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Vivi Schlünssen - One of the best experts on this subject based on the ideXlab platform.
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non malignant respiratory diseases and occupational Exposure to wood Dust part ii dry wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews the literature on associations between dry wood Dust ex- posure and non-malignant respiratory diseases. Criteria for inclusion are epidemiological studies in English language journals with an internal or external control group describing relationships between dry wood Dust Exposure and respiratory diseases or symptoms. Papers took into consideration smoking and when dealing with lung function age. A total of 37 papers forms the basis of this review. The results support an association between dry wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between wood Dust Exposure and rhino-conjunctivitis is seen across the studies. Apart from plicatic acid in western red cedar wood, no causal agent has consistently been disclosed. Type 1 allergy
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non malignant respiratory diseases and occupational Exposure to wood Dust part i fresh wood and mixed wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews associations in literature between Exposure to wood Dust from fresh wood and non-malignant respiratory diseases. Criteria for inclusion are epi- demiological studies in English language journals with an internal or external control group describing relationships between wood Dust Exposure and respiratory diseases or symptoms. The papers took into account smoking, and when dealing with lung function took age into consideration. A total of 25 papers concerning Exposure to fresh wood and mixed wood formed the basis of this review. The results support an association between fresh wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between fresh wood Dust Exposure and rhino-conjunctivitis was seen across studies. Apart from plicatic acid in western red cedar wood, no causal agent was consistently disclosed. Type 1 allergy is not suspected of being a major cause of wood Dust induced asthma. Concurrent Exposure to microorganisms and terpenes probably add to the inherent risk of wood Dust Exposure in the fresh wood inDustry.
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increased incidence of respiratory symptoms among female woodworkers exposed to dry wood
European Respiratory Journal, 2009Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, Torben SigsgaardAbstract:The aim of the present study was to investigate the occurrence of new respiratory symptoms in relation to wood Dust Exposure in a 6-yr follow-up study. A total of 1,377 woodworkers (1,137 males; 240 females) and 297 reference workers (137 males; 160 females) participated. Data on respiratory symptoms, employment and smoking habits were collected. Wood Dust Exposure was assessed from baseline Dust measurements, and cumulative wood Dust Exposure was assessed by study-specific job Exposure matrices and Exposure time. The geometric mean (geometric sd) Dust level decreased during the study period from 0.94 (2.1) to 0.60 (1.6) mg·m−3. Adjusted analysis revealed positive associations for cumulative incidence proportion of chronic bronchitis and daily coughing for female woodworkers versus female reference workers. The cumulative incidence proportion of daily coughing and chronic bronchitis were found to be associated with baseline wood Dust Exposure in a dose-dependent manner. The odds ratio (95% confidence interval) for daily coughing (with reference to the lowest Exposure quartile) was 1.6 (0.6–4.3), 3.2 (0.9–6.8) and 3.8 (1.5–9.7), respectively, in the second and third lowest and the highest quartile. The figures for chronic bronchitis were, accordingly, 2.3 (0.4–14.5), 3.0 (0.5–18.7) and 6.0 (1.2–28.8). In conclusion, female woodworkers in this low Exposure cohort showed an increased incidence of coughing and bronchitis, whereas no relations to wood Dust Exposure were seen for male woodworkers.
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longitudinal lung function decline and wood Dust Exposure in the furniture inDustry
European Respiratory Journal, 2008Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:The aim of the present study was to investigate the relationship between change in lung function and cumulative Exposure to wood Dust. In total, 1,112 woodworkers (927 males, 185 females) and 235 reference workers (104 males, 185 females) participated in a 6-yr longitudinal study. Forced expiratory volume in one second (FEV(1)), forced vital capacity (FVC), height and weight were measured, and questionnaire data on respiratory symptoms, wood Dust Exposure and smoking habits were collected. Cumulative inhalable wood Dust Exposure was assessed using a study-specific job Exposure matrix and Exposure time. The median (range) for cumulative wood Dust Exposure was 3.75 (0-7.55) mg x year x m(-3). A dose-response relationship between cumulative wood Dust Exposure and percent annual decrease in FEV(1) was suggested for female workers. This was confirmed in a linear regression model adjusted for confounders, including smoking, height and age. An additional difference of -14.50 mL x yr(-1) and -27.97 mL x yr(-1) was revealed for females exposed to 3.75-4.71 mg x yr x m(-3) or to >4.71 mg x yr x m(-3), respectively, compared with non-/low-exposed females. For females, a positive trend between wood Dust Exposure and the cumulative incidence proportion of FEV(1)/FVC <70% was suggested. In conclusion, in the present low-exposed cohort, female woodworkers had an accelerated decline in lung function, which may be clinically relevant.
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Indices of asthma among atopic and non-atopic woodworkers.
Occupational and environmental medicine, 2004Co-Authors: Vivi Schlünssen, Dick Heederik, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:Aims: To investigate the relation between wood Dust Exposure and different indices of asthma among woodworkers and non-exposed subjects. Methods: A total of 302 woodworkers and 71 non-exposed subjects answered a respiratory health questionnaire, underwent a non-specific bronchial provocation test using the Yan method, and received a skin prick test with 12 common inhalant allergens. Subgroups performed repeated peak flow monitoring and underwent a reversibility test. A total of 347 Dust measurements among 234 woodworkers were performed with passive Dust monitors. Results: The overall geometric mean (geometric standard deviation) Exposure to inhalable Dust was 0.96 (2.02) mg/m3. There was a tendency to increased risk of asthma among atopic woodworkers compared to atopic non-exposed subjects, with ORs between 3.0 (0.8–11.9) (symptomatic BHR) and 1.3 (0.5–4.2) (work related symptoms). In woodworkers, asthma was associated with atopy, with ORs between 7.4 (2.8–19.7) (symptomatic BHR) and 4.2 (2.4–7.7) (asthma symptoms). Asthma was related to Dust level, most pronounced for symptomatic BHR among atopics, with OR 22.9 (1.0–523.6) for the highest compared to the lowest Dust level. For work related asthma symptoms the association with Dust level was seen only for non-atopics. Conclusions: Wood Dust Exposure was associated with asthma, despite a low Dust level compared to other studies. Atopy was an important effect modifier in the association between asthma and wood Dust Exposure.
Torben Sigsgaard - One of the best experts on this subject based on the ideXlab platform.
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non malignant respiratory diseases and occupational Exposure to wood Dust part i fresh wood and mixed wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews associations in literature between Exposure to wood Dust from fresh wood and non-malignant respiratory diseases. Criteria for inclusion are epi- demiological studies in English language journals with an internal or external control group describing relationships between wood Dust Exposure and respiratory diseases or symptoms. The papers took into account smoking, and when dealing with lung function took age into consideration. A total of 25 papers concerning Exposure to fresh wood and mixed wood formed the basis of this review. The results support an association between fresh wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between fresh wood Dust Exposure and rhino-conjunctivitis was seen across studies. Apart from plicatic acid in western red cedar wood, no causal agent was consistently disclosed. Type 1 allergy is not suspected of being a major cause of wood Dust induced asthma. Concurrent Exposure to microorganisms and terpenes probably add to the inherent risk of wood Dust Exposure in the fresh wood inDustry.
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non malignant respiratory diseases and occupational Exposure to wood Dust part ii dry wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews the literature on associations between dry wood Dust ex- posure and non-malignant respiratory diseases. Criteria for inclusion are epidemiological studies in English language journals with an internal or external control group describing relationships between dry wood Dust Exposure and respiratory diseases or symptoms. Papers took into consideration smoking and when dealing with lung function age. A total of 37 papers forms the basis of this review. The results support an association between dry wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between wood Dust Exposure and rhino-conjunctivitis is seen across the studies. Apart from plicatic acid in western red cedar wood, no causal agent has consistently been disclosed. Type 1 allergy
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increased incidence of respiratory symptoms among female woodworkers exposed to dry wood
European Respiratory Journal, 2009Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, Torben SigsgaardAbstract:The aim of the present study was to investigate the occurrence of new respiratory symptoms in relation to wood Dust Exposure in a 6-yr follow-up study. A total of 1,377 woodworkers (1,137 males; 240 females) and 297 reference workers (137 males; 160 females) participated. Data on respiratory symptoms, employment and smoking habits were collected. Wood Dust Exposure was assessed from baseline Dust measurements, and cumulative wood Dust Exposure was assessed by study-specific job Exposure matrices and Exposure time. The geometric mean (geometric sd) Dust level decreased during the study period from 0.94 (2.1) to 0.60 (1.6) mg·m−3. Adjusted analysis revealed positive associations for cumulative incidence proportion of chronic bronchitis and daily coughing for female woodworkers versus female reference workers. The cumulative incidence proportion of daily coughing and chronic bronchitis were found to be associated with baseline wood Dust Exposure in a dose-dependent manner. The odds ratio (95% confidence interval) for daily coughing (with reference to the lowest Exposure quartile) was 1.6 (0.6–4.3), 3.2 (0.9–6.8) and 3.8 (1.5–9.7), respectively, in the second and third lowest and the highest quartile. The figures for chronic bronchitis were, accordingly, 2.3 (0.4–14.5), 3.0 (0.5–18.7) and 6.0 (1.2–28.8). In conclusion, female woodworkers in this low Exposure cohort showed an increased incidence of coughing and bronchitis, whereas no relations to wood Dust Exposure were seen for male woodworkers.
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longitudinal lung function decline and wood Dust Exposure in the furniture inDustry
European Respiratory Journal, 2008Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:The aim of the present study was to investigate the relationship between change in lung function and cumulative Exposure to wood Dust. In total, 1,112 woodworkers (927 males, 185 females) and 235 reference workers (104 males, 185 females) participated in a 6-yr longitudinal study. Forced expiratory volume in one second (FEV(1)), forced vital capacity (FVC), height and weight were measured, and questionnaire data on respiratory symptoms, wood Dust Exposure and smoking habits were collected. Cumulative inhalable wood Dust Exposure was assessed using a study-specific job Exposure matrix and Exposure time. The median (range) for cumulative wood Dust Exposure was 3.75 (0-7.55) mg x year x m(-3). A dose-response relationship between cumulative wood Dust Exposure and percent annual decrease in FEV(1) was suggested for female workers. This was confirmed in a linear regression model adjusted for confounders, including smoking, height and age. An additional difference of -14.50 mL x yr(-1) and -27.97 mL x yr(-1) was revealed for females exposed to 3.75-4.71 mg x yr x m(-3) or to >4.71 mg x yr x m(-3), respectively, compared with non-/low-exposed females. For females, a positive trend between wood Dust Exposure and the cumulative incidence proportion of FEV(1)/FVC <70% was suggested. In conclusion, in the present low-exposed cohort, female woodworkers had an accelerated decline in lung function, which may be clinically relevant.
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Indices of asthma among atopic and non-atopic woodworkers.
Occupational and environmental medicine, 2004Co-Authors: Vivi Schlünssen, Dick Heederik, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:Aims: To investigate the relation between wood Dust Exposure and different indices of asthma among woodworkers and non-exposed subjects. Methods: A total of 302 woodworkers and 71 non-exposed subjects answered a respiratory health questionnaire, underwent a non-specific bronchial provocation test using the Yan method, and received a skin prick test with 12 common inhalant allergens. Subgroups performed repeated peak flow monitoring and underwent a reversibility test. A total of 347 Dust measurements among 234 woodworkers were performed with passive Dust monitors. Results: The overall geometric mean (geometric standard deviation) Exposure to inhalable Dust was 0.96 (2.02) mg/m3. There was a tendency to increased risk of asthma among atopic woodworkers compared to atopic non-exposed subjects, with ORs between 3.0 (0.8–11.9) (symptomatic BHR) and 1.3 (0.5–4.2) (work related symptoms). In woodworkers, asthma was associated with atopy, with ORs between 7.4 (2.8–19.7) (symptomatic BHR) and 4.2 (2.4–7.7) (asthma symptoms). Asthma was related to Dust level, most pronounced for symptomatic BHR among atopics, with OR 22.9 (1.0–523.6) for the highest compared to the lowest Dust level. For work related asthma symptoms the association with Dust level was seen only for non-atopics. Conclusions: Wood Dust Exposure was associated with asthma, despite a low Dust level compared to other studies. Atopy was an important effect modifier in the association between asthma and wood Dust Exposure.
Inger Schaumburg - One of the best experts on this subject based on the ideXlab platform.
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non malignant respiratory diseases and occupational Exposure to wood Dust part ii dry wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews the literature on associations between dry wood Dust ex- posure and non-malignant respiratory diseases. Criteria for inclusion are epidemiological studies in English language journals with an internal or external control group describing relationships between dry wood Dust Exposure and respiratory diseases or symptoms. Papers took into consideration smoking and when dealing with lung function age. A total of 37 papers forms the basis of this review. The results support an association between dry wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between wood Dust Exposure and rhino-conjunctivitis is seen across the studies. Apart from plicatic acid in western red cedar wood, no causal agent has consistently been disclosed. Type 1 allergy
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non malignant respiratory diseases and occupational Exposure to wood Dust part i fresh wood and mixed wood inDustry
Annals of Agricultural and Environmental Medicine, 2010Co-Authors: Gitte Jacobsen, Torben Sigsgaard, Inger Schaumburg, Vivi SchlünssenAbstract:This paper reviews associations in literature between Exposure to wood Dust from fresh wood and non-malignant respiratory diseases. Criteria for inclusion are epi- demiological studies in English language journals with an internal or external control group describing relationships between wood Dust Exposure and respiratory diseases or symptoms. The papers took into account smoking, and when dealing with lung function took age into consideration. A total of 25 papers concerning Exposure to fresh wood and mixed wood formed the basis of this review. The results support an association between fresh wood Dust Exposure and asthma, asthma symptoms, coughing, bronchitis, and acute and chronic impairment of lung function. In addition, an association between fresh wood Dust Exposure and rhino-conjunctivitis was seen across studies. Apart from plicatic acid in western red cedar wood, no causal agent was consistently disclosed. Type 1 allergy is not suspected of being a major cause of wood Dust induced asthma. Concurrent Exposure to microorganisms and terpenes probably add to the inherent risk of wood Dust Exposure in the fresh wood inDustry.
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increased incidence of respiratory symptoms among female woodworkers exposed to dry wood
European Respiratory Journal, 2009Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, Torben SigsgaardAbstract:The aim of the present study was to investigate the occurrence of new respiratory symptoms in relation to wood Dust Exposure in a 6-yr follow-up study. A total of 1,377 woodworkers (1,137 males; 240 females) and 297 reference workers (137 males; 160 females) participated. Data on respiratory symptoms, employment and smoking habits were collected. Wood Dust Exposure was assessed from baseline Dust measurements, and cumulative wood Dust Exposure was assessed by study-specific job Exposure matrices and Exposure time. The geometric mean (geometric sd) Dust level decreased during the study period from 0.94 (2.1) to 0.60 (1.6) mg·m−3. Adjusted analysis revealed positive associations for cumulative incidence proportion of chronic bronchitis and daily coughing for female woodworkers versus female reference workers. The cumulative incidence proportion of daily coughing and chronic bronchitis were found to be associated with baseline wood Dust Exposure in a dose-dependent manner. The odds ratio (95% confidence interval) for daily coughing (with reference to the lowest Exposure quartile) was 1.6 (0.6–4.3), 3.2 (0.9–6.8) and 3.8 (1.5–9.7), respectively, in the second and third lowest and the highest quartile. The figures for chronic bronchitis were, accordingly, 2.3 (0.4–14.5), 3.0 (0.5–18.7) and 6.0 (1.2–28.8). In conclusion, female woodworkers in this low Exposure cohort showed an increased incidence of coughing and bronchitis, whereas no relations to wood Dust Exposure were seen for male woodworkers.
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longitudinal lung function decline and wood Dust Exposure in the furniture inDustry
European Respiratory Journal, 2008Co-Authors: Gitte Jacobsen, Vivi Schlünssen, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:The aim of the present study was to investigate the relationship between change in lung function and cumulative Exposure to wood Dust. In total, 1,112 woodworkers (927 males, 185 females) and 235 reference workers (104 males, 185 females) participated in a 6-yr longitudinal study. Forced expiratory volume in one second (FEV(1)), forced vital capacity (FVC), height and weight were measured, and questionnaire data on respiratory symptoms, wood Dust Exposure and smoking habits were collected. Cumulative inhalable wood Dust Exposure was assessed using a study-specific job Exposure matrix and Exposure time. The median (range) for cumulative wood Dust Exposure was 3.75 (0-7.55) mg x year x m(-3). A dose-response relationship between cumulative wood Dust Exposure and percent annual decrease in FEV(1) was suggested for female workers. This was confirmed in a linear regression model adjusted for confounders, including smoking, height and age. An additional difference of -14.50 mL x yr(-1) and -27.97 mL x yr(-1) was revealed for females exposed to 3.75-4.71 mg x yr x m(-3) or to >4.71 mg x yr x m(-3), respectively, compared with non-/low-exposed females. For females, a positive trend between wood Dust Exposure and the cumulative incidence proportion of FEV(1)/FVC <70% was suggested. In conclusion, in the present low-exposed cohort, female woodworkers had an accelerated decline in lung function, which may be clinically relevant.
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Indices of asthma among atopic and non-atopic woodworkers.
Occupational and environmental medicine, 2004Co-Authors: Vivi Schlünssen, Dick Heederik, Inger Schaumburg, E Taudorf, Torben SigsgaardAbstract:Aims: To investigate the relation between wood Dust Exposure and different indices of asthma among woodworkers and non-exposed subjects. Methods: A total of 302 woodworkers and 71 non-exposed subjects answered a respiratory health questionnaire, underwent a non-specific bronchial provocation test using the Yan method, and received a skin prick test with 12 common inhalant allergens. Subgroups performed repeated peak flow monitoring and underwent a reversibility test. A total of 347 Dust measurements among 234 woodworkers were performed with passive Dust monitors. Results: The overall geometric mean (geometric standard deviation) Exposure to inhalable Dust was 0.96 (2.02) mg/m3. There was a tendency to increased risk of asthma among atopic woodworkers compared to atopic non-exposed subjects, with ORs between 3.0 (0.8–11.9) (symptomatic BHR) and 1.3 (0.5–4.2) (work related symptoms). In woodworkers, asthma was associated with atopy, with ORs between 7.4 (2.8–19.7) (symptomatic BHR) and 4.2 (2.4–7.7) (asthma symptoms). Asthma was related to Dust level, most pronounced for symptomatic BHR among atopics, with OR 22.9 (1.0–523.6) for the highest compared to the lowest Dust level. For work related asthma symptoms the association with Dust level was seen only for non-atopics. Conclusions: Wood Dust Exposure was associated with asthma, despite a low Dust level compared to other studies. Atopy was an important effect modifier in the association between asthma and wood Dust Exposure.
Dennis Nowak - One of the best experts on this subject based on the ideXlab platform.
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respirable quartz Dust Exposure and airway obstruction a systematic review and meta analysis
European Respiratory Journal, 2014Co-Authors: Irene Bruske, Elisabeth Thiering, Joachim Heinrich, Katharina M Huster, Dennis NowakAbstract:Objective: Studies on Exposure to respirable quartz Dust at the workplace and the development of chronic obstructive lung disease (COPD) were selected into a systematic review, and meta-analyzed to obtain an overall estimate of FEV1 and FEV1/FVC reduction. Data sources: PubMed and Embase were searched from 1970-2010. In total, 257 cross-sectional and longitudinal studies were identified that reported on inorganic Dust Exposure and had available lung function data. Of the 55 publications which met our inclusion criteria, 11 reported on associations with occupational Exposure to respirable quartz Dust. Methods: The combined average effect estimate of respirable quartz Dust on spirometric parameters was obtained using a random effects model meta-analysis. Between-study heterogeneity was assessed via the I² statistic. Results: Most studies found a significant negative association of FEV1 and FEV1/FVC related to increasing Exposure to crystalline quartz at the workplace. One study found an effect only for smokers, and one did not observe such an effect at all. The meta-analysis of cross-sectional studies showed that the mean ratio FEV1/FVC was reduced and FEV1 of workers exposed to respirable quartz Dust was 4.6% less than predicted compared to workers with no/low Exposure. Both results showed a statistically significant difference. Conclusion: Occupational Exposure to respirable quartz Dust was associated with a statistically significant decrease in FEV1 and FEV1/FVC, revealing airway obstruction consistent with COPD. funded by the German Federal Ministry of Labor and Social Affairs.
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respirable quartz Dust Exposure and airway obstruction a systematic review and meta analysis
Occupational and Environmental Medicine, 2014Co-Authors: Irene Bruske, Elisabeth Thiering, Joachim Heinrich, Katharina M Huster, Dennis NowakAbstract:Studies on Exposure to respirable quartz Dust at the workplace and the development of chronic obstructive pulmonary disease (COPD) were selected into a systematic review and meta-analysed to obtain an overall estimate of forced expiratory volume in 1 s (FEV 1 ) and FEV 1 /forced vital capacity (FVC) reduction. PubMed and Embase were searched from 1970 to 2010. In total, 257 cross-sectional and longitudinal studies were identified that reported on inorganic Dust Exposure and had available lung function data. Of the 55 publications which met our inclusion criteria, 11 reported on associations with occupational Exposure to respirable quartz Dust. The combined average effect estimate of respirable quartz Dust on spirometric parameters was obtained using a random effects model meta-analysis. Between-study heterogeneity was assessed via the I 2 statistic. Most studies found a significant negative association of FEV 1 and FEV 1 /FVC related to increasing Exposure to crystalline quartz at the workplace. One study found an effect only for smokers, and one did not observe such an effect at all. The meta-analysis of cross-sectional studies showed that the mean ratio FEV 1 to FVC was reduced and FEV 1 of workers exposed to respirable quartz Dust was 4.6% less than predicted compared with workers with no/low Exposure. Both results showed a statistically significant difference. Occupational Exposure to respirable quartz Dust was associated with a statistically significant decrease in FEV 1 and FEV 1 /FVC, revealing airway obstruction consistent with COPD.
Baju Widjasena - One of the best experts on this subject based on the ideXlab platform.
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perbedaan paparan debu pada pekerja penggilingan padi pregolan desa jetis kecamatan kaliwungu kabupaten semarang sebelum dan sesudah pemasangan local exhaust ventilation
Jurnal Kesehatan Masyarakat (e-Journal), 2014Co-Authors: Bina Kurniawan, Baju WidjasenaAbstract:The rice milling process gives rise to variety of hazard. Hazard identification in the rice milling in Pregolan Desa Jetis Kecamatan Kaliwungu Kabupaten Semarang shows that there is chemical hazard in the form of grain Dust that is included in organic Dust. Dust is hazard that negatively affect number one in causing occupational disease. Disease arising due to organic Dust, among others, organic Dust toxicity syndrome, farmer lung and asthma. Preliminary research in the rice milling in Pregolan Desa Jetis Kecamatan Kaliwungu Kabupaten Semarang shows that the workers often feel uncomfortable and have difficulty breathing while working because of the grain Dust. Therefore, the control needs to be done to reduce Dust Exposure, namely the installation of local exhaust ventilation. The purpose of this research is to analyze the differences of Dust Exposure to rice milling workers in Pregolan Desa Jetis Kecamatan Kaliwungu Kabupaten Semarang before and after the installation of local exhaust ventilation. This is an experimental research with one group pretest posttest design. The population in this research is measurement results of Dust Exposure to rice milling workers in Pregolan Desa Jetis Kecamatan Kaliwungu Kabupaten Semarang. The sample of this research is each four measurement results of Dust Exposure before and after the installation of local exhaust ventilation. Data analysis is conducted by comparing measurement results of Dust Exposure before and after the installation of local exhaust ventilation. The results showed that Dust Exposure after the installation of local exhaust ventilation dropped amounted to 0,5 mg/m 3 , 0,3 mg/m 3 and 2,0 mg/m 3 . The conclusion is the installation of local exhaust ventilation in rice milling Pregolan Desa Jetis Kecamatan Kaliwungu Kabupaten Semarang can reduce the Dust Exposure
