The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform

Michael J. Fagan - One of the best experts on this subject based on the ideXlab platform.

  • an assessment of the role of the Falx Cerebri and tentorium cerebelli in the cranium of the cat felis silvestris catus
    Journal of the Royal Society Interface, 2018
    Co-Authors: Victor Selles De Lucas, Flora Groning, Alana C Sharp, Hugo Dutel, Susan E. Evans, Peter J Watson, Michael J. Fagan
    Abstract:

    © 2018 The Author(s). The Falx Cerebri and the tentorium cerebelli are two projections of the dura mater in the cranial cavity which ossify to varying degrees in some mammalian species. The idea that the ossification of these structures may be necessary to support the loads arising during feeding has been proposed and dismissed in the past, but never tested quantitatively. To address this, a biomechanical model of a domestic cat (Felis silvestris catus) skull was created and the material properties of the Falx and tentorium were varied for a series of loading regimes incorporating the main masticatory and neck muscles during biting. Under these loading conditions, ossification of the Falx Cerebri does not have a significant impact on the stress in the cranial bones. In the case of the tentorium, however, a localized increase in stress was observed in the parietal and temporal bones, including the tympanic bulla, when a non-ossified tentorium was modelled. These effects were consistent across the different analyses, irrespective of loading regime. The results suggest that ossification of the tentorium cerebelli may play a minor role during feeding activities by decreasing the stress in the back of the skull.

  • an assessment of the role of the Falx Cerebri and tentorium cerebelli in the cranium of the cat felis silvestris catus
    Journal of the Royal Society Interface, 2018
    Co-Authors: Victor Selles De Lucas, Flora Groning, Alana C Sharp, Hugo Dutel, Susan E. Evans, Peter J Watson, Michael J. Fagan
    Abstract:

    The Falx Cerebri and the tentorium cerebelli are two projections of the dura mater in the cranial cavity which ossify to varying degrees in some mammalian species. The idea that the ossification of these structures may be necessary to support the loads arising during feeding has been proposed and dismissed in the past, but never tested quantitatively. To address this, a biomechanical model of a domestic cat (Felis silvestris catus) skull was created and the material properties of the Falx and tentorium were varied for a series of loading regimes incorporating the main masticatory and neck muscles during biting. Under these loading conditions, ossification of the Falx Cerebri does not have a significant impact on the stress in the cranial bones. In the case of the tentorium, however, a localized increase in stress was observed in the parietal and temporal bones, including the tympanic bulla, when a non-ossified tentorium was modelled. These effects were consistent across the different analyses, irrespective of loading regime. The results suggest that ossification of the tentorium cerebelli may play a minor role during feeding activities by decreasing the stress in the back of the skull.

Civan Islak - One of the best experts on this subject based on the ideXlab platform.

  • total agenesis of superior sagittal sinus and Falx Cerebri in a patient who has a subacute subdural hematoma crossing midline case report
    Neurosurgery, 2013
    Co-Authors: Burak Kocak, Zehra Isik Hasiloglu, Osman Kizilkilic, Naci Kocer, Sabri Aydin, Civan Islak
    Abstract:

    Background and importance Anatomic variations of the superior sagittal sinus (SSS) and Falx Cerebri (FC) are uncommon in that agenesis of these structures is extremely rare. We report an extremely rare anatomic variation, total agenesis of the SSS and FC, and briefly discuss it from the anatomical, embryological, radiological, and clinical perspectives. Clinical presentation A 49-year-old woman presented with long-standing headache, gait disturbance, and nausea. Imaging studies showed a bilateral subdural hematoma crossing the midline, dilated venous structures, and perineural cysts, but SSS and FC. Following right-sided hemiparesis and consciousness disturbances, the subdural hematoma was evacuated from a left-sided parietal burr hole because of thick hematoma in this side. After the surgical evacuation, the hemiparesis and consciousness disturbances were regressed; however, she still had severe headache. On account of ongoing headaches and related imaging findings, it was thought that she had possible spontaneous intracranial hypotension. She was treated with autologous epidural blood patch and recovered well. Conclusion Agenesis of the SSS and FC are extremely rare variations. Agenesis of the SSS results in development of alternative venous pathways and may lead to misdiagnosis as dural arteriovenous fistulas. Agenesis of FC may cause diagnostic confusion, because subdural pathologies such as hematomas can cross the midline in rare occasions.

Victor Selles De Lucas - One of the best experts on this subject based on the ideXlab platform.

  • an assessment of the role of the Falx Cerebri and tentorium cerebelli in the cranium of the cat felis silvestris catus
    Journal of the Royal Society Interface, 2018
    Co-Authors: Victor Selles De Lucas, Flora Groning, Alana C Sharp, Hugo Dutel, Susan E. Evans, Peter J Watson, Michael J. Fagan
    Abstract:

    © 2018 The Author(s). The Falx Cerebri and the tentorium cerebelli are two projections of the dura mater in the cranial cavity which ossify to varying degrees in some mammalian species. The idea that the ossification of these structures may be necessary to support the loads arising during feeding has been proposed and dismissed in the past, but never tested quantitatively. To address this, a biomechanical model of a domestic cat (Felis silvestris catus) skull was created and the material properties of the Falx and tentorium were varied for a series of loading regimes incorporating the main masticatory and neck muscles during biting. Under these loading conditions, ossification of the Falx Cerebri does not have a significant impact on the stress in the cranial bones. In the case of the tentorium, however, a localized increase in stress was observed in the parietal and temporal bones, including the tympanic bulla, when a non-ossified tentorium was modelled. These effects were consistent across the different analyses, irrespective of loading regime. The results suggest that ossification of the tentorium cerebelli may play a minor role during feeding activities by decreasing the stress in the back of the skull.

  • an assessment of the role of the Falx Cerebri and tentorium cerebelli in the cranium of the cat felis silvestris catus
    Journal of the Royal Society Interface, 2018
    Co-Authors: Victor Selles De Lucas, Flora Groning, Alana C Sharp, Hugo Dutel, Susan E. Evans, Peter J Watson, Michael J. Fagan
    Abstract:

    The Falx Cerebri and the tentorium cerebelli are two projections of the dura mater in the cranial cavity which ossify to varying degrees in some mammalian species. The idea that the ossification of these structures may be necessary to support the loads arising during feeding has been proposed and dismissed in the past, but never tested quantitatively. To address this, a biomechanical model of a domestic cat (Felis silvestris catus) skull was created and the material properties of the Falx and tentorium were varied for a series of loading regimes incorporating the main masticatory and neck muscles during biting. Under these loading conditions, ossification of the Falx Cerebri does not have a significant impact on the stress in the cranial bones. In the case of the tentorium, however, a localized increase in stress was observed in the parietal and temporal bones, including the tympanic bulla, when a non-ossified tentorium was modelled. These effects were consistent across the different analyses, irrespective of loading regime. The results suggest that ossification of the tentorium cerebelli may play a minor role during feeding activities by decreasing the stress in the back of the skull.

Burak Kocak - One of the best experts on this subject based on the ideXlab platform.

  • total agenesis of superior sagittal sinus and Falx Cerebri in a patient who has a subacute subdural hematoma crossing midline case report
    Neurosurgery, 2013
    Co-Authors: Burak Kocak, Zehra Isik Hasiloglu, Osman Kizilkilic, Naci Kocer, Sabri Aydin, Civan Islak
    Abstract:

    Background and importance Anatomic variations of the superior sagittal sinus (SSS) and Falx Cerebri (FC) are uncommon in that agenesis of these structures is extremely rare. We report an extremely rare anatomic variation, total agenesis of the SSS and FC, and briefly discuss it from the anatomical, embryological, radiological, and clinical perspectives. Clinical presentation A 49-year-old woman presented with long-standing headache, gait disturbance, and nausea. Imaging studies showed a bilateral subdural hematoma crossing the midline, dilated venous structures, and perineural cysts, but SSS and FC. Following right-sided hemiparesis and consciousness disturbances, the subdural hematoma was evacuated from a left-sided parietal burr hole because of thick hematoma in this side. After the surgical evacuation, the hemiparesis and consciousness disturbances were regressed; however, she still had severe headache. On account of ongoing headaches and related imaging findings, it was thought that she had possible spontaneous intracranial hypotension. She was treated with autologous epidural blood patch and recovered well. Conclusion Agenesis of the SSS and FC are extremely rare variations. Agenesis of the SSS results in development of alternative venous pathways and may lead to misdiagnosis as dural arteriovenous fistulas. Agenesis of FC may cause diagnostic confusion, because subdural pathologies such as hematomas can cross the midline in rare occasions.

Fidel Hernandez - One of the best experts on this subject based on the ideXlab platform.

  • Lateral impacts correlate with Falx Cerebri displacement and corpus callosum trauma in sports-related concussions
    Biomechanics and Modeling in Mechanobiology, 2019
    Co-Authors: Fidel Hernandez, Chiara Giordano, Maged Goubran, Sherveen Parivash, Gerald Grant, Michael Zeineh, David Camarillo
    Abstract:

    Corpus callosum trauma has long been implicated in mild traumatic brain injury (mTBI), yet the mechanism by which forces penetrate this structure is unknown. We investigated the hypothesis that coronal and horizontal rotations produce motion of the Falx Cerebri that damages the corpus callosum. We analyzed previously published head kinematics of 115 sports impacts (2 diagnosed mTBI) measured with instrumented mouthguards and used finite element (FE) simulations to correlate Falx displacement with corpus callosum deformation. Peak coronal accelerations were larger in impacts with mTBI (8592 rad/s^2 avg.) than those without (1412 rad/s^2 avg.). From FE simulations, coronal acceleration was strongly correlated with deep lateral motion of the Falx center ( r  = 0.85), while horizontal acceleration was correlated with deep lateral motion of the Falx periphery ( r  > 0.78). Larger lateral displacement at the Falx center and periphery was correlated with higher tract-oriented strains in the corpus callosum body ( r  = 0.91) and genu/splenium ( r  > 0.72), respectively. The relationship between the corpus callosum and Falx was unique: removing the Falx from the FE model halved peak strains in the corpus callosum from 35% to 17%. Consistent with model results, we found indications of corpus callosum trauma in diffusion tensor imaging of the mTBI athletes. For a measured alteration of consciousness, depressed fractional anisotropy and increased mean diffusivity indicated possible damage to the mid-posterior corpus callosum. Our results suggest that the corpus callosum may be sensitive to coronal and horizontal rotations because they drive lateral motion of a relatively stiff membrane, the Falx, in the direction of commissural fibers below.

  • coronal head rotation Falx Cerebri displacement and corpus callosum strain are related and implicated in sports related mtbi
    Journal of Neurotrauma, 2016
    Co-Authors: Fidel Hernandez, Chiara Giordano, Svein Kleiven, David B Camarillo
    Abstract:

    CORONAL HEAD ROTATION, Falx Cerebri DISPLACEMENT, AND CORPUS CALLOSUM STRAIN ARE RELATED AND IMPLICATED IN SPORTS-RELATED MTBI