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Nicholas J. Talley - One of the best experts on this subject based on the ideXlab platform.

  • cumulative incidence of Chronic Constipation a population based study 1988 2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Cumulative incidence of Chronic Constipation: a population-based study 1988–2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Risk factors for Chronic Constipation and a possible role of analgesics
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2007
    Co-Authors: Joseph Y. Chang, Cathy D. Schleck, Alan R. Zinsmeister, G. Richard Locke, Nicholas J. Talley
    Abstract:

    Abstract  Constipation has an estimated prevalence of 15% in the general population. However, the etiopathogenesis of this condition remains relatively obscure. This study sought to identify potentially novel risk factors for Chronic Constipation. A valid self-report questionnaire was mailed to an age- and gender-stratified random sample of Olmsted County, Minnesota residents aged 30–64 years. A logistic regression model that adjusted for age, gender and somatic symptom score (SSC) was used to identify factors associated with Chronic Constipation. People reporting symptoms of irritable bowel syndrome (IBS) were excluded. Of the 892 eligible subjects, 653 (73%) returned the survey. Among the 523 subjects not reporting IBS symptoms, Chronic Constipation was reported by 93 (18%) of the respondents. Chronic Constipation was significantly associated with use of acetaminophen [≥7 tablets per week, OR = 2.7 (1.1–6.6)]; aspirin [OR = 1.7 (1.0–2.7)]; non-steroidal anti-inflammatory drugs [OR = 1.8 (1.1–3.0)]; and SSC. No association was detected for age, gender, body mass index, marital status, smoking, alcohol, coffee, education level, food allergy, exposure to pets, stress, emotional support, or water supply. Chronic Constipation is associated with use of acetaminophen, aspirin and non-steroidal anti-inflammatory drugs. The explanation of these associations requires further investigation.

  • Management of Chronic Constipation.
    Reviews in gastroenterological disorders, 2004
    Co-Authors: Nicholas J. Talley
    Abstract:

    Constipation is a common problem in the United States. Although most individuals do not seek health care for its symptoms, there are still more than 2 million visits to physicians annually for treatment. In this article, the author presents an overview of current diagnostic tools and treatment options for Chronic Constipation.

R. S. Choung - One of the best experts on this subject based on the ideXlab platform.

  • cumulative incidence of Chronic Constipation a population based study 1988 2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Cumulative incidence of Chronic Constipation: a population-based study 1988–2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

Alan R. Zinsmeister - One of the best experts on this subject based on the ideXlab platform.

  • cumulative incidence of Chronic Constipation a population based study 1988 2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Cumulative incidence of Chronic Constipation: a population-based study 1988–2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Risk factors for Chronic Constipation and a possible role of analgesics
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2007
    Co-Authors: Joseph Y. Chang, Cathy D. Schleck, Alan R. Zinsmeister, G. Richard Locke, Nicholas J. Talley
    Abstract:

    Abstract  Constipation has an estimated prevalence of 15% in the general population. However, the etiopathogenesis of this condition remains relatively obscure. This study sought to identify potentially novel risk factors for Chronic Constipation. A valid self-report questionnaire was mailed to an age- and gender-stratified random sample of Olmsted County, Minnesota residents aged 30–64 years. A logistic regression model that adjusted for age, gender and somatic symptom score (SSC) was used to identify factors associated with Chronic Constipation. People reporting symptoms of irritable bowel syndrome (IBS) were excluded. Of the 892 eligible subjects, 653 (73%) returned the survey. Among the 523 subjects not reporting IBS symptoms, Chronic Constipation was reported by 93 (18%) of the respondents. Chronic Constipation was significantly associated with use of acetaminophen [≥7 tablets per week, OR = 2.7 (1.1–6.6)]; aspirin [OR = 1.7 (1.0–2.7)]; non-steroidal anti-inflammatory drugs [OR = 1.8 (1.1–3.0)]; and SSC. No association was detected for age, gender, body mass index, marital status, smoking, alcohol, coffee, education level, food allergy, exposure to pets, stress, emotional support, or water supply. Chronic Constipation is associated with use of acetaminophen, aspirin and non-steroidal anti-inflammatory drugs. The explanation of these associations requires further investigation.

Cathy D. Schleck - One of the best experts on this subject based on the ideXlab platform.

  • cumulative incidence of Chronic Constipation a population based study 1988 2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Cumulative incidence of Chronic Constipation: a population-based study 1988–2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Risk factors for Chronic Constipation and a possible role of analgesics
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2007
    Co-Authors: Joseph Y. Chang, Cathy D. Schleck, Alan R. Zinsmeister, G. Richard Locke, Nicholas J. Talley
    Abstract:

    Abstract  Constipation has an estimated prevalence of 15% in the general population. However, the etiopathogenesis of this condition remains relatively obscure. This study sought to identify potentially novel risk factors for Chronic Constipation. A valid self-report questionnaire was mailed to an age- and gender-stratified random sample of Olmsted County, Minnesota residents aged 30–64 years. A logistic regression model that adjusted for age, gender and somatic symptom score (SSC) was used to identify factors associated with Chronic Constipation. People reporting symptoms of irritable bowel syndrome (IBS) were excluded. Of the 892 eligible subjects, 653 (73%) returned the survey. Among the 523 subjects not reporting IBS symptoms, Chronic Constipation was reported by 93 (18%) of the respondents. Chronic Constipation was significantly associated with use of acetaminophen [≥7 tablets per week, OR = 2.7 (1.1–6.6)]; aspirin [OR = 1.7 (1.0–2.7)]; non-steroidal anti-inflammatory drugs [OR = 1.8 (1.1–3.0)]; and SSC. No association was detected for age, gender, body mass index, marital status, smoking, alcohol, coffee, education level, food allergy, exposure to pets, stress, emotional support, or water supply. Chronic Constipation is associated with use of acetaminophen, aspirin and non-steroidal anti-inflammatory drugs. The explanation of these associations requires further investigation.

Giles R. Locke - One of the best experts on this subject based on the ideXlab platform.

  • cumulative incidence of Chronic Constipation a population based study 1988 2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.

  • Cumulative incidence of Chronic Constipation: a population-based study 1988–2003
    Alimentary Pharmacology & Therapeutics, 2007
    Co-Authors: R. S. Choung, Giles R. Locke, Cathy D. Schleck, Alan R. Zinsmeister, Nicholas J. Talley
    Abstract:

    Summary Aim  To estimate the cumulative incidence of Chronic Constipation and evaluate potential risk factors. Methods  In previous cross-sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of Chronic Constipation was defined as no reported Constipation or irritable bowel syndrome on their initial survey but reported Constipation on the second survey. Results  In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which Chronic Constipation could be defined. Over 12 years, the cumulative incidence of Chronic Constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of Chronic Constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of Chronic Constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset Chronic Constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion  The cumulative incidence of Chronic Constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.