The Experts below are selected from a list of 1665 Experts worldwide ranked by ideXlab platform
Chingjen Wang - One of the best experts on this subject based on the ideXlab platform.
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ESWT (Extracorporeal Shockwave Therapy) for osteoarthritis of the knee
2020Co-Authors: Chingjen WangAbstract:Hypothesis: ESWT (Extracorporeal Shockwave Therapy) is shown to have chondroprotective effects in the initiation of osteoarthritis changes of the rat knee. It is hypothesized that the effects of ESWT may be similar in human knees. Objectives: To evaluate the the effects and safety of ESWT in early osteoarthritis of human knees.
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Extracorporeal Shockwave Therapy for treatment of keloid scars.
Wound Repair and Regeneration, 2018Co-Authors: Chingjen Wang, Jai-hong Cheng, Wen-yi Chou, Yur-ren KuoAbstract:The purpose of this investigation was to study the effectiveness of Extracorporeal Shockwave Therapy (ESWT) for the treatment of keloid scars, and compared the results with intralesional steroid injection. Thirty-nine patients were randomly divided into 22 in ESWT group and 17 in steroid group. The ESWT group received 3 ESWT treatments in 6 weeks. The steroid group received three intra-lesional triamcinolone injections in 6 weeks. The evaluations included gross morphology, functional outcome, local blood flow perfusion, biopsy for histopathological examination, and immunohistochemical analysis. Both groups showed significant improvements in appearance with less discoloration, flattening and softer consistency, and more elasticity of the lesions. There is a significant reduction in keloid height after treatment in both groups, and significant differences are noticed between two groups after treatment. The volume of keloid was decreased after treatment but there is no statistically significant difference between two groups. Both groups showed comparable functional scores, POSAS patient, and observer scales. The blood flow perfusion rates were statistically not significant between two groups before and after treatments. Histopathological findings revealed no significant difference in cell count, cell activity, and cell concentration between two groups. After ESWT, the significant decreases in collagen type I, type III, and Masson Trichrome stain were observed as compared with steroid group. However, very little changes were noticed in angiogenesis, inflammatory cytokines, proliferating and regeneration, and apoptosis, with no statistical significance noticed between two groups before and after treatment. This study revealed that ESWT showed comparable functional outcome and POSAS patient and observer scales as compared with steroid injection for keloid scars. Treatment of keloid scars with ESWT resulted in significant decreases in collagen fibers and increases in MMP-13 enzyme.
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Prognostic factors for the outcome of Extracorporeal Shockwave Therapy for calcific tendinitis of the shoulder
Journal of Bone and Joint Surgery-british Volume, 2017Co-Authors: Wen-yi Chou, Chingjen Wang, Yj Yang, Kk SiuAbstract:AimsWe conducted a study to identify factors that are prognostic of the outcome of Extracorporeal Shockwave Therapy (ESWT) for calcific tendinitis of the shoulder.Patients and MethodsSince 1998, patients with symptomatic calcific tendinitis of the rotator cuff have been treated with ESWT using an electrohydraulic mode Shockwave device. One year after ESWT, patients were grouped according to the level of resorption of calcification.ResultsOf 241 symptomatic shoulders, complete resorption (CR) of calcification occurred in 134 (CR group). The remaining 107 shoulders had incomplete resorption (ICR) (ICR group). Gartner type I calcification was most common (64.5%) in the ICR group. The mean duration of symptoms before ESWT was significantly longer in the ICR group. Overall, 81% of the CR group and 23.4% of the ICR group were symptom free. There was a strong relationship between subsidence of symptoms and remission of calcification. Poor prognosis was significantly related to Gartner type I calcification, calci...
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Changes of articular cartilage and subchondral bone after Extracorporeal Shockwave Therapy in osteoarthritis of the knee.
International Journal of Medical Sciences, 2017Co-Authors: Chingjen Wang, Jai-hong Cheng, Wen-yi Chou, Shan-ling Hsu, Jen-hung Chen, Chien-yiu HuangAbstract:We assessed the pathological changes of articular cartilage and subchondral bone on different locations of the knee after Extracorporeal Shockwave Therapy (ESWT) in early osteoarthritis (OA). Rat knees under OA model by anterior cruciate ligament transaction (ACLT) and medial meniscectomy (MM) to induce OA changes. Among ESWT groups, ESWT were applied to medial (M) femur (F) and tibia (T) condyles was better than medial tibia condyle, medial femur condyle as well as medial and lateral (L) tibia condyles in gross osteoarthritic areas (p T(M+L) > F(M) in OA rat knees.
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Dosage effects of Extracorporeal Shockwave Therapy in early hip necrosis.
International Journal of Surgery, 2016Co-Authors: Chingjen Wang, Chung-cheng Huang, Hon-kan Yip, Ya-ju YangAbstract:Abstract Background This study investigated the effects of different dosages of Extracorporeal Shockwave Therapy (ESWT) in early osteonecrosis of the femoral head (ONFH). Materials and methods Thirty-three patients (42 hips) were randomly divided into three groups. Group A (10 patients with 16 hips) received 2000 impulses of ESWT at 24 Kv to the affected hip. Group B (11 patients with 14 hips) and Group C (12 patients with 12 hips) received 4000 and 6000 impulses of ESWT respectively. The evaluations included clinical assessment, radiographs, dynamic contrast-enhanced MRI for microcirculation (K trans ) and plasma volume (Vp), and blood tests for biomarker analysis (NO3, VEGF, BMP-2, osteocalcin, TNF-α, IL-6, substance P, CGRP, DKK-1 and IGF). Results Significant differences of pain and Harris hip scores were noticed between Group A and C in 6 months after ESWT (all P 0.05). The post-treatment K trans and Vp in the peri-necrotic areas of Group B and C were significantly greater than pre-treatment data (both P Conclusions High dosage ESWT is more effective in early stage ONFH. The systemic beneficial effects of ESWT may ultimately enhance angiogenesis with improvement of microcirculation of the peri-necrotic areas, that in turn, can improve subchondral bone remodeling and prevent femoral head collapse.
Heinz Lohrer - One of the best experts on this subject based on the ideXlab platform.
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Radial Extracorporeal Shockwave Therapy for the treatment of finger tenosynovitis (trigger digit).
Open access journal of sports medicine, 2016Co-Authors: Nikos Malliaropoulos, Rosanna Jury, Debasish Pyne, Nat Padhiar, Jennifer Turner, Vasileios Korakakis, Maria Meke, Heinz LohrerAbstract:INTRODUCTION Stenosing tenosynovitis that is characterized by the inability to flex the digit smoothly, usually leads to prolonged rehabilitation or surgery. STUDY DESIGN This case series is a retrospective cohort study. PURPOSE The aim of this case series was to evaluate the effectiveness of radial Extracorporeal Shockwave Therapy (rESWT) for the treatment of stenosing tenosynovitis of the digital flexor tendon (trigger digit). METHODS A retrospective analysis of 44 patients (49 fingers) treated with an individually adapted rESWT protocol was conducted. Trigger digit pain and function were evaluated at baseline and 1-, 3-, and 12-months posttreatment. Recurrence and pretreatment symptom duration were analyzed. RESULTS Significant reductions in pain scores and functional improvement were found between baseline and all follow-up assessments (P
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radial Extracorporeal Shockwave Therapy for the treatment of finger tenosynovitis trigger digit
Open access journal of sports medicine, 2016Co-Authors: Nikos Malliaropoulos, Rosanna Jury, Debasish Pyne, Nat Padhiar, Jennifer Turner, Vasileios Korakakis, Maria Meke, Heinz LohrerAbstract:INTRODUCTION Stenosing tenosynovitis that is characterized by the inability to flex the digit smoothly, usually leads to prolonged rehabilitation or surgery. STUDY DESIGN This case series is a retrospective cohort study. PURPOSE The aim of this case series was to evaluate the effectiveness of radial Extracorporeal Shockwave Therapy (rESWT) for the treatment of stenosing tenosynovitis of the digital flexor tendon (trigger digit). METHODS A retrospective analysis of 44 patients (49 fingers) treated with an individually adapted rESWT protocol was conducted. Trigger digit pain and function were evaluated at baseline and 1-, 3-, and 12-months posttreatment. Recurrence and pretreatment symptom duration were analyzed. RESULTS Significant reductions in pain scores and functional improvement were found between baseline and all follow-up assessments (P<0.001). Pretreatment symptom duration was significantly correlated with the number of rESWT sessions required (r=0.776, P<0.001) and 1-year posttreatment pain score (r=0.335, P=0.019). CONCLUSION This study provides initial evidence that rESWT is an effective treatment for trigger digit, but randomised controlled trials are required to provide further evidence of this effect.
Chifai Ng - One of the best experts on this subject based on the ideXlab platform.
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Extracorporeal Shockwave Therapy in the treatment of erectile dysfunction a prospective randomized double blinded placebo controlled study
International Journal of Urology, 2014Co-Authors: Eddie Sy Chan, Chifai NgAbstract:Objectives To investigate the role of low-intensity Extracorporeal Shockwave Therapy in the treatment of erectile dysfunction. Methods This was a double-blinded, single-center, prospective, randomized, placebo-controlled trial. After a 2-week phosphodiesterase type 5 inhibitor washout period, patients were assessed with Sexual Health Inventory for Men, International Index of Erectile Function-ED domain scores and Erection Hardness Score. Randomization into either the low-intensity Extracorporeal Shockwave Therapy group or the sham group took place. After the 9-week treatment period, patients were followed up 4 weeks later. Follow-up assessment was in the form of International Index of Erectile Function-ED domain score and Erection Hardness Score. Results A total of 70 patients were recruited into the study, 58 patients completed the study. A total of 28 patients were randomized into the sham Therapy arm, and 30 patients were randomized into the low-intensity Extracorporeal Shockwave Therapy arm. There was no significant difference between these two groups in baseline International Index of Erectile Function-ED domain score and Erection Hardness Score. The mean International Index of Erectile Function-ED domain score of the low-intensity Extracorporeal Shockwave Therapy arm and sham arm in week 13 were 17.8 ± 4.8 and 15.8 ± 6.1, respectively (P = 0.156). The mean Erection Hardness Scores in week 13 were 2.7 ± 0.5 and 2.4 ± 0.9, respectively (P = 0.163). When patients were stratified into different baseline Sexual Health Inventory for Men subgroups, the pre-intervention and post-intervention difference in low-intensity Extracorporeal Shockwave Therapy was found to be significant in the subgroup with severe erectile dysfunction (low-intensity Extracorporeal Shockwave Therapy International Index of Erectile Function-ED domain improvement: 10.1 ± 4.1 vs sham Therapy International Index of Erectile Function-ED domain improvement: 3.2 ± 3.3; P = 0.003). Conclusion The present trial shows the tolerability and clinical efficacy of low-intensity Extracorporeal Shockwave Therapy in a subgroup of patients with erectile dysfunction.
Shih Wei Huang - One of the best experts on this subject based on the ideXlab platform.
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Clinical efficacy of Extracorporeal Shockwave Therapy for knee osteoarthritis: a systematic review and meta-regression of randomized controlled trials.
Clinical Rehabilitation, 2019Co-Authors: Chun De Liao, Jau-yih Tsauo, Tsan Hon Liou, Hung Chou Chen, Shih Wei HuangAbstract:Objective:This study determined the clinical efficacy of Extracorporeal Shockwave Therapy and the predictors of its efficacy for knee osteoarthritis.Data Sources:Electronic databases and search eng...
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Supplementary_file_1 – Supplemental material for Clinical efficacy of Extracorporeal Shockwave Therapy for knee osteoarthritis: a systematic review and meta-regression of randomized controlled trials
2019Co-Authors: Chun-de Liao, Jau-yih Tsauo, Tsan Hon Liou, Hung Chou Chen, Shih Wei HuangAbstract:Supplemental material, Supplementary_file_1 for Clinical efficacy of Extracorporeal Shockwave Therapy for knee osteoarthritis: a systematic review and meta-regression of randomized controlled trials by Chun-De Liao, Jau-Yih Tsauo, Tsan-Hon Liou, Hung-Chou Chen and Shih-Wei Huang in Clinical Rehabilitation
Bryan Chung - One of the best experts on this subject based on the ideXlab platform.
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Extracorporeal Shockwave Therapy: a review.
Sports Medicine, 2012Co-Authors: Bryan Chung, J. Preston WileyAbstract:Extracorporeal Shockwave Therapy (ESWT) has been in use for the treatment of tendinopathies since the early 1990s. The exact mechanism by which ESWT relieves tendon-associated pain is not known; however, there is an increasing body of literature that suggests that it can be an effective Therapy for patients who have had repeated nonsurgical treatment failures. The highest strength of evidence is shown in randomised controlled trials, of which there are a small number. Reported results for tendinopathies of the shoulder, elbow and heel have shown consistent positive results in favour of ESWT over placebo ESWT in individuals who have failed conservative Therapy. These studies provide strong evidence for ESWT as an effective Therapy for the treatment of chronic treatment-resistant tendinopathies. There is still much debate over several issues surrounding ESWT that have not been adequately addressed by the literature: high- versus low-energy ESWT, Shockwave dosage and number of sessions required for a therapeutic effect. Further research is needed to ascertain the most beneficial protocol for patient care.
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Extracorporeal Shockwave Therapy
Sports Medicine, 2002Co-Authors: Bryan Chung, J. Preston WileyAbstract:Extracorporeal Shockwave Therapy (ESWT) has been in use for the treatment of tendinopathies since the early 1990s. The exact mechanism by which ESWT relieves tendon-associated pain is not known; however, there is an increasing body of literature that suggests that it can be an effective Therapy for patients who have had repeated nonsurgical treatment failures. The highest strength of evidence is shown in randomised controlled trials, of which there are a small number. Reported results for tendinopathies of the shoulder, elbow and heel have shown consistent positive results in favour of ESWT over placebo ESWT in individuals who have failed conservative Therapy. These studies provide strong evidence for ESWT as an effective Therapy for the treatment of chronic treatment-resistant tendinopathies. There is still much debate over several issues surrounding ESWT that have not been adequately addressed by the literature: high- versus low-energy ESWT, Shockwave dosage and number of sessions required for a therapeutic effect. Further research is needed to ascertain the most beneficial protocol for patient care.
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Extracorporeal Shockwave Therapy a review
Sports Medicine, 2002Co-Authors: Bryan Chung, Preston J WileyAbstract:Extracorporeal Shockwave Therapy (ESWT) has been in use for the treatment of tendinopathies since the early 1990s. The exact mechanism by which ESWT relieves tendon-associated pain is not known; however, there is an increasing body of literature that suggests that it can be an effective Therapy for patients who have had repeated nonsurgical treatment failures. The highest strength of evidence is shown in randomised controlled trials, of which there are a small number. Reported results for tendinopathies of the shoulder, elbow and heel have shown consistent positive results in favour of ESWT over placebo ESWT in individuals who have failed conservative Therapy. These studies provide strong evidence for ESWT as an effective Therapy for the treatment of chronic treatment-resistant tendinopathies. There is still much debate over several issues surrounding ESWT that have not been adequately addressed by the literature: high- versus low-energy ESWT, Shockwave dosage and number of sessions required for a therapeutic effect. Further research is needed to ascertain the most beneficial protocol for patient care.
