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Shelly Abramowicz - One of the best experts on this subject based on the ideXlab platform.
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medical management of patients undergoing Dentoalveolar Surgery
Oral and Maxillofacial Surgery Clinics of North America, 2015Co-Authors: Shelly Abramowicz, Steven M RoserAbstract:: The oral and maxillofacial surgeon (OMS) should have an understanding of common medical comorbidities. This understanding allows for risk stratification and thus prevention of potential problems. Remaining knowledgeable regarding diseases, diagnosis, treatment strategies, and pharmacology ultimately improves patient care. This article provides an update on some of the most common medical diseases for the patient undergoing Dentoalveolar Surgery.
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pediatric Dentoalveolar Surgery
Dental Clinics of North America, 2012Co-Authors: Sean W Digman, Shelly AbramowiczAbstract:Dentoalveolar Surgery in children presents general dentists with unique challenges not encountered in adults. The long-term effects that treatments have on these children must always be taken into consideration. A clear understanding of the growth and development of pediatric patients is necessary to correctly identify dental abnormalities. The tooth bud is a collection of cells derived from the ectoderm of the first brachial arch and the ectomesenchyme of the neural crest cells. The formation of primary teeth is evident between 6 and 8 weeks in utero and the permanent teeth form in the twen- tieth week. The initial calcification of the primary teeth ranges from 14 weeks for the incisors to 19 weeks for the second molars. The permanent incisors calcify between age 3 and 4 months and the third molars calcify between 7 and 10 years. If the denti- tion does not develop at these times or there is an event that disrupts the formation, then tooth development ceases. The most common congenitally missing teeth are the third molars followed by the lateral incisors and the mandibular second premolars. The eruption pattern of the primary and permanent dentition is of critical importance (Table 1). If a tooth or teeth fail to erupt, the cause should be investigated. Possible reasons include but are not limited to tooth malposition, retained primary teeth, arch space/length discrepancies, obstruction by a supernumerary tooth or a cyst (usually seen in teens, such as keratocysts and dentigerous cysts), or tumors (usually seen in childhood, such as compound/complex odontomas and fibro-osseous lesions). An anomaly in dental growth and development may be indicative of a more ominous
Klaus Pelz - One of the best experts on this subject based on the ideXlab platform.
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bacterial colonization on different suture materials a potential risk for intraoral Dentoalveolar Surgery
Journal of Biomedical Materials Research Part B, 2005Co-Authors: Jorgelard Otten, M Wiedmannalahmad, H Jahnke, Klaus PelzAbstract:In this in vivo and in vitro study on resorbable (Monocryl®) and nonresorbable (Deknalon®) monofilament sutures used in intraoral Dentoalveolar Surgery the bacterial colonization was compared. For the in vivo study the sutures were applied in 11 patients during dental Surgery. Eight days postoperative the sutures were removed and the adhered bacteria were isolated and identified by biochemistry, morphology, antibiotic susceptibility, and gaschromatography. The colonization was studied by scanning electron microscopy. Aerobic and anaerobic bacteria were isolated in nearly equal colony-forming units (cfu) on each suture. In comparison with Monocryl® about 15% more aerobic and anaerobic strains were isolated on Deknalon®. Regarding the pathogens only, about three times more anaerobic strains were isolated on both sutures in total. Additionally, more pathogens were found on Deknalon® than on Monocryl® (aerobic >40%, anaerobic >25%). The variety of bacteria correspond with purulent infections, not with normal oral flora. Intraindividual comparisons of cfu showed differences in dependence of the patient as described for subgingivale plaques. For the in vitro study the sutures were incubated with Streptococcus intermedius and Prevotella intermedia for 0.5 h. Scanning electron microscopy was performed to examine qualitatively the level of bacterial adherence. After 0.5 h the bacteria adhered very well. The colonization rate of Streptococcus intermedius on both sutures was similar. Coccoid bacteria within biofilms were seen. The growth of Prevotella intermedia was much better on Deknalon® than on Monocryl®. The risk of bacteremia at the time of suture removal is discussed. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2005
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bacterial colonization on different suture materials a potential risk for intraoral Dentoalveolar Surgery
Journal of Biomedical Materials Research, 2005Co-Authors: Jorgelard Otten, M Wiedmannalahmad, H Jahnke, Klaus PelzAbstract:In this in vivo and in vitro study on resorbable (Monocryl®) and nonresorbable (Deknalon®) monofilament sutures used in intraoral Dentoalveolar Surgery the bacterial colonization was compared. For the in vivo study the sutures were applied in 11 patients during dental Surgery. Eight days postoperative the sutures were removed and the adhered bacteria were isolated and identified by biochemistry, morphology, antibiotic susceptibility, and gaschromatography. The colonization was studied by scanning electron microscopy. Aerobic and anaerobic bacteria were isolated in nearly equal colony-forming units (cfu) on each suture. In comparison with Monocryl® about 15% more aerobic and anaerobic strains were isolated on Deknalon®. Regarding the pathogens only, about three times more anaerobic strains were isolated on both sutures in total. Additionally, more pathogens were found on Deknalon® than on Monocryl® (aerobic >40%, anaerobic >25%). The variety of bacteria correspond with purulent infections, not with normal oral flora. Intraindividual comparisons of cfu showed differences in dependence of the patient as described for subgingivale plaques. For the in vitro study the sutures were incubated with Streptococcus intermedius and Prevotella intermedia for 0.5 h. Scanning electron microscopy was performed to examine qualitatively the level of bacterial adherence. After 0.5 h the bacteria adhered very well. The colonization rate of Streptococcus intermedius on both sutures was similar. Coccoid bacteria within biofilms were seen. The growth of Prevotella intermedia was much better on Deknalon® than on Monocryl®. The risk of bacteremia at the time of suture removal is discussed.
Jorgelard Otten - One of the best experts on this subject based on the ideXlab platform.
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bacterial colonization on different suture materials a potential risk for intraoral Dentoalveolar Surgery
Journal of Biomedical Materials Research Part B, 2005Co-Authors: Jorgelard Otten, M Wiedmannalahmad, H Jahnke, Klaus PelzAbstract:In this in vivo and in vitro study on resorbable (Monocryl®) and nonresorbable (Deknalon®) monofilament sutures used in intraoral Dentoalveolar Surgery the bacterial colonization was compared. For the in vivo study the sutures were applied in 11 patients during dental Surgery. Eight days postoperative the sutures were removed and the adhered bacteria were isolated and identified by biochemistry, morphology, antibiotic susceptibility, and gaschromatography. The colonization was studied by scanning electron microscopy. Aerobic and anaerobic bacteria were isolated in nearly equal colony-forming units (cfu) on each suture. In comparison with Monocryl® about 15% more aerobic and anaerobic strains were isolated on Deknalon®. Regarding the pathogens only, about three times more anaerobic strains were isolated on both sutures in total. Additionally, more pathogens were found on Deknalon® than on Monocryl® (aerobic >40%, anaerobic >25%). The variety of bacteria correspond with purulent infections, not with normal oral flora. Intraindividual comparisons of cfu showed differences in dependence of the patient as described for subgingivale plaques. For the in vitro study the sutures were incubated with Streptococcus intermedius and Prevotella intermedia for 0.5 h. Scanning electron microscopy was performed to examine qualitatively the level of bacterial adherence. After 0.5 h the bacteria adhered very well. The colonization rate of Streptococcus intermedius on both sutures was similar. Coccoid bacteria within biofilms were seen. The growth of Prevotella intermedia was much better on Deknalon® than on Monocryl®. The risk of bacteremia at the time of suture removal is discussed. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2005
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bacterial colonization on different suture materials a potential risk for intraoral Dentoalveolar Surgery
Journal of Biomedical Materials Research, 2005Co-Authors: Jorgelard Otten, M Wiedmannalahmad, H Jahnke, Klaus PelzAbstract:In this in vivo and in vitro study on resorbable (Monocryl®) and nonresorbable (Deknalon®) monofilament sutures used in intraoral Dentoalveolar Surgery the bacterial colonization was compared. For the in vivo study the sutures were applied in 11 patients during dental Surgery. Eight days postoperative the sutures were removed and the adhered bacteria were isolated and identified by biochemistry, morphology, antibiotic susceptibility, and gaschromatography. The colonization was studied by scanning electron microscopy. Aerobic and anaerobic bacteria were isolated in nearly equal colony-forming units (cfu) on each suture. In comparison with Monocryl® about 15% more aerobic and anaerobic strains were isolated on Deknalon®. Regarding the pathogens only, about three times more anaerobic strains were isolated on both sutures in total. Additionally, more pathogens were found on Deknalon® than on Monocryl® (aerobic >40%, anaerobic >25%). The variety of bacteria correspond with purulent infections, not with normal oral flora. Intraindividual comparisons of cfu showed differences in dependence of the patient as described for subgingivale plaques. For the in vitro study the sutures were incubated with Streptococcus intermedius and Prevotella intermedia for 0.5 h. Scanning electron microscopy was performed to examine qualitatively the level of bacterial adherence. After 0.5 h the bacteria adhered very well. The colonization rate of Streptococcus intermedius on both sutures was similar. Coccoid bacteria within biofilms were seen. The growth of Prevotella intermedia was much better on Deknalon® than on Monocryl®. The risk of bacteremia at the time of suture removal is discussed.
David Dohan M Ehrenfest - One of the best experts on this subject based on the ideXlab platform.
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current knowledge and perspectives for the use of platelet rich plasma prp and platelet rich fibrin prf in oral and maxillofacial Surgery part 1 periodontal and Dentoalveolar Surgery
Current Pharmaceutical Biotechnology, 2012Co-Authors: Marco Del Corso, Alain Vervelle, Alain Simonpieri, Ryo Jimbo, Francesco Inchingolo, Gilberto Sammartino, David Dohan M EhrenfestAbstract:Platelet concentrates for surgical use are innovative tools of regenerative medicine, and were widely tested in oral and maxillofacial Surgery. Unfortunately, the literature on the topic is contradictory and the published data are difficult to sort and interpret. In periodontology and Dentoalveolar Surgery, the literature is particularly dense about the use of the various forms of Platelet-Rich Plasma (PRP) - Pure Platelet-Rich Plasma (P-PRP) or Leukocyte- and Platelet-Rich Plasma (L-PRP) - but still limited about Platelet-Rich Fibrin (PRF) subfamilies. In this first article, we describe and discuss the current published knowledge about the use of PRP and PRF during tooth avulsion or extraction, mucogingival Surgery, Guided Tissue Regeneration (GTR) or bone filling of periodontal intrabony defects, and regeneration of alveolar ridges using Guided Bone Regeneration (GBR), in a comprehensive way and in order to avoid the traps of a confusing literature and to highlight the underlying universal mechanisms of these products. Finally, we particularly insist on the perspectives in this field, through the description and illustration of the systematic use of L-PRF (Leukocyte- and Platelet- Rich Fibrin) clots and membranes during tooth avulsion, cyst exeresis or the treatment of gingival recessions by root coverage. The use of L-PRF also allowed to define new therapeutic principles: NTR (Natural Tissue Regeneration) for the treatment of periodontal intrabony lesions and Natural Bone Regeneration (NBR) for the reconstruction of the alveolar ridges. In periodontology, this field of research will soon find his golden age by the development of user-friendly platelet concentrate procedures, and the definition of new efficient concepts and clinical protocols.
Carlo Maiorana - One of the best experts on this subject based on the ideXlab platform.
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adjunctive application of antimicrobial photodynamic therapy in the prevention of medication related osteonecrosis of the jaw following Dentoalveolar Surgery a case series
Photodiagnosis and Photodynamic Therapy, 2019Co-Authors: Pier Paolo Poli, F A Souza, Susanna Ferrario, Carlo MaioranaAbstract:Abstract Background Medication-related osteonecrosis of the jaw (MRONJ) is a debilitating complication strongly associated to antiresorptive agents. The present study aimed to describe the use of antimicrobial photodynamic therapy (aPDT) in the prevention of MRONJ. Methods The sample consisted of 11 non-oncologic osteoporotic subjects in therapy with non-intravenous antiresorptive agents, requiring tooth extractions and/or implant removal. After minimally invasive surgical extractions, each alveolar socket was debrided and bony edges were smoothened. At this point, aPDT was performed using methylene blue-based phenothiazine chloride dye irradiated with a hand-held 100 mW diode laser with a wavelength of 660 ± 10 nm. Flaps were sutured to achieve first intention closure. Soft tissue healing was promoted with weekly applications of low-level laser therapy for 6 weeks. Recall visits were scheduled weekly for the first two months and monthly thereafter up to 6 months. At the 6-month appointment, healing was assessed clinically and radiographically. Results A total of 62 surgical extractions were performed in both jaws, including 51 natural elements and 11 dental implants. No intraoperative complications were observed. Immediate post-operative period was generally uneventful except for mild pain and ecchymosis that occurred rarely and resolved spontaneously. Healing proceeded uneventfully, with no clinical or radiological prodromal manifestations of MRONJ up to the latest follow-up visit. Conclusions aPDT might constitute a promising preventive treatment to reduce the risk of MRONJ in non-oncologic osteoporotic patients treated with non-intravenous antiresorptive agents that underwent Dentoalveolar Surgery.