The Experts below are selected from a list of 228 Experts worldwide ranked by ideXlab platform
Kris R Jatana - One of the best experts on this subject based on the ideXlab platform.
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pediatric cotton tip applicator related Ear Injury treated in united states emergency departments 1990 2010
The Journal of Pediatrics, 2017Co-Authors: Zeenath Ameen, Thiphalak Chounthirath, Gary A Smith, Kris R JatanaAbstract:Objective To evaluate the characteristics of children with cotton-tip applicator (CTA)-related Ear injuries. Study design Data on CTA-related Ear injuries among children presenting to US emergency departments (EDs) from 1990 through 2010 were obtained from the National Electronic Injury Surveillance System. Results Between 1990 and 2010, an estimated 263 338 children aged Conclusion Most CTA-related injuries occurred with children themselves handling CTAs while cleaning their Ears. Foreign body and tympanic membrane perforation were the most common associated diagnoses. Despite warnings against the use of CTAs in the Ear canal and use of CTAs by children, these injuries continued to occur. Additional Injury prevention strategies through further parent/caregiver and child education are warranted.
Daniel I Choo - One of the best experts on this subject based on the ideXlab platform.
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macrophage inflammatory proteins in cytomegalovirus related inner Ear Injury
Otolaryngology-Head and Neck Surgery, 2007Co-Authors: Scott A Schraff, Mark R Schleiss, David Brown, Jareen Meinzenderr, Yeon K Choi, John H Greinwald, Daniel I ChooAbstract:OBJECTIVE: Inner Ear inflammation triggered by CMV infection may play a role in CMV-related auditory pathogenesis. The purpose of the study was to determine if a virally encoded macrophage inflammatory protein played a role in CMV-related hEaring loss. DESIGN: Mutagenesis was performed with deletion of a guinea pig CMV macrophage inflammatory protein. IntracochlEar inoculations were performed on three groups of animals (n = 18). Group 1 received sterile viral media, Group 2 received wild-type CMV virus, and Group 3 received "knockout" (KO) virus with a deleted immunomodulation gene. Baseline and postinoculation ABRs were obtained. ELISA and PCR were performed and temporal bones examined. SUBJECTS: Eighteen guinea pigs. RESULTS: The KO group had significantly better hEaring than the WT group. There were no significant differences between the KO and sham groups. The WT group had significant hEaring loss at all frequencies. Inflammation and fibrosis were noted in the WT temporal bones only. CONCLUSIONS: Virally encoded macrophage inflammatory proteins appEar to play a significant role in CMV-related hEaring loss.
Zeenath Ameen - One of the best experts on this subject based on the ideXlab platform.
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pediatric cotton tip applicator related Ear Injury treated in united states emergency departments 1990 2010
The Journal of Pediatrics, 2017Co-Authors: Zeenath Ameen, Thiphalak Chounthirath, Gary A Smith, Kris R JatanaAbstract:Objective To evaluate the characteristics of children with cotton-tip applicator (CTA)-related Ear injuries. Study design Data on CTA-related Ear injuries among children presenting to US emergency departments (EDs) from 1990 through 2010 were obtained from the National Electronic Injury Surveillance System. Results Between 1990 and 2010, an estimated 263 338 children aged Conclusion Most CTA-related injuries occurred with children themselves handling CTAs while cleaning their Ears. Foreign body and tympanic membrane perforation were the most common associated diagnoses. Despite warnings against the use of CTAs in the Ear canal and use of CTAs by children, these injuries continued to occur. Additional Injury prevention strategies through further parent/caregiver and child education are warranted.
Gary A Smith - One of the best experts on this subject based on the ideXlab platform.
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pediatric cotton tip applicator related Ear Injury treated in united states emergency departments 1990 2010
The Journal of Pediatrics, 2017Co-Authors: Zeenath Ameen, Thiphalak Chounthirath, Gary A Smith, Kris R JatanaAbstract:Objective To evaluate the characteristics of children with cotton-tip applicator (CTA)-related Ear injuries. Study design Data on CTA-related Ear injuries among children presenting to US emergency departments (EDs) from 1990 through 2010 were obtained from the National Electronic Injury Surveillance System. Results Between 1990 and 2010, an estimated 263 338 children aged Conclusion Most CTA-related injuries occurred with children themselves handling CTAs while cleaning their Ears. Foreign body and tympanic membrane perforation were the most common associated diagnoses. Despite warnings against the use of CTAs in the Ear canal and use of CTAs by children, these injuries continued to occur. Additional Injury prevention strategies through further parent/caregiver and child education are warranted.
John H Greinwald - One of the best experts on this subject based on the ideXlab platform.
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macrophage inflammatory proteins in cytomegalovirus related inner Ear Injury
Otolaryngology-Head and Neck Surgery, 2007Co-Authors: Scott A Schraff, Mark R Schleiss, David Brown, Jareen Meinzenderr, Yeon K Choi, John H Greinwald, Daniel I ChooAbstract:OBJECTIVE: Inner Ear inflammation triggered by CMV infection may play a role in CMV-related auditory pathogenesis. The purpose of the study was to determine if a virally encoded macrophage inflammatory protein played a role in CMV-related hEaring loss. DESIGN: Mutagenesis was performed with deletion of a guinea pig CMV macrophage inflammatory protein. IntracochlEar inoculations were performed on three groups of animals (n = 18). Group 1 received sterile viral media, Group 2 received wild-type CMV virus, and Group 3 received "knockout" (KO) virus with a deleted immunomodulation gene. Baseline and postinoculation ABRs were obtained. ELISA and PCR were performed and temporal bones examined. SUBJECTS: Eighteen guinea pigs. RESULTS: The KO group had significantly better hEaring than the WT group. There were no significant differences between the KO and sham groups. The WT group had significant hEaring loss at all frequencies. Inflammation and fibrosis were noted in the WT temporal bones only. CONCLUSIONS: Virally encoded macrophage inflammatory proteins appEar to play a significant role in CMV-related hEaring loss.
