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Maria De Fatima Guerreiro Godoy - One of the best experts on this subject based on the ideXlab platform.
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primary Congenital Lymphedema in the upper limbs of children case series
International Journal of Pediatrics, 2019Co-Authors: Maria De Fatima Guerreiro Godoy, Ana Carolina Pereira De Godoy, Jose Maria Pereira De GodoyAbstract:The aim of the present study was to report a case series involving the treatment of primary Congenital Lymphedema using the Godoy method. Eight children (seven girls and one boy) with primary Congenital Lymphedema of the upper limbs treated at the Godoy Clinic. A retrospective clinical trial was conducted to evaluate treatment for primary Congenital Lymphedema of the upper limbs in children using the Godoy & Godoy lymphatic therapy method. The first treatment option for all children was cervical lymphatic therapy. The mothers were trained in the technique under the supervision of the team and, after demonstrating the ability to perform the therapy, were then free to continue cervical stimulation on their children at home. A reduction in edema was found in all children throughout treatment, ranging from two months to two years.
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Cervical Stimulation in the Treatment of Children with Lymphedema of All Four Extremities: A Case Report and Literature Review.
Case reports in pediatrics, 2017Co-Authors: Lívia Maria Pereira De Godoy, Jose Maria Pereira De Godoy, Paula Pereira De Godoy Capeletto, Maria De Fatima Guerreiro GodoyAbstract:Aim. The aim of this study is to report on the use of cervical stimulation as monotherapy to reduce swelling and normalize the size of limbs in two children with Lymphedema of all four extremities. Case Presentation. One child also had hemifacial edema. In both cases, the mothers were trained to perform cervical stimulation under professional supervision. The cases of two girls, one of eight months and the other of six months, with primary Congenital Lymphedema are described. Outcome. After clinical diagnosis, the patients started treatment with cervical stimulation three times per week. The mothers were trained in cervical stimulation and, when the therapy team was confident about the mothers’ ability to perform the technique, the children began to be treated at home. The Godoy & Godoy cervical stimulation technique consists of around 20 to 30 light stroking movements per minute in the cervical region which stimulate the lymphatics. Perimetric measurements were made of the feet, legs, and the hands. Only two points (3 and 6 cm) along the dorsum of the feet and hands and points at 5 cm intervals up the legs starting at the ankle were considered. Today, the children are 5 and 6 years of age, without edema and with a normal life, without limitations, except with respect to precautions against injuries to the limbs and against infections particularly erysipelas. Conclusion. Cervical Lymphatic Therapy as monotherapy is an option in the treatment of primary Congenital Lymphedema.
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adaptations in the treatment of Congenital Lymphedema centered on the quality of life
Case Reports in Medicine, 2014Co-Authors: Jose Maria Pereira De Godoy, Ana Paula Sanchez, Daniel Zucchi Libanore, Maria De Fatima Guerreiro GodoyAbstract:Case Description. This report describes the evolution, necessary adaptations, and complications in the treatment of a 9-year-old child with primary Congenital Lymphedema. Description of Intervention. The clinical treatment of Lymphedema was started in the first year of the patient’s life and for five years she was only treated using the Godoy & Godoy technique of cervical stimulation. Three years ago the patient was prescribed a compression stocking made from a cotton-polyester fabric (grosgrain) because of a sudden increase in the Lymphedema after she started to take growth hormones. Outcome and Conclusion. The combination of cervical stimulation and a compression stocking was effective to keep the child’s life relatively normal, performing all day-to-day and recreational activities.
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the godoy godoy cervical stimulation technique in the treatment of primary Congenital Lymphedema
Pediatric Reports, 2012Co-Authors: Jose Maria Pereira De Godoy, Ana Carolina Pereira De Godoy, Tânia Dias Guimaraes, Maria De Fatima Guerreiro GodoyAbstract:The aim of the current study is to report on the treatment of primary Lymphedema using a new form of therapy: cervical stimulation. In a prospective cohort study, 9 boys and 5 girls with primary Congenital Lymphedema were evaluated over two years. Age ranged from two months to 8.5 years. After diagnosis, all mothers were trained in the new technique. The Godoy & Godoy cervical stimulation technique consists of between 20 to 30 stimuli per minute using light movements in the cervical region. All the children were submitted to perimetric evaluations of the feet and legs; however, in this study only two points, 3 and 6 cm from the base of the big toe nail, were used. The two-tailed t-test was used for statistical analysis with an alpha error of 5% (P<0.05) considered acceptable. The size of the Lymphedematous feet was reduced and even normalized (P<0.0001) for all treated children. Cervical stimulation is a new option in the treatment of primary Congenital Lymphedema; its association with compression stockings has a synergistic effect in reducing the volume of Lymphedema.
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The godoy & godoy cervical stimulation technique in the treatment of primary Congenital Lymphedema.
Pediatric Reports, 2012Co-Authors: Jose Maria Pereira De Godoy, Ana Carolina Pereira De Godoy, Tânia Dias Guimaraes, Maria De Fatima Guerreiro GodoyAbstract:The aim of the current study is to report on the treatment of primary Lymphedema using a new form of therapy: cervical stimulation. In a prospective cohort study, 9 boys and 5 girls with primary Congenital Lymphedema were evaluated over two years. Age ranged from two months to 8.5 years. After diagnosis, all mothers were trained in the new technique. The Godoy & Godoy cervical stimulation technique consists of between 20 to 30 stimuli per minute using light movements in the cervical region. All the children were submitted to perimetric evaluations of the feet and legs; however, in this study only two points, 3 and 6 cm from the base of the big toe nail, were used. The two-tailed t-test was used for statistical analysis with an alpha error of 5% (P
Jose Maria Pereira De Godoy - One of the best experts on this subject based on the ideXlab platform.
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primary Congenital Lymphedema in the upper limbs of children case series
International Journal of Pediatrics, 2019Co-Authors: Maria De Fatima Guerreiro Godoy, Ana Carolina Pereira De Godoy, Jose Maria Pereira De GodoyAbstract:The aim of the present study was to report a case series involving the treatment of primary Congenital Lymphedema using the Godoy method. Eight children (seven girls and one boy) with primary Congenital Lymphedema of the upper limbs treated at the Godoy Clinic. A retrospective clinical trial was conducted to evaluate treatment for primary Congenital Lymphedema of the upper limbs in children using the Godoy & Godoy lymphatic therapy method. The first treatment option for all children was cervical lymphatic therapy. The mothers were trained in the technique under the supervision of the team and, after demonstrating the ability to perform the therapy, were then free to continue cervical stimulation on their children at home. A reduction in edema was found in all children throughout treatment, ranging from two months to two years.
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Cervical Stimulation in the Treatment of Children with Lymphedema of All Four Extremities: A Case Report and Literature Review.
Case reports in pediatrics, 2017Co-Authors: Lívia Maria Pereira De Godoy, Jose Maria Pereira De Godoy, Paula Pereira De Godoy Capeletto, Maria De Fatima Guerreiro GodoyAbstract:Aim. The aim of this study is to report on the use of cervical stimulation as monotherapy to reduce swelling and normalize the size of limbs in two children with Lymphedema of all four extremities. Case Presentation. One child also had hemifacial edema. In both cases, the mothers were trained to perform cervical stimulation under professional supervision. The cases of two girls, one of eight months and the other of six months, with primary Congenital Lymphedema are described. Outcome. After clinical diagnosis, the patients started treatment with cervical stimulation three times per week. The mothers were trained in cervical stimulation and, when the therapy team was confident about the mothers’ ability to perform the technique, the children began to be treated at home. The Godoy & Godoy cervical stimulation technique consists of around 20 to 30 light stroking movements per minute in the cervical region which stimulate the lymphatics. Perimetric measurements were made of the feet, legs, and the hands. Only two points (3 and 6 cm) along the dorsum of the feet and hands and points at 5 cm intervals up the legs starting at the ankle were considered. Today, the children are 5 and 6 years of age, without edema and with a normal life, without limitations, except with respect to precautions against injuries to the limbs and against infections particularly erysipelas. Conclusion. Cervical Lymphatic Therapy as monotherapy is an option in the treatment of primary Congenital Lymphedema.
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adaptations in the treatment of Congenital Lymphedema centered on the quality of life
Case Reports in Medicine, 2014Co-Authors: Jose Maria Pereira De Godoy, Ana Paula Sanchez, Daniel Zucchi Libanore, Maria De Fatima Guerreiro GodoyAbstract:Case Description. This report describes the evolution, necessary adaptations, and complications in the treatment of a 9-year-old child with primary Congenital Lymphedema. Description of Intervention. The clinical treatment of Lymphedema was started in the first year of the patient’s life and for five years she was only treated using the Godoy & Godoy technique of cervical stimulation. Three years ago the patient was prescribed a compression stocking made from a cotton-polyester fabric (grosgrain) because of a sudden increase in the Lymphedema after she started to take growth hormones. Outcome and Conclusion. The combination of cervical stimulation and a compression stocking was effective to keep the child’s life relatively normal, performing all day-to-day and recreational activities.
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the godoy godoy cervical stimulation technique in the treatment of primary Congenital Lymphedema
Pediatric Reports, 2012Co-Authors: Jose Maria Pereira De Godoy, Ana Carolina Pereira De Godoy, Tânia Dias Guimaraes, Maria De Fatima Guerreiro GodoyAbstract:The aim of the current study is to report on the treatment of primary Lymphedema using a new form of therapy: cervical stimulation. In a prospective cohort study, 9 boys and 5 girls with primary Congenital Lymphedema were evaluated over two years. Age ranged from two months to 8.5 years. After diagnosis, all mothers were trained in the new technique. The Godoy & Godoy cervical stimulation technique consists of between 20 to 30 stimuli per minute using light movements in the cervical region. All the children were submitted to perimetric evaluations of the feet and legs; however, in this study only two points, 3 and 6 cm from the base of the big toe nail, were used. The two-tailed t-test was used for statistical analysis with an alpha error of 5% (P<0.05) considered acceptable. The size of the Lymphedematous feet was reduced and even normalized (P<0.0001) for all treated children. Cervical stimulation is a new option in the treatment of primary Congenital Lymphedema; its association with compression stockings has a synergistic effect in reducing the volume of Lymphedema.
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The godoy & godoy cervical stimulation technique in the treatment of primary Congenital Lymphedema.
Pediatric Reports, 2012Co-Authors: Jose Maria Pereira De Godoy, Ana Carolina Pereira De Godoy, Tânia Dias Guimaraes, Maria De Fatima Guerreiro GodoyAbstract:The aim of the current study is to report on the treatment of primary Lymphedema using a new form of therapy: cervical stimulation. In a prospective cohort study, 9 boys and 5 girls with primary Congenital Lymphedema were evaluated over two years. Age ranged from two months to 8.5 years. After diagnosis, all mothers were trained in the new technique. The Godoy & Godoy cervical stimulation technique consists of between 20 to 30 stimuli per minute using light movements in the cervical region. All the children were submitted to perimetric evaluations of the feet and legs; however, in this study only two points, 3 and 6 cm from the base of the big toe nail, were used. The two-tailed t-test was used for statistical analysis with an alpha error of 5% (P
Giovanni Serra - One of the best experts on this subject based on the ideXlab platform.
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Aplasia cutis congenita, skull defect, brain heterotopia, and intestinal lymphangiectasia.
American journal of medical genetics. Part A, 2005Co-Authors: Eugenio Bonioli, Raoul C Hennekam, Gianantonio Spena, Guido Morcaldi, Antonio Di Stefano, Giovanni Serra, Carlo BelliniAbstract:We describe a female infant with a previously unreported combination of manifestations characterized by aplasia cutis, skull defect, brain heterotopia, mild Congenital Lymphedema, and intestinal lymphangiectasia. The association of intestinal lymphangiectasia and aplasia cutis, and the association of intestinal lymphangiectasia with brain heterotopia in the Lymphedema-lymphangiectasia-mental retardation syndrome have been described in single reports. In one family, the association of cortical dysplasia and Congenital Lymphedema have been related to mutations in the RELN gene.
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Aplasia cutis congenita, skull defect, brain heterotopia, and intestinal lymphangiectasia.
American Journal of Medical Genetics Part A, 2005Co-Authors: Eugenio Bonioli, Raoul C Hennekam, Gianantonio Spena, Guido Morcaldi, Antonio Di Stefano, Giovanni Serra, Carlo BelliniAbstract:We describe a female infant with a previously unreported combination of manifestations characterized by aplasia cutis, skull defect, brain heterotopia, mild Congenital Lymphedema, and intestinal lymphangiectasia. The association of intestinal lymphangiectasia and aplasia cutis, and the association of intestinal lymphangiectasia with brain heterotopia in the Lymphedema-lymphangiectasia-mental retardation syndrome have been described in single reports. In one family, the association of cortical dysplasia and Congenital Lymphedema have been related to mutations in the RELN gene. (C) 2004 Wiley-Liss, Inc.
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hennekam syndrome presenting as nonimmune hydrops fetalis Congenital chylothorax and Congenital pulmonary lymphangiectasia
American Journal of Medical Genetics Part A, 2003Co-Authors: Carlo Bellini, Francesco Boccardo, C Campisi, Raoul C Hennekam, Massimo Mazzella, Cesare Arioni, Gioconda Taddei, Paolo Tomà, Giovanni SerraAbstract:We report a female infant with Congenital Lymphedema, facial anomalies, intestinal lymphangiectasia consistent with a diagnosis of Hennekam syndrome. At birth the patient presented with severe respiratory distress due to nonimmune hydrops fetalis, a Congenital chylothorax (CC), and pulmonary lymphangiectasia. Hydrops fetalis may be present in newborns with the Hennekam syndrome. Lymphoscintigraphy can be useful in explaining pleural-pulmonary involvement of this generalized lymph vessel malformation syndrome. (C) 2003 Wiley-Liss, Inc
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Hennekam syndrome presenting as nonimmune hydrops fetalis, Congenital chylothorax, and Congenital pulmonary lymphangiectasia.
American journal of medical genetics. Part A, 2003Co-Authors: Carlo Bellini, Francesco Boccardo, Massimo Mazzella, Cesare Arioni, Corradino Campisi, Gioconda Taddei, Paolo Tomà, Raoul C Hennekam, Giovanni SerraAbstract:We report a female infant with Congenital Lymphedema, facial anomalies, intestinal lymphangiectasia consistent with a diagnosis of Hennekam syndrome. At birth the patient presented with severe respiratory distress due to nonimmune hydrops fetalis, a Congenital chylothorax (CC), and pulmonary lymphangiectasia. Hydrops fetalis may be present in newborns with the Hennekam syndrome. Lymphoscintigraphy can be useful in explaining pleural-pulmonary involvement of this generalized lymph vessel malformation syndrome.
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lymphoscintigraphic evaluation of Congenital Lymphedema of the newborn
Clinical Nuclear Medicine, 2002Co-Authors: Carlo Bellini, Francesco Boccardo, C Campisi, Massimo Mazzella, Cesare Arioni, G Taddei, Giovanni SerraAbstract:The authors present a case of the Hennekam syndrome diagnosed in a newborn. Lymphedema is usually present in this syndrome, and the lymphoscintigraphic imaging findings for its detection are discussed. This case confirms the utility of lymphoscintigraphy in providing important physiologic and anatomic information for presurgical planning. An etiologic diagnosis could possibly be obtained. The procedure is relatively easy to perform, safe, reliable, minimally invasive, and not uncomfortable for the patient. It should be considered a valuable diagnostic tool, especially in newborns, in whom conventional contrast lymphoangiography is difficult to perform.
Carlo Bellini - One of the best experts on this subject based on the ideXlab platform.
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Aplasia cutis congenita, skull defect, brain heterotopia, and intestinal lymphangiectasia.
American journal of medical genetics. Part A, 2005Co-Authors: Eugenio Bonioli, Raoul C Hennekam, Gianantonio Spena, Guido Morcaldi, Antonio Di Stefano, Giovanni Serra, Carlo BelliniAbstract:We describe a female infant with a previously unreported combination of manifestations characterized by aplasia cutis, skull defect, brain heterotopia, mild Congenital Lymphedema, and intestinal lymphangiectasia. The association of intestinal lymphangiectasia and aplasia cutis, and the association of intestinal lymphangiectasia with brain heterotopia in the Lymphedema-lymphangiectasia-mental retardation syndrome have been described in single reports. In one family, the association of cortical dysplasia and Congenital Lymphedema have been related to mutations in the RELN gene.
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Aplasia cutis congenita, skull defect, brain heterotopia, and intestinal lymphangiectasia.
American Journal of Medical Genetics Part A, 2005Co-Authors: Eugenio Bonioli, Raoul C Hennekam, Gianantonio Spena, Guido Morcaldi, Antonio Di Stefano, Giovanni Serra, Carlo BelliniAbstract:We describe a female infant with a previously unreported combination of manifestations characterized by aplasia cutis, skull defect, brain heterotopia, mild Congenital Lymphedema, and intestinal lymphangiectasia. The association of intestinal lymphangiectasia and aplasia cutis, and the association of intestinal lymphangiectasia with brain heterotopia in the Lymphedema-lymphangiectasia-mental retardation syndrome have been described in single reports. In one family, the association of cortical dysplasia and Congenital Lymphedema have been related to mutations in the RELN gene. (C) 2004 Wiley-Liss, Inc.
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hennekam syndrome presenting as nonimmune hydrops fetalis Congenital chylothorax and Congenital pulmonary lymphangiectasia
American Journal of Medical Genetics Part A, 2003Co-Authors: Carlo Bellini, Francesco Boccardo, C Campisi, Raoul C Hennekam, Massimo Mazzella, Cesare Arioni, Gioconda Taddei, Paolo Tomà, Giovanni SerraAbstract:We report a female infant with Congenital Lymphedema, facial anomalies, intestinal lymphangiectasia consistent with a diagnosis of Hennekam syndrome. At birth the patient presented with severe respiratory distress due to nonimmune hydrops fetalis, a Congenital chylothorax (CC), and pulmonary lymphangiectasia. Hydrops fetalis may be present in newborns with the Hennekam syndrome. Lymphoscintigraphy can be useful in explaining pleural-pulmonary involvement of this generalized lymph vessel malformation syndrome. (C) 2003 Wiley-Liss, Inc
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Hennekam syndrome presenting as nonimmune hydrops fetalis, Congenital chylothorax, and Congenital pulmonary lymphangiectasia.
American journal of medical genetics. Part A, 2003Co-Authors: Carlo Bellini, Francesco Boccardo, Massimo Mazzella, Cesare Arioni, Corradino Campisi, Gioconda Taddei, Paolo Tomà, Raoul C Hennekam, Giovanni SerraAbstract:We report a female infant with Congenital Lymphedema, facial anomalies, intestinal lymphangiectasia consistent with a diagnosis of Hennekam syndrome. At birth the patient presented with severe respiratory distress due to nonimmune hydrops fetalis, a Congenital chylothorax (CC), and pulmonary lymphangiectasia. Hydrops fetalis may be present in newborns with the Hennekam syndrome. Lymphoscintigraphy can be useful in explaining pleural-pulmonary involvement of this generalized lymph vessel malformation syndrome.
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lymphoscintigraphic evaluation of Congenital Lymphedema of the newborn
Clinical Nuclear Medicine, 2002Co-Authors: Carlo Bellini, Francesco Boccardo, C Campisi, Massimo Mazzella, Cesare Arioni, G Taddei, Giovanni SerraAbstract:The authors present a case of the Hennekam syndrome diagnosed in a newborn. Lymphedema is usually present in this syndrome, and the lymphoscintigraphic imaging findings for its detection are discussed. This case confirms the utility of lymphoscintigraphy in providing important physiologic and anatomic information for presurgical planning. An etiologic diagnosis could possibly be obtained. The procedure is relatively easy to perform, safe, reliable, minimally invasive, and not uncomfortable for the patient. It should be considered a valuable diagnostic tool, especially in newborns, in whom conventional contrast lymphoangiography is difficult to perform.
Julia Hoefele - One of the best experts on this subject based on the ideXlab platform.
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Congenital Lymphedema as a rare and first symptom of tuberous sclerosis complex
Gene, 2020Co-Authors: Jurgen Klinner, Marcus Kruger, Theresa Brunet, Christine Makowski, Korbinian M Riedhammer, Andreas Mollweide, Matias Wagner, Julia HoefeleAbstract:Abstract Lymphedema are characterized by interstitial edema leading to swelling of extremities. They can be divided into primary and secondary Lymphedema. Developmental abnormalities of the lymphatic system are responsible for the primary form of Lymphedema. The secondary form of Lymphedema is caused by damage of the lymphatic system due to external factors. Lymphedema can rarely be observed in patients with tuberous sclerosis complex (TSC), which is a neurocutaneous syndrome caused by pathogenic variants in the genes TSC1 or TSC2. Patients with TSC usually present with neurological manifestations and the development of multiple benign tumors of ectodermal origin. Typical onset for several symptoms is during the first year of life and in some cases lesions can be detected prenatally. Epilepsy is one of the most common manifestations, affecting up to 90% of TSC patients, and is associated with developmental delay. Early pharmacotherapy improves long term patient outcome. Trio exome sequencing was performed in a 3 weeks old girl with Congenital Lymphedema of the right lower extremity. Using a filter for de novo variants, the heterozygous missense variant c.2524C>T, p.(Gln842Ter) in TSC1 (NM_000368.4) could be identified. After the first onset of infantile spams at age 7 months treatment with vigabatrin was started immediately. We propose to include TSC1 and TSC2 analysis in the diagnostic work-up of patients with (isolated) Congenital Lymphedema as early diagnosis facilitates consequent treatment strategies potentially improving the prognosis of TSC patients.