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Fábio Clasen Chaves - One of the best experts on this subject based on the ideXlab platform.

  • Hypolipidemic and anti-inflammatory properties of phenolic rich Butia odorata fruit extract: potential involvement of paraoxonase activity.
    Biomarkers : biochemical indicators of exposure response and susceptibility to chemicals, 2020
    Co-Authors: Vanessa Plasse Ramos, Jessica Fernanda Hoffmann, Fábio Clasen Chaves, Pamela Gonçalves Da Silva, Pathise Souto Oliveira, Natália Pontes Bona, Mayara Sandrielly Pereira Soares, Juliane De Souza Cardoso, Augusto Schneider, Roselia Maria Spanevello
    Abstract:

    Aim: This study investigated the effects of polar Butia odorata fruit extract on metabolic, inflammatory, and oxidative stress parameters in rats submitted to a hyperlipidaemia condition induced by...

  • Stability of bioactive compounds in butiá (Butia odorata) fruit pulp and nectar.
    Food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Priscila Silveira Dos Santos, Camila Müller Dallmann, Francine Bonemann Madruga, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Abstract Butia odorata is a palm tree native to southern Brazil whose fruit (known as Butia) and leaves are used to make many food products and crafts. Butia contain several biologically active compounds with potential health benefits. However, processing conditions can alter quality attributes including bioactive compound content. This study evaluated the stability of bioactive compounds in Butia pulp upon pasteurization, during 12 months of frozen storage, and in Butia nectar after a 3-month storage period. Pulp pasteurization resulted in a reduction in phenolic, flavonoid, carotenoid, and ascorbic acid contents. After a 12-month frozen storage period, flavonoid, phenolic, and ascorbic acid contents decreased while carotenoid content remained unaltered. Carotenoid, ascorbic acid, and phenolic contents were unaffected by the 3-month storage of Butia nectar; however, flavonoid content and antioxidant potential were reduced. Despite bioactive compound degradation upon heat treatment and storage, Butia nectar remained rich in phenolics, especially (−)-epicatechin, rutin, and (+)-catechin.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination.
    Journal of agricultural and food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capao do Leao, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geog...

  • Probiotic butiá (Butia odorata) ice cream: Development, characterization, stability of bioactive compounds, and viability of Bifidobacterium lactis during storage
    LWT, 2017
    Co-Authors: Claudio Eduardo Dos Santos Cruxen, Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Cesar Valmor Rombaldi, Ângela Maria Fiorentini, Fábio Clasen Chaves
    Abstract:

    Abstract The addition of fruit with bioactive properties such as Butia odorata , henceforth called Butia, and probiotic bacteria may improve the nutritional and functional value of ice cream. In this study, Butia ice cream supplemented with Bifidobacterium lactis (Bl-04) was developed and characterized. Butia ice cream showed 71.2 g 100 g −1 of overrun, a density of 575 g cm −3 , and a pH of 4.7. During 90 days of frozen storage (−18 °C), a 10% reduction in total phenolic content and a 5% reduction in l -ascorbic acid content were observed. Carotenoids and flavonoids increased during frozen storage. Probiotic bacteria B . lactis (Bl-04) remained viable (above 10 6  CFU g −1 ) in Butia ice cream during storage, confirming the probiotic characteristic of the product. Sensory analyses showed that Butia ice cream had high acceptability (6.8–7.8) and purchase intent (above 80%). The combination of B . lactis and Butia fruit attributed functional characteristics to the ice cream.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination
    2016
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capão do Leão, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geographical origins of B. odorata and to identify primary and specialized metabolites responsible for the discrimination

Rosa Lia Barbieri - One of the best experts on this subject based on the ideXlab platform.

  • Correction: Effect of in vitro digestion on the functional properties of Psidium cattleianum Sabine (araçá), Butia odorata (Barb. Rodr.) Noblick (butiá) and Eugenia uniflora L. (pitanga) fruit extracts.
    Food & function, 2019
    Co-Authors: Juliana Vinholes, Sofia F Reis, Graciele Lemos, Rosa Lia Barbieri, Victor De Freitas, Rodrigo Cezar Franzon, Márcia Vizzotto
    Abstract:

    Correction for 'Effect of in vitro digestion on the functional properties of Psidium cattleianum Sabine (araçá), Butia odorata (Barb. Rodr.) Noblick (butiá) and Eugenia uniflora L. (pitanga) fruit extracts' by Juliana Vinholes, et al., Food Funct., 2018, 9, 6380-6390.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination.
    Journal of agricultural and food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capao do Leao, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geog...

  • In vitro assessment of the antihyperglycemic and antioxidant properties of araçá, butiá and pitanga
    Food Bioscience, 2017
    Co-Authors: Juliana Vinholes, Graciele Lemos, Rosa Lia Barbieri, Rodrigo Cezar Franzon, Márcia Vizzotto
    Abstract:

    Abstract Native fruits have been known as a great source of bioactive compounds with potential biological effects. The aim of this study was to investigate the α-glucosidase inhibition and antioxidant activities of araca (Psidium cattleianum Sabine), Butia (Butia odorata (Barb. Rodr.) Noblick) and pitanga (Eugenia uniflora L.) and relate their chemical composition with the observed biological activity. Samples of mature fruits were extracted with ethanol and the observed biological activities were dependent of the species and concentration as well. Aracas were the strongest α-glucosidase inhibitors (IC50 value of 25.4 ± 0.7 and 31.8 ± 0.7 µg/ml, respectively). Pitangas showed antiradical activities against DPPH, hydroxyl and nitric oxide radicals. Orange pitanga and Butia from Santa Vitoria do Palmar were the most active concerning anion superoxide radical. All fruits are rich in total phenolic compounds with values in the range of 454.5 ± 17.3–908.3 ± 60.8 mg of equivalents of chlorogenic acid/100 g fresh weight. Purple pitanga stood out due to their levels of anthocyanins and carotenoids. Fruits showed similar amounts of total sugars, aracas and pitangas showed higher levels of reducing sugars while Butias were the richest ones in non-reducing sugars. Fruits with lower IC50 values for α-glucosidase inhibition were correlated with higher concentrations of reducing sugars, phenolic compounds, anthocyanins and carotenoids and grouped by principal component analysis (PCA). The obtained results indicate that these native fruits are promising sources of α-glucosidase inhibitors and antioxidants that can be used to control glycemia in patients with type 2 Diabetes mellitus.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination
    2016
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capão do Leão, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geographical origins of B. odorata and to identify primary and specialized metabolites responsible for the discrimination

  • Butia spp. (Arecaceae): An overview
    Scientia Horticulturae, 2014
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Butia is a genus of palms (Arecaceae), autochthonous to South America with great potential for income generation. In order to better utilize and maintain the currently available genetic resources, it is necessary to pursue studies directed towards the taxonomic and systematic characterization (morphological, phenotypic, molecular, chemical, and reproductive) and conservation of Butia spp. Despite the long use of this plant, a limited number of scientific studies and publications are available on Butia spp., with a significant proportion of the literature written in Portuguese. This review intends to compile all the available information on the genus, covering several aspects of the plant and its potential applications.

Jessica Fernanda Hoffmann - One of the best experts on this subject based on the ideXlab platform.

  • Hypolipidemic and anti-inflammatory properties of phenolic rich Butia odorata fruit extract: potential involvement of paraoxonase activity.
    Biomarkers : biochemical indicators of exposure response and susceptibility to chemicals, 2020
    Co-Authors: Vanessa Plasse Ramos, Jessica Fernanda Hoffmann, Fábio Clasen Chaves, Pamela Gonçalves Da Silva, Pathise Souto Oliveira, Natália Pontes Bona, Mayara Sandrielly Pereira Soares, Juliane De Souza Cardoso, Augusto Schneider, Roselia Maria Spanevello
    Abstract:

    Aim: This study investigated the effects of polar Butia odorata fruit extract on metabolic, inflammatory, and oxidative stress parameters in rats submitted to a hyperlipidaemia condition induced by...

  • Stability of bioactive compounds in butiá (Butia odorata) fruit pulp and nectar.
    Food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Priscila Silveira Dos Santos, Camila Müller Dallmann, Francine Bonemann Madruga, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Abstract Butia odorata is a palm tree native to southern Brazil whose fruit (known as Butia) and leaves are used to make many food products and crafts. Butia contain several biologically active compounds with potential health benefits. However, processing conditions can alter quality attributes including bioactive compound content. This study evaluated the stability of bioactive compounds in Butia pulp upon pasteurization, during 12 months of frozen storage, and in Butia nectar after a 3-month storage period. Pulp pasteurization resulted in a reduction in phenolic, flavonoid, carotenoid, and ascorbic acid contents. After a 12-month frozen storage period, flavonoid, phenolic, and ascorbic acid contents decreased while carotenoid content remained unaltered. Carotenoid, ascorbic acid, and phenolic contents were unaffected by the 3-month storage of Butia nectar; however, flavonoid content and antioxidant potential were reduced. Despite bioactive compound degradation upon heat treatment and storage, Butia nectar remained rich in phenolics, especially (−)-epicatechin, rutin, and (+)-catechin.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination.
    Journal of agricultural and food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capao do Leao, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geog...

  • Probiotic butiá (Butia odorata) ice cream: Development, characterization, stability of bioactive compounds, and viability of Bifidobacterium lactis during storage
    LWT, 2017
    Co-Authors: Claudio Eduardo Dos Santos Cruxen, Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Cesar Valmor Rombaldi, Ângela Maria Fiorentini, Fábio Clasen Chaves
    Abstract:

    Abstract The addition of fruit with bioactive properties such as Butia odorata , henceforth called Butia, and probiotic bacteria may improve the nutritional and functional value of ice cream. In this study, Butia ice cream supplemented with Bifidobacterium lactis (Bl-04) was developed and characterized. Butia ice cream showed 71.2 g 100 g −1 of overrun, a density of 575 g cm −3 , and a pH of 4.7. During 90 days of frozen storage (−18 °C), a 10% reduction in total phenolic content and a 5% reduction in l -ascorbic acid content were observed. Carotenoids and flavonoids increased during frozen storage. Probiotic bacteria B . lactis (Bl-04) remained viable (above 10 6  CFU g −1 ) in Butia ice cream during storage, confirming the probiotic characteristic of the product. Sensory analyses showed that Butia ice cream had high acceptability (6.8–7.8) and purchase intent (above 80%). The combination of B . lactis and Butia fruit attributed functional characteristics to the ice cream.

  • Butia spp. (Arecaceae): An overview
    Scientia Horticulturae, 2014
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Butia is a genus of palms (Arecaceae), autochthonous to South America with great potential for income generation. In order to better utilize and maintain the currently available genetic resources, it is necessary to pursue studies directed towards the taxonomic and systematic characterization (morphological, phenotypic, molecular, chemical, and reproductive) and conservation of Butia spp. Despite the long use of this plant, a limited number of scientific studies and publications are available on Butia spp., with a significant proportion of the literature written in Portuguese. This review intends to compile all the available information on the genus, covering several aspects of the plant and its potential applications.

Cesar Valmor Rombaldi - One of the best experts on this subject based on the ideXlab platform.

  • Stability of bioactive compounds in butiá (Butia odorata) fruit pulp and nectar.
    Food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Priscila Silveira Dos Santos, Camila Müller Dallmann, Francine Bonemann Madruga, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Abstract Butia odorata is a palm tree native to southern Brazil whose fruit (known as Butia) and leaves are used to make many food products and crafts. Butia contain several biologically active compounds with potential health benefits. However, processing conditions can alter quality attributes including bioactive compound content. This study evaluated the stability of bioactive compounds in Butia pulp upon pasteurization, during 12 months of frozen storage, and in Butia nectar after a 3-month storage period. Pulp pasteurization resulted in a reduction in phenolic, flavonoid, carotenoid, and ascorbic acid contents. After a 12-month frozen storage period, flavonoid, phenolic, and ascorbic acid contents decreased while carotenoid content remained unaltered. Carotenoid, ascorbic acid, and phenolic contents were unaffected by the 3-month storage of Butia nectar; however, flavonoid content and antioxidant potential were reduced. Despite bioactive compound degradation upon heat treatment and storage, Butia nectar remained rich in phenolics, especially (−)-epicatechin, rutin, and (+)-catechin.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination.
    Journal of agricultural and food chemistry, 2017
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capao do Leao, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geog...

  • Probiotic butiá (Butia odorata) ice cream: Development, characterization, stability of bioactive compounds, and viability of Bifidobacterium lactis during storage
    LWT, 2017
    Co-Authors: Claudio Eduardo Dos Santos Cruxen, Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Cesar Valmor Rombaldi, Ângela Maria Fiorentini, Fábio Clasen Chaves
    Abstract:

    Abstract The addition of fruit with bioactive properties such as Butia odorata , henceforth called Butia, and probiotic bacteria may improve the nutritional and functional value of ice cream. In this study, Butia ice cream supplemented with Bifidobacterium lactis (Bl-04) was developed and characterized. Butia ice cream showed 71.2 g 100 g −1 of overrun, a density of 575 g cm −3 , and a pH of 4.7. During 90 days of frozen storage (−18 °C), a 10% reduction in total phenolic content and a 5% reduction in l -ascorbic acid content were observed. Carotenoids and flavonoids increased during frozen storage. Probiotic bacteria B . lactis (Bl-04) remained viable (above 10 6  CFU g −1 ) in Butia ice cream during storage, confirming the probiotic characteristic of the product. Sensory analyses showed that Butia ice cream had high acceptability (6.8–7.8) and purchase intent (above 80%). The combination of B . lactis and Butia fruit attributed functional characteristics to the ice cream.

  • Butia spp. (Arecaceae) LC-MS-Based Metabolomics for Species and Geographical Origin Discrimination
    2016
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Ivan Ricardo Carvalho, Fábio Clasen Chaves
    Abstract:

    The metabolic variability of fruit from Butia spp. (Arecaceae) genotypes from different geographical locations was characterized using untargeted metabolomics by liquid chromatography–mass spectrometry (LC-MS) followed by multivariate data analyses. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) from LC-MS data sets showed a clear distinction among Butia catarinensis, Butia odorata, Butia paraguayensis, and Butia yatay. The major metabolites that contributed to species discrimination were primary metabolites including sugars and organic acids and specialized metabolites such as tetrahydroxy-trans-stilbene and rutin. B. odorata fruit from Tapes, RS, Brazil, showed a high content of organic acids and flavonoids, whereas B. odorata fruits from Capão do Leão, RS, Brazil, showed a high sugar content. The results demonstrate that LC-ESI-qToF-MS-based metabolic profiling coupled with chemometric analysis can be used to discriminate among Butia species and between geographical origins of B. odorata and to identify primary and specialized metabolites responsible for the discrimination

  • Butia spp. (Arecaceae): An overview
    Scientia Horticulturae, 2014
    Co-Authors: Jessica Fernanda Hoffmann, Rosa Lia Barbieri, Cesar Valmor Rombaldi, Fábio Clasen Chaves
    Abstract:

    Butia is a genus of palms (Arecaceae), autochthonous to South America with great potential for income generation. In order to better utilize and maintain the currently available genetic resources, it is necessary to pursue studies directed towards the taxonomic and systematic characterization (morphological, phenotypic, molecular, chemical, and reproductive) and conservation of Butia spp. Despite the long use of this plant, a limited number of scientific studies and publications are available on Butia spp., with a significant proportion of the literature written in Portuguese. This review intends to compile all the available information on the genus, covering several aspects of the plant and its potential applications.

Rafael Guerra Lund - One of the best experts on this subject based on the ideXlab platform.

  • Development and properties of endodontic resin sealers with natural oils.
    Journal of dentistry, 2020
    Co-Authors: Cristiane M. Reiznautt, Juliana Silva Ribeiro, Everton Kreps, Wellington Luiz De Oliveira Da Rosa, Hellen De Lacerda, Sonia Luque Peralta, Marco C. Bottino, Rafael Guerra Lund
    Abstract:

    Abstract Objectives To synthesize and evaluate the physicochemical, antimicrobial, and cytocompatibility properties of experimental resin-based endodontic sealers containing Butia or copaiba natural oils. Methods Experimental groups contained Butia (Butia capitata) at 0.5 % (B0.5), 1 % (B1), 2 % (B2), and copaiba (Copaifera spp.) at 0.5 % (C0.5), 1 % (C1), and 2 % (C2). The control group contained no added oils (experimental material, EM) and the commercial group was a methacrylate-based resin material (RealSeal™, SybronEndo Corporation, Orange, CA, USA). Degree of conversion, film thickness, setting time, flow, water sorption and solubility, and radiopacity were measured. Meanwhile, antimicrobial (modified direct contact test) and cytotoxicity assays of the experimental groups and controls were performed. One-way ANOVA was used to determine the effect of the independent variable (material) on the degree of conversion, film thickness, radiopacity, flow, setting time, water sorption and solubility, and cytotoxicity. For antimicrobial assays, data were analyzed using two-way ANOVA and Ŝidak’s test. Results The experimental groups containing natural oils showed higher values of degree of conversion, and lowest water sorption and solubility. EM, B0.5, B1, B2, and RS showed similar film thicknesses. The flow values were statistically similar in all groups. The experimental groups showed adequate cell compatibility. Copaiba oil at 2% increased the antimicrobial effect after 1 and 24 h (p Conclusion Novel resin sealers containing natural oils are a promising alternative for endodontics, because of their good physicochemical properties, antimicrobial effects, and cytocompatibility when compared to a commercially available sealer. Clinical significance Endodontic sealers containing Butia or copaiba had satisfactory cytocompatibility, antimicrobial effects, and adequate physicochemical properties.

  • The Phytochemistry and Pharmacology of Butia sp.: A Systematic Review and an Overview of the Technological Monitoring Process
    Phytotherapy research : PTR, 2017
    Co-Authors: Lara Rodrigues Schneider, Daniela Coelho Dos Santos, Angela Diniz Campos, Rafael Guerra Lund
    Abstract:

    The Butia sp. are native South America trees, whose fruits are consumed in natura and have significant biological properties; however, trees of this genus plant are in danger of extinction. A systematic review of the literature and a technological overview were carried out to summarize the available evidence on the therapeutic uses and the phytochemical compounds of Butia sp. The following electronic databases were researched: MedLine (PubMed), Web of Science, Scopus, Scielo, and the gray literature. Furthermore, the online system such as the US Patent and Trademark Office, Espacenet, National Institute of Industrial Property, and Google Patents were accessed to obtain patent data. The inclusion criteria were articles that describe either the therapeutic uses of Butia sp. (antimicrobial activity, antioxidant activity, anti-inflammatory activity, antineoplastic activity) or studies describing phytochemical compounds of Butia sp. A limited amount of manual search was also undertaken. Reference lists were scanned to identify other relevant studies, and requests for unpublished data were conducted to people working in the field. Among 12 papers and 14 patents, 9 complete texts of scientific articles and 1 patent were scrutinised by two reviewers. We concluded that Butia has shown some antioxidant, anti-inflammatory, and antimicrobial activity, and its use could have important implications for future therapeutic uses. Although there is evidence of pharmacological potential from in vitro studies, clinical studies must be conducted to confirm the effectiveness of Butia sp. The evidence of its therapeutic uses has not been extensively studied yet, and the available evidence still needs further confirmation. Copyright © 2017 John Wiley & Sons, Ltd.