The Experts below are selected from a list of 31215 Experts worldwide ranked by ideXlab platform
Hunter H Handsfield - One of the best experts on this subject based on the ideXlab platform.
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patient delivered partner treatment with azithromycin to prevent repeated Chlamydia Trachomatis infection among women a randomized controlled trial
Sexually Transmitted Diseases, 2003Co-Authors: Julia A Schillinger, William L H Whittington, Charlotte K Kent, Patricia Kissinger, Helene Calvet, Ray L Ransom, Maya Sternberg, Stuart M Berman, David H Martin, Hunter H HandsfieldAbstract:BackgroundRepeated infection with Chlamydia Trachomatis increases the risk for serious sequelae: pelvic inflammatory disease, ectopic pregnancy, infertility, and chronic pelvic pain. A substantial proportion of women treated for C Trachomatis infection are reinfected by an untreated male sex partner
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community based urine screening for Chlamydia Trachomatis with a ligase chain reaction assay
Annals of Internal Medicine, 1997Co-Authors: Jeanne M Marrazzo, Walter E Stamm, Christine L White, Barbara Krekeler, Connie Celum, William E Lafferty, Hunter H HandsfieldAbstract:Background: Urine tests for Chlamydia Trachomatis permit expansion of screening beyond traditional clinic environments. Prevention of infection in teenagers is a high priority. Objective: To define...
Sheila K West - One of the best experts on this subject based on the ideXlab platform.
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ocular Chlamydia Trachomatis infection elimination with mass drug administration
Expert Review of Anti-infective Therapy, 2019Co-Authors: Meraf A Wolle, Sheila K WestAbstract:Introduction: Ocular Chlamydia Trachomatis infection, the causative agent for trachoma, is responsible for 1.9 million cases of visual loss worldwide. Mass Drug Administration (MDA) with azithromyc...
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stability of Chlamydia Trachomatis on storage of dry swabs for accurate detection by nucleic acid amplification tests
Journal of Clinical Microbiology, 2015Co-Authors: Laura Dize, Thomas C Quinn, Charlotte A Gaydos, Sheila K WestAbstract:Trachoma, caused by repeated ocular infections with Chlamydia Trachomatis is the primary cause for infectious blindness throughout the world and predominately affects individuals in resource-poor countries ([1][1]). Operational research on trachoma involves not only clinical trachoma grading methods
B De Barbeyrac - One of the best experts on this subject based on the ideXlab platform.
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First case of Chlamydia Trachomatis L2b proctitis in a woman
Clinical Microbiology and Infection, 2011Co-Authors: O. Peuchant, C. Baldit, C. Le Roy, S. Trombert-paolantoni, M. Clerc, C. Bébéar, B De BarbeyracAbstract:Since 2003, outbreaks of lymphogranuloma venereum (LGV) have been reported in European countries, North America, and Australia. Current LGV cases have been caused by Chlamydia Trachomatis serovar L2. This sexually transmitted infection is predominantly found among men who have sex with men, specifically men who are seropositive for human immunodeficiency virus and have clinical signs of proctitis. The current outbreak has been almost exclusively attributed to a new variant, designated L2b. Although urogenital cases of LGV have been described in the heterosexual population, we report the first case of C. Trachomatis L2b proctitis in a woman.
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genital Chlamydia Trachomatis infections
Clinical Microbiology and Infection, 2009Co-Authors: C. Bébéar, B De BarbeyracAbstract:Chlamydia Trachomatis infections affect young, sexually active persons. Risk factors include multiple partners and failure to use condoms. The incidence of infection has increased in the past 10 years. Untreated C. Trachomatis infections are responsible for a large proportion of salpingitis, ectopic pregnancy, infertility and, to a lesser extent, epididymitis. Screening is a possible intervention to control the infection, which is often asymptomatic. The emergence of lymphogranuloma venereum proctitis in men who have sex with men, in Europe, and of a variant with a deletion in the cryptic plasmid, in Sweden, are new features of C. Trachomatis infections in the last years. A diagnosis is best made by using nucleic acid amplification tests, because they perform well and do not require invasive procedures for specimen collection. Single-dose therapy has been a significant development for treatment of an uncomplicated infection of the patient and his or her sexual partner.
William J. Ledger - One of the best experts on this subject based on the ideXlab platform.
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Detection of Chlamydia Trachomatis by the polymerase chain reaction in the cervices of women with acute salpingitis.
American Journal of Obstetrics and Gynecology, 1993Co-Authors: Steven S. Witkin, Jan Jeremias, Miklós Tóth, William J. LedgerAbstract:OBJECTIVE: Our objective was to determine whether an increased prevalence of Chlamydia Trachomatis could be detected by the polymerase chain reaction as opposed to culture in the cervices of women with acute salpingitis. STUDY DESIGN: Endocervical samples from 15 women with laparoscopy-verified acute salpingitis and 20 women seeking medical help for conditions other than pelvic pain were tested for Chlamydia Trachomatis with the polymerase chain reaction. The oligonucleotide primer pairs used were specific for a 144 bp region of the major outer membrane protein that contained a single Eco RI endonuclease cleavage site. The detection of a 144 bp band that was cleaved by Eco RI to a 103 bp band denoted a Chlamydia Trachomatis -positive sample. Cervical samples were cultured for Chlamydia Trachomatis with the use of McCoy cells. The lymphocyte proliferative response to Chlamydia Trachomatis elementary bodies was also determined. RESULTS: Nine of the 15 women (60%) with salpingitis had positive results when tested with the polymerase chain reaction for cervical Chlamydia Trachomatis . Only two of these women (13%), both of whom had positive results when tested with the polymerase chain reaction, had cultures that were positive for Chlamydia Trachomatis ( p Chlamydia . Those women plus two women with unexplained recurrent abortions had positive polymerase chain reaction test results for Chlamydia Trachomatis . A lymphocyte proliferative response to Chlamydia Trachomatis was detected in five of eight women with salpingitis, as well as three of the other four patients, all of whom had positive polymerase chain reaction test results; lymphocytes from the remaining women were unresponsive. Follow-up cervical samples were obtained 4 to 6 months after treatment from six of the patients with salpingitis who had positive polymerase chain reaction test results; at that time five had negative polymerase chain reaction test results for Chlamydia Trachomatis . CONCLUSION: The polymerase chain reaction appeared to be more sensitive and more rapid than culture in detecting Chlamydia Trachomatis in the cervices of women with acute salpingitis. This assay may be of value for the early diagnosis of Chlamydial infections.
Marschalkó Márta - One of the best experts on this subject based on the ideXlab platform.
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Conjunctivitis gonorrhoica szövődése Chlamydia Trachomatis -infekcióval | Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia Trachomatis coinfection
'Akademiai Kiado Zrt.', 2033Co-Authors: Árvai Mariann, Ostorházi Eszter, Mihalik Noémi, Kárpáti Sarolta, Marschalkó MártaAbstract:A keratoconjunctivitis gonorrhoica ritka, a Neisseria gonorrhoeae által okozott gennyes váladékozással kísért kötőhártya-gyulladás, amelyet felnőtteknél a szembe kerülő fertőző váladék okozhat. A Chlamydia Trachomatis D-K szerotípusa által okozott conjunctivitis felnőttkori formáját nemi váladékok szembe kerülésével létrejött, kétoldali mucopurulens váladékozással kísért gyulladás jellemzi. A szerzők egy 33 éves, syphilis latens tarda miatt gondozott férfi beteg esetét ismertetik, akinek a hetek óta fennálló purulens conjunctivitise hátterében a mikrobiológiai vizsgálatok során Chlamydia Trachomatis-fertőzéssel kombinált Neisseria gonorrhoeae-infekció igazolódott. A tenyésztéses és PCR-vizsgálatok során a pharynxból is kimutatható volt mindkét kórokozó. A betegnek sem urológiai, sem felső légúti tünetei nem voltak. A fertőződés kábítószer hatása alatt történt szexuális abúzust követően alakult ki. A parenteralis, majd per os cephalosporin- és azithromycinterápia hatására három hét alatt teljes remisszió következett be. Orv. Hetil., 2013, 154, 834–837. | Gonococcal conjunctivitis is a rare infection induced by Neisseria gonorrhoeae and it usually manifests as a hyperacute purulent conjunctivitis. Ocular access of the infectious secretion during sexual intercourse is the way of transmission among adults. Inclusion conjunctivitis caused by the serovars D-K of Chlamydia Trachomatis also affects the sexually active population. Authors present a case of a 33-year-old homosexual man who was treated for late latent syphilis formerly. Clinical symptoms were yellow purulent discharge for 3 weeks without any urological or upper respiratory tract symptoms. Conjunctival Neisseria gonorrhoeae and Chlamydia Trachomatis infection was identified using cultures and polymerase chain reaction; pharyngeal swab culture and polymerase chain reaction showed positive results for both pathogens. The patient was probably under influence of party drugs at the time of sexual abuse when he became infected. After parenteral and oral cephalosporin and azithomycin therapy the patient had complete recovery within three weeks. Orv. Hetil., 2013, 154, 834–837
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Conjunctivitis gonorrhoica szövődése Chlamydia Trachomatis-infekcióval [Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia Trachomatis coinfection]
'Akademiai Kiado Zrt.', 2014Co-Authors: Arvai M, Ostorházi Eszter, Mihalik Noémi, Kárpáti Sarolta, Marschalkó MártaAbstract:Gonococcal conjunctivitis is a rare infection induced by Neisseria gonorrhoeae and it usually manifests as a hyperacute purulent conjunctivitis. Ocular access of the infectious secretion during sexual intercourse is the way of transmission among adults. Inclusion conjunctivitis caused by the serovars D-K of Chlamydia Trachomatis also affects the sexually active population. Authors present a case of a 33-year-old homosexual man who was treated for late latent syphilis formerly. Clinical symptoms were yellow purulent discharge for 3 weeks without any urological or upper respiratory tract symptoms. Conjunctival Neisseria gonorrhoeae and Chlamydia Trachomatis infection was identified using cultures and polymerase chain reaction; pharyngeal swab culture and polymerase chain reaction showed positive results for both pathogens. The patient was probably under influence of party drugs at the time of sexual abuse when he became infected. After parenteral and oral cephalosporin and azithromycin therapy the patient had complete recovery within three weeks