The Experts below are selected from a list of 90 Experts worldwide ranked by ideXlab platform
Steven B Heymsfield - One of the best experts on this subject based on the ideXlab platform.
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Urinary 3-Methylhistidine Excretion: Association With Total Body Skeletal Muscle Mass by Computerized Axial Tomography
2016Co-Authors: Zimian Wang, Dagger Paul Deurenberg, Dagger Dwight E. Matthews, Steven B HeymsfieldAbstract:ABSTRACT. Background: The urinary excretion of endogenous 3-methylhistidine (3-MH) has been proposed as a predictor of skeletal muscle mass (SM). In this study, we report the relation-ship between 24-hour urinary 3-MH excretion and SM. Methods: Total body SM was measured by multiscan Computerized Axial Tomography (CT) in a sample of 10 healthy adult men who fol-lowed a meat-free diet for 7 days. 3-MH was measured during the last 3 days of the meat-free diet protocol on consecutive 24-hour urine collections. Results: The 3-MH excretion was 216.3 ± 44.7 μmol/d (mean ± SD) and was found well associated with SM (in kilograms), SM = 0.0887 × 3-MH + 11.8; r =.88, p <.001. Com-pared with CT, the previous 3-MH-SM prediction equation sug-gested by Lukaski et al underestimated SM by an average of 8.9 kg in the 10 healthy men. This difference was caused by the Burkinshaw-Cohn neutron activation model, which underesti
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urinary 3 methylhistidine excretion association with total body skeletal muscle mass by Computerized Axial Tomography
Journal of Parenteral and Enteral Nutrition, 1998Co-Authors: Zimian Wang, P Deurenberg, Dwight E Matthews, Steven B HeymsfieldAbstract:Background: The urinary excretion of endogenous 3-methylhistidine (3-MH) has been proposed as a predictor of skeletal muscle mass (SM). In this study, we report the relationship between 24-hour urinary 3-MH excretion and SM. Methods: Total body SM was measured by multiscan Computerized Axial Tomography (CT) in a sample of 10 healthy adult men who followed a meat-free diet for 7 days. 3-MH was measured during the last 3 days of the meat-free diet protocol on consecutive 24-hour urine collections. Results: The 3-MH excretion was 216.3 ± 44.7 μmol/d (mean ± SD) and was found well associated with SM (in kilograms), SM = 0.0887 × 3-MH + 11.8; r = .88, p < .001. Compared with CT, the previous 3-MH-SM prediction equation suggested by Lukaski et al underestimated SM by an average of 8.9 kg in the 10 healthy men. This difference was caused by the Burkinshaw-Cohn neutron activation model, which underestimated SM and was used as the reference in the Lukaski method. Conclusions: Twenty-four-hour urinary 3-MH excretio...
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total body skeletal muscle mass evaluation of 24 h urinary creatinine excretion by Computerized Axial Tomography
The American Journal of Clinical Nutrition, 1996Co-Authors: Z Wang, Dwight E Matthews, Dympna Gallagher, M E Nelson, Steven B HeymsfieldAbstract:A classic body-composition method is estimation of total-body skeletal muscle mass (SM, in kg) from 24-h urinary creatinine excretion (in g). Two approaches of unknown validity have been used to calculate SM from creatinine : one assumes a constant ratio of SM to creatinine, the so-called creatinine equivalence (k), and that SM = k X creatinine ; the other suggests a highly variable ratio of SM to creatinine and is based on regression equations of the form SM = b + a X creatinine. We explored these two extreme possibilities by measuring SM with whole-body Computerized Axial Tomography and collecting urinary creatinine during meat-free dietary conditions in 12 healthy adult men. Prediction equations were developed in the men that fit these two models : SM = 21.8 X creatinine (SD and CV of the ratio of SM to creatinine : 1.3 kg and 6.0%, respectively) and SM = 18.9 X creatinine + 4.1 (r = 0.92, P = 2.55 x 10 -5 , SEE = 1.89 kg). The validity of each model is reviewed in the context of theoretical aspects of creatine-creatinine metabolism. This first investigation of the method of measuring urinary creatinine excretion to determine SM by using modern techniques raises important practical and basic questions related to SM prediction.
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application of Computerized Axial Tomography in the study of body composition evaluation of lipid water protein and mineral in healthy men
Basic life sciences, 1993Co-Authors: Zimian Wang, Stanley Heshka, Steven B HeymsfieldAbstract:The molecular level of body composition is composed of lipid, water, protein, bone mineral (Mo), and soft tissue mineral (Ms). Although at present there are several in vivo methods at the molecular level, each method measures only one or two components. Moreover, most present methods measure only total body and not regional content of a components. The purpose of this investigation was to validate a new method based on multiple cross-sectional Computerized Axial Tomography (CT) images that allows simultaneous measurement of total and regional amounts of 5 molecular components.
Dwight E Matthews - One of the best experts on this subject based on the ideXlab platform.
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urinary 3 methylhistidine excretion association with total body skeletal muscle mass by Computerized Axial Tomography
Journal of Parenteral and Enteral Nutrition, 1998Co-Authors: Zimian Wang, P Deurenberg, Dwight E Matthews, Steven B HeymsfieldAbstract:Background: The urinary excretion of endogenous 3-methylhistidine (3-MH) has been proposed as a predictor of skeletal muscle mass (SM). In this study, we report the relationship between 24-hour urinary 3-MH excretion and SM. Methods: Total body SM was measured by multiscan Computerized Axial Tomography (CT) in a sample of 10 healthy adult men who followed a meat-free diet for 7 days. 3-MH was measured during the last 3 days of the meat-free diet protocol on consecutive 24-hour urine collections. Results: The 3-MH excretion was 216.3 ± 44.7 μmol/d (mean ± SD) and was found well associated with SM (in kilograms), SM = 0.0887 × 3-MH + 11.8; r = .88, p < .001. Compared with CT, the previous 3-MH-SM prediction equation suggested by Lukaski et al underestimated SM by an average of 8.9 kg in the 10 healthy men. This difference was caused by the Burkinshaw-Cohn neutron activation model, which underestimated SM and was used as the reference in the Lukaski method. Conclusions: Twenty-four-hour urinary 3-MH excretio...
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total body skeletal muscle mass evaluation of 24 h urinary creatinine excretion by Computerized Axial Tomography
The American Journal of Clinical Nutrition, 1996Co-Authors: Z Wang, Dwight E Matthews, Dympna Gallagher, M E Nelson, Steven B HeymsfieldAbstract:A classic body-composition method is estimation of total-body skeletal muscle mass (SM, in kg) from 24-h urinary creatinine excretion (in g). Two approaches of unknown validity have been used to calculate SM from creatinine : one assumes a constant ratio of SM to creatinine, the so-called creatinine equivalence (k), and that SM = k X creatinine ; the other suggests a highly variable ratio of SM to creatinine and is based on regression equations of the form SM = b + a X creatinine. We explored these two extreme possibilities by measuring SM with whole-body Computerized Axial Tomography and collecting urinary creatinine during meat-free dietary conditions in 12 healthy adult men. Prediction equations were developed in the men that fit these two models : SM = 21.8 X creatinine (SD and CV of the ratio of SM to creatinine : 1.3 kg and 6.0%, respectively) and SM = 18.9 X creatinine + 4.1 (r = 0.92, P = 2.55 x 10 -5 , SEE = 1.89 kg). The validity of each model is reviewed in the context of theoretical aspects of creatine-creatinine metabolism. This first investigation of the method of measuring urinary creatinine excretion to determine SM by using modern techniques raises important practical and basic questions related to SM prediction.
Zimian Wang - One of the best experts on this subject based on the ideXlab platform.
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Urinary 3-Methylhistidine Excretion: Association With Total Body Skeletal Muscle Mass by Computerized Axial Tomography
2016Co-Authors: Zimian Wang, Dagger Paul Deurenberg, Dagger Dwight E. Matthews, Steven B HeymsfieldAbstract:ABSTRACT. Background: The urinary excretion of endogenous 3-methylhistidine (3-MH) has been proposed as a predictor of skeletal muscle mass (SM). In this study, we report the relation-ship between 24-hour urinary 3-MH excretion and SM. Methods: Total body SM was measured by multiscan Computerized Axial Tomography (CT) in a sample of 10 healthy adult men who fol-lowed a meat-free diet for 7 days. 3-MH was measured during the last 3 days of the meat-free diet protocol on consecutive 24-hour urine collections. Results: The 3-MH excretion was 216.3 ± 44.7 μmol/d (mean ± SD) and was found well associated with SM (in kilograms), SM = 0.0887 × 3-MH + 11.8; r =.88, p <.001. Com-pared with CT, the previous 3-MH-SM prediction equation sug-gested by Lukaski et al underestimated SM by an average of 8.9 kg in the 10 healthy men. This difference was caused by the Burkinshaw-Cohn neutron activation model, which underesti
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urinary 3 methylhistidine excretion association with total body skeletal muscle mass by Computerized Axial Tomography
Journal of Parenteral and Enteral Nutrition, 1998Co-Authors: Zimian Wang, P Deurenberg, Dwight E Matthews, Steven B HeymsfieldAbstract:Background: The urinary excretion of endogenous 3-methylhistidine (3-MH) has been proposed as a predictor of skeletal muscle mass (SM). In this study, we report the relationship between 24-hour urinary 3-MH excretion and SM. Methods: Total body SM was measured by multiscan Computerized Axial Tomography (CT) in a sample of 10 healthy adult men who followed a meat-free diet for 7 days. 3-MH was measured during the last 3 days of the meat-free diet protocol on consecutive 24-hour urine collections. Results: The 3-MH excretion was 216.3 ± 44.7 μmol/d (mean ± SD) and was found well associated with SM (in kilograms), SM = 0.0887 × 3-MH + 11.8; r = .88, p < .001. Compared with CT, the previous 3-MH-SM prediction equation suggested by Lukaski et al underestimated SM by an average of 8.9 kg in the 10 healthy men. This difference was caused by the Burkinshaw-Cohn neutron activation model, which underestimated SM and was used as the reference in the Lukaski method. Conclusions: Twenty-four-hour urinary 3-MH excretio...
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application of Computerized Axial Tomography in the study of body composition evaluation of lipid water protein and mineral in healthy men
Basic life sciences, 1993Co-Authors: Zimian Wang, Stanley Heshka, Steven B HeymsfieldAbstract:The molecular level of body composition is composed of lipid, water, protein, bone mineral (Mo), and soft tissue mineral (Ms). Although at present there are several in vivo methods at the molecular level, each method measures only one or two components. Moreover, most present methods measure only total body and not regional content of a components. The purpose of this investigation was to validate a new method based on multiple cross-sectional Computerized Axial Tomography (CT) images that allows simultaneous measurement of total and regional amounts of 5 molecular components.
G R Harrison - One of the best experts on this subject based on the ideXlab platform.
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Topographical anatomy of the lumbar epidural region: an in vivo study using Computerized Axial Tomography.
BJA: British Journal of Anaesthesia, 1999Co-Authors: G R HarrisonAbstract:The lumbar epidural region was studied using Computerized Tomography. This technique allows examination of the region in vivo. It confirmed that the spinal canal is oval in the upper lumbar region, becoming triangular lower down, and that the ligamenta flava form a posterior recess to the vertebral canal. Epidural fat is confined to this region between the ligamenta flava and the intervertebral foramina, and the dura mater lies apposed to the walls of the vertebral canal except where there is epidural fat. The absence of a posterior midline fold of dura mater was noted, and discussed in the light of other studies.
Z Wang - One of the best experts on this subject based on the ideXlab platform.
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total body skeletal muscle mass evaluation of 24 h urinary creatinine excretion by Computerized Axial Tomography
The American Journal of Clinical Nutrition, 1996Co-Authors: Z Wang, Dwight E Matthews, Dympna Gallagher, M E Nelson, Steven B HeymsfieldAbstract:A classic body-composition method is estimation of total-body skeletal muscle mass (SM, in kg) from 24-h urinary creatinine excretion (in g). Two approaches of unknown validity have been used to calculate SM from creatinine : one assumes a constant ratio of SM to creatinine, the so-called creatinine equivalence (k), and that SM = k X creatinine ; the other suggests a highly variable ratio of SM to creatinine and is based on regression equations of the form SM = b + a X creatinine. We explored these two extreme possibilities by measuring SM with whole-body Computerized Axial Tomography and collecting urinary creatinine during meat-free dietary conditions in 12 healthy adult men. Prediction equations were developed in the men that fit these two models : SM = 21.8 X creatinine (SD and CV of the ratio of SM to creatinine : 1.3 kg and 6.0%, respectively) and SM = 18.9 X creatinine + 4.1 (r = 0.92, P = 2.55 x 10 -5 , SEE = 1.89 kg). The validity of each model is reviewed in the context of theoretical aspects of creatine-creatinine metabolism. This first investigation of the method of measuring urinary creatinine excretion to determine SM by using modern techniques raises important practical and basic questions related to SM prediction.