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Joseph A. Caruso - One of the best experts on this subject based on the ideXlab platform.
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Plasma-Based Gas Chromatography Detectors
Gas Chromatography, 2020Co-Authors: Qilin Chan, Joseph A. CarusoAbstract:Hyphenated plasma-based detectors for GC include both mass spectrometry and atomic emission spectrometry, which use plasma as their ionization sources or optical emission sources, respectively. The popular plasma sources are inductively coupled plasma (ICP), microwave-induced plasma (MIP), and glow discharge (GD). The hyphenated techniques of GC with ICP/MIP/GD inherit the merits of high-resolution separation from GC and excellent sensitivity from the atomic detections, which are essential for performing Elemental Speciation of volatile as well as semivolatile analytes. GC-ICPMS and other GC-plasma spectrometries have been commonly used in environmental and biological studies where ultratrace level (part per trillion or lower) detection is required. The emerging need for Elemental Speciation has been driving the development of new interfaces, new sample preparation procedures, and new methods for GC-plasma spectrometry. On the other hand, the newly developed capabilities have expanded advanced studies of Elemental species in a variety of matrices, water, soil, and biological samples.
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Chapter 7 Nebulizer sample introduction for Elemental Speciation
Comprehensive Analytical Chemistry, 2020Co-Authors: Clayton B'hymer, Joseph A. CarusoAbstract:Publisher Summary The function of the nebulizer in inductively coupled plasma–mass spectrometry (ICP–MS) is to convert a liquid sample into an aerosol for introduction into the plasma. Production of an aerosol, which is defined as a finely dispersed liquid mist or spray suspended in a gas, is the easiest method to introduce a liquid sample into either an ICP or a flame. An aerosol facilitates a uniform sample introduction for both a reproducible signal output and the stable operation of the plasma. The pneumatic nebulizer is the most commonly used type of nebulizer. Three main types of liquid breakup are recognized: dropwise, stringwise, and filmwise. The breakup pattern of a liquid is a function of the gas stream velocity. Increasing velocity can change the breakup pattern in the order of dropwise, to stringwise, to filmwise. High performance liquid chromatography (HPLC) is the most commonly used technique for trace element Speciation, especially in conjunction with ICP-MS detection for which it is well suited for eluent introduction. Capillary electrophoresis (CE) is also used for Speciation, having the added capability of separating components based on electrophoretic mobilities.
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C electrophoresis-inductively coupled plasma-mass spectrometry: an attractive complementary technique for Elemental
2020Co-Authors: Sasi S Kannamkumarath, Katarzyna Wrobel, Kazimierz Wrobel, Joseph A. CarusoAbstract:Some basic and practical aspects of interfacing capillary electrophoresis to inductively coupled plasma-mass spectrometry (CE-ICP-MS) are reviewed in this article with emphasis on the use of this hyphenated technique for Elemental Speciation analysis. The principles behind the techniques of both CE and ICP-MS are introduced. The interfacing of CE to ICP-MS is discussed including several devices and nebulizers reported in literature. A brief account of their advantages and limitations is given. The various CE-ICP-MS applications for Elemental Speciation analysis are also reviewed. Some issues concerning the future of CE-ICP-MS for the Elemental Speciation analyses are discussed. 2002 Elsevier Science B.V. All rights reserved.
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Size-exclusion chromatography-inductively coupled plasma mass spectrometry : An important analytical tool for Elemental Speciation in environmental and biological samples
2020Co-Authors: Baki B. M. Sadi, Anne P Vonderheide, J. Sabine Becker, Joseph A. CarusoAbstract:The coupling of size-exclusion chromatography (SEC) to inductively coupled plasma mass spectrometric (ICP-MS) detection has proven to be an exceptional analytical strategy. SEC promotes a size-based separation of macromolecules while ICP-MS yields Elemental profiles. In this review, particular considerations of the interfacing of these two techniques are detailed. Furthermore, applications of this coupled technique are discussed. Specifically, the use of SEC-ICP-MS in the growing area of Elemental Speciation studies is of great importance because mobility, bioavailability and toxicity of the different physico-chemical forms of the elements largely depends on their Elemental distribution in the different size fractions of the macromolecules. Additionally, SEC-ICP-MS has been found to be a great use in the analysis of biological macromolecules, most often proteins, as research efforts extend to the elucidation of reaction mechanisms and evaluation of binding capacities of different elements with biological entities.
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Chapter 9 The use of ICP-MS as a detector for Elemental Speciation studies
Comprehensive Analytical Chemistry, 2020Co-Authors: Kathryn L Ackley, Karen L Sutton, Joseph A. CarusoAbstract:Publisher Summary The inductively coupled plasma–mass spectrometer (ICP–MS) is one of the most widely used detectors for Elemental Speciation studies. ICP–MS is used for the routine determination and quantification of trace elements in aqueous solution, although with slight modifications, these instruments may analyze gaseous samples. Solid samples may also be analyzed by ICP–MS when used in conjunction with solid sampling techniques such as laser ablation (LA) or electrothermal vaporization (ETV). Speciation analyses are most typically performed with liquid sample introduction or gaseous sample introduction. ICP–MS is capable of analyzing samples containing metallic elements as well as metalloids such as arsenic. However, non-metals including the halogens are difficult to analyze because they possess higher ionization potentials than metallic elements, and the argon ICP cannot ionize these elements as efficiently. The ICP–MS possesses several characteristics that make it a very attractive detector for Elemental Speciation studies. For most elements, the detection limits obtained with ICP–MS are significantly lower than those achieved with inductively coupled plasma-atomic emission spectroscopy (ICP–AES), another frequently used detector for Speciation studies.
Julian F. Tyson - One of the best experts on this subject based on the ideXlab platform.
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Atomic spectrometry update: review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2020Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This review covers advances in Elemental Speciation by a range of coupled techniques, including HPLC-ICP-MS, HPLC-HG-AFS and GC-ICP-MS.
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Atomic spectrometry updates. Review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2020Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the sixth Atomic Spectrometry Update (ASU) to focus specifically on advances in Elemental Speciation and covers a period of approximately 12 months from December 2012. This review deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom- containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not specifically deal with fractionation, sometimes termed operationally defined Speciation. As with all ASU reviews 1-5 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, molecular MS techniques are covered where the use is in parallel or series with atomic spectrometry. As with previous years As and Se Speciation continues to dominate current literature. However, research is moving further towards understanding the toxicological and beneficial mechanisms of these two elements. There is also in increase in macromolecular analysis, with a decrease in detection limits for some methodologies, which increases the potential clinical use of the techniques employed. The use of both atomic and molecular spectrometry is well developed in these fields, highlighting the interdisciplinary nature of today's research environment. The trend towards lower cost more rapid analytical methods, often involving non-chromatographic Speciation, also continues apace. This journal is © 2014 the Partner Organisations
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atomic spectrometry update review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2015Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the eighth Atomic Spectrometry Update (ASU) to focus on advances in Elemental Speciation and covers a period of approximately 12 months from December 2014. This ASU review deals with all aspects of the analytical atomic spectrometry Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not cover fractionation, which is sometimes termed operationally defined Speciation. As with all ASU reviews the focus of the research reviewed includes those methods that incorporate atomic spectrometry as the measurement technique. However, because Speciation analysis is inherently focused on the relationship between the metal(loid) atom and the organic moiety it is bound to, or incorporated within, atomic spectrometry alone cannot be the sole analytical approach of interest. For this reason molecular detection techniques are also included where they have provided a complementary approach to Speciation analysis. As in previous years, As and Se Speciation continues to dominate the current literature and there has also been an increase in the number of publications concerning solid state Speciation. This is presumably due to the increase in the number of synchrotron facilities available and a greater awareness of their potential for Speciation studies.
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atomic spectrometry update Elemental Speciation review
Journal of Analytical Atomic Spectrometry, 2013Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the fifth Atomic Spectrometry Update (ASU) to focus specifically on developments in Elemental Speciation and covers a period of approximately 12 months from January 2012. The International Union for Pure and Applied Chemistry (IUPAC) have evaluated Speciation and provided a definition as follows: “Speciation analysis is the analytical activity of identifying and/or measuring the quantities of one or more individual chemical species in a sample; the chemical species are specific forms of an element defined as to isotopic composition, electronic or oxidation state, and/or complex or molecular structure; the Speciation of an element is the distribution of an element amongst defined chemical species in a system”. This review therefore deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. As with all ASU reviews1–5 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, in the spirit of meeting the needs of the subject, material is incorporated that is not strictly “atomic spectrometry”. For the most part, such procedures are those in which some form of molecular MS is used for Speciation measurements, often in parallel with an Elemental detector. As the content of this Update shows, the field is now maturing as evidenced by the extent to which the Speciation of particular elements or technique combinations have been the subject of review articles. However, it is becoming increasingly difficult to ascertain the analytical details of the methodologies applied in Speciation analysis, particularly where the paper is published in an ‘application’ based journal.
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atomic spectrometry update Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2009Co-Authors: Chris F. Harrington, Robert Clough, Steve J. Hill, Helle Rusz Hansen, Spiros A Pergantis, Julian F. TysonAbstract:This is the fourth Atomic Spectrometry Update (ASU) to focus specifically on developments in Elemental Speciation and covers a period of approximately 12 months from January 2011. The International Union for Pure and Applied Chemistry (IUPAC) has evaluated Speciation and provided a definition as follows: “Speciation analysis is the analytical activity of identifying and/or measuring the quantities of one or more individual chemical species in a sample; the chemical species are specific forms of an element defined as to isotopic composition, electronic or oxidation state, and/or complex or molecular structure; the Speciation of an element is the distribution of an element amongst defined chemical species in a system.” This review therefore deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not cover operationally defined ‘Speciation’, which is correctly termed fractionation. As with all ASU reviews1–6 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, in the spirit of meeting the needs of the subject, material is incorporated that is not strictly “atomic spectrometry” but the separation or sample introduction technique used could also be coupled with an atomic spectrometry detector. For the most part, such procedures are those in which some form of molecular MS is used for Speciation measurements. As the content of this Update shows, the field is now maturing as evidenced by the extent to which the Speciation of particular elements or technique combinations have been the subject of review articles. However, it is becoming increasingly difficult to ascertain the analytical details of the methodologies applied in Speciation analysis, particularly where the paper is published in an ‘application’ based journal.
Enzo Lombi - One of the best experts on this subject based on the ideXlab platform.
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critical review perspective Elemental Speciation analysis methods in environmental chemistry moving towards methodological integration
Environmental Chemistry, 2009Co-Authors: Jorg Feldmann, Pascal Salaun, Enzo LombiAbstract:Environmental context. Elemental Speciation defines mobility, accumulation behaviour and toxicity of elements in the environment. Environmental processes are then modelled using species information. Hence, it is important for environmental chemists to rely on unequivocal, precise and accurate analytical data for the identification and quantification of Elemental species. Abstract. We review the application of Speciation analysis used in environmental chemistry studies to gain information about the molecular diversity of elements in various environmental compartments. The review focuses on three major analytical methodologies: electrochemical, X-ray absorption spectroscopy, and methods that couple chromatography with mass spectrometric detection. In particular, the review aims to highlight the advantages and disadvantages of the three methods, and to demonstrate that both the chemistry of the element and the nature of the environmental compartment determine the choice of the preferred analytical technique. We demonstrate that these two factors can lead to technique-dependent shortcomings that contribute to the current gaps in knowledge of Elemental Speciation in the environment. In order to fill those gaps, multi-method approaches are urgently needed. Finally, we present a selection of recent studies that exhibit the potential to use complementary techniques to overcome method-dependent limitations in order to reduce ambiguities and to gain more confidence in the assignment of the molecular structure of elements in environmental samples.
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Critical review perspective: Elemental Speciation analysis methods in environmental chemistry – moving towards methodological integration
Environmental Chemistry, 2009Co-Authors: Jorg Feldmann, Pascal Salaun, Enzo LombiAbstract:Environmental context. Elemental Speciation defines mobility, accumulation behaviour and toxicity of elements in the environment. Environmental processes are then modelled using species information. Hence, it is important for environmental chemists to rely on unequivocal, precise and accurate analytical data for the identification and quantification of Elemental species. Abstract. We review the application of Speciation analysis used in environmental chemistry studies to gain information about the molecular diversity of elements in various environmental compartments. The review focuses on three major analytical methodologies: electrochemical, X-ray absorption spectroscopy, and methods that couple chromatography with mass spectrometric detection. In particular, the review aims to highlight the advantages and disadvantages of the three methods, and to demonstrate that both the chemistry of the element and the nature of the environmental compartment determine the choice of the preferred analytical technique. We demonstrate that these two factors can lead to technique-dependent shortcomings that contribute to the current gaps in knowledge of Elemental Speciation in the environment. In order to fill those gaps, multi-method approaches are urgently needed. Finally, we present a selection of recent studies that exhibit the potential to use complementary techniques to overcome method-dependent limitations in order to reduce ambiguities and to gain more confidence in the assignment of the molecular structure of elements in environmental samples.
Robert Clough - One of the best experts on this subject based on the ideXlab platform.
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Atomic spectrometry update: review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2020Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This review covers advances in Elemental Speciation by a range of coupled techniques, including HPLC-ICP-MS, HPLC-HG-AFS and GC-ICP-MS.
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Atomic spectrometry updates. Review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2020Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the sixth Atomic Spectrometry Update (ASU) to focus specifically on advances in Elemental Speciation and covers a period of approximately 12 months from December 2012. This review deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom- containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not specifically deal with fractionation, sometimes termed operationally defined Speciation. As with all ASU reviews 1-5 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, molecular MS techniques are covered where the use is in parallel or series with atomic spectrometry. As with previous years As and Se Speciation continues to dominate current literature. However, research is moving further towards understanding the toxicological and beneficial mechanisms of these two elements. There is also in increase in macromolecular analysis, with a decrease in detection limits for some methodologies, which increases the potential clinical use of the techniques employed. The use of both atomic and molecular spectrometry is well developed in these fields, highlighting the interdisciplinary nature of today's research environment. The trend towards lower cost more rapid analytical methods, often involving non-chromatographic Speciation, also continues apace. This journal is © 2014 the Partner Organisations
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atomic spectrometry update review of advances in Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2015Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the eighth Atomic Spectrometry Update (ASU) to focus on advances in Elemental Speciation and covers a period of approximately 12 months from December 2014. This ASU review deals with all aspects of the analytical atomic spectrometry Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not cover fractionation, which is sometimes termed operationally defined Speciation. As with all ASU reviews the focus of the research reviewed includes those methods that incorporate atomic spectrometry as the measurement technique. However, because Speciation analysis is inherently focused on the relationship between the metal(loid) atom and the organic moiety it is bound to, or incorporated within, atomic spectrometry alone cannot be the sole analytical approach of interest. For this reason molecular detection techniques are also included where they have provided a complementary approach to Speciation analysis. As in previous years, As and Se Speciation continues to dominate the current literature and there has also been an increase in the number of publications concerning solid state Speciation. This is presumably due to the increase in the number of synchrotron facilities available and a greater awareness of their potential for Speciation studies.
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atomic spectrometry update Elemental Speciation review
Journal of Analytical Atomic Spectrometry, 2013Co-Authors: Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. TysonAbstract:This is the fifth Atomic Spectrometry Update (ASU) to focus specifically on developments in Elemental Speciation and covers a period of approximately 12 months from January 2012. The International Union for Pure and Applied Chemistry (IUPAC) have evaluated Speciation and provided a definition as follows: “Speciation analysis is the analytical activity of identifying and/or measuring the quantities of one or more individual chemical species in a sample; the chemical species are specific forms of an element defined as to isotopic composition, electronic or oxidation state, and/or complex or molecular structure; the Speciation of an element is the distribution of an element amongst defined chemical species in a system”. This review therefore deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. As with all ASU reviews1–5 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, in the spirit of meeting the needs of the subject, material is incorporated that is not strictly “atomic spectrometry”. For the most part, such procedures are those in which some form of molecular MS is used for Speciation measurements, often in parallel with an Elemental detector. As the content of this Update shows, the field is now maturing as evidenced by the extent to which the Speciation of particular elements or technique combinations have been the subject of review articles. However, it is becoming increasingly difficult to ascertain the analytical details of the methodologies applied in Speciation analysis, particularly where the paper is published in an ‘application’ based journal.
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atomic spectrometry update Elemental Speciation
Journal of Analytical Atomic Spectrometry, 2009Co-Authors: Chris F. Harrington, Robert Clough, Steve J. Hill, Helle Rusz Hansen, Spiros A Pergantis, Julian F. TysonAbstract:This is the fourth Atomic Spectrometry Update (ASU) to focus specifically on developments in Elemental Speciation and covers a period of approximately 12 months from January 2011. The International Union for Pure and Applied Chemistry (IUPAC) has evaluated Speciation and provided a definition as follows: “Speciation analysis is the analytical activity of identifying and/or measuring the quantities of one or more individual chemical species in a sample; the chemical species are specific forms of an element defined as to isotopic composition, electronic or oxidation state, and/or complex or molecular structure; the Speciation of an element is the distribution of an element amongst defined chemical species in a system.” This review therefore deals with all aspects of the analytical Speciation methods developed for: the determination of oxidation states; organometallic compounds; coordination compounds; metal and heteroatom-containing biomolecules, including metalloproteins, proteins, peptides and amino acids; and the use of metal-tagging to facilitate detection via atomic spectrometry. The review does not cover operationally defined ‘Speciation’, which is correctly termed fractionation. As with all ASU reviews1–6 the coverage of the topic is confined to those methods that incorporate atomic spectrometry as the measurement technique. However, in the spirit of meeting the needs of the subject, material is incorporated that is not strictly “atomic spectrometry” but the separation or sample introduction technique used could also be coupled with an atomic spectrometry detector. For the most part, such procedures are those in which some form of molecular MS is used for Speciation measurements. As the content of this Update shows, the field is now maturing as evidenced by the extent to which the Speciation of particular elements or technique combinations have been the subject of review articles. However, it is becoming increasingly difficult to ascertain the analytical details of the methodologies applied in Speciation analysis, particularly where the paper is published in an ‘application’ based journal.
Gunda Koellensperger - One of the best experts on this subject based on the ideXlab platform.
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It is time for a special issue dedicated to Elemental Speciation analysis
Journal of Analytical Atomic Spectrometry, 2020Co-Authors: Heidi Goenaga-infante, Gunda KoellenspergerAbstract:Guest Editors, Heidi Goenaga-Infante and Gunda Koellensperger, introduce the 2016 Speciation themed issue.
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monitoring the production process of selenized yeast by Elemental Speciation analysis
Metallomics, 2012Co-Authors: Evelyn Rampler, Stephan Rose, Dominik Wieder, Anja Ganner, Ilse Dohnal, Thomas Dalik, Stephan Hann, Gunda KoellenspergerAbstract:Elemental Speciation analysis was implemented as an essential tool set addressing optimum fermentation conditions for the production of selenized yeast feed supplements. Accordingly, the study addressed intracellular levels of (1) total selenium and sulfur, (2) seleno methionine (SeMet), (3) cysteine (Cys) and methionine (Met) and (4) selenite and selenate. Dedicated sample preparation- and LC-ICP-MS methods were implemented and validated using the reference material Selm-1. Excellent repeatability precisions <10% (n = 4 biological replicates) could be obtained for all parameters. The study comprised fermentation monitoring over 72 hours (6 different time points) for a Saccharomyces cerevisiae strain under different selenite feed conditions. It was observed that for this strain an increase in the selenium concentration in the fermentation feed by 50% did not result in enhanced selenium accumulation. Fermentation monitoring of three different Saccharomyces cerevisiae strains under the same conditions showed strain specific selenium uptake after 72 hours. The strain with the lowest cell viability of 60% showed the lowest SeMet content. After 47 h of fermentation, all strains reached a critical point, at which seleno methionine accounted for approximately 100% of the total selenium and cell viability started to decrease. This could be explained by sulfur limitation and/or excess of the seleno methionine storage capacity. Strains showing cell viability of approx. 90% after 72 hours of fermentation revealed SeMet concentrations up to 3000 μg g−1. In the final product, an apparent threshold level for Met/SeMet of approx. 1 was observed for all strains.
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Monitoring the production process of selenized yeast by Elemental Speciation analysis.
Metallomics, 2012Co-Authors: Evelyn Rampler, Stephan Rose, Dominik Wieder, Anja Ganner, Ilse Dohnal, Thomas Dalik, Stephan Hann, Gunda KoellenspergerAbstract:Elemental Speciation analysis was implemented as an essential tool set addressing optimum fermentation conditions for the production of selenized yeast feed supplements. Accordingly, the study addressed intracellular levels of (1) total selenium and sulfur, (2) seleno methionine (SeMet), (3) cysteine (Cys) and methionine (Met) and (4) selenite and selenate. Dedicated sample preparation- and LC-ICP-MS methods were implemented and validated using the reference material Selm-1. Excellent repeatability precisions
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environmental application of Elemental Speciation analysis based on liquid or gas chromatography hyphenated to inductively coupled plasma mass spectrometry a review
Analytica Chimica Acta, 2010Co-Authors: Maximilian Popp, Stephan Hann, Gunda KoellenspergerAbstract:In recent years the number of environmental applications of Elemental Speciation analysis using inductively coupled plasma mass spectrometry (ICP-MS) as detector has increased significantly. The analytical characteristics, such as extremely low detection limits (LOD) for almost all elements, the wide linear range, the possibility for multi-Elemental analysis and the possibility to apply isotope dilution mass spectrometry (IDMS) make ICP-MS an attractive tool for Elemental Speciation analysis. Two methodological approaches, i.e. the combination of ICP-MS with high performance liquid chromatography (HPLC) and gas chromatography (GC), dominate the field. Besides the investigation of metals and metalloids and their species (e.g. Sn, Hg, As), representing “classic” elements in environmental science, more recently other elements (e.g. P, S, Br, I) amenable to ICP-MS determination were addressed. In addition, the introduction of isotope dilution analysis and the development of isotopically labeled species-specific standards have contributed to the success of ICP-MS in the field. The aim of this review is to summarize these developments and to highlight recent trends in the environmental application of ICP-MS coupled to GC and HPLC.