The Experts below are selected from a list of 4155 Experts worldwide ranked by ideXlab platform
Xuefang Liang - One of the best experts on this subject based on the ideXlab platform.
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toxicogenomic applications of chinese rare minnow gobiocypris rarus in aquatic toxicology
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2016Co-Authors: Xuefang LiangAbstract:Abstract Rare minnow (Gobiocypris rarus), a Chinese native species, are an excellent Emerging model organism for aquatic toxicity testing and chemical safety assessment. “Big data” omics approaches (i.e., genomics, proteomics, and metabolomics) to inform mechanistic toxicology are now applied to studies in rare minnows to better understand toxicity and molecular pathways perturbed by chemicals. This review highlights recent applications of toxicogenomics to study changes in the gene and protein expression profiles in rare minnows in response to chemicals. Here we briefly describe studies that utilized cDNA microarrays in characterization of the cellular effects of rare minnows in single and mixed chemical exposures. Then we compare gel-based proteomics studies in liver of rare minnows following treatment with endocrine disrupting chemicals including 17β-estradiol, 17α-methyltestosterone, pentachlorophenol, and perfluorooctanoic acid. A total of 90 proteins identified in these studies were functionally annotated and categorized. These responsive proteins have roles in biological processes that include metabolism (37.8%), response to oxidation/chemicals (16.7%), signal transduction (11.1%), transport (10%), cytoskeleton (6.7%) and others (17.8%). In addition, recent investigations of endocrine disrupting effects and neurotoxicity of benzotriazole, an Emerging Contaminant, are summarized. The objective is to continue to enrich genome and protein databases for this species and to integrate molecular datasets to consider temporal effects and complex regulation at the level of the genome and proteome.
Jiang Xu - One of the best experts on this subject based on the ideXlab platform.
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progress in the biological and chemical treatment technologies for Emerging Contaminant removal from wastewater a critical review
Journal of Hazardous Materials, 2017Co-Authors: Mohammad Boshir Ahmed, John L Zhou, Nikolaos S Thomaidis, Jiang XuAbstract:This review focuses on the removal of Emerging Contaminants (ECs) by biological, chemical and hybrid technologies in effluents from wastewater treatment plants (WWTPs). Results showed that endocrine disruption chemicals (EDCs) were better removed by membrane bioreactor (MBR), activated sludge and aeration processes among different biological processes. Surfactants, EDCs and personal care products (PCPs) can be well removed by activated sludge process. Pesticides and pharmaceuticals showed good removal efficiencies by biological activated carbon. Microalgae treatment processes can remove almost all types of ECs to some extent. Other biological processes were found less effective in ECs removal from wastewater. Chemical oxidation processes such as ozonation/H2O2, UV photolysis/H2O2 and photo-Fenton processes can successfully remove up to 100% of pesticides, beta blockers and pharmaceuticals, while EDCs can be better removed by ozonation and UV photocatalysis. Fenton process was found less effective in the removal of any types of ECs. A hybrid system based on ozonation followed by biological activated carbon was found highly efficient in the removal of pesticides, beta blockers and pharmaceuticals. A hybrid ozonation-ultrasound system can remove up to 100% of many pharmaceuticals. Future research directions to enhance the removal of ECs have been elaborated.
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uptake accumulation and elimination of polystyrene microspheres in tadpoles of xenopus tropicalis
Chemosphere, 2016Co-Authors: Lingling Hu, Lei Su, Jingli Mu, Jiang XuAbstract:Microplastic is an Emerging Contaminant affecting freshwater and marine ecosystem across the globe. In the present study, the filter feeding tadpoles of Xenopus tropicalis were exposed to polystyrene microspheres (1 and 10 μm) for 48 h. Microspheres were observed in gills and digestive tract of tadpoles within 1 h after exposure as well as in feces 6 h after exposure. The accumulation of microspheres in the tadpoles were concentration dependent (Univariate ANOVA, p 0.05). After the exposed tadpoles were transferred to clean water, the number of microspheres in the tadpoles decreased dramatically after 1 d and continued to decrease gradually afterwards. The absorbed polystyrene particles in unfed tadpoles was significantly higher than those in the fed tadpoles at 12 and 24 h after exposure. After transfer to clean water, the fed tadpoles showed a significant decrease in the amount of absorbed polystyrene particles, while the unfed tadpoles showed no significant change in the amount of absorbed polystyrene particles. Our results suggested that microspheres were likely to be ingested and egested relatively fast by tadpoles. Our results indicated that aquatic vertebrate organisms might ingest more microplastics if the abundance of microplastics continues to increase while the available food becomes less.
Weihua Cui - One of the best experts on this subject based on the ideXlab platform.
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degradation of 1 4 dioxane by hydroxyl radicals produced from clay minerals
Journal of Hazardous Materials, 2017Co-Authors: Qiang Zeng, Hailiang Dong, Xi Wang, Weihua CuiAbstract:Abstract 1,4-Dioxane is causing a general concern as an Emerging Contaminant in groundwater environment. Traditional remediation methods can be either inefficient or costly. In this study, we present a cost effective method for possible in situ remediation of 1,4-dioxane. Hydroxyl radicals ( OH) produced from oxygenation of structural Fe(II) in ferruginous clay minerals significantly degraded high concentrations of 1,4-dioxane (up to 400 μmol/L) within 120 h under circumneutral pH and dark condition. The amount of 1,4-dioxane degradation was positively correlated with the amount of OH. The major degradation product of 1,4-dioxane was formic acid. Different clay mineral types, initial Fe(II) concentration, and buffer composition all affected OH production and 1,4-dioxane degradation efficiency. Nontronite, an iron-rich smectite, was a reusable and effective material for sustainable production of OH and 1,4-dioxane degradation, through regeneration of Fe(II) either biologically or chemically. The non-selectivity and strong oxidative power of OH make it a promising agent for remediating various kinds of organic Contaminants in aqueous environment.
Nicole C Deziel - One of the best experts on this subject based on the ideXlab platform.
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1 4 dioxane as an Emerging water Contaminant state of the science and evaluation of research needs
Science of The Total Environment, 2019Co-Authors: Krystal Godri J Pollitt, Jaehong Kim, Jordan Peccia, Menachem Elimelech, Yawei Zhang, Georgia Charkoftaki, Brenna Hodges, Ines Zucker, Huang Huang, Nicole C DezielAbstract:1,4-Dioxane has historically been used to stabilize chlorinated solvents and more recently has been found as a Contaminant of numerous consumer and food products. Once discharged into the environment, its physical and chemical characteristics facilitate migration in groundwater, resulting in widespread contamination of drinking water supplies. Over one-fifth of U.S. public drinking water supplies contain detectable levels of 1,4-dioxane. Remediation efforts using common adsorption and membrane filtration techniques have been ineffective, highlighting the need for alternative removal approaches. While the data evaluating human exposure and health effects are limited, animal studies have shown chronic exposure to cause carcinogenic responses in the liver across multiple species and routes of exposure. Based on this experimental evidence, the U.S. Environmental Protection Agency has listed 1,4-dioxane as a high priority chemical and classified it as a probable human carcinogen. Despite these health concerns, there are no federal or state maximum Contaminant levels for 1,4-dioxane. Effective public health policy for this Emerging Contaminant requires additional information about human health effects, chemical interactions, environmental fate, analytical detection, and treatment technologies. This review highlights the current state of knowledge, key uncertainties, and data needs for future research on 1,4-dioxane.
Baowei Chen - One of the best experts on this subject based on the ideXlab platform.
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the role of class i integrons in the dissemination of sulfonamide resistance genes in the pearl river and pearl river estuary south china
Journal of Hazardous Materials, 2015Co-Authors: Baowei Chen, Ximei Liang, Xiaoping Huang, Xiangdong LiAbstract:Abstract Antibiotic resistance genes (ARGs), as a newly Emerging Contaminant, are unique because they are disseminated through horizontal gene transfer in the environment. In the present study, a class 1 integron gene ( int 1) and various ARGs ( sul 1, sul 2, sul 3, qnr S, and erm B) were measured in water and sediment samples from the Pearl River (PR) to the Pearl River Estuary (PRE), where there is a distinct gradient in anthropogenic impact. The int 1, sul 1, and sul 2 genes were detected in all samples, and their concentrations exhibited a clear trend of decline consistent with anthropogenic impact. Both the int 1 and sul genes had dynamically migrated between water and sediments. The relative abundance of the int 1 gene normalized to the 16S rRNA gene correlated significantly with the total concentrations of antibiotics in water and sediments. Good correlations were also observed between the abundance of int 1 and each type of sul gene in the samples. However, the sul 1 gene showed a much stronger relationship with int 1 in different seasons, probably due to the presence of sul 1 in the conserved region of class 1 integron. Our results strongly support that integrons play an important role in the dissemination of ARGs in human-impacted aquatic environments.