sign of underlying systemic disease or drug toxicity. Although rare, male Breast cancer must also be considered in the differential diagnosis. A careful diagnostic evaluation should be pursued, tailored to the individual patient's circumstances. Treatment may include reassurance, medication, or surgery.

  • gynecomastia its features and when and how to treat it
    Cleveland Clinic Journal of Medicine, 2004
    Co-Authors: Shirley Bembo, Harold E Carlson
    Abstract:

    Gynecomastia is common, being present in 30% to 50% of healthy men. A general medical history and careful physical examination with particular attention to features suggestive of Breast cancer often suffice for evaluation in patients without symptoms or those with incidentally discovered Breast Enlargement. Men with recent-onset gynecomastia or mastodynia need a more detailed evaluation, including selected laboratory tests to search for an underlying cause. Treatment depends on the cause and may include observation, withdrawal of an offending drug, therapy of an underlying disease, giving androgen or antiestrogen drugs, or plastic surgery.

Lawrence W Bassett - One of the best experts on this subject based on the ideXlab platform.

  • imaging characteristics of malignant lesions of the male Breast
    Radiographics, 2006
    Co-Authors: Lina Chen, Prem K Chantra, Linda H Larsen, Premsri Barton, Montanan Rohitopakarn, Lawrence W Bassett
    Abstract:

    Most men referred for Breast imaging have palpable lumps, Breast Enlargement, or tenderness. Most of the evaluated lesions are benign. Male Breast cancer accounts for less than 1% of total male Breast lesions. Differentiation between benign and malignant masses is critical because it alleviates patient anxiety and allows unnecessary procedures to be avoided. Clinically suspicious lesions referred for imaging should first be evaluated with mammography. In patients with questionable findings at mammography and for lesions that are difficult to image with mammography, ultrasonography (US) is often useful for further characterization. A discrete mass at mammography or US is suspicious for malignancy. The relationship of the mass to the nipple should be carefully assessed; an eccentric location is highly suspicious for cancer. Secondary signs occur earlier in male patients because of smaller Breast size. Such signs include nipple retraction, skin ulceration or thickening, increased Breast trabeculation, and axillary adenopathy. US of the axillary region is helpful for staging. At pathologic analysis, cystic lesions commonly demonstrate malignant findings; therefore, all cysts and complex masses should be worked up as potentially malignant lesions. Benign conditions that may mimic male Breast cancer include gynecomastia, lipoma, epidermal inclusion cyst, pseudoangiomatous stromal hyperplasia, and intraductal papilloma.

Veli Yalcin - One of the best experts on this subject based on the ideXlab platform.

  • is prophylactic Breast radiotherapy necessary in all patients with prostate cancer and gynecomastia and or Breast pain
    The Journal of Urology, 2010
    Co-Authors: Haluk Ozen, Fadil Akyol, Gokhan Toktas, Saadettin Eskicorapci, Erdinc Unluer, Ugur Kuyumcuoglu, Erkan Abay, Ibrahim Cureklibatur, Meric Sengoz, Veli Yalcin
    Abstract:

    Purpose: We investigated the efficacy of prophylactic radiotherapy for gynecomastia/Breast pain induced by 150 mg bicalutamide in a prospective, randomized, multi-institutional trial.Materials and Methods: After definitive treatment for localized prostate cancer 125 patients were randomized to 12 Gy radiotherapy before bicalutamide as prophylactic radiotherapy (53) or bicalutamide only for nonprophylactic radiotherapy (72). The incidence of gynecomastia, Breast pain and tenderness, and discomfort perceived by the patients was assessed by physical examination and direct questioning at 3, 6 and 12 months of followup.Results: At the end of 12 months the gynecomastia rate was 15.8% in the prophylactic group and 50.8% in the nonprophylactic group (p <0.001). On patient evaluation the Breast Enlargement rate was 34.4%. The severity of Breast pain and tenderness was not different between the groups. The Breast pain rate was 36.4% and 49.2% by 12 months in the prophylactic and nonprophylactic groups, and the rate...

Ingrid Schlenz - One of the best experts on this subject based on the ideXlab platform.

P. Kamparoudi - One of the best experts on this subject based on the ideXlab platform.

  • Galactorrhea, mastodynia and gynecomastia as the first manifestation of lung adenocarcinoma. A case report
    'Elsevier BV', 2019
    Co-Authors: A. Lazopoulos, D. Krimiotis, N.c. Schizas, T. Rallis, A.s. Gogakos, F. Chatzinikolaou, T. Tsiouda, P. Zarogoulidis, P. Sarafis, P. Kamparoudi
    Abstract:

    Gynecomastia with mastodynia and galactorrhea as a paraneoplastic syndrome due to lung cancer with complete response after surgical excision is rare.A 62-year-old Caucasian male presented with mastodynia, galactorrhea and right Breast Enlargement. Chest x-ray revealed a left upper lobe tumor. The patient had high levels of serum beta-human chorionic gonadotropin (b-HCG) and prolactine. Complete staging was negative for metastases.A typical left upper lobectomy with radical mediastinal lymph node dissection was performed. Pathology report was consistent with a poorly differentiated adenocarcinoma (T2N1M0). Immunohistochemically, multinucleate cells and occasional mononucleate tumor cells showed positivity for human chorionic gonadotropin.The patient received adjuvant chemotherapy with cisplatin – navelbine. One year later physical examination showed regression of both gynecomastia and mastodynia and there was no nipple discharge, while he is free from local or distant metastatic disease and the b-HCG level is normal (1,59 mIU/ml).This case represents a very rare, first manifestation of lung cancer. Galactorrhea, mastodynia and gynecomastia were the initial symptoms, which totally resolved following the successful surgical resection and adjuvant chemotherapy. In this case, prolactin and b-HCG are useful biomarkers during follow up for checking local or distal recurrence of the disease. Keywords: Galactorrhea, Mastodynia, Gynecomastia, Lung adenocarcinom

  • galactorrhea mastodynia and gynecomastia as the first manifestation of lung adenocarcinoma a case report
    Respiratory medicine case reports, 2019
    Co-Authors: A. Lazopoulos, D. Krimiotis, T. Rallis, A.s. Gogakos, F. Chatzinikolaou, T. Tsiouda, P. Zarogoulidis, P. Sarafis, Nikolaos Schizas, P. Kamparoudi
    Abstract:

    Gynecomastia with mastodynia and galactorrhea as a paraneoplastic syndrome due to lung cancer with complete response after surgical excision is rare. A 62-year-old Caucasian male presented with mastodynia, galactorrhea and right Breast Enlargement. Chest x-ray revealed a left upper lobe tumor. The patient had high levels of serum beta-human chorionic gonadotropin (b-HCG) and prolactine. Complete staging was negative for metastases. A typical left upper lobectomy with radical mediastinal lymph node dissection was performed. Pathology report was consistent with a poorly differentiated adenocarcinoma (T2N1M0). Immunohistochemically, multinucleate cells and occasional mononucleate tumor cells showed positivity for human chorionic gonadotropin. The patient received adjuvant chemotherapy with cisplatin - navelbine. One year later physical examination showed regression of both gynecomastia and mastodynia and there was no nipple discharge, while he is free from local or distant metastatic disease and the b-HCG level is normal (1,59 mIU/ml). This case represents a very rare, first manifestation of lung cancer. Galactorrhea, mastodynia and gynecomastia were the initial symptoms, which totally resolved following the successful surgical resection and adjuvant chemotherapy. In this case, prolactin and b-HCG are useful biomarkers during follow up for checking local or distal recurrence of the disease.