The Experts below are selected from a list of 312 Experts worldwide ranked by ideXlab platform
Peter G.a. Hompes - One of the best experts on this subject based on the ideXlab platform.
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Stadardization of catheter load speed during Embryo Transfer; comparison of manual and pump-regulated Embryo Transfer
Reproductive Biomedicine Online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, O.w. Visser, L.h. Langeveld, Martijn W Heymans, Roel Schats, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Standardization of catheter load speed during Embryo Transfer: comparison of manual and pump-regulated Embryo Transfer
Reproductive biomedicine online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, L.h. Langeveld, Martijn W Heymans, Roel Schats, Otto Visser, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Ultrasonographic-guided Embryo Transfer does not enhance pregnancy rates compared with Embryo Transfer based on previous uterine length measurement.
Fertility and sterility, 2006Co-Authors: M.j. Lambers, Roel Schats, Erbil Dogan, Hanna Kostelijk, Jan Willem Lens, Peter G.a. HompesAbstract:Objective To compare pregnancy rates (PRs) after ultrasound-guided Embryo Transfer and Embryo Transfer based on ultrasonographic length measurement. Design Prospective intervention group combined with retrospective control group. Setting University fertility clinic. Patient(s) Patients undergoing IVF and intracytoplasmic sperm injection. Intervention(s) Transabdominal ultrasonographic guidance at Embryo Transfer. Main Outcome Measure(s) Pregnancy and implantation rates. Result(s) In 367 ultrasound-guided Embryo Transfers clinical PR, ongoing PR, and implantation rate were 35.1%, 31.1%, and 24.3%, respectively. In 363 Embryo Transfers based on previous ultrasonographic length measurement, the rates were 33.9%, 29.5%, and 24.2%, respectively. There were no statistical significant differences between the groups. Conclusion(s) Ultrasonographic guidance does not show any benefit in terms of PR and implantation rate compared to previous ultrasonographic length measurement, an other precise and atraumatic Transfer technique.
William B. Schoolcraft - One of the best experts on this subject based on the ideXlab platform.
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Ultrasound-Guided Embryo Transfer
Biennial Review of Infertility, 2011Co-Authors: R.l. Gustofson, William B. SchoolcraftAbstract:The complexity of in vitro fertilization is culminated in the Embryo Transfer. Failure to achieve a successful Transfer can negate the effort of the entire process. Any method to facilitate an easier Transfer with higher pregnancy rates is considered a necessary step. Ultrasound-guided Embryo Transfer has become integrated in most IVF centers because of its ease of use, reassurance of proper Embryo placement, and improved pregnancy rates.
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Embryo Transfer: techniques and variables affecting success
Fertility and sterility, 2001Co-Authors: William B. Schoolcraft, Eric S. Surrey, David K. GardnerAbstract:Abstract Objective: To review the literature on the variables affecting Embryo Transfer success or failure and to define technical factors associated with optimal outcome. Design: Literature review. Results: Avoidance of blood, mucus, bacterial contamination, excessive uterine contractions, and trauma to the endometrium is associated with optimal pregnancy and implantation rates after transcervical Embryo Transfer. A trial Transfer, ultrasonographic guidance, and use of "soft" catheters appear to facilitate successful Embryo Transfer. Conclusion: An understanding of the variables associated with Embryo Transfer success together with adherence to techniques shown to facilitate atraumatic Embryo Transfer will enhance the efficiency of IVF by maximizing Embryo implantation.
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Embryo Transfer and Luteal Phase Support
ART and the Human Blastocyst, 2001Co-Authors: William B. SchoolcraftAbstract:The main variables affecting pregnancy and implantation rates are uterine receptivity, Embryo quality, and Transfer efficiency. Much less effort has historically been placed on assessing or maximizing Embryo Transfer procedures compared with the other aspects of in vitro fertilization. Embryo Transfer is usually performed blindly with no attempt to document the variables that might adversely impact pregnancy rates. Physicians too frequently underestimate the importance of the Embryo Transfer technique and are often unwilling to modify their own personal habits or catheter choices.
M.j. Lambers - One of the best experts on this subject based on the ideXlab platform.
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Stadardization of catheter load speed during Embryo Transfer; comparison of manual and pump-regulated Embryo Transfer
Reproductive Biomedicine Online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, O.w. Visser, L.h. Langeveld, Martijn W Heymans, Roel Schats, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Standardization of catheter load speed during Embryo Transfer: comparison of manual and pump-regulated Embryo Transfer
Reproductive biomedicine online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, L.h. Langeveld, Martijn W Heymans, Roel Schats, Otto Visser, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Ultrasonographic-guided Embryo Transfer does not enhance pregnancy rates compared with Embryo Transfer based on previous uterine length measurement.
Fertility and sterility, 2006Co-Authors: M.j. Lambers, Roel Schats, Erbil Dogan, Hanna Kostelijk, Jan Willem Lens, Peter G.a. HompesAbstract:Objective To compare pregnancy rates (PRs) after ultrasound-guided Embryo Transfer and Embryo Transfer based on ultrasonographic length measurement. Design Prospective intervention group combined with retrospective control group. Setting University fertility clinic. Patient(s) Patients undergoing IVF and intracytoplasmic sperm injection. Intervention(s) Transabdominal ultrasonographic guidance at Embryo Transfer. Main Outcome Measure(s) Pregnancy and implantation rates. Result(s) In 367 ultrasound-guided Embryo Transfers clinical PR, ongoing PR, and implantation rate were 35.1%, 31.1%, and 24.3%, respectively. In 363 Embryo Transfers based on previous ultrasonographic length measurement, the rates were 33.9%, 29.5%, and 24.2%, respectively. There were no statistical significant differences between the groups. Conclusion(s) Ultrasonographic guidance does not show any benefit in terms of PR and implantation rate compared to previous ultrasonographic length measurement, an other precise and atraumatic Transfer technique.
Mohamed Abd El Aziz Mousta - One of the best experts on this subject based on the ideXlab platform.
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Elective single Embryo Transfer versus double Embryo Transfer in assisted reproduction
Reproductive biomedicine online, 2008Co-Authors: Mohamed Khaled Moustafa, Sheded Ashour Sheded, Mohamed Abd El Aziz MoustaAbstract:High numbers of Embryos Transferred during assisted reproduction have become implicated as the cause of higher than normal twinning and multiple gestation rates following this form of therapy. However, reducing the number to a single Embryo Transferred has been shown to carry unfavourable results in the first cycle, but with similar cumulative live birth rates. This study tested the theory by performing a randomized controlled trial of elective single Embryo Transfer (SET) versus double Embryo Transfer (DET) in young women, and follow them up for 1 year to determine the result of cryo-Embryo Transfer cycles in the two cohorts. The results showed that the probability of a live birth was not significantly different between the two groups, but with a higher rate of twins in the DET group. In addition, during the 1-year follow-up period, the live birth, clinical pregnancy and multiple pregnancy rates were also similar, and in line with the results of the randomized trial. In conclusion, the results of this prospective randomized trial and 1-year follow-up show that in young women, elective SET should be the first line of choice. Even so, these results should be confirmed by larger randomized studies.
Roel Schats - One of the best experts on this subject based on the ideXlab platform.
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Stadardization of catheter load speed during Embryo Transfer; comparison of manual and pump-regulated Embryo Transfer
Reproductive Biomedicine Online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, O.w. Visser, L.h. Langeveld, Martijn W Heymans, Roel Schats, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Standardization of catheter load speed during Embryo Transfer: comparison of manual and pump-regulated Embryo Transfer
Reproductive biomedicine online, 2011Co-Authors: Els Groeneveld, C.g. Vergouw, Bram De Leeuw, M.j. Lambers, L.h. Langeveld, Martijn W Heymans, Roel Schats, Otto Visser, Peter G.a. HompesAbstract:Abstract The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the conventional manual Embryo-Transfer technique it is not possible to predict the final position of the air bubbles. This position mainly depends on the catheter load speed at Transfer (injection speed), a parameter that remains uncontrollable with the conventional technique even after standardization of the protocol. Therefore, the development of an automated device that generates a standardized injection speed is desirable. This study aimed to examine the variation in injection speeds in manual Embryo Transfer and pump-regulated Embryo Transfer (PRET). Seven laboratory technicians were asked to perform simulated Transfers using the conventional Embryo-Transfer technique. Their injection speeds were compared with that of a PRET device. The results indicate that in manually performed Transfers, even after standardization of the protocol, there is still a large variation in injection speed, while a PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether these experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates. The position of Transfer air bubbles after Embryo Transfer is related to the pregnancy rate. With the currently used Embryo-Transfer technique, in which Embryos are Transferred manually with a syringe, we are not able to predict the final position of the air bubbles. This position depends on the injection speed of the syringe, which remains uncontrollable in Embryo Transfers that are performed manually even after standardization of the protocol. Therefore we developed an automated device that generates a reliable and reproducible injection speed, a pump-regulated Embryo Transfer (PRET) device. This study aimed to examine the variation in injection speeds in Transfers performed manually and with the PRET device. Our results indicate that in manually performed Transfers, even after standardization by protocol, there is still a large variation in injection speed and that the PRET device generates a reliable and reproducible injection speed and therefore brings new possibilities for further standardization of the Embryo-Transfer procedure. Future research should reveal whether our experiments mimic real clinical circumstances and if a standardized injection speed results in more exact positioning of the Transferred Embryos and therefore higher pregnancy rates.
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Ultrasonographic-guided Embryo Transfer does not enhance pregnancy rates compared with Embryo Transfer based on previous uterine length measurement.
Fertility and sterility, 2006Co-Authors: M.j. Lambers, Roel Schats, Erbil Dogan, Hanna Kostelijk, Jan Willem Lens, Peter G.a. HompesAbstract:Objective To compare pregnancy rates (PRs) after ultrasound-guided Embryo Transfer and Embryo Transfer based on ultrasonographic length measurement. Design Prospective intervention group combined with retrospective control group. Setting University fertility clinic. Patient(s) Patients undergoing IVF and intracytoplasmic sperm injection. Intervention(s) Transabdominal ultrasonographic guidance at Embryo Transfer. Main Outcome Measure(s) Pregnancy and implantation rates. Result(s) In 367 ultrasound-guided Embryo Transfers clinical PR, ongoing PR, and implantation rate were 35.1%, 31.1%, and 24.3%, respectively. In 363 Embryo Transfers based on previous ultrasonographic length measurement, the rates were 33.9%, 29.5%, and 24.2%, respectively. There were no statistical significant differences between the groups. Conclusion(s) Ultrasonographic guidance does not show any benefit in terms of PR and implantation rate compared to previous ultrasonographic length measurement, an other precise and atraumatic Transfer technique.