The Experts below are selected from a list of 66 Experts worldwide ranked by ideXlab platform
Joseph D. Rosen - One of the best experts on this subject based on the ideXlab platform.
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Photolysis of two pesticides used by organic farmers : Sabadilla and Ryania
2007Co-Authors: Joseph D. Rosen, Xuejun ZangAbstract:Solar irradiation of the major components of the "organic" pesticides sabadilla and ryania was studied in aqueous solution. One of the sabadilla components, veratridine, degraded slowly when exposed to sunlight. Another sabadilla component, Cevadine, was stable. The major components of ryania (ryanodine and dehydroryanodine) also decomposed slowly in sunlight. The major products resulted from photohydrolysis.
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Multiresidue Analytical Procedure for Insecticides Used by Organic Farmers
Journal of Agricultural and Food Chemistry, 1998Co-Authors: Xuejun Zang, Elaine K. Fukuda, Joseph D. RosenAbstract:A multiresidue procedure for the insecticides used by organic farmers has been developed. Rotenone, Cevadine, and veratridine (the major components of sabadilla), pyrethrin I and pyrethrin II (the major components of pyrethrum), and ryanodine and dehydroryanodine (the major components of ryania) can be separated by high-performance liquid chromatography (HPLC) and detected and quantified by atmospheric pressure chemical ionization mass spectrometry (APCI/MS) in the selected ion monitoring mode. Piperonyl butoxide, a material sometimes used together with rotenone or pyrethrum to enhance toxicity, can also be detected and quantified by this procedure. The analytes are extracted with acetonitrile/water and are cleaned up with a C18 solid-phase extraction cartridge. Rotenone, piperonyl butoxide, and the two major sabadilla components could be detected (signal-to-noise ratio = 10) in lettuce, cucumber, and cabbage at 1−6 ppb. Pyrethrin I and the ryania components could be detected between 10 and 171 ppb in the...
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Method for the determination of veratridine and Cevadine, major components of the natural insecticide sabadilla, in lettuce and cucumbers
Journal of Agricultural and Food Chemistry, 1997Co-Authors: Xuejun Zang, Elaine K. Fukuda, Joseph D. RosenAbstract:Sabadilla, an insecticide widely used by organic farmers, can be separated into five of its components (veratridine, Cevadine, cevine, cevacine, and sabadine) by high-performance liquid chromatogra...
Xuejun Zang - One of the best experts on this subject based on the ideXlab platform.
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Photolysis of two pesticides used by organic farmers : Sabadilla and Ryania
2007Co-Authors: Joseph D. Rosen, Xuejun ZangAbstract:Solar irradiation of the major components of the "organic" pesticides sabadilla and ryania was studied in aqueous solution. One of the sabadilla components, veratridine, degraded slowly when exposed to sunlight. Another sabadilla component, Cevadine, was stable. The major components of ryania (ryanodine and dehydroryanodine) also decomposed slowly in sunlight. The major products resulted from photohydrolysis.
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Multiresidue Analytical Procedure for Insecticides Used by Organic Farmers
Journal of Agricultural and Food Chemistry, 1998Co-Authors: Xuejun Zang, Elaine K. Fukuda, Joseph D. RosenAbstract:A multiresidue procedure for the insecticides used by organic farmers has been developed. Rotenone, Cevadine, and veratridine (the major components of sabadilla), pyrethrin I and pyrethrin II (the major components of pyrethrum), and ryanodine and dehydroryanodine (the major components of ryania) can be separated by high-performance liquid chromatography (HPLC) and detected and quantified by atmospheric pressure chemical ionization mass spectrometry (APCI/MS) in the selected ion monitoring mode. Piperonyl butoxide, a material sometimes used together with rotenone or pyrethrum to enhance toxicity, can also be detected and quantified by this procedure. The analytes are extracted with acetonitrile/water and are cleaned up with a C18 solid-phase extraction cartridge. Rotenone, piperonyl butoxide, and the two major sabadilla components could be detected (signal-to-noise ratio = 10) in lettuce, cucumber, and cabbage at 1−6 ppb. Pyrethrin I and the ryania components could be detected between 10 and 171 ppb in the...
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Method for the determination of veratridine and Cevadine, major components of the natural insecticide sabadilla, in lettuce and cucumbers
Journal of Agricultural and Food Chemistry, 1997Co-Authors: Xuejun Zang, Elaine K. Fukuda, Joseph D. RosenAbstract:Sabadilla, an insecticide widely used by organic farmers, can be separated into five of its components (veratridine, Cevadine, cevine, cevacine, and sabadine) by high-performance liquid chromatogra...
Bin Hu - One of the best experts on this subject based on the ideXlab platform.
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global detection and semi quantification of fritillaria alkaloids in fritillariae ussuriensis bulbus by a non targeted multiple reaction monitoring approach
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Li Wang, Sibao Chen, Puikin So, Ping Li, Bin HuAbstract:: Methods based on triple quadrupole tandem mass spectrometry have been widely used and reported as highly selective and sensitive methods for quantifying substances of herbal medicines. However, most of them were limited to targeted components, due to the difficulties to optimize the multiple reaction monitoring transitions without authentic standards. This study proposed a novel strategy for non-targeted optimization of multiple reaction monitoring method based on the diagnostic ion guided family classifications, tandem mass spectrometry database establishment, and transitions and collision energy screening. Applying this strategy, 59 Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus have been classified, and 51 of these Fritillaria alkaloids were successfully detected by the optimal multiple reaction monitoring method. For semi-quantification, the easy-to-obtain Fritillaria alkaloids of each type, such as verticinone for cevanine type and peimisine for jervine type, were used as the reference standards to calibrate the other Fritillaria alkaloids in the same type. The method was demonstrated a good linearity (R(2) > 0.998) with satisfactory accuracy and precision, and the lower limits of quantification of verticinone and peimisine were estimated to be 0.076 and 0.216 pg, respectively. In addition, the results suggested that the proposed strategy might obtained high quality metabolomics data in discrimination of Fritillaria unibracteata and Fritillaria ussuriensis.
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Global detection and semi‐quantification of Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus by a non‐targeted multiple reaction monitoring approach
IEEE Journal of Solid-state Circuits, 2015Co-Authors: Li Wang, Sibao Chen, Puikin So, Ping Li, Bin HuAbstract:: Methods based on triple quadrupole tandem mass spectrometry have been widely used and reported as highly selective and sensitive methods for quantifying substances of herbal medicines. However, most of them were limited to targeted components, due to the difficulties to optimize the multiple reaction monitoring transitions without authentic standards. This study proposed a novel strategy for non-targeted optimization of multiple reaction monitoring method based on the diagnostic ion guided family classifications, tandem mass spectrometry database establishment, and transitions and collision energy screening. Applying this strategy, 59 Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus have been classified, and 51 of these Fritillaria alkaloids were successfully detected by the optimal multiple reaction monitoring method. For semi-quantification, the easy-to-obtain Fritillaria alkaloids of each type, such as verticinone for cevanine type and peimisine for jervine type, were used as the reference standards to calibrate the other Fritillaria alkaloids in the same type. The method was demonstrated a good linearity (R(2) > 0.998) with satisfactory accuracy and precision, and the lower limits of quantification of verticinone and peimisine were estimated to be 0.076 and 0.216 pg, respectively. In addition, the results suggested that the proposed strategy might obtained high quality metabolomics data in discrimination of Fritillaria unibracteata and Fritillaria ussuriensis.
Gilbert Pépin - One of the best experts on this subject based on the ideXlab platform.
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LC-EI-MS Determination of Veratridine and Cevadine in Two Fatal Cases of Veratrum album Poisoning
Journal of analytical toxicology, 2001Co-Authors: Yvan Gaillard, Gilbert PépinAbstract:We report two fatal poisonings due to the ingestion of plant material. The two deceased were discovered in the water of a mountain lake about one month after the postmortem immersion of the corpses. Macroscopic examination of the stomachs revealed the presence of a very large number of small blackish granules, which were later identified as seeds of a Veratrum species. Veratridine and Cevadine were identified and quantitated by high-performance liquid chromatography-electrospray ionization-mass spectrometry. Measured blood concentrations were 0.17 and 0.40 ng/mL for veratridine and 0.32 and 0.48 ng/mL for Cevadine. The absence of other toxic substance led to the assumption that this massive ingestion was the cause of death, although the circumstances surrounding intake remained unknown.
J. Daniel Hare - One of the best experts on this subject based on the ideXlab platform.
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Purification and quantitative analysis of veratridine and Cevadine by HPLC
Journal of Agricultural and Food Chemistry, 1996Co-Authors: J. Daniel HareAbstract:As part of a study to determine the variation in the effectiveness of commercial pesticide formulations of ester steroidal alkaloids from sabadilla (Schoenocaulon officinale Grey) seeds in the integrated pest management of citrus, a method to isolate and measure large quantities of alkaloids from natural starting materials was needed. The addition of the solvent modifier sodium dodecyl sulfate (SDS) to a previously published HPLC method greatly improved peak resolution by minimizing peak tailing. The use of the non-ester alkaloid papaverine as an internal standard permitted quantification of sabadilla alkaloids by HPLC, and this modified method was then used to monitor the breakdown of Cevadine and veratridine, the two most abundant sabadilla alkaloids, in aqueous solutions as a function of time and pH.