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Bofeng Zhu - One of the best experts on this subject based on the ideXlab platform.

  • genetic polymorphism analysis of mitochondrial dna from chinese xinjiang kazak Ethnic Group by a novel mitochondrial dna genotyping panel
    Molecular Biology Reports, 2019
    Co-Authors: Tong Xie, Yuxin Guo, Feng Chen, Bofeng Zhu
    Abstract:

    Genetic polymorphism analysis of 60 mitochondrial DNA (mtDNA) loci in Chinese Xinjiang Kazak Group was conducted in this study. Blood samples from 141 unrelated healthy volunteers were randomly collected from Chinese Kazak Ethnic Group in Ili, Xinjiang Uygur Autonomous region. Among these mtDNA loci, single nucleotide transition was the most commonly observed variant (87.93%). A total of 25 haploGroups and 79 haplotypes were found in Kazak Group, and HaploGroup D4 was the most common haploGroup (21.28%). Among the entire 79 haplotypes, 53 of them were observed for only once, 14 for twice. The haplotype diversity was 0.978 ± 0.005, and the nucleotide diversity was 0.17449. The detection of (CA)n and 9-bp deletion polymorphisms could improve the discrimination power of the mtDNA genetic marker. Moreover, Xinjiang Kazak Group was compared with other previously reported Groups to infer its genetic background. The present results revealed that Xinjiang Kazak Ethnic Group was genetically closer related to Xinjiang Uygur, Xinjiang Uzbek and Xinjiang Han populations. Meanwhile, our results also indicated the potential closer genetic relationships among Xinjiang Kazak Group with Altaian Kazak as well as Xinjiang Xibe Group. In conclusion, this novel mtDNA panel could be effectively utilized for forensic applications. Additionally, to further reveal the genetic background of Chinese Kazak Group, more relevant populations and genetic markers should be incorporated in our future study.

  • genetic polymorphism analysis of 15 str loci in chinese hui Ethnic Group residing in qinghai province of china
    Molecular Biology Reports, 2011
    Co-Authors: Chunmei Shen, Hongdan Wang, Bofeng Zhu, Yajun Deng, Jingfeng Huang, Haixia Qin, Bo Zhang, Shuanliang Fan
    Abstract:

    In the present study, we investigated the diversity distributions of allelic frequencies of 15 short tandem repeats (STRs) loci in a sample of Chinese Hui Ethnic Group in the Ningxia Hui Autonomous Region. The allelic frequencies of the 15 STR loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) were obtained from 2975 unrelated healthy Hui individuals. The STR genotyping data of all the samples were generated by DNA extraction, multiple amplification, GeneScan and genotype analysis. The genetic distances among different populations were calculated by using Nei’s method and a phylogenetic tree was constructed based on the allelic frequencies of the same 15 STR loci using the neighbor-joining method. A total of 185 alleles were observed in the Hui population, with the corresponding allelic frequencies ranging from 0.0002 to 0.5322. Chi-Square tests showed that all STR loci were in Hardy–Weinberg equilibrium. The forensic statistical parameters of all the loci showed high values. The population data in this study were compared with the previously published population data from other Ethnics or areas. The Hui population showed significant differences from the Minnan Han, Uigur, Ewenki, Yi, Tibetan, Maonan and Malay Ethnic minority Groups in some loci, and from the South Morocco population and the Moroccan population in all the loci. Our results are valuable for human individual identification and paternity testing in the Chinese Hui population and are expected to enrich the genetic information resources of Chinese populations.

Quentin J Clemens - One of the best experts on this subject based on the ideXlab platform.

  • the prevalence of lower urinary tract symptoms luts and overactive bladder oab by racial Ethnic Group and age results from oab poll
    Obstetrical & Gynecological Survey, 2013
    Co-Authors: Karin S Coyne, Chris C Sexton, Jill A Bell, Christine L Thompson, Roger R Dmochowski, Tamara Bavendam, Chiehi Chen, Quentin J Clemens
    Abstract:

    AbstractUrinary incontinence (UI) and overactive bladder (OAB) are common lower urinary tract symptoms (LUTSs) in both men and women. Several studies have investigated the impact of racial/Ethnic Group on LUTSs, UI, and OAB. Although rates of LUTSs appear to be similar across racial/Ethnic Groups, U

  • the prevalence of lower urinary tract symptoms luts and overactive bladder oab by racial Ethnic Group and age results from oab poll
    Neurourology and Urodynamics, 2013
    Co-Authors: Karin S Coyne, Chris C Sexton, Jill A Bell, Christine L Thompson, Roger R Dmochowski, Tamara Bavendam, Chiehi Chen, Quentin J Clemens
    Abstract:

    Aims To estimate the prevalence of LUTS and OAB in a large, Ethnically diverse US study. Methods This cross-sectional, population-representative survey was conducted via the Internet in the US among 10,000 men and women aged 18–70 (2,000 African-Americans [AA], 2,000 Hispanics, 6,000 whites). The LUTS tool assessed how often participants experienced LUTS during the past 4 weeks on a five-point Likert scale. OAB was defined by the presence of urinary urgency ≥ “sometimes” or ≥ “often,” and/or the presence of urgency urinary incontinence (UUI). Descriptive statistics were used to evaluate Group differences. Logistic regression analyses were conducted to examine the impact of racial/Ethnic Group on OAB. Results Response rate, 56.7%. Prevalent LUTS included terminal dribble and nocturia across gender, post-micturition leaking (men), and stress incontinence (women). Prevalence of OAB ≥ “sometimes” and ≥ “often” were 17% and 8% in men and 30% and 20% in women—with significantly higher rates among AA men and women. A similar trend was found for UUI among men (AA, 10%; Hispanic and whites, 6%), while AA and white women had higher prevalence of UUI (19%) as compared to Hispanic women (16%). In logistic regression analyses, AA and Hispanic men and women were significantly more likely than whites to have OAB despite having lower prevalence of self-reported comorbid conditions and risk factors. Conclusions LUTS and OAB are highly prevalent in both men and women and increase with advancing age. Further, racial/Ethnic Group is a robust predictor of OAB in men and women. Neurourol. Urodynam. 32: 230–237, 2013. © 2012 Wiley Periodicals, Inc.

Karin S Coyne - One of the best experts on this subject based on the ideXlab platform.

  • the prevalence of lower urinary tract symptoms luts and overactive bladder oab by racial Ethnic Group and age results from oab poll
    Obstetrical & Gynecological Survey, 2013
    Co-Authors: Karin S Coyne, Chris C Sexton, Jill A Bell, Christine L Thompson, Roger R Dmochowski, Tamara Bavendam, Chiehi Chen, Quentin J Clemens
    Abstract:

    AbstractUrinary incontinence (UI) and overactive bladder (OAB) are common lower urinary tract symptoms (LUTSs) in both men and women. Several studies have investigated the impact of racial/Ethnic Group on LUTSs, UI, and OAB. Although rates of LUTSs appear to be similar across racial/Ethnic Groups, U

  • the prevalence of lower urinary tract symptoms luts and overactive bladder oab by racial Ethnic Group and age results from oab poll
    Neurourology and Urodynamics, 2013
    Co-Authors: Karin S Coyne, Chris C Sexton, Jill A Bell, Christine L Thompson, Roger R Dmochowski, Tamara Bavendam, Chiehi Chen, Quentin J Clemens
    Abstract:

    Aims To estimate the prevalence of LUTS and OAB in a large, Ethnically diverse US study. Methods This cross-sectional, population-representative survey was conducted via the Internet in the US among 10,000 men and women aged 18–70 (2,000 African-Americans [AA], 2,000 Hispanics, 6,000 whites). The LUTS tool assessed how often participants experienced LUTS during the past 4 weeks on a five-point Likert scale. OAB was defined by the presence of urinary urgency ≥ “sometimes” or ≥ “often,” and/or the presence of urgency urinary incontinence (UUI). Descriptive statistics were used to evaluate Group differences. Logistic regression analyses were conducted to examine the impact of racial/Ethnic Group on OAB. Results Response rate, 56.7%. Prevalent LUTS included terminal dribble and nocturia across gender, post-micturition leaking (men), and stress incontinence (women). Prevalence of OAB ≥ “sometimes” and ≥ “often” were 17% and 8% in men and 30% and 20% in women—with significantly higher rates among AA men and women. A similar trend was found for UUI among men (AA, 10%; Hispanic and whites, 6%), while AA and white women had higher prevalence of UUI (19%) as compared to Hispanic women (16%). In logistic regression analyses, AA and Hispanic men and women were significantly more likely than whites to have OAB despite having lower prevalence of self-reported comorbid conditions and risk factors. Conclusions LUTS and OAB are highly prevalent in both men and women and increase with advancing age. Further, racial/Ethnic Group is a robust predictor of OAB in men and women. Neurourol. Urodynam. 32: 230–237, 2013. © 2012 Wiley Periodicals, Inc.

Iyanrick John - One of the best experts on this subject based on the ideXlab platform.

  • Ethnic Group socioeconomic status as an indicator of community level disadvantage a study of overweight obesity in asian american adolescents
    Social Science & Medicine, 2017
    Co-Authors: Won Kim Cook, Winston Tseng, Iyanrick John
    Abstract:

    Asian American children and adolescents are an under-investigated subpopulation in obesity research. Informed by a wide socioeconomic diversity among Asian American Ethnic Groups, this study explored Ethnic-Group socioeconomic status (SES) as an indicator of community-level disadvantage that may influence overweight/obesity in Asian American adolescents. We hypothesized that Ethnic-Group SES was inversely associated with overweight/obesity in Asian American adolescents. Multiple logistic regression models were fitted using a sample of 1525 Asian American adolescents ages 12–17 from pooled 2007–2012 California Health Interview Survey (CHIS) data. Age, gender, nativity, individual-level SES (income and education), and two lifestyle variables (fast food consumption and physical activity) were controlled for. We found that adolescents in high- or middle-level SES Ethnic Groups were far less likely to be overweight/obese than those in low-SES Ethnic Groups. Further, these relationships were more pronounced for foreign-born adolescents but not significant for U.S.-born adolescents. Ethnic-Group SES may be a meaningful indicator of community-level socioeconomic disparities that influence the health of Asian Americans and, potentially, other populations with high proportions of immigrants of diverse socioeconomic and Ethnic backgrounds.

  • Ethnic Group socioeconomic status as an indicator of community level disadvantage a study of overweight obesity in asian american adolescents
    Social Science & Medicine, 2017
    Co-Authors: Won Kim Cook, Winston Tseng, Iyanrick John, Christina C Tam, Camillia K Lui
    Abstract:

    Asian American children and adolescents are an under-investigated subpopulation in obesity research. Informed by a wide socioeconomic diversity among Asian American Ethnic Groups, this study explored Ethnic-Group socioeconomic status (SES) as an indicator of community-level disadvantage that may influence overweight/obesity in Asian American adolescents. We hypothesized that Ethnic-Group SES was inversely associated with overweight/obesity in Asian American adolescents. Multiple logistic regression models were fitted using a sample of 1525 Asian American adolescents ages 12-17 from pooled 2007-2012 California Health Interview Survey (CHIS) data. Age, gender, nativity, individual-level SES (income and education), and two lifestyle variables (fast food consumption and physical activity) were controlled for. We found that adolescents in high- or middle-level SES Ethnic Groups were far less likely to be overweight/obese than those in low-SES Ethnic Groups. Further, these relationships were more pronounced for foreign-born adolescents but not significant for U.S.-born adolescents. Ethnic-Group SES may be a meaningful indicator of community-level socioeconomic disparities that influence the health of Asian Americans and, potentially, other populations with high proportions of immigrants of diverse socioeconomic and Ethnic backgrounds.

Won Kim Cook - One of the best experts on this subject based on the ideXlab platform.

  • Ethnic Group socioeconomic status as an indicator of community level disadvantage a study of overweight obesity in asian american adolescents
    Social Science & Medicine, 2017
    Co-Authors: Won Kim Cook, Winston Tseng, Iyanrick John
    Abstract:

    Asian American children and adolescents are an under-investigated subpopulation in obesity research. Informed by a wide socioeconomic diversity among Asian American Ethnic Groups, this study explored Ethnic-Group socioeconomic status (SES) as an indicator of community-level disadvantage that may influence overweight/obesity in Asian American adolescents. We hypothesized that Ethnic-Group SES was inversely associated with overweight/obesity in Asian American adolescents. Multiple logistic regression models were fitted using a sample of 1525 Asian American adolescents ages 12–17 from pooled 2007–2012 California Health Interview Survey (CHIS) data. Age, gender, nativity, individual-level SES (income and education), and two lifestyle variables (fast food consumption and physical activity) were controlled for. We found that adolescents in high- or middle-level SES Ethnic Groups were far less likely to be overweight/obese than those in low-SES Ethnic Groups. Further, these relationships were more pronounced for foreign-born adolescents but not significant for U.S.-born adolescents. Ethnic-Group SES may be a meaningful indicator of community-level socioeconomic disparities that influence the health of Asian Americans and, potentially, other populations with high proportions of immigrants of diverse socioeconomic and Ethnic backgrounds.

  • Ethnic Group socioeconomic status as an indicator of community level disadvantage a study of overweight obesity in asian american adolescents
    Social Science & Medicine, 2017
    Co-Authors: Won Kim Cook, Winston Tseng, Iyanrick John, Christina C Tam, Camillia K Lui
    Abstract:

    Asian American children and adolescents are an under-investigated subpopulation in obesity research. Informed by a wide socioeconomic diversity among Asian American Ethnic Groups, this study explored Ethnic-Group socioeconomic status (SES) as an indicator of community-level disadvantage that may influence overweight/obesity in Asian American adolescents. We hypothesized that Ethnic-Group SES was inversely associated with overweight/obesity in Asian American adolescents. Multiple logistic regression models were fitted using a sample of 1525 Asian American adolescents ages 12-17 from pooled 2007-2012 California Health Interview Survey (CHIS) data. Age, gender, nativity, individual-level SES (income and education), and two lifestyle variables (fast food consumption and physical activity) were controlled for. We found that adolescents in high- or middle-level SES Ethnic Groups were far less likely to be overweight/obese than those in low-SES Ethnic Groups. Further, these relationships were more pronounced for foreign-born adolescents but not significant for U.S.-born adolescents. Ethnic-Group SES may be a meaningful indicator of community-level socioeconomic disparities that influence the health of Asian Americans and, potentially, other populations with high proportions of immigrants of diverse socioeconomic and Ethnic backgrounds.