The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
John Meurig Thomas - One of the best experts on this subject based on the ideXlab platform.
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max perutz Chemist molecular biologist human rights activist
Notes and Records, 2006Co-Authors: John Meurig ThomasAbstract:Tribute paid to Max Perutz before the Max Perutz Memorial Lecture given by Professor Sari Nusseibeh at The International Human Rights Network of Academics and Scholarly Societies, The Royal Society...
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max perutz Chemist molecular biologist human rights activist
Chemical Communications, 2005Co-Authors: John Meurig ThomasAbstract:Tribute paid to Max Perutz prior to the Max Perutz Memorial Lecture given by Professor Sari Nusseibeh at The International Human Rights Network of Academics and Scholarly Societies, Royal Society, London, 19 May 2005.
Stanley S Young - One of the best experts on this subject based on the ideXlab platform.
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powermv a software environment for molecular viewing descriptor generation data analysis and hit evaluation
Journal of Chemical Information and Modeling, 2005Co-Authors: Kejun Liu, Jun Feng, Stanley S YoungAbstract:Ideally, a team of biologists, medicinal Chemists and information specialists will evaluate the hits from high throughput screening. In practice, it often falls to nonmedicinal Chemists to make the initial evaluation of HTS hits. Chemical genetics and high content screening both rely on screening in cells or animals where the biological target may not be known. There is a need to place active compounds into a context to suggest potential biological mechanisms. Our idea is to build an operating environment to help the biologist make the initial evaluation of HTS data. To this end the operating environment provides viewing of compound structure files, computation of basic biologically relevant chemical properties and searching against biologically annotated chemical structure databases. The benefit is to help the nonmedicinal Chemist, biologist and statistician put compounds into a potentially informative biological context. Although there are several similar public and private programs used in the pharmaceutical industry to help evaluate hits, these programs are often built for computational Chemists. Our program is designed for use by biologists and statisticians.
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powermv a software environment for molecular viewing descriptor generation data analysis and hit evaluation
Journal of Chemical Information and Modeling, 2005Co-Authors: Jun Feng, Stanley S YoungAbstract:Ideally, a team of biologists, medicinal Chemists and information specialists will evaluate the hits from high throughput screening. In practice, it often falls to nonmedicinal Chemists to make the initial evaluation of HTS hits. Chemical genetics and high content screening both rely on screening in cells or animals where the biological target may not be known. There is a need to place active compounds into a context to suggest potential biological mechanisms. Our idea is to build an operating environment to help the biologist make the initial evaluation of HTS data. To this end the operating environment provides viewing of compound structure files, computation of basic biologically relevant chemical properties and searching against biologically annotated chemical structure databases. The benefit is to help the nonmedicinal Chemist, biologist and statistician put compounds into a potentially informative biological context. Although there are several similar public and private programs used in the pharmace...
Jun Feng - One of the best experts on this subject based on the ideXlab platform.
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powermv a software environment for molecular viewing descriptor generation data analysis and hit evaluation
Journal of Chemical Information and Modeling, 2005Co-Authors: Kejun Liu, Jun Feng, Stanley S YoungAbstract:Ideally, a team of biologists, medicinal Chemists and information specialists will evaluate the hits from high throughput screening. In practice, it often falls to nonmedicinal Chemists to make the initial evaluation of HTS hits. Chemical genetics and high content screening both rely on screening in cells or animals where the biological target may not be known. There is a need to place active compounds into a context to suggest potential biological mechanisms. Our idea is to build an operating environment to help the biologist make the initial evaluation of HTS data. To this end the operating environment provides viewing of compound structure files, computation of basic biologically relevant chemical properties and searching against biologically annotated chemical structure databases. The benefit is to help the nonmedicinal Chemist, biologist and statistician put compounds into a potentially informative biological context. Although there are several similar public and private programs used in the pharmaceutical industry to help evaluate hits, these programs are often built for computational Chemists. Our program is designed for use by biologists and statisticians.
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powermv a software environment for molecular viewing descriptor generation data analysis and hit evaluation
Journal of Chemical Information and Modeling, 2005Co-Authors: Jun Feng, Stanley S YoungAbstract:Ideally, a team of biologists, medicinal Chemists and information specialists will evaluate the hits from high throughput screening. In practice, it often falls to nonmedicinal Chemists to make the initial evaluation of HTS hits. Chemical genetics and high content screening both rely on screening in cells or animals where the biological target may not be known. There is a need to place active compounds into a context to suggest potential biological mechanisms. Our idea is to build an operating environment to help the biologist make the initial evaluation of HTS data. To this end the operating environment provides viewing of compound structure files, computation of basic biologically relevant chemical properties and searching against biologically annotated chemical structure databases. The benefit is to help the nonmedicinal Chemist, biologist and statistician put compounds into a potentially informative biological context. Although there are several similar public and private programs used in the pharmace...
Charles L Mccormick - One of the best experts on this subject based on the ideXlab platform.
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reversible addition fragmentation chain transfer raft radical polymerization and the synthesis of water soluble co polymers under homogeneous conditions in organic and aqueous media
Progress in Polymer Science, 2007Co-Authors: Andrew B Lowe, Charles L MccormickAbstract:Abstract Reversible addition–fragmentation chain transfer (RAFT) radical polymerization has, since its discovery by CSIRO, evolved into an extremely powerful synthetic tool for polymer Chemists. The versatility of RAFT, with respect to reaction conditions and monomer class, now facilitates the preparation of materials which, only 10 years ago, could not be prepared with well-defined molecular characteristics. One particularly advantageous feature of RAFT is its applicability to the synthesis of water-soluble (co)polymers both directly in aqueous media under homogeneous conditions as well as in organic media. The ease of access to an almost infinite number of RAFT mediating agents now affords the synthetic Chemist the ability to polymerize virtually any activated, and some non-activated, water-soluble/hydrophilic monomers. We highlight herein the application of RAFT to the synthesis of water-soluble/dispersible (co)polymers under homogeneous reaction conditions in both aqueous and organic media. Additionally, we review the aqueous solution properties of advanced stimuli–responsive systems with a particular emphasis on the stimulus-induced, and often reversible, supramolecular self-assembly characteristics of the materials. Limitations of homogeneous aqueous RAFT are also highlighted.
Kejun Liu - One of the best experts on this subject based on the ideXlab platform.
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powermv a software environment for molecular viewing descriptor generation data analysis and hit evaluation
Journal of Chemical Information and Modeling, 2005Co-Authors: Kejun Liu, Jun Feng, Stanley S YoungAbstract:Ideally, a team of biologists, medicinal Chemists and information specialists will evaluate the hits from high throughput screening. In practice, it often falls to nonmedicinal Chemists to make the initial evaluation of HTS hits. Chemical genetics and high content screening both rely on screening in cells or animals where the biological target may not be known. There is a need to place active compounds into a context to suggest potential biological mechanisms. Our idea is to build an operating environment to help the biologist make the initial evaluation of HTS data. To this end the operating environment provides viewing of compound structure files, computation of basic biologically relevant chemical properties and searching against biologically annotated chemical structure databases. The benefit is to help the nonmedicinal Chemist, biologist and statistician put compounds into a potentially informative biological context. Although there are several similar public and private programs used in the pharmaceutical industry to help evaluate hits, these programs are often built for computational Chemists. Our program is designed for use by biologists and statisticians.
