The Experts below are selected from a list of 9000 Experts worldwide ranked by ideXlab platform
Cüneyt Orhan Kara - One of the best experts on this subject based on the ideXlab platform.
-
Does corticosteroid usage in rhinoplasty cause mood changes
Advances in Therapy, 2006Co-Authors: Osman Özdel, Inci Gokalan Kara, Nalan Kalkan Oguzhanoglu, Cüneyt Orhan Kara, Demet Sevinc, Bülent TopuzAbstract:In this study, the psychological effects of single-dose corticosteroids administered to patients who had undergone rhinoplasty were assessed. A total of 30 rhinoplasty patients were included in the study and were randomly assigned to 1 of 2 groups. Preoperatively, patients completed the Bech Rafaelsen Mania Scale and the Beck Depression Inventory. Dexamethasone 10 mg was given intravenously just before surgery to the first group, but no medication was administered to the second group. On the first postoperative day, patients were seen again, and the Bech Rafaelsen Mania Scale and the Beck Depression Inventory were again completed. Periorbital edema and Ecchymosis were graded, and psychological well-being was measured on a standard visual analog scale. All patients and physicians were blinded to treatment until the end of the study. Results show that administration of a single-dose of dexamethasone 10 mg caused neither euphoria nor depression. No significant differences were observed between steroid and control groups in terms of patients’ psychological well-being. With single-dose dexamethasone, periorbital edema was significantly reduced on the first 2 postoperative days, and upper eyelid Ecchymosis was significantly decreased only on the first postoperative day. However, preoperative steroid administration had no influence on Ecchymosis of the lower eyelid. The authors conclude that single-dose dexamethasone 10 mg can be used safely to reduce periorbital edema and Ecchymosis in rhinoplasty patients.
-
does creating a subperiosteal tunnel influence the periorbital edema and Ecchymosis in rhinoplasty
Journal of Oral and Maxillofacial Surgery, 2005Co-Authors: Cüneyt Orhan Kara, Inci Gokalan Kara, Bülent TopuzAbstract:Purpose The study goal was to determine whether creating a subperiosteal tunnel before lateral osteotomy had an effect on postoperative periorbital edema, Ecchymosis, and subconjunctival Ecchymosis. Patients and Methods Eighteen consecutive patients who underwent septorhinoplasty were included in the study. In all patients lateral osteotomies were carried out bilaterally, after creating a subperiosteal tunnel on a randomly chosen side and without creating a subperiosteal tunnel on the other side. The patients were seen on the second postoperative day, and a different surgeon who was unaware of the side with the periosteal tunnel determined the side of the face with more edema and Ecchymosis. Subconjunctival Ecchymosis was evaluated and recorded, as well. Results Creating subperiosteal tunnels before lateral osteotomy statistically increased periorbital Ecchymosis. Although there was no statistically significant difference, creating subperiosteal tunnels also increased development and severity of subconjunctival Ecchymosis and edema. Conclusions We suggest performing lateral osteotomy without creating subperiosteal tunnels.
-
Subconjunctival Ecchymosis due to rhinoplasty.
Rhinology, 2001Co-Authors: Cüneyt Orhan Kara, YaylaliAbstract:Seventy-three patients were included in the study, and informed consent was obtained. Each patient was asked about the history of the major nasal trauma, systemic hypertension and the intake of anti-aggregant drugs. For female patients, no operation was performed during or immediately before the menstrual period. Dexamethasone (10 mg) was given intravenously SUMMARY Orbital complications of rhinoplasty show a wide range from minor complications like periorbital edema and Ecchymosis to severe complications like blindness. Also, subconjunctival Ecchymosis is one of the orbital complications due to rhinoplasty. A prospective study was set out to assess the incidence and progresssion of subconjunctival Ecchymosis and to find out mechanisms of this complication. The incidence of subconjunctival Ecchymosis was found to be 19,1%. Typically it appeared unilaterally or bilaterally over the temporal subconjunctival area in the first two days after the operation. Complete resolution of subconjunctival Ecchymosis took approximately 11 ± 3 days. No other ocular symptoms were found. Subconjunctival Ecchymosis only prolonged the recovery period of the patient from the rhinoplasty.
-
effects of single dose steroid usage on edema Ecchymosis and intraoperative bleeding in rhinoplasty
Plastic and Reconstructive Surgery, 1999Co-Authors: Cüneyt Orhan Kara, Inci GokalanAbstract:To examine the effects of single-dose dexamethasone use on edema, Ecchymosis, and intraoperative bleeding in rhinoplasty, a double-blind, randomized trial with placebo control was planned. A total of 55 consecutive patients were included in the study. The dexamethasone (10 mg) was given intravenously just before surgery (preoperative group, n=18) or at the end of surgery (postoperative group, n=20). In the placebo group, 17 patients received saline preoperatively or postoperatively. Intraoperative blood loss was recorded for each patient. Postoperative scoring of eyelid swelling and Ecchymosis was begun after approximately 24 hours and lasted into postoperative day 9. Only for the first 2 days was the difference between steroid groups (preoperative and postoperative) and the placebo group statistically significant for a decrease in eyelid edema (p < 0.05). A statistically significant difference in upper eyelid Ecchymosis for both preoperative and postoperative steroid groups versus the placebo group also existed in the first 2 days (p < 0.05). Preoperative or postoperative steroid administration had no influence on the Ecchymosis of the lower eyelid. When the results of the preoperative and postoperative steroid groups were compared, no significant difference was detected between the two groups in either edema or Ecchymosis. To determine whether steroid use shortened the recovery period, the days on which edema and Ecchymosis reached a minimum level were compared among the groups; no statistically significant difference was found among them. Using single-dose dexamethasone preoperatively did not alter intraoperative blood loss. Use of single-dose dexamethasone (either preoperatively or postoperatively) in rhinoplasty has a significant effect in decreasing upper and lower eyelid edema and upper eyelid Ecchymosis for the first 2 days when compared with a placebo group. However, the effect of dexamethasone was lost after the first 2 days, and its use did not shorten the recovery period.
Paulo Ricardo Saquete Martinsfilho - One of the best experts on this subject based on the ideXlab platform.
-
preoperative tranexamic acid for treatment of bleeding edema and Ecchymosis in patients undergoing rhinoplasty a systematic review and meta analysis
Archives of Otolaryngology-head & Neck Surgery, 2018Co-Authors: Sara Juliana De Abreu De Vasconcellos, Edmundo Marques Do Nascimentojunior, Marcel Vinicius De Aguiar Menezes, Mario Luis Tavares Mendes, Rafael De Souza Dantas, Paulo Ricardo Saquete MartinsfilhoAbstract:Importance Evidence has emerged on the efficacy of tranexamic acid to control blood loss and postoperative complications after rhinoplasty. Objective To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital Ecchymosis in rhinoplasty. Data Sources and Study Selection For this systematic review of randomized clinical trials, searches were performed in PubMed, Cochrane Central Register of Controlled Trials, Web of Science, SCOPUS, Science Direct, Google Scholar, OpenThesis, and ClinicalTrials.gov from inception to December 23, 2017. Key words includedtranexamic acid,rhinoplasty, andnasal surgical procedures.The following elements were used to define eligibility criteria: (1) population: patients undergoing rhinoplasty surgery; (2) intervention and controls: tranexamic acid vs placebo solution or no-treatment control group; (3) outcomes: intraoperative bleeding, postoperative eyelid edema and periorbital Ecchymosis, and thromboembolic events; and (4) study type: randomized clinical trials. Data Extraction and Synthesis Two reviewers extracted data and assessed study quality according to the Cochrane guidelines for randomized clinical trials. Treatment effects were defined as weighted mean difference (WMD) and 95% CIs. The strength of evidence was analyzed using the Grading of Recommendations Assessment, Development, and Evaluation rating system. Main Outcomes and Measures Intraoperative bleeding, postoperative eyelid edema and periorbital Ecchymosis. To calculate the effect sizes, means and SDs were obtained for each study group and outcome of interest. Results Five studies comprising 276 patients were included in the systematic review: 177 patients (64.1%) were women, and mean age was 26.8 (range, 16-42) years. Four studies comprising 246 patients estimated the amount in intraoperative bleeding as a primary outcome and were included in the meta-analysis. Eyelid edema and Ecchymosis were evaluated as outcomes in 2 studies. Tranexamic acid was associated with reduced bleeding during rhinoplasty was found (WMD, −42.28 mL; 95% CI, −70.36 to −14.21 mL), with differences (P = .01) between oral (WMD, −61.70 mL; 95% CI, −83.02 to −40.39 mL;I2 = 0%) and intravenous (WMD, −23.88 mL; 95% CI, −45.19 to −2.58 mL;I2 = 56%) administration. Eyelid edema and Ecchymosis scores in patients receiving tranexamic acid were significantly lower compared with the control group within the first postoperative week: lower eyelid edema, WMD, −0.76; 95% CI, −1.04 to −0.49 and lower eyelid Ecchymosis, WMD, −0.94; 95% CI, −1.80 to −0.08. No cases of thromboembolic events were reported. Conclusions and Relevance Current available evidence suggests that preoperative administration of tranexamic acid is safe and may reduce intraoperative bleeding as well as postoperative eyelid edema and Ecchymosis in patients undergoing rhinoplasty.
Inci Gokalan - One of the best experts on this subject based on the ideXlab platform.
-
effects of single dose steroid usage on edema Ecchymosis and intraoperative bleeding in rhinoplasty
Plastic and Reconstructive Surgery, 1999Co-Authors: Cüneyt Orhan Kara, Inci GokalanAbstract:To examine the effects of single-dose dexamethasone use on edema, Ecchymosis, and intraoperative bleeding in rhinoplasty, a double-blind, randomized trial with placebo control was planned. A total of 55 consecutive patients were included in the study. The dexamethasone (10 mg) was given intravenously just before surgery (preoperative group, n=18) or at the end of surgery (postoperative group, n=20). In the placebo group, 17 patients received saline preoperatively or postoperatively. Intraoperative blood loss was recorded for each patient. Postoperative scoring of eyelid swelling and Ecchymosis was begun after approximately 24 hours and lasted into postoperative day 9. Only for the first 2 days was the difference between steroid groups (preoperative and postoperative) and the placebo group statistically significant for a decrease in eyelid edema (p < 0.05). A statistically significant difference in upper eyelid Ecchymosis for both preoperative and postoperative steroid groups versus the placebo group also existed in the first 2 days (p < 0.05). Preoperative or postoperative steroid administration had no influence on the Ecchymosis of the lower eyelid. When the results of the preoperative and postoperative steroid groups were compared, no significant difference was detected between the two groups in either edema or Ecchymosis. To determine whether steroid use shortened the recovery period, the days on which edema and Ecchymosis reached a minimum level were compared among the groups; no statistically significant difference was found among them. Using single-dose dexamethasone preoperatively did not alter intraoperative blood loss. Use of single-dose dexamethasone (either preoperatively or postoperatively) in rhinoplasty has a significant effect in decreasing upper and lower eyelid edema and upper eyelid Ecchymosis for the first 2 days when compared with a placebo group. However, the effect of dexamethasone was lost after the first 2 days, and its use did not shorten the recovery period.
Sara Juliana De Abreu De Vasconcellos - One of the best experts on this subject based on the ideXlab platform.
-
preoperative tranexamic acid for treatment of bleeding edema and Ecchymosis in patients undergoing rhinoplasty a systematic review and meta analysis
Archives of Otolaryngology-head & Neck Surgery, 2018Co-Authors: Sara Juliana De Abreu De Vasconcellos, Edmundo Marques Do Nascimentojunior, Marcel Vinicius De Aguiar Menezes, Mario Luis Tavares Mendes, Rafael De Souza Dantas, Paulo Ricardo Saquete MartinsfilhoAbstract:Importance Evidence has emerged on the efficacy of tranexamic acid to control blood loss and postoperative complications after rhinoplasty. Objective To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital Ecchymosis in rhinoplasty. Data Sources and Study Selection For this systematic review of randomized clinical trials, searches were performed in PubMed, Cochrane Central Register of Controlled Trials, Web of Science, SCOPUS, Science Direct, Google Scholar, OpenThesis, and ClinicalTrials.gov from inception to December 23, 2017. Key words includedtranexamic acid,rhinoplasty, andnasal surgical procedures.The following elements were used to define eligibility criteria: (1) population: patients undergoing rhinoplasty surgery; (2) intervention and controls: tranexamic acid vs placebo solution or no-treatment control group; (3) outcomes: intraoperative bleeding, postoperative eyelid edema and periorbital Ecchymosis, and thromboembolic events; and (4) study type: randomized clinical trials. Data Extraction and Synthesis Two reviewers extracted data and assessed study quality according to the Cochrane guidelines for randomized clinical trials. Treatment effects were defined as weighted mean difference (WMD) and 95% CIs. The strength of evidence was analyzed using the Grading of Recommendations Assessment, Development, and Evaluation rating system. Main Outcomes and Measures Intraoperative bleeding, postoperative eyelid edema and periorbital Ecchymosis. To calculate the effect sizes, means and SDs were obtained for each study group and outcome of interest. Results Five studies comprising 276 patients were included in the systematic review: 177 patients (64.1%) were women, and mean age was 26.8 (range, 16-42) years. Four studies comprising 246 patients estimated the amount in intraoperative bleeding as a primary outcome and were included in the meta-analysis. Eyelid edema and Ecchymosis were evaluated as outcomes in 2 studies. Tranexamic acid was associated with reduced bleeding during rhinoplasty was found (WMD, −42.28 mL; 95% CI, −70.36 to −14.21 mL), with differences (P = .01) between oral (WMD, −61.70 mL; 95% CI, −83.02 to −40.39 mL;I2 = 0%) and intravenous (WMD, −23.88 mL; 95% CI, −45.19 to −2.58 mL;I2 = 56%) administration. Eyelid edema and Ecchymosis scores in patients receiving tranexamic acid were significantly lower compared with the control group within the first postoperative week: lower eyelid edema, WMD, −0.76; 95% CI, −1.04 to −0.49 and lower eyelid Ecchymosis, WMD, −0.94; 95% CI, −1.80 to −0.08. No cases of thromboembolic events were reported. Conclusions and Relevance Current available evidence suggests that preoperative administration of tranexamic acid is safe and may reduce intraoperative bleeding as well as postoperative eyelid edema and Ecchymosis in patients undergoing rhinoplasty.
Ellen Mcdonald - One of the best experts on this subject based on the ideXlab platform.
-
comparison of pain and Ecchymosis with low molecular weight heparin vs unfractionated heparin in patients requiring bridging anticoagulation after warfarin interruption a randomized trial
Journal of Thrombosis and Thrombolysis, 2009Co-Authors: Erin Jamula, Karen Woods, Madeleine Verhovsek, James D Douketis, Ellen McdonaldAbstract:Background Subcutaneous (SC) low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) are safe and efficacious for bridging anticoagulation after warfarin interruption. Although LMWH and UFH are self-administered by >90% of patients, factors that may be important to patients such as differences in pain and Ecchymosis have not been explored. Methods We randomized 24 patients to receive SC LMWH or SC UFH twice-daily during the perioperative period. Injection associated pain was recorded using a visual analogue scale and area of Ecchymosis was measured by digital photography of the injection site on the day of the procedure. Results The area of Ecchymosis was 2-fold higher with UFH than LMWH (19.4 cm2 vs. 8.98 cm2; P = 0.33) and pain was similar with both treatments (115 mm vs. 171 mm; P = 0.25), though neither finding attained statistical significance. Conclusions This exploratory study was underpowered to detect differences between the groups. Further studies are needed to reliably compare pain and Ecchymosis in LMWH vs. UFH.