The Experts below are selected from a list of 276 Experts worldwide ranked by ideXlab platform

Oguzhan Ekizoglu - One of the best experts on this subject based on the ideXlab platform.

  • Forensic age estimation via magnetic resonance imaging of knee in the Turkish population: use of T1-TSE sequence
    International Journal of Legal Medicine, 2020
    Co-Authors: Oguzhan Ekizoglu, Ali Er, Mustafa Bozdag, Can Doruk Basa, Ismail Eralp Kacmaz, Negahnaz Moghaddam, Silke Grabherr
    Abstract:

    The evaluation of epiphyseal areas by magnetic resonance imaging (MRI) for forensic age estimation is an important supportive diagnostic method to prevent repeated radiation exposure without a valid medical reason. There are still not enough individuals being analyzed with MRI for age estimation. The aim of this study was to investigate the utility of T1-weighted turbo spin echo (T1-TSE) MRI sequences in determining the degree of ossification of the distal femoral and proximal tibial Epiphyses in a Turkish population. In this study, images from 649 patients (335 males and 314 females) aged 10–30 years were retrospectively evaluated with sagittal T1-weighted turbo spin echo (T1-TSE) MRI sequences of the knee. Proximal tibial and distal femoral epiphysis were scored by two different observers twice using the combined staging system described by Schmeling and Kellinghaus. Spearman’s rank correlation analysis indicated a significant positive relationship between age and ossification stages of the distal femoral and proximal tibial Epiphyses ( p  

  • forensic age estimation via 3 t magnetic resonance imaging of ossification of the proximal tibial and distal femoral Epiphyses use of a t2 weighted fast spin echo technique
    Forensic Science International, 2016
    Co-Authors: Oguzhan Ekizoglu, Elif Hocaoglu, Ercan Inci, Ismail Ozgur Can, Sema Aksoy, Cemal Kazimoglu
    Abstract:

    Radiation exposure during forensic age estimation is associated with ethical implications. It is important to prevent repetitive radiation exposure when conducting advanced ultrasonography (USG) and magnetic resonance imaging (MRI). The purpose of this study was to investigate the utility of 3.0-T MRI in determining the degree of ossification of the distal femoral and proximal tibial Epiphyses in a group of Turkish population. We retrospectively evaluated coronal T2-weighted and turbo spin-echo sequences taken upon MRI of 503 patients (305 males, 198 females; age 10-30 years) using a five-stage method. Intra- and interobserver variations were very low. (Intraobserver reliability was κ=0.919 for the distal femoral epiphysis and κ=0.961 for the proximal tibial epiphysis, and interobserver reliability was κ=0.836 for the distal femoral epiphysis and κ=0.885 for the proximal tibial epiphysis.) Spearman's rank correlation analysis indicated a significant positive relationship between age and the extent of ossification of the distal femoral and proximal tibial Epiphyses (p<0.001). Comparison of male and female data revealed significant between-gender differences in the ages at first attainment of stages 2, 3, and 4 ossifications of the distal femoral epiphysis and stage 1 and 4 ossifications of the proximal tibial epiphysis (p<0.05). The earliest ages at which ossification of stages 3, 4, and 5 was evident in the distal femoral epiphysis were 14, 17, and 22 years in males and 13, 16, and 21 years in females, respectively. Proximal tibial epiphysis of stages 3, 4, and 5 ossification was first noted at ages 14, 17, and 18 years in males and 13, 15, and 16 years in females, respectively. MRI of the distal femoral and proximal tibial Epiphyses is an alternative, noninvasive, and reliable technique to estimate age.

Richard L. Hutchison - One of the best experts on this subject based on the ideXlab platform.

  • Radiographic indicators of a shared epiphysis in radial polydactyly
    HAND, 2014
    Co-Authors: Michael H. Johnson, Roshan T. Melvani, Neil N. Patel, Christine J. Cheng, Richard L. Hutchison
    Abstract:

    Background Thumb Epiphyses cannot be visualized on radiographs in infants with radial polydactyly, making it difficult to classify by Wassel type. The purpose of this study was to identify radiographic features that distinguish a separate epiphysis from a shared epiphysis. This may assist in operative planning and establishing prognosis. Methods The charts of 34 radial polydactyly patients treated with surgical reconstruction from 2008 through 2012 were retrospectively reviewed. Measurements of the most proximal bones involved in the duplication, including length, width at shaft, width at base, distance between radial and ulnar thumb, and angle between radial and ulnar thumb, were taken from PA radiographs of the thumb by four blinded individuals. The interclass correlation coefficient was calculated to determine inter-observer reliability. Operative notes were reviewed to distinguish between shared and separate Epiphyses. Several indices were created from these measurements. Results Radiographic measurements showed high inter-observer reliability. There were statistically significant differences between patients with separate and shared Epiphyses for indices for the width shaft index, interspace distance, the angle × interspace distance, and the angle × interspace index. Conclusion Radiographic differences exist between children with separate and shared Epiphyses. In patients with shared Epiphyses, the radial thumb tends to be smaller, closer to the ulnar thumb, and less divergent. Threshold values were identified for predicting the status of the epiphysis based on the angle × interspace distance and the angle × interspace index. These values may be used to help determine in advance of surgery if a shared epiphysis exists.

  • Radiographic indicators of a shared epiphysis in radial polydactyly
    Hand, 2014
    Co-Authors: Michael H. Johnson, Roshan T. Melvani, Neil N. Patel, Christine J. Cheng, Richard L. Hutchison
    Abstract:

    Background Thumb Epiphyses cannot be visualized on radiographs in infants with radial polydactyly, making it difficult to classify by Wassel type. The purpose of this study was to identify radiographic features that distinguish a separate epiphysis from a shared epiphysis. This may assist in operative planning and establishing prognosis.

Randall T. Loder - One of the best experts on this subject based on the ideXlab platform.

  • demographic predictors of severity of stable slipped capital femoral Epiphyses
    Journal of Bone and Joint Surgery American Volume, 2006
    Co-Authors: Randall T. Loder, Trevor Starnes, Greg Dikos, David D Aronsson
    Abstract:

    Background: The outcome of stable slipped capital femoral epiphysis is directly related to the severity of the slip. If it is assumed that the slip will be less severe if it is diagnosed early, then early diagnosis should improve the prognosis. It was our purpose to determine demographic predictors of the severity of a slipped capital femoral epiphysis. Methods: A retrospective study of 243 children with a total of 328 stable slipped capital femoral Epiphyses was performed. Gender, race, age, and symptom duration were noted. Slip severity was classified as mild ( 50°). Statistical analyses included bivariate, multivariate, linear correlation, and logistic regression techniques. Results: There were 159 boys and eighty-four girls; 149 children had unilateral and ninety-four had bilateral slipped capital femoral epiphysis. Of the bilateral slips, forty-two were simultaneous and fifty-two were sequential. The mean age (and standard deviation) was 12.6 ± 1.8 years, the mean duration of the symptoms was 5.2 ± 7.4 months, and the mean slip angle was 29° ± 20°. There were 199 mild, sixty-eight moderate, and forty-five severe slips. The mean duration of symptoms was 3.5 ± 5.0 months for the mild slips, 7.7 ± 9.0 months for the moderate slips, and 8.8 ± 10.6 months for the severe slips (p < 0.0001). Older children had more severe slips: the average age was 12.3 ± 1.8 years for the children with a mild slip, 13.0 ± 1.6 years for those with a moderate slip, and 13.8 ± 1.8 years for those with a severe slip (p < 0.0001). Multivariate analyses demonstrated that, among the factors studied, only the age of the patient and the duration of the symptoms were associated with the slip severity. Symptom duration and patient age were used as predictors of slip severity in a logistic regression analysis, with ≥30° and <30° used as the categories for slip severity, older than 12.5 years old compared with 12.5 years old or younger used as the categories for age, and more than 2.0 months compared with 2.0 months or less used as the categories for symptom duration. This model predicted the probability of a slip with confidence (p < 0.0001). The odds ratios (with 95% confidence intervals) for age and symptom duration were 2.0 (1.15 to 3.53) and 4.1 (2.34 to 7.12), respectively. Thus, a child with a stable slipped capital femoral epiphysis is 2.0 times more likely to have a moderate or severe slip if he or she is older than 12.5 years of age at the time of the diagnosis and 4.1 times more likely to have a moderate or severe slip if the duration of symptoms was longer than two months. Conclusions: The only two known significant predictors of the severity of a slipped capital femoral epiphysis are age at diagnosis and symptom duration. For any individual child, slip severity and symptom duration are unique; in a large population, there is a general correlation between slip severity and increases in patient age and increases in the duration of symptoms. Level of Evidence: Prognostic Level II. See Instructions to Authors for a complete description of levels of evidence.

  • Slipped capital femoral epiphysis.
    American Family Physician, 1998
    Co-Authors: Randall T. Loder
    Abstract:

    Slipped capital femoral epiphysis occurs during the adolescent growth spurt and is most frequent in obese children. Up to 40 percent of cases are bilateral. Recent classification methods emphasize epiphyseal stability rather than symptom duration. Most cases of slipped capital femoral Epiphyses are stable and have a good prognosis if diagnosed early. Unstable slipped capital femoral epiphysis has a much poorer prognosis because of the high risk of avascular necrosis. Early radiographic clues are the metaphyseal blanch sign and Klein's line. Once diagnosed, treatment should begin immediately. The most widely accepted treatment for a stable slipped capital femoral epiphysis is in situ fixation with a single central screw. The treatment for an unstable slipped capital femoral epiphysis is much more controversial. Corrective osteotomy is usually reserved for treatment of severe deformities after the patient has stopped growing.

Diego Jaramillo - One of the best experts on this subject based on the ideXlab platform.

  • Normal maturation of the distal femoral epiphyseal cartilage: age-related changes at MR imaging.
    Radiology, 2000
    Co-Authors: Laura J. Varich, Tal Laor, Diego Jaramillo
    Abstract:

    PURPOSE: To determine how signal intensity in the cartilaginous distal part of the femoral epiphysis varies with (a) age, (b) sex, and (c) distribution to the medial or lateral condyle on magnetic resonance (MR) images. MATERIALS AND METHODS: Sixty-six sagittal T2-weighted or inversion-recovery MR images of the distal femoral epiphysis in children aged 2 months to 5 years 5 months were evaluated. Epiphyses were categorized into five types on the basis of progressive signal intensity changes within the epiphyseal cartilage along the weight-bearing region and posterior condyles. Epiphyseal type was compared with age, sex, and distribution of signal intensity changes within the condyle. RESULTS: In early infancy, epiphyseal cartilage was homogeneous. During the 2nd year, signal intensity along the weight-bearing region decreased. With further advancing age, signal intensity in the posterior femoral condyles increased and became progressively more focal. The increase in epiphyseal grade correlated with age fo...

  • normal gadolinium enhanced mr images of the developing appendicular skeleton part i cartilaginous epiphysis and physis
    American Journal of Roentgenology, 1997
    Co-Authors: Carol E Barnewolt, F Shapiro, Diego Jaramillo
    Abstract:

    We have used gadolinium-enhanced MR imaging to define the expected normal appearance of the developing cartilaginous Epiphyses and physes in neonates, infants, and children and to define the changes with maturity in epiphyseal vascular pattern.We analyzed gadolinium-enhanced MR images of 80 normal Epiphyses in 48 neonates, infants, and children who were 1 month to 15.5 years old. We studied the differences in enhancement ratios for the Epiphyses and physes and the epiphyseal vascular pattern at various development stages. We correlated the MR imaging findings with histologic and injection studies of immature Epiphyses.Gadolinium enhancement allowed differentiation between physeal and epiphyseal cartilage and revealed epiphyseal vascular canals. Enhancement proved to be greater in the physeal than in the epiphyseal cartilage (p < .001). In the unossified epiphysis, the vascular canals were mainly parallel. After the development of the secondary ossification center, these canals came to have a radial patter...

Silke Grabherr - One of the best experts on this subject based on the ideXlab platform.

  • Forensic age estimation via magnetic resonance imaging of knee in the Turkish population: use of T1-TSE sequence
    International Journal of Legal Medicine, 2020
    Co-Authors: Oguzhan Ekizoglu, Ali Er, Mustafa Bozdag, Can Doruk Basa, Ismail Eralp Kacmaz, Negahnaz Moghaddam, Silke Grabherr
    Abstract:

    The evaluation of epiphyseal areas by magnetic resonance imaging (MRI) for forensic age estimation is an important supportive diagnostic method to prevent repeated radiation exposure without a valid medical reason. There are still not enough individuals being analyzed with MRI for age estimation. The aim of this study was to investigate the utility of T1-weighted turbo spin echo (T1-TSE) MRI sequences in determining the degree of ossification of the distal femoral and proximal tibial Epiphyses in a Turkish population. In this study, images from 649 patients (335 males and 314 females) aged 10–30 years were retrospectively evaluated with sagittal T1-weighted turbo spin echo (T1-TSE) MRI sequences of the knee. Proximal tibial and distal femoral epiphysis were scored by two different observers twice using the combined staging system described by Schmeling and Kellinghaus. Spearman’s rank correlation analysis indicated a significant positive relationship between age and ossification stages of the distal femoral and proximal tibial Epiphyses ( p