The Experts below are selected from a list of 261 Experts worldwide ranked by ideXlab platform
Kiyohisa Takahashi - One of the best experts on this subject based on the ideXlab platform.
-
Cortical regional differences of Delta Waves during all-night sleep in schizophrenia.
Schizophrenia Research, 2010Co-Authors: Masanori Sekimoto, Masaaki Kato, Tsuyoshi Watanabe, Naofumi Kajimura, Kiyohisa TakahashiAbstract:Abstract Background Delta sleep is mediated by thalamocortical circuits and is postulated to be abnormal in schizophrenia. Delta Wave deficits during sleep have been observed in patients with schizophrenia. Negative symptoms have been reported to reflect frontal lobe dysfunction and to be associated with decreased Delta Wave sleep. This investigation was undertaken to identify cortical functional abnormalities in patients with schizophrenia shown on the electroencephalogram. Methods We compared seventeen male, medically treated or neuroleptic-naive outpatients with schizophrenia and 18 healthy male volunteers by all-night polysomnography and investigated cortical regional differences of Delta Waves. All-night sleep data was evaluated by period amplitude analyses. Delta Waves during sleep were investigated in bilateral frontal, central, parietal, and occipital regions by computer analysis. The associations between Delta Waves in all regions and measures of clinical variables were also estimated. Results Patients with schizophrenia showed lower total Delta Wave counts during all-night sleep than did control subjects in all regions. Control subjects showed significantly higher Delta Wave counts in the right frontal and central region than in the left, which was not observed in patients with schizophrenia. Significant inverse correlations were observed between negative symptom scores and Delta Wave counts in all regions. Control subjects showed significant inverse correlations between Delta Wave counts and age, which were not identified in patients with schizophrenia. Conclusions Delta Wave deficits in all regions may reflect thalamocortical dysfunction in schizophrenia. Reduced right frontal and central Delta Wave dominance is suggested to be involved in the pathophysiology of schizophrenia.
-
Cortical regional differences of Delta Waves during all-night sleep in schizophrenia.
Schizophrenia research, 2010Co-Authors: Masanori Sekimoto, Masaaki Kato, Tsuyoshi Watanabe, Naofumi Kajimura, Kiyohisa TakahashiAbstract:Delta sleep is mediated by thalamocortical circuits and is postulated to be abnormal in schizophrenia. Delta Wave deficits during sleep have been observed in patients with schizophrenia. Negative symptoms have been reported to reflect frontal lobe dysfunction and to be associated with decreased Delta Wave sleep. This investigation was undertaken to identify cortical functional abnormalities in patients with schizophrenia shown on the electroencephalogram. We compared seventeen male, medically treated or neuroleptic-naive outpatients with schizophrenia and 18 healthy male volunteers by all-night polysomnography and investigated cortical regional differences of Delta Waves. All-night sleep data was evaluated by period amplitude analyses. Delta Waves during sleep were investigated in bilateral frontal, central, parietal, and occipital regions by computer analysis. The associations between Delta Waves in all regions and measures of clinical variables were also estimated. Patients with schizophrenia showed lower total Delta Wave counts during all-night sleep than did control subjects in all regions. Control subjects showed significantly higher Delta Wave counts in the right frontal and central region than in the left, which was not observed in patients with schizophrenia. Significant inverse correlations were observed between negative symptom scores and Delta Wave counts in all regions. Control subjects showed significant inverse correlations between Delta Wave counts and age, which were not identified in patients with schizophrenia. Delta Wave deficits in all regions may reflect thalamocortical dysfunction in schizophrenia. Reduced right frontal and central Delta Wave dominance is suggested to be involved in the pathophysiology of schizophrenia. Copyright © 2010 Elsevier B.V. All rights reserved.
-
Reduced Frontal Asymmetry of Delta Waves During All-Night Sleep in Schizophrenia
Schizophrenia bulletin, 2006Co-Authors: Masanori Sekimoto, Masaaki Kato, Tsuyoshi Watanabe, Naofumi Kajimura, Kiyohisa TakahashiAbstract:Delta Wave deficits during sleep have been observed in patients with schizophrenia. Decreased slow-Wave sleep is reported to be associated with negative symptoms. Frontal lobe dysfunction is also believed to underlie negative symptoms of schizophrenia. This study was designed to identify functional abnormalities in schizophrenia manifested on patients' electroencephalograms. Polysomnograph examinations were performed in 12 healthy male volunteers and 11 male outpatients with schizophrenia. We investigated the laterality of frontal cortical Delta Waves in patients with schizophrenia and in healthy control subjects. Laterality of frontal cortex Delta Wave counts during all-night sleep was investigated by computer analysis. Total Delta Wave counts were lower in patients with schizophrenia than in control subjects. Control subjects showed significantly higher Delta Wave counts in the right frontal cortex than in the left. This asymmetry was not observed in patients with schizophrenia. These findings suggest that reduced right frontal Delta Wave dominance is involved in the pathophysiology of schizophrenia.
Soichiro Nomura - One of the best experts on this subject based on the ideXlab platform.
-
Electroconvulsive therapy-induced Wolff–Parkinson–White syndrome: a case report
General hospital psychiatry, 2013Co-Authors: Shingo Enomoto, Aihide Yoshino, Bonpei Takase, Tatsuro Kuwahara, Yasutaka Tatsuzawa, Soichiro NomuraAbstract:Abstract Objective Wolff–Parkinson–White (WPW) syndrome is characterized by premature ventricular excitation due to the presence of an abnormal accessory pathway. Electrocardiography (ECG) of patients with WPW syndrome portrays a short PR interval and a wide QRS interval with a Delta Wave. Methods Herein, we report the case of a patient with schizophrenia who developed a wide QRS interval with a Delta Wave immediately following electroconvulsive therapy (ECT). Results Initially, the Delta Wave disappeared within 2 days after ECT. However, the duration of the Delta Wave increased exponentially to 4 months when ECT was repeated. Conclusion Although the patient's cardiocirculatory dynamics remained normal, we continued to monitor her ECG until the Delta Wave disappeared because WPW syndrome can lead to serious arrhythmia.
Keijiro Nakamura - One of the best experts on this subject based on the ideXlab platform.
-
Abstract 11125: A Novel Algorithm to Distinguish Left-sided Posteroseptal Accessory Pathway and Right-sided Posteroseptal Accessory Pathway Using the Difference in the Beginning of the Delta Wave.
Circulation, 2010Co-Authors: Tatsuya Hayashi, Koji Kumagai, Shigeto Naito, Suguru Nishiuchi, Etsuko Fuke, Chizuru Sato, Yuko Miki, Koji Goto, Tamotsu Sakamoto, Keijiro NakamuraAbstract:Objectives: The purpose of this study is to investigate an algorithm in the prediction of successful radiofrequency (RF) catheter ablation site of the posteroseptal accessory pathway (PSAP) in manifest Wolff-Parkinson-White (WPW) syndrome. Background: Although some algorithm of AP locations have been proposed previously, it remains still challenging to predict the successful ablation site. This is especially true for the PSAPs because it is difficult to distinguish between left-sided and right-sided PSAPs. Methods: Thirty-one patients undergoing ablation of manifest PS-APs were investigated in retrospective analyses. They were divided into two groups; group R: right-sided PSAP (n=23) and group L: left-sided PSAP (n=8). In addition to the conventional electrophysiological parameter, the interval time between the earliest onset of the Delta Wave in inferior leads and latest onset in precordial leads was defined as “Delta-Wave difference” in both groups. On the basis of these results, we evaluated usefulness of “Delta-Wave difference” for the detection of left-sided and right-sided approaches. Results: The Delta-Wave difference was prolonged significantly in the group L compared with the group R (group R: 11±11msec, group L: 29±11msec, p Conclusions: In patients with manifest WPW syndrome using PSAPs, the measurement of “Delta Wave difference” can be a good predictor to determine approach side for the successful ablation.
Chung-yin Chen - One of the best experts on this subject based on the ideXlab platform.
-
An Accurate Stepwise Electrocardiographic Algorithm for localization of Accessory Pathways in Patients With Wolff-Parkinson-White Syndrome from a Comprehensive Analysis of Delta Waves and R/S Ratio During Sinus Rhythm
The American journal of cardiology, 1995Co-Authors: Chern-en Chiang, Shih-ann Chen, W S Teo, Der-shang Tsai, Chen-chuan Cheng, Chuen-wang Chiou, Ching-tai Tai, Shih-huang Lee, Chung-yin ChenAbstract:Prediction of accessory pathway location before radio-frequency ablation has become increasingly important for patients with Wolff-Parkinson-White syndrome. However, existing electrocardiographic (ECG) criteria for localization of accessory pathways have several limitations, and the polarity of Delta Waves has not been well defined. In the present study, 369 patients with a single anterogradely conducting accessory pathway who underwent successful radiofrequency ablation were included. The polarity of Delta Waves was defined and categorized in detail, and various ECG characteristics of the most preexcited QRS complexes were examined and compared with QRS complexes after successful ablation in the initial 182 patients, which included morphology and polarity of Delta Waves, initial 20, 40, and 60 ms segments of the preexcited QRS complex, R/S ratio in the precordial leads, R/S ratio in the frontal leads, Delta Wave axis in the frontal plane, polarity of Delta Waves in the frontal leads, and polarity of Delta Waves in the precordial leads. The polarity of the initial 40 ms segment of the most preexcited QRS complexes in each of the frontal leads, and the polarity of the initial 60 ms segment of the most preexcited QRS complex in each of the precordial leads proved to be the best representatives of Delta Wave polarity in the respective leads.(ABSTRACT TRUNCATED AT 250 WORDS)
John M. Miller - One of the best experts on this subject based on the ideXlab platform.
-
Pacemap of Delta Wave for successful ablation of traumatized atrioventricular accessory pathway.
Heart rhythm, 2012Co-Authors: Seongwook Han, John M. MillerAbstract:547-5271/$ -see front matter © 2012 Heart Rhythm Society. All rights reserved oss of AP conduction, but it appears that the vast majority of raumatized tissues recover (resumption of conduction) over a eriod ranging from several minutes to months. The ability to elocate the AP in order to complete the ablation procedure is onfounded by the time it takes to recover conduction. If onduction does not resume after mechanical trauma, radiofreuency (RF) ablation at the presumed AP location site may be ssociated with a poor ablation outcome or may lead to iscontinuation of the procedure. Rarely, persisting AP potenials may be used as a guide to ablation. We report a patient who underwent successful ablation of a right lateral AP by using pacemapping of the Delta Wave from the tricuspid annulus (TA) after mechanical trauma had eliminated conduction.