The Experts below are selected from a list of 96 Experts worldwide ranked by ideXlab platform
E M Gaydou - One of the best experts on this subject based on the ideXlab platform.
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modifications of hepatic drug metabolizing enzyme activities in rats fed baobab seed oil containing Cyclopropenoid Fatty Acids
Food and Chemical Toxicology, 1995Co-Authors: A A Andrianaivorafehivola, Mariehelene Siess, E M GaydouAbstract:Abstract The effects on drug metabolizing enzymes of Cyclopropenoid Fatty Acids present in baobab seed oil were evaluated in rats fed either a diet with baobab seed oil (1.27% Cyclopropenoid Fatty Acids in the diet) or a diet with heated baobab seed oil (0.046% Cyclopropenoid Fatty Acids in the diet). Comparison was made with rats fed a mixture of oils that contained no Cyclopropenoid Fatty acid. Rats fed baobab oil showed retarded growth. In comparison with the other groups, the relative liver weights were markedly increased whereas cytochrome P -450 content and NADPH cytochrome c reductase and NADH cytochrome c reductase activities were decreased. In rats fed the heated baobab oil the relative liver weight was decreased and the cytochrome P -450 level and reductase activities were increased relative to levels in rats fed the unheated oil. Ethoxycoumarin deethylase, ethoxyresorufin deethylase and pentoxyresorufin depentylase activities, expressed on the basis of cytochrome P -450, were greater in the group fed unheated baobab seed oil. Cytosolic glutathione transferase activity was markedly decreased in rats fed fresh baobab seed oil and heating the oil, which reduced the content of Cyclopropenoid Fatty Acids, led to a considerable increase of this activity. UDP-glucuronyl transferase activities were not modified by the type of oil included in the diet. It is possible that the mechanisms of action of Cyclopropenoid Fatty Acids are related to alterations of membrane lipid composition or microsomal proteins.
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Determination of Cyclopropenoid Fatty Acids inSterculia seed oils from senegal
Journal of the American Oil Chemists’ Society, 1993Co-Authors: J. Miralles, E. Bassene, E M GaydouAbstract:Seed oils of Sterculia tomentosa and S. tragacantha (Sterculiaceae) were found to contain malvalic (5.8 and 5.1%), sterculic (11.3 and 30.2%) and dihydrosterculic (0.9 and 0.5%) Acids. The total amount of these two Cyclopropenoid Fatty Acids was established by^1H nuclear magnetic resonance and their cooccurrence by gas chromatography. Besides these unusual compounds, the main common Fatty Acids were palmitic (20 and 24%), oleic (21 and 15%) and linoleic (30 and 16%) Acids.
Jean Bezard - One of the best experts on this subject based on the ideXlab platform.
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effects of Cyclopropenoid Fatty Acids baobab seed oil on the Fatty acid profile of lipids from different tissues in the rat
Journal of Food Lipids, 1996Co-Authors: Joseph Gresti, Jean Paul Blond, Jean BezardAbstract:Rats were fed for 8 weeks a diet containing either Baobab seed oil (FBO) rich in Cyclopropenoid Fatty Acids (CPFA) or heated oil (HBO) devoid of CPFA. In FBO rats, compared to controls (CO), the monounsaturated Fatty acid content of adipose tissue lipids, liver triacylglycerols, liver and adrenal cholesteryl esters and liver, kidney, adrenal phospholipids were highly decreased to the benefit of saturated Fatty acid content. In cholesteryl esters and phospholipids, the arachidonic acid (20:4 n-6) content was markedly decreased, especially in adrenals. In adrenal cholesteryl esters, adrenic acid (22:4 n-6) content was decreased more than its precursor. The effects of HBO on the tissue lipid Fatty acid profile were practically absent. It is concluded that inhibition of Fatty acid desaturation by CPFA previously demonstrated in vitro, was reflected in vivo in tissue lipid Fatty acid composition.
A A Andrianaivorafehivola - One of the best experts on this subject based on the ideXlab platform.
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modifications of hepatic drug metabolizing enzyme activities in rats fed baobab seed oil containing Cyclopropenoid Fatty Acids
Food and Chemical Toxicology, 1995Co-Authors: A A Andrianaivorafehivola, Mariehelene Siess, E M GaydouAbstract:Abstract The effects on drug metabolizing enzymes of Cyclopropenoid Fatty Acids present in baobab seed oil were evaluated in rats fed either a diet with baobab seed oil (1.27% Cyclopropenoid Fatty Acids in the diet) or a diet with heated baobab seed oil (0.046% Cyclopropenoid Fatty Acids in the diet). Comparison was made with rats fed a mixture of oils that contained no Cyclopropenoid Fatty acid. Rats fed baobab oil showed retarded growth. In comparison with the other groups, the relative liver weights were markedly increased whereas cytochrome P -450 content and NADPH cytochrome c reductase and NADH cytochrome c reductase activities were decreased. In rats fed the heated baobab oil the relative liver weight was decreased and the cytochrome P -450 level and reductase activities were increased relative to levels in rats fed the unheated oil. Ethoxycoumarin deethylase, ethoxyresorufin deethylase and pentoxyresorufin depentylase activities, expressed on the basis of cytochrome P -450, were greater in the group fed unheated baobab seed oil. Cytosolic glutathione transferase activity was markedly decreased in rats fed fresh baobab seed oil and heating the oil, which reduced the content of Cyclopropenoid Fatty Acids, led to a considerable increase of this activity. UDP-glucuronyl transferase activities were not modified by the type of oil included in the diet. It is possible that the mechanisms of action of Cyclopropenoid Fatty Acids are related to alterations of membrane lipid composition or microsomal proteins.
Kallappa M. Hosamani - One of the best experts on this subject based on the ideXlab platform.
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industrial utilization of triumfetta pilosa roth seed oil a moderate source of oil and Cyclopropenoid Fatty Acids
Industrial Crops and Products, 2003Co-Authors: Kallappa M. Hosamani, H S RameshAbstract:Abstract Triumfetta pilosa contain malvalic acid (2.4%) and sterculic acid (6.6%) along with the other normal Fatty Acids like palmitic (16.7%), stearic (10.8%), oleic (20.1%) and linoleic (43.4%). The Cyclopropenoid (malvalic and sterculic) and other normal Fatty Acids have been determined by FTIR, 1H NMR, gas liquid chromatographic-techniques and chemical degradations.
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Unique occurrence of unusual Fatty Acids and their industrial utilization
Industrial & Engineering Chemistry Research, 1996Co-Authors: Kallappa M. HosamaniAbstract:Ebenaceae plant family consists of 7 genera and more than 320 species. The present investigation describes the unique occurrence of hitherto unknown 9-keto-cis-13-octadecenoic acid (29.0%) and the Cyclopropenoid Fatty Acids (malvalic acid 12.7% and sterculic acid 8.7%) in the seed oil of Diospyros melanoxylon as well as in the Ebenaceae plant family. Other normal Fatty Acids are also detected. The identification and characterization were based on FTIR, 1H NMR, 13C NMR, MS, and GLC techniques and chemical degradations.
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epoxy and Cyclopropenoid Fatty Acids in amaranthus paniculatus seed oil
Journal of the Science of Food and Agriculture, 1992Co-Authors: Chirag Mahmood, Jehan D Daulatabad, Kallappa M. HosamaniAbstract:Amaranthus paniculatus (L) syn Amaranthus caudatus, (L) seed oil contains palmitic (19-4%), stearic (3-9%), oleic (21-9%), linoleic (43-9%), vernolic (7-8%), malvalic (1-5%) and sterculic (1-6%) Acids. These Fatty Acids were characterised by IR, NMR, MS and GLC techniques and by chemical degradations.
John Shanklin - One of the best experts on this subject based on the ideXlab platform.
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Characterization and analysis of the cotton cyclopropane Fatty acid synthase family and their contribution to cyclopropane Fatty acid synthesis.
BMC Plant Biology, 2011Co-Authors: Xiao-hong Yu, Richa Rawat, John ShanklinAbstract:Background Cyclopropane Fatty Acids (CPA) have been found in certain gymnosperms, Malvales, Litchi and other Sapindales. The presence of their unique strained ring structures confers physical and chemical properties characteristic of unsaturated Fatty Acids with the oxidative stability displayed by saturated Fatty Acids making them of considerable industrial interest. While Cyclopropenoid Fatty Acids (CPE) are well-known inhibitors of Fatty acid desaturation in animals, CPE can also inhibit the stearoyl-CoA desaturase and interfere with the maturation and reproduction of some insect species suggesting that in addition to their traditional role as storage lipids, CPE can contribute to the protection of plants from herbivory.
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Characterization and analysis of the cotton cyclopropane Fatty acid synthase family and their contribution to cyclopropane Fatty acid synthesis
BMC Plant Biology, 2011Co-Authors: Xiao-hong Yu, Richa Rawat, John ShanklinAbstract:Background Cyclopropane Fatty Acids (CPA) have been found in certain gymnosperms, Malvales, Litchi and other Sapindales. The presence of their unique strained ring structures confers physical and chemical properties characteristic of unsaturated Fatty Acids with the oxidative stability displayed by saturated Fatty Acids making them of considerable industrial interest. While Cyclopropenoid Fatty Acids (CPE) are well-known inhibitors of Fatty acid desaturation in animals, CPE can also inhibit the stearoyl-CoA desaturase and interfere with the maturation and reproduction of some insect species suggesting that in addition to their traditional role as storage lipids, CPE can contribute to the protection of plants from herbivory. Results Three genes encoding cyclopropane synthase homologues GhCPS1, GhCPS2 and GhCPS3 were identified in cotton. Determination of gene transcript abundance revealed differences among the expression of GhCPS1, 2 and 3 showing high, intermediate and low levels, respectively, of transcripts in roots and stems; whereas GhCPS1 and 2 are both expressed at low levels in seeds. Analyses of Fatty acid composition in different tissues indicate that the expression patterns of GhCPS1 and 2 correlate with cyclic Fatty acid (CFA) distribution. Deletion of the N-terminal oxidase domain lowered GhCPS's ability to produce cyclopropane Fatty acid by approximately 70%. GhCPS1 and 2, but not 3 resulted in the production of cyclopropane Fatty Acids upon heterologous expression in yeast, tobacco BY2 cell and Arabidopsis seed. Conclusions In cotton GhCPS1 and 2 gene expression correlates with the total CFA content in roots, stems and seeds. That GhCPS1 and 2 are expressed at a similar level in seed suggests both of them can be considered potential targets for gene silencing to reduce undesirable seed CPE accumulation. Because GhCPS1 is more active in yeast than the published Sterculia CPS and shows similar activity when expressed in model plant systems, it represents a strong candidate gene for CFA accumulation via heterologous expression in production plants.
