The Experts below are selected from a list of 1245 Experts worldwide ranked by ideXlab platform
Sunil S. Jalalpure - One of the best experts on this subject based on the ideXlab platform.
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Effect of Curcuma zedoaria Rosc root extracts on behavioral and radiology changes in arthritic rats.
Journal of advanced pharmaceutical technology & research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study was conducted to evaluate the effects of petroleum ether, chloroform, and methanol root extracts of Curcuma zedoaria Rosc (Family: Zingiberaceae) on behavioral and radiology aspects of Freund's Complete Adjuvant (FCA)-induced monoarthritis in left ankle joint of rats using open-field test. Traditionally, Curcuma zedoaria root has been used as anti-inflammatory and antiarthritic drug. Behavioral aspects include latency time to explore, ambulatory, rearing, grooming, urination, and defecation. Animals were divided into ten groups each of six rats, all the animals were subjected to open-field test before the induction of arthritis at 0 day and thereafter 3, 7, 14 21, 28, 35, and 42 days of postinoculation FCA injection. The rat was placed in an open field and observed all behavioral aspects for 5 minutes and radiography analysis was made on day 42. Selected doses were 10 mg/kg.i.p. Indomethacin 200 mg/kg.p.o. marketed herbal drug Rumalaya forte and 200 and 400 mg/kg.p.o. of each extracts, respectively. The results showed significant decrease in ambulation and rearing; however, increase in latency time to explore and grooming, urination, and defecation in control group, but in contrast, drug-treated groups showed significant recovery in all behavioral aspects except methanol groups. On the basis of radiography examination, control and methanol groups showed highest swelling compared with normal group; however, all drug-treated groups showed significant reduced swelling. Treatments with petroleum ether and chloroform extracts recovery were observed in behavioral and radiological aspects in arthritic rats.
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Evaluation of Anti-Inflammatory Effect of Ethanolic And Aqueous extracts of Curcuma zedoaria Rosc Root
International Journal of Drug Development and Research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study investigates the antiinflammatory activity of ethanolic and aqueous extracts of Curcuma zedoaria Rosc roots in albino rats by using Carrageenan and Histamine induced hind paw edema method. The medicinal values of Curcuma zedoaria root have been mentioned in ancient literature as useful in disorders of inflammation. Dried pulverized root of Curcuma zedoaria was extracted with ethanol by using soxhlet apparatus and aqueous extract was prepared by cold maceration. The paw edema was induced by subplantar injection of above inflammagens and oedema volume was recorded using a Plethysmometer. Ethanol 200 and 400 mg/kg root extracts showed significant p
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evaluation of anti inflammatory effect of ethanolic and aqueous extracts of Curcuma zedoaria rosc root
International Journal of Drug Development and Research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study investigates the antiinflammatory activity of ethanolic and aqueous extracts of Curcuma zedoaria Rosc roots in albino rats by using Carrageenan and Histamine induced hind paw edema method. The medicinal values of Curcuma zedoaria root have been mentioned in ancient literature as useful in disorders of inflammation. Dried pulverized root of Curcuma zedoaria was extracted with ethanol by using soxhlet apparatus and aqueous extract was prepared by cold maceration. The paw edema was induced by subplantar injection of above inflammagens and oedema volume was recorded using a Plethysmometer. Ethanol 200 and 400 mg/kg root extracts showed significant p<0.001 anti-inflammatory activity on 2nd to 6th hours and aqueous root extract showed non-significant antiinflammatory activity when compared with control group using standard groups (Indomethacin 10 mg/kg.i.p and Rumalaya forte 200 mg/kg p.o). It concludes that ethanolic root extract of Curcuma zedoaria Rosc augments that it shows good antiinflammatory activity against carrageenan and histamine induced paw edema in rats.
Yonara Anandari - One of the best experts on this subject based on the ideXlab platform.
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The Effect of Extraction Condition on The Polyphenol Content and Antioxidant Activity of Curcuma zedoaria (Christm.) Roscoe Rhizome
Indonesian Journal of Pharmaceutical Science and Technology, 2017Co-Authors: Lia Marliani, Wempi Budiana, Yonara AnandariAbstract:White turmeric ( Curcuma zedoaria (Christm.) Roscoe) is one of Indonesian herbal medicine. The extraction process to get active compound was influenced by some factor such as solvent, temperature, time, and method of extraction. The objective of this study was to determine the significant factor of extraction that is solvent, temperature and time of extraction on the polyphenol content and antioxidant activity of white turmeric ( Curcuma zedoaria (Christm.) Roscoe) rhizome. Extraction was done by dynamic maceration method with variations (23 factor variable design) of solvent (ethanol 95% and water), temperature (25°C and 70°C), time (6 and 24 hours). The method of analysis of polyphenol content using Folin Ciocalteu reagent, and the antioxidant activity using DPPH free radical reduction method. The experiment design and data analysis using software Design Expert ver.10. The result showed that extraction using ethanol 95% at 70°C for 24 hours was gave high polyphenol content and antioxidant activity. Data analysis was showed that polyphenol content and antioxidant activity was influenced only by solvent of extraction. This study indicated that solvent is significant extraction factor for polyphenol content and antioxidant activity of white turmeric ( Curcuma zedoaria (Christm.) Roscoe) rhizome. Keywords: Antioxidant, Curcuma zedoaria (Christm.) Roscoe, extraction, polyphenol
Luiz Fernando Rolim De Almeida - One of the best experts on this subject based on the ideXlab platform.
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Kinetin establish the volatile chemical profile after rhizome dormancy is released in Curcuma zedoaria (Christm.) Roscoe.
Natural product research, 2020Co-Authors: Roberto De Oliveira Portella, Marcia Ortiz Mayo Marques, Elizabeth Orika Ono, Paulo Sérgio Siberti Da Silva, Adalton Mazetti Fernandes, Luiz Fernando Rolim De AlmeidaAbstract:AbstractThe aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizom...
Madan L. Kaushik - One of the best experts on this subject based on the ideXlab platform.
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Effect of Curcuma zedoaria Rosc root extracts on behavioral and radiology changes in arthritic rats.
Journal of advanced pharmaceutical technology & research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study was conducted to evaluate the effects of petroleum ether, chloroform, and methanol root extracts of Curcuma zedoaria Rosc (Family: Zingiberaceae) on behavioral and radiology aspects of Freund's Complete Adjuvant (FCA)-induced monoarthritis in left ankle joint of rats using open-field test. Traditionally, Curcuma zedoaria root has been used as anti-inflammatory and antiarthritic drug. Behavioral aspects include latency time to explore, ambulatory, rearing, grooming, urination, and defecation. Animals were divided into ten groups each of six rats, all the animals were subjected to open-field test before the induction of arthritis at 0 day and thereafter 3, 7, 14 21, 28, 35, and 42 days of postinoculation FCA injection. The rat was placed in an open field and observed all behavioral aspects for 5 minutes and radiography analysis was made on day 42. Selected doses were 10 mg/kg.i.p. Indomethacin 200 mg/kg.p.o. marketed herbal drug Rumalaya forte and 200 and 400 mg/kg.p.o. of each extracts, respectively. The results showed significant decrease in ambulation and rearing; however, increase in latency time to explore and grooming, urination, and defecation in control group, but in contrast, drug-treated groups showed significant recovery in all behavioral aspects except methanol groups. On the basis of radiography examination, control and methanol groups showed highest swelling compared with normal group; however, all drug-treated groups showed significant reduced swelling. Treatments with petroleum ether and chloroform extracts recovery were observed in behavioral and radiological aspects in arthritic rats.
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Evaluation of Anti-Inflammatory Effect of Ethanolic And Aqueous extracts of Curcuma zedoaria Rosc Root
International Journal of Drug Development and Research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study investigates the antiinflammatory activity of ethanolic and aqueous extracts of Curcuma zedoaria Rosc roots in albino rats by using Carrageenan and Histamine induced hind paw edema method. The medicinal values of Curcuma zedoaria root have been mentioned in ancient literature as useful in disorders of inflammation. Dried pulverized root of Curcuma zedoaria was extracted with ethanol by using soxhlet apparatus and aqueous extract was prepared by cold maceration. The paw edema was induced by subplantar injection of above inflammagens and oedema volume was recorded using a Plethysmometer. Ethanol 200 and 400 mg/kg root extracts showed significant p
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evaluation of anti inflammatory effect of ethanolic and aqueous extracts of Curcuma zedoaria rosc root
International Journal of Drug Development and Research, 2011Co-Authors: Madan L. Kaushik, Sunil S. JalalpureAbstract:The present study investigates the antiinflammatory activity of ethanolic and aqueous extracts of Curcuma zedoaria Rosc roots in albino rats by using Carrageenan and Histamine induced hind paw edema method. The medicinal values of Curcuma zedoaria root have been mentioned in ancient literature as useful in disorders of inflammation. Dried pulverized root of Curcuma zedoaria was extracted with ethanol by using soxhlet apparatus and aqueous extract was prepared by cold maceration. The paw edema was induced by subplantar injection of above inflammagens and oedema volume was recorded using a Plethysmometer. Ethanol 200 and 400 mg/kg root extracts showed significant p<0.001 anti-inflammatory activity on 2nd to 6th hours and aqueous root extract showed non-significant antiinflammatory activity when compared with control group using standard groups (Indomethacin 10 mg/kg.i.p and Rumalaya forte 200 mg/kg p.o). It concludes that ethanolic root extract of Curcuma zedoaria Rosc augments that it shows good antiinflammatory activity against carrageenan and histamine induced paw edema in rats.
Nosheen Asghar - One of the best experts on this subject based on the ideXlab platform.
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Phytopreventive antihypercholesterolmic and antilipidemic perspectives of zedoary (Curcuma zedoaria Roscoe.) herbal tea.
Lipids in health and disease, 2016Co-Authors: Sara Tariq, Muhammad Imran, Zarina Mushtaq, Nosheen AsgharAbstract:Background Metabolic syndrome is an increasingly prevalent problem, not only in industrialized developed countries, but in developing countries as well. The modern healthcare to reduce the dysfunction of metabolic syndrome is burdened with great problems of unsafe medicines and certain degree of side effects. Medicinal plants and derived component products are becoming increasingly popular in modern society as natural alternatives to synthetic multiple drugs for the treatment of hypercholesterolemia and hypertriglyceridemia. The present research work was carried out to evaluate the zedoary (Curcuma zedoaria Roscoe.) herbal tea (ZHT) for antihypercholestrolemic and antilipidemic perspectives in discerning consumers.
