Fibromyalgia

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Frederick Wolfe - One of the best experts on this subject based on the ideXlab platform.

  • Fibromyalgia diagnosis and biased assessment sex prevalence and bias
    PLOS ONE, 2018
    Co-Authors: Frederick Wolfe, Brian Walitt, S Perrot, Johannes J Rasker, Winfried Hauser
    Abstract:

    Purpose Multiple clinical and epidemiological studies have provided estimates of Fibromyalgia prevalence and sex ratio, but different criteria sets and methodology, as well as bias, have led to widely varying (0.4%->11%) estimates of prevalence and female predominance (>90% to <61%). In general, studies have failed to distinguish Criteria based Fibromyalgia (CritFM) from Clinical Fibromyalgia (ClinFM). In the current study we compare CritFM with ClinFM to investigate gender and other biases in the diagnosis of Fibromyalgia. Methods We used a rheumatic disease databank and 2016 Fibromyalgia criteria to study prevalence and sex ratios in a selection biased sample of 1761 referred and diagnosed Fibromyalgia patients and in an unbiased sample of 4342 patients with no diagnosis with respect to Fibromyalgia. We compared diagnostic and clinical variables according to gender, and we reanalyzed a German population study (GPS) (n = 2435) using revised 2016 criteria for Fibromyalgia. Results In the selection-biased sample of referred patients with Fibromyalgia, more than 90% were women. However, when an unselected sample of rheumatoid arthritis (RA) patients was studied for the presence of Fibromyalgia, women represented 58.7% of Fibromyalgia cases. Women had slightly more symptoms than men, including generalized pain (36.8% vs. 32.4%), count of 37 symptoms (4.7 vs. 3.7) and mean polysymptomatic distress scores (10.2 vs. 8.2). We also found a linear relation between the probability of being females and Fibromyalgia and Fibromyalgia severity. Women in the GPS represented 59.2% of cases. Discussion The perception of Fibromyalgia as almost exclusively (≥90%) a women’s disorder is not supported by data in unbiased studies. Using validated self-report criteria and unbiased selection, the female proportion of Fibromyalgia cases was ≤60% in the unbiased studies, and the observed CritFM prevalence of Fibromyalgia in the GPS was ~2%. ClinFM is the public face of Fibromyalgia, but is severely affected by selection and confirmation bias in the clinic and publications, underestimating men with Fibromyalgia and overestimating women. We recommend the use of 2016 Fibromyalgia criteria for clinical diagnosis and epidemiology because of its updated scoring and generalized pain requirement. Fibromyalgia and generalized pain positivity, widespread pain (WPI), symptom severity scale (SSS) and polysymptomatic distress (PSD) scale should always be reported.

  • three quarters of persons in the us population reporting a clinical diagnosis of Fibromyalgia do not satisfy Fibromyalgia criteria the 2012 national health interview survey
    PLOS ONE, 2016
    Co-Authors: Brian Walitt, Robert S Katz, Martin J Bergman, Frederick Wolfe
    Abstract:

    Objectives Although Fibromyalgia criteria have been in effect for decades, little is known about how the Fibromyalgia diagnosis is applied and understood by clinicians and patients. We used the National Health Interview Survey (NHIS) to determine the prevalence of self-reported clinician diagnosed Fibromyalgia and then compared demographics, symptoms, disability and medical utilization measures of persons with a clinical diagnosis of Fibromyalgia that did not meet diagnostic criteria (false-positive or prior [F/P] Fibromyalgia) to persons with and without criteria-positive Fibromyalgia.

  • the prevalence and characteristics of Fibromyalgia in the 2012 national health interview survey
    PLOS ONE, 2015
    Co-Authors: Brian Walitt, Robert S Katz, Martin J Bergman, Richard L Nahin, Frederick Wolfe
    Abstract:

    Background Most knowledge of Fibromyalgia comes from the clinical setting, where healthcare-seeking behavior and selection issues influence study results. The characteristics of Fibromyalgia in the general population have not been studied in detail. Methods We developed and tested surrogate study specific criteria for Fibromyalgia in rheumatology practices using variables from the US National Health Interview Survey (NHIS) and the modification (for surveys) of the 2010 American College of Rheumatology (ACR) preliminary Fibromyalgia criteria. The surrogate criteria were applied to the 2012 NHIS and identified persons who satisfied criteria from symptom data. The NHIS weighted sample of 8446 persons represents 225.7 million US adults. Results Fibromyalgia was identified in 1.75% (95% CI 1.42, 2.07), or 3.94 million persons. However, 73% of identified cases self-reported a physician’s diagnosis other than Fibromyalgia. Identified cases had high levels of self-reported pain, non-pain symptoms, comorbidity, psychological distress, medical costs, Social Security and work disability. Caseness was associated with gender, education, ethnicity, citizenship and unhealthy behaviors. Demographics, behaviors, and comorbidity were predictive of case status. Examination of the surrogate polysymptomatic distress scale (PSD) of the 2010 ACR criteria found Fibromyalgia symptoms extending through the full length of the scale. Conclusions Persons identified with criteria-based Fibromyalgia have severe symptoms, but most (73%) have not received a clinical diagnosis of Fibromyalgia. The association of Fibromyalgia-like symptoms over the full length of the PSD scale with physiological as well as mental stressors suggests PSD may be a universal response variable rather than one restricted to Fibromyalgia.

  • the development of Fibromyalgia i examination of rates and predictors in patients with rheumatoid arthritis ra
    Pain, 2011
    Co-Authors: Frederick Wolfe, Winfried Hauser, Afton L Hassett, Robert S Katz, Brian Walitt
    Abstract:

    We determined rates and predictors of future development of Fibromyalgia in patients with rheumatoid arthritis (RA). After excluding patients with Fibromyalgia and those with high levels of Fibromyalgia symptoms (Fibromyalgianess score>10) at baseline, we studied Fibromyalgia development in 9739 RA patients during 42,591 patient-years of follow-up. We defined Fibromyalgia using a modification of the ACR 2010 Fibromyalgia criteria. We used Cox regression to predict future Fibromyalgia, and examined the accuracy of predictions using Harrell's C concordance coefficient. At the last observation, 7.4% of patients satisfied criteria, although 19.8% satisfied criteria at some point during follow-up, an incidence rate of 5.3 (95% CI 5.1, 5.6) per 100 patients years, and at rates that were similar in men (7.0%) and women (8.1%). Among those satisfying criteria, during 11,363 years of follow-up from the time of first Fibromyalgia diagnosis, half of follow-up time was Fibromyalgia+and was associated with markedly abnormal RA variable and FM variable scores. Demographic factors were weak predictors of Fibromyalgia (C=0.604). Demographic plus RA variables (C=0.720) and demographic plus Fibromyalgia variables (C=0.765), and all predictors (C=0.782) increased accuracy. Clinically important hazard ratios were noted for cognition, depression, comorbidity, and high levels of RA and FM continuous variables Overall, study results indicate that multiple, inter-correlated factors that include social disadvantage, psychological distress, comorbidity, RA severity, and Fibromyalgia variables predict future development of Fibromyalgia, but there is little evidence of the effect of underlying causes. After diagnosis, patients move in both directions across the diagnostic criteria cut points.

Guevara Ruiz, Juan Camilo - One of the best experts on this subject based on the ideXlab platform.

  • Characterization of the population with Fibromyalgia in a High Complexity Hospital, Bogotá D.C. Colombia 2018 - 2019
    Escuela de Medicina y Ciencias de la Salud, 2021
    Co-Authors: Arce Gutierrez, Juliana Elvira, Guevara Ruiz, Juan Camilo
    Abstract:

    Antecedentes: La fibromialgia presenta una alta prevalencia en la población general, varía según los criterios diagnósticos utilizados debido a su etiología multidimensional y fisiopatología compleja. Como trastorno de la regulación del dolor, es necesario conocer las características sociodemográficas y comorbilidades que inciden en esta enfermedad para construir intervenciones integrales y preservar la funcionalidad de los pacientes. Metodología: Estudio observacional descriptivo de corte transversal, ejecutando una búsqueda en 6689 historias clínicas, correspondientes a 1001 pacientes de la consulta externa del servicio de dolor y cuidados paliativos de Méderi (2018 – 2019). 116 tuvieron diagnóstico de fibromialgia y cumplieron con los criterios de inclusión. Resultados: De los 116 pacientes con diagnóstico de fibromialgia el 94% son mujeres, 84,4% con 50 años o más, 67,2% tenían comorbilidad reumatológica y 56% comorbilidad psiquiátrica, con consumo de 3 o más medicamentos en un 81%, uso de medicamentos opioides en el 75%; 83,3% recibieron manejo no farmacológico. Los criterios diagnósticos para fibromialgia se aplicaron en el 43,1% de los pacientes. Se evidenció que el 10,3% contaban con incapacidad temporal y el 7,8% tenían pensión por invalidez. Conclusión: La fibromialgia constituye una patología relevante en la consulta de las clínicas de dolor, requiriendo de múltiples intervenciones para su manejo y cuyo impacto es difícil de medir y podría representar una carga significativa de morbilidad para los pacientes, en el desempeño de su rol laboral y económica al sistema de salud.Background: Fibromyalgia has a high prevalence in the general population, it varies according to the diagnostic criteria used due to its multidimensional etiology and complex pathophysiology. As a disorder of pain regulation, it is necessary to know the sociodemographic characteristics and comorbidities that affect this disease to build comprehensive interventions and preserve the functionality of patients. Methodology: Observational descriptive cross-sectional study, executing a search in 6689 medical records, corresponding to 1001 patients from the outpatient department of the pain and palliative care service in Méderi (2018 - 2019). 116 had a diagnosis of Fibromyalgia and met the inclusion criteria. Results: Of the 116 patients diagnosed with Fibromyalgia, 94% are women, 84.4% with 50 years or more, 67.2% had rheumatic comorbidity and 56% had psychiatric comorbidity, with consumption of 3 or more medications in 81% , use of opioid medications in 75%; 83.3% received non-pharmacological management. The diagnostic criteria for Fibromyalgia were applied in 43.1% of the patients. It was evident that 10.3% had temporary disability and 7.8% had a disability pension. Conclusion: Fibromyalgia is a relevant pathology in the pain medicine clinic, requiring multiple interventions for its management and whose impact is difficult to measure and could represent a significant burden of morbidity for patients, in the performance of their job role and the economic impact to the health system.2020-08-04 11:35:01: Script de automatizacion de embargos. Correo recibido: uliana Elvira Arce Gutierrez Mar 4/08/2020 8:42 AM Cordial saludo, Solicito por medio de la presente solicito sea bloqueada para publicación mi tesis de grado Caracterización de la población con diagnóstico de Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019 por 8 meses, con el fin de presentarlo para publicación como articulo en revista indexada. Agradezco su amable atención. Juliana Arce Gutiérrez Esp. Medicina del Dolor y Cuidado Paliativo - Respuesta: Repositorio Institucional EdocUR Mar 4/08/2020 11:30 AM Respetado Doctor Julian Arce, Hemos realizado la publicación de su documento: Caracterización de la población con Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019, el cual puede consultar en el siguiente enlace: https://repository.urosario.edu.co/handle/10336/25836 De acuerdo con su solicitud, el documento ha quedado embargado hasta el (2021-04-04) en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica. Quedamos atentos a cualquier inquietud o sugerencia

  • Characterization of the population with Fibromyalgia in a High Complexity Hospital, Bogotá D.C. Colombia 2018 - 2019
    Escuela de Medicina y Ciencias de la Salud, 2020
    Co-Authors: Arce Gutierrez, Juliana Elvira, Guevara Ruiz, Juan Camilo
    Abstract:

    Antecedentes: La fibromialgia presenta una alta prevalencia en la población general, varía según los criterios diagnósticos utilizados debido a su etiología multidimensional y fisiopatología compleja. Como trastorno de la regulación del dolor, es necesario conocer las características sociodemográficas y comorbilidades que inciden en esta enfermedad para construir intervenciones integrales y preservar la funcionalidad de los pacientes. Metodología: Estudio observacional descriptivo de corte transversal, ejecutando una búsqueda en 6689 historias clínicas, correspondientes a 1001 pacientes de la consulta externa del servicio de dolor y cuidados paliativos de Méderi (2018 – 2019). 116 tuvieron diagnóstico de fibromialgia y cumplieron con los criterios de inclusión. Resultados: De los 116 pacientes con diagnóstico de fibromialgia el 94% son mujeres, 84,4% con 50 años o más, 67,2% tenían comorbilidad reumatológica y 56% comorbilidad psiquiátrica, con consumo de 3 o más medicamentos en un 81%, uso de medicamentos opioides en el 75%; 83,3% recibieron manejo no farmacológico. Los criterios diagnósticos para fibromialgia se aplicaron en el 43,1% de los pacientes. Se evidenció que el 10,3% contaban con incapacidad temporal y el 7,8% tenían pensión por invalidez. Conclusión: La fibromialgia constituye una patología relevante en la consulta de las clínicas de dolor, requiriendo de múltiples intervenciones para su manejo y cuyo impacto es difícil de medir y podría representar una carga significativa de morbilidad para los pacientes, en el desempeño de su rol laboral y económica al sistema de salud.Background: Fibromyalgia has a high prevalence in the general population, it varies according to the diagnostic criteria used due to its multidimensional etiology and complex pathophysiology. As a disorder of pain regulation, it is necessary to know the sociodemographic characteristics and comorbidities that affect this disease to build comprehensive interventions and preserve the functionality of patients. Methodology: Observational descriptive cross-sectional study, executing a search in 6689 medical records, corresponding to 1001 patients from the outpatient department of the pain and palliative care service in Méderi (2018 - 2019). 116 had a diagnosis of Fibromyalgia and met the inclusion criteria. Results: Of the 116 patients diagnosed with Fibromyalgia, 94% are women, 84.4% with 50 years or more, 67.2% had rheumatic comorbidity and 56% had psychiatric comorbidity, with consumption of 3 or more medications in 81% , use of opioid medications in 75%; 83.3% received non-pharmacological management. The diagnostic criteria for Fibromyalgia were applied in 43.1% of the patients. It was evident that 10.3% had temporary disability and 7.8% had a disability pension. Conclusion: Fibromyalgia is a relevant pathology in the pain medicine clinic, requiring multiple interventions for its management and whose impact is difficult to measure and could represent a significant burden of morbidity for patients, in the performance of their job role and the economic impact to the health system.2021-04-04 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2021-04-032020-08-04 11:35:01: Script de automatizacion de embargos. Correo recibido: uliana Elvira Arce Gutierrez Mar 4/08/2020 8:42 AM Cordial saludo, Solicito por medio de la presente solicito sea bloqueada para publicación mi tesis de grado Caracterización de la población con diagnóstico de Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019 por 8 meses, con el fin de presentarlo para publicación como articulo en revista indexada. Agradezco su amable atención. Juliana Arce Gutiérrez Esp. Medicina del Dolor y Cuidado Paliativo - Respuesta: Repositorio Institucional EdocUR Mar 4/08/2020 11:30 AM Respetado Doctor Julian Arce, Hemos realizado la publicación de su documento: Caracterización de la población con Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019, el cual puede consultar en el siguiente enlace: https://repository.urosario.edu.co/handle/10336/25836 De acuerdo con su solicitud, el documento ha quedado embargado hasta el (2021-04-04) en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica. Quedamos atentos a cualquier inquietud o sugerencia

Brian Walitt - One of the best experts on this subject based on the ideXlab platform.

  • Fibromyalgia diagnosis and biased assessment sex prevalence and bias
    PLOS ONE, 2018
    Co-Authors: Frederick Wolfe, Brian Walitt, S Perrot, Johannes J Rasker, Winfried Hauser
    Abstract:

    Purpose Multiple clinical and epidemiological studies have provided estimates of Fibromyalgia prevalence and sex ratio, but different criteria sets and methodology, as well as bias, have led to widely varying (0.4%->11%) estimates of prevalence and female predominance (>90% to <61%). In general, studies have failed to distinguish Criteria based Fibromyalgia (CritFM) from Clinical Fibromyalgia (ClinFM). In the current study we compare CritFM with ClinFM to investigate gender and other biases in the diagnosis of Fibromyalgia. Methods We used a rheumatic disease databank and 2016 Fibromyalgia criteria to study prevalence and sex ratios in a selection biased sample of 1761 referred and diagnosed Fibromyalgia patients and in an unbiased sample of 4342 patients with no diagnosis with respect to Fibromyalgia. We compared diagnostic and clinical variables according to gender, and we reanalyzed a German population study (GPS) (n = 2435) using revised 2016 criteria for Fibromyalgia. Results In the selection-biased sample of referred patients with Fibromyalgia, more than 90% were women. However, when an unselected sample of rheumatoid arthritis (RA) patients was studied for the presence of Fibromyalgia, women represented 58.7% of Fibromyalgia cases. Women had slightly more symptoms than men, including generalized pain (36.8% vs. 32.4%), count of 37 symptoms (4.7 vs. 3.7) and mean polysymptomatic distress scores (10.2 vs. 8.2). We also found a linear relation between the probability of being females and Fibromyalgia and Fibromyalgia severity. Women in the GPS represented 59.2% of cases. Discussion The perception of Fibromyalgia as almost exclusively (≥90%) a women’s disorder is not supported by data in unbiased studies. Using validated self-report criteria and unbiased selection, the female proportion of Fibromyalgia cases was ≤60% in the unbiased studies, and the observed CritFM prevalence of Fibromyalgia in the GPS was ~2%. ClinFM is the public face of Fibromyalgia, but is severely affected by selection and confirmation bias in the clinic and publications, underestimating men with Fibromyalgia and overestimating women. We recommend the use of 2016 Fibromyalgia criteria for clinical diagnosis and epidemiology because of its updated scoring and generalized pain requirement. Fibromyalgia and generalized pain positivity, widespread pain (WPI), symptom severity scale (SSS) and polysymptomatic distress (PSD) scale should always be reported.

  • three quarters of persons in the us population reporting a clinical diagnosis of Fibromyalgia do not satisfy Fibromyalgia criteria the 2012 national health interview survey
    PLOS ONE, 2016
    Co-Authors: Brian Walitt, Robert S Katz, Martin J Bergman, Frederick Wolfe
    Abstract:

    Objectives Although Fibromyalgia criteria have been in effect for decades, little is known about how the Fibromyalgia diagnosis is applied and understood by clinicians and patients. We used the National Health Interview Survey (NHIS) to determine the prevalence of self-reported clinician diagnosed Fibromyalgia and then compared demographics, symptoms, disability and medical utilization measures of persons with a clinical diagnosis of Fibromyalgia that did not meet diagnostic criteria (false-positive or prior [F/P] Fibromyalgia) to persons with and without criteria-positive Fibromyalgia.

  • the prevalence and characteristics of Fibromyalgia in the 2012 national health interview survey
    PLOS ONE, 2015
    Co-Authors: Brian Walitt, Robert S Katz, Martin J Bergman, Richard L Nahin, Frederick Wolfe
    Abstract:

    Background Most knowledge of Fibromyalgia comes from the clinical setting, where healthcare-seeking behavior and selection issues influence study results. The characteristics of Fibromyalgia in the general population have not been studied in detail. Methods We developed and tested surrogate study specific criteria for Fibromyalgia in rheumatology practices using variables from the US National Health Interview Survey (NHIS) and the modification (for surveys) of the 2010 American College of Rheumatology (ACR) preliminary Fibromyalgia criteria. The surrogate criteria were applied to the 2012 NHIS and identified persons who satisfied criteria from symptom data. The NHIS weighted sample of 8446 persons represents 225.7 million US adults. Results Fibromyalgia was identified in 1.75% (95% CI 1.42, 2.07), or 3.94 million persons. However, 73% of identified cases self-reported a physician’s diagnosis other than Fibromyalgia. Identified cases had high levels of self-reported pain, non-pain symptoms, comorbidity, psychological distress, medical costs, Social Security and work disability. Caseness was associated with gender, education, ethnicity, citizenship and unhealthy behaviors. Demographics, behaviors, and comorbidity were predictive of case status. Examination of the surrogate polysymptomatic distress scale (PSD) of the 2010 ACR criteria found Fibromyalgia symptoms extending through the full length of the scale. Conclusions Persons identified with criteria-based Fibromyalgia have severe symptoms, but most (73%) have not received a clinical diagnosis of Fibromyalgia. The association of Fibromyalgia-like symptoms over the full length of the PSD scale with physiological as well as mental stressors suggests PSD may be a universal response variable rather than one restricted to Fibromyalgia.

  • the development of Fibromyalgia i examination of rates and predictors in patients with rheumatoid arthritis ra
    Pain, 2011
    Co-Authors: Frederick Wolfe, Winfried Hauser, Afton L Hassett, Robert S Katz, Brian Walitt
    Abstract:

    We determined rates and predictors of future development of Fibromyalgia in patients with rheumatoid arthritis (RA). After excluding patients with Fibromyalgia and those with high levels of Fibromyalgia symptoms (Fibromyalgianess score>10) at baseline, we studied Fibromyalgia development in 9739 RA patients during 42,591 patient-years of follow-up. We defined Fibromyalgia using a modification of the ACR 2010 Fibromyalgia criteria. We used Cox regression to predict future Fibromyalgia, and examined the accuracy of predictions using Harrell's C concordance coefficient. At the last observation, 7.4% of patients satisfied criteria, although 19.8% satisfied criteria at some point during follow-up, an incidence rate of 5.3 (95% CI 5.1, 5.6) per 100 patients years, and at rates that were similar in men (7.0%) and women (8.1%). Among those satisfying criteria, during 11,363 years of follow-up from the time of first Fibromyalgia diagnosis, half of follow-up time was Fibromyalgia+and was associated with markedly abnormal RA variable and FM variable scores. Demographic factors were weak predictors of Fibromyalgia (C=0.604). Demographic plus RA variables (C=0.720) and demographic plus Fibromyalgia variables (C=0.765), and all predictors (C=0.782) increased accuracy. Clinically important hazard ratios were noted for cognition, depression, comorbidity, and high levels of RA and FM continuous variables Overall, study results indicate that multiple, inter-correlated factors that include social disadvantage, psychological distress, comorbidity, RA severity, and Fibromyalgia variables predict future development of Fibromyalgia, but there is little evidence of the effect of underlying causes. After diagnosis, patients move in both directions across the diagnostic criteria cut points.

Robert M Bennett - One of the best experts on this subject based on the ideXlab platform.

  • Fibromyalgia chronic fatigue syndrome and myofascial pain
    Current Opinion in Rheumatology, 1998
    Co-Authors: Robert M Bennett
    Abstract:

    : Epidemiologic studies continue to provide evidence that Fibromyalgia is part of a spectrum of chronic widespread pain. The prevalence of chronic widespread pain is several times higher than Fibromyalgia as defined by the 1990 American College of Rheumatology guidelines. There is now compelling evidence of a familial clustering of Fibromyalgia cases in female sufferers; whether this clustering results from nature or nature remains to be elucidated. A wide spectrum of Fibromyalgia-associated symptomatology and syndromes continues to be described. During the past year the association with interstitial cystitis has been explored, and neurally mediated hypotension has been documented in both Fibromyalgia and chronic fatigue syndrome. Abnormalities of the growth hormone-insulin-like growth factor-1 axis have been also documented in both Fibromyalgia and chronic fatigue syndrome. The commonly reported but anecdotal association of Fibromyalgia with whiplash-type neck trauma was validated in a report from Israel. However, unlike North America, 100% of Israeli patients with posttraumatic Fibromyalgia returned to work. Basic research in Fibromyalgia continues to pinpoint abnormal sensory processing as being integral to understanding Fibromyalgia pain. Drugs such as ketamine, which block N-methyl-D-aspartate receptors (which are often upregulated in central pain states) were shown to benefit Fibromyalgia pain in an experimental setting. The combination of fluoxetine and amitriptyline was reported to be more beneficial than either drug alone in patients with Fibromyalgia. A high prevalence of autoantibodies to cytoskeletal and nuclear envelope proteins was found in chronic fatigue syndrome, and an increased prevalence of antipolymer antibodies was found in symptomatic silicone breast implant recipients who often have Fibromyalgia.

Arce Gutierrez, Juliana Elvira - One of the best experts on this subject based on the ideXlab platform.

  • Characterization of the population with Fibromyalgia in a High Complexity Hospital, Bogotá D.C. Colombia 2018 - 2019
    Escuela de Medicina y Ciencias de la Salud, 2021
    Co-Authors: Arce Gutierrez, Juliana Elvira, Guevara Ruiz, Juan Camilo
    Abstract:

    Antecedentes: La fibromialgia presenta una alta prevalencia en la población general, varía según los criterios diagnósticos utilizados debido a su etiología multidimensional y fisiopatología compleja. Como trastorno de la regulación del dolor, es necesario conocer las características sociodemográficas y comorbilidades que inciden en esta enfermedad para construir intervenciones integrales y preservar la funcionalidad de los pacientes. Metodología: Estudio observacional descriptivo de corte transversal, ejecutando una búsqueda en 6689 historias clínicas, correspondientes a 1001 pacientes de la consulta externa del servicio de dolor y cuidados paliativos de Méderi (2018 – 2019). 116 tuvieron diagnóstico de fibromialgia y cumplieron con los criterios de inclusión. Resultados: De los 116 pacientes con diagnóstico de fibromialgia el 94% son mujeres, 84,4% con 50 años o más, 67,2% tenían comorbilidad reumatológica y 56% comorbilidad psiquiátrica, con consumo de 3 o más medicamentos en un 81%, uso de medicamentos opioides en el 75%; 83,3% recibieron manejo no farmacológico. Los criterios diagnósticos para fibromialgia se aplicaron en el 43,1% de los pacientes. Se evidenció que el 10,3% contaban con incapacidad temporal y el 7,8% tenían pensión por invalidez. Conclusión: La fibromialgia constituye una patología relevante en la consulta de las clínicas de dolor, requiriendo de múltiples intervenciones para su manejo y cuyo impacto es difícil de medir y podría representar una carga significativa de morbilidad para los pacientes, en el desempeño de su rol laboral y económica al sistema de salud.Background: Fibromyalgia has a high prevalence in the general population, it varies according to the diagnostic criteria used due to its multidimensional etiology and complex pathophysiology. As a disorder of pain regulation, it is necessary to know the sociodemographic characteristics and comorbidities that affect this disease to build comprehensive interventions and preserve the functionality of patients. Methodology: Observational descriptive cross-sectional study, executing a search in 6689 medical records, corresponding to 1001 patients from the outpatient department of the pain and palliative care service in Méderi (2018 - 2019). 116 had a diagnosis of Fibromyalgia and met the inclusion criteria. Results: Of the 116 patients diagnosed with Fibromyalgia, 94% are women, 84.4% with 50 years or more, 67.2% had rheumatic comorbidity and 56% had psychiatric comorbidity, with consumption of 3 or more medications in 81% , use of opioid medications in 75%; 83.3% received non-pharmacological management. The diagnostic criteria for Fibromyalgia were applied in 43.1% of the patients. It was evident that 10.3% had temporary disability and 7.8% had a disability pension. Conclusion: Fibromyalgia is a relevant pathology in the pain medicine clinic, requiring multiple interventions for its management and whose impact is difficult to measure and could represent a significant burden of morbidity for patients, in the performance of their job role and the economic impact to the health system.2020-08-04 11:35:01: Script de automatizacion de embargos. Correo recibido: uliana Elvira Arce Gutierrez Mar 4/08/2020 8:42 AM Cordial saludo, Solicito por medio de la presente solicito sea bloqueada para publicación mi tesis de grado Caracterización de la población con diagnóstico de Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019 por 8 meses, con el fin de presentarlo para publicación como articulo en revista indexada. Agradezco su amable atención. Juliana Arce Gutiérrez Esp. Medicina del Dolor y Cuidado Paliativo - Respuesta: Repositorio Institucional EdocUR Mar 4/08/2020 11:30 AM Respetado Doctor Julian Arce, Hemos realizado la publicación de su documento: Caracterización de la población con Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019, el cual puede consultar en el siguiente enlace: https://repository.urosario.edu.co/handle/10336/25836 De acuerdo con su solicitud, el documento ha quedado embargado hasta el (2021-04-04) en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica. Quedamos atentos a cualquier inquietud o sugerencia

  • Characterization of the population with Fibromyalgia in a High Complexity Hospital, Bogotá D.C. Colombia 2018 - 2019
    Escuela de Medicina y Ciencias de la Salud, 2020
    Co-Authors: Arce Gutierrez, Juliana Elvira, Guevara Ruiz, Juan Camilo
    Abstract:

    Antecedentes: La fibromialgia presenta una alta prevalencia en la población general, varía según los criterios diagnósticos utilizados debido a su etiología multidimensional y fisiopatología compleja. Como trastorno de la regulación del dolor, es necesario conocer las características sociodemográficas y comorbilidades que inciden en esta enfermedad para construir intervenciones integrales y preservar la funcionalidad de los pacientes. Metodología: Estudio observacional descriptivo de corte transversal, ejecutando una búsqueda en 6689 historias clínicas, correspondientes a 1001 pacientes de la consulta externa del servicio de dolor y cuidados paliativos de Méderi (2018 – 2019). 116 tuvieron diagnóstico de fibromialgia y cumplieron con los criterios de inclusión. Resultados: De los 116 pacientes con diagnóstico de fibromialgia el 94% son mujeres, 84,4% con 50 años o más, 67,2% tenían comorbilidad reumatológica y 56% comorbilidad psiquiátrica, con consumo de 3 o más medicamentos en un 81%, uso de medicamentos opioides en el 75%; 83,3% recibieron manejo no farmacológico. Los criterios diagnósticos para fibromialgia se aplicaron en el 43,1% de los pacientes. Se evidenció que el 10,3% contaban con incapacidad temporal y el 7,8% tenían pensión por invalidez. Conclusión: La fibromialgia constituye una patología relevante en la consulta de las clínicas de dolor, requiriendo de múltiples intervenciones para su manejo y cuyo impacto es difícil de medir y podría representar una carga significativa de morbilidad para los pacientes, en el desempeño de su rol laboral y económica al sistema de salud.Background: Fibromyalgia has a high prevalence in the general population, it varies according to the diagnostic criteria used due to its multidimensional etiology and complex pathophysiology. As a disorder of pain regulation, it is necessary to know the sociodemographic characteristics and comorbidities that affect this disease to build comprehensive interventions and preserve the functionality of patients. Methodology: Observational descriptive cross-sectional study, executing a search in 6689 medical records, corresponding to 1001 patients from the outpatient department of the pain and palliative care service in Méderi (2018 - 2019). 116 had a diagnosis of Fibromyalgia and met the inclusion criteria. Results: Of the 116 patients diagnosed with Fibromyalgia, 94% are women, 84.4% with 50 years or more, 67.2% had rheumatic comorbidity and 56% had psychiatric comorbidity, with consumption of 3 or more medications in 81% , use of opioid medications in 75%; 83.3% received non-pharmacological management. The diagnostic criteria for Fibromyalgia were applied in 43.1% of the patients. It was evident that 10.3% had temporary disability and 7.8% had a disability pension. Conclusion: Fibromyalgia is a relevant pathology in the pain medicine clinic, requiring multiple interventions for its management and whose impact is difficult to measure and could represent a significant burden of morbidity for patients, in the performance of their job role and the economic impact to the health system.2021-04-04 01:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2021-04-032020-08-04 11:35:01: Script de automatizacion de embargos. Correo recibido: uliana Elvira Arce Gutierrez Mar 4/08/2020 8:42 AM Cordial saludo, Solicito por medio de la presente solicito sea bloqueada para publicación mi tesis de grado Caracterización de la población con diagnóstico de Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019 por 8 meses, con el fin de presentarlo para publicación como articulo en revista indexada. Agradezco su amable atención. Juliana Arce Gutiérrez Esp. Medicina del Dolor y Cuidado Paliativo - Respuesta: Repositorio Institucional EdocUR Mar 4/08/2020 11:30 AM Respetado Doctor Julian Arce, Hemos realizado la publicación de su documento: Caracterización de la población con Fibromialgia en un Hospital de alta Complejidad, Bogotá D.C. Colombia 2018 – 2019, el cual puede consultar en el siguiente enlace: https://repository.urosario.edu.co/handle/10336/25836 De acuerdo con su solicitud, el documento ha quedado embargado hasta el (2021-04-04) en concordancia con las Políticas de Acceso Abierto de la Universidad. Si usted desea dejarlo con acceso abierto antes de finalizar dicho periodo o si por el contrario desea extender el embargo al finalizar este tiempo, puede enviar un correo a esta misma dirección realizando la solicitud. Tenga en cuenta que los documentos en acceso abierto propician una mayor visibilidad de su producción académica. Quedamos atentos a cualquier inquietud o sugerencia