The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Andreas Kranawetvogl - One of the best experts on this subject based on the ideXlab platform.

  • determination of the synthetic antioxidant ethoxyquin and its metabolites in fish and Fishery Products using liquid chromatography fluorescence detection and stable isotope dilution analysis liquid chromatography tandem mass spectrometry
    Journal of Agricultural and Food Chemistry, 2019
    Co-Authors: Andreas Kranawetvogl, Paul W Elsinghors
    Abstract:

    The use of the synthetic antioxidant ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) as a flame retardant in fish meal transported by sea is required by international authorities to prevent self-ignition. Because of extensive carry-over within the food chain, selective and sensitive analytical methods are required for investigations on human exposure and the safety of EQ and its metabolites. Therefore, a simple, fast, and rugged liquid-chromatography (LC) method was developed for the detection of EQ and its metabolites in fish and Fishery Products after liquid–liquid extraction using QuEChERS. For screening purposes, a fluorescence detector was used (LC-FLD) with the EQ-analogue methoxyquin serving as an internal standard. For stable-isotope dilution analysis by liquid chromatography–tandem mass spectrometry (SIDA-LC-MS/MS), deuterated analogues of EQ and its metabolites were synthesized for the first time and allowed for sensitive quantification and thus confirmation of screening results. ...

  • determination of the synthetic antioxidant ethoxyquin and its metabolites in fish and Fishery Products using liquid chromatography fluorescence detection and stable isotope dilution analysis liquid chromatography tandem mass spectrometry
    Journal of Agricultural and Food Chemistry, 2019
    Co-Authors: Andreas Kranawetvogl, Paul W Elsinghorst
    Abstract:

    The use of the synthetic antioxidant ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) as a flame retardant in fish meal transported by sea is required by international authorities to prevent self-ignition. Because of extensive carry-over within the food chain, selective and sensitive analytical methods are required for investigations on human exposure and the safety of EQ and its metabolites. Therefore, a simple, fast, and rugged liquid-chromatography (LC) method was developed for the detection of EQ and its metabolites in fish and Fishery Products after liquid-liquid extraction using QuEChERS. For screening purposes, a fluorescence detector was used (LC-FLD) with the EQ-analogue methoxyquin serving as an internal standard. For stable-isotope dilution analysis by liquid chromatography-tandem mass spectrometry (SIDA-LC-MS/MS), deuterated analogues of EQ and its metabolites were synthesized for the first time and allowed for sensitive quantification and thus confirmation of screening results. Both methods were validated and successfully applied to commercially available fish samples.

Gyu-seek Rhee - One of the best experts on this subject based on the ideXlab platform.

  • multi residue determination of veterinary drugs in Fishery Products using liquid chromatography tandem mass spectrometry
    Food Analytical Methods, 2018
    Co-Authors: Dasom Shin, Hui-seung Kang, Jiyoon Jeong, Joohye Kim, Won Jo Choe, Kwangsoo Lee, Gyu-seek Rhee
    Abstract:

    The aim of the present study was to develop a multi-residue confirmation method for the analysis of veterinary drugs in Fishery Products using liquid chromatography-tandem mass spectrometry. The chosen veterinary drugs, which are legally authorized compounds in Korea, were categorized into chemical classes such as amphenicols, cephalosporins, fluoroquinolones, macrolides, penicillins, pleuromutilins, sulfonamides, and tetracyclines. Sample extraction and cleanup were evaluated based on a modified quick, easy, cheap, effective, rugged, and safe procedure using octadecylsilane and primary secondary amine sorbents for purification. Extractions were carried out using an ammonium acetate buffer and ethylenediaminetetraacetic acid disodium salt (pH 4.0) with the addition of ammonium formate in water/acetonitrile. Instrumental analysis was performed using positive/negative ionization in the multiple reaction monitoring mode. The chromatographic conditions were optimized to give run time of  0.98 using matrix-matched calibrations constructed at six different concentrations. The proposed method was applied to the analysis of 403 real samples obtained from domestic markets in Korea, and a number of samples tested positive (27.1%) for the targeted drugs. This analytical method is suitable for reliable detection of veterinary drug residues in Fishery Products.

  • Occurrence of veterinary drug residues in farmed Fishery Products in South Korea
    Food Control, 2018
    Co-Authors: Hui-seung Kang, Soo-bin Lee, Dasom Shin, Jiyoon Jeong, Jin-hwan Hong, Gyu-seek Rhee
    Abstract:

    Abstract Residues of veterinary drugs were investigated in fish samples from domestic farms in South Korea to highlight the changing trends in drug usage during aquatic food production. Samples (n = 958) were collected from 32 cities and 11 provinces. In total, 41 veterinary drugs were analyzed using an LC-MS/MS. The total detection rate of veterinary drugs in fish samples was 22.7% (n = 217). Enrofloxacin and oxytetracycline were mostly detected in Fishery Products. Moreover, 12 samples (1.3%) exceeded the maximum residue limit set by Korea. The detection rate for veterinary drug residues varied with fish species and water type. Additionally, our findings show that of the two or more residues in 87 samples, enrofloxacin was often detected in combination with ciprofloxacin, and other compound. Our results of this study suggested the need for an appropriate withdrawal period of Fishery Products are required to guarantee safe residue levels.

Paul W Elsinghors - One of the best experts on this subject based on the ideXlab platform.

Paul W Elsinghorst - One of the best experts on this subject based on the ideXlab platform.

  • determination of the synthetic antioxidant ethoxyquin and its metabolites in fish and Fishery Products using liquid chromatography fluorescence detection and stable isotope dilution analysis liquid chromatography tandem mass spectrometry
    Journal of Agricultural and Food Chemistry, 2019
    Co-Authors: Andreas Kranawetvogl, Paul W Elsinghorst
    Abstract:

    The use of the synthetic antioxidant ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) as a flame retardant in fish meal transported by sea is required by international authorities to prevent self-ignition. Because of extensive carry-over within the food chain, selective and sensitive analytical methods are required for investigations on human exposure and the safety of EQ and its metabolites. Therefore, a simple, fast, and rugged liquid-chromatography (LC) method was developed for the detection of EQ and its metabolites in fish and Fishery Products after liquid-liquid extraction using QuEChERS. For screening purposes, a fluorescence detector was used (LC-FLD) with the EQ-analogue methoxyquin serving as an internal standard. For stable-isotope dilution analysis by liquid chromatography-tandem mass spectrometry (SIDA-LC-MS/MS), deuterated analogues of EQ and its metabolites were synthesized for the first time and allowed for sensitive quantification and thus confirmation of screening results. Both methods were validated and successfully applied to commercially available fish samples.

Graham J Pierce - One of the best experts on this subject based on the ideXlab platform.

  • human health legislative and socioeconomic issues caused by the fish borne zoonotic parasite anisakis challenges in risk assessment
    Trends in Food Science and Technology, 2019
    Co-Authors: Miguel Bao, Santiago Pascual, Graham J Pierce, Norval J C Strachan, Miguel Gonzalezmunoz, Arne Levsen
    Abstract:

    Abstract Background Nematodes of the genus Anisakis parasitize many commercial fish species and are responsible for a fish-borne zoonosis (anisakiasis) and allergic reactions. Anisakis can also cause consumer distrust in Fishery Products and economic losses to the fish industry. Scope and approach We review current socioeconomic, legislative, risk management and human health problems caused by the occurrence of Anisakis in Fishery Products and discuss possible strategies to mitigate them. Key findings and conclusions Visual inspection (and candling) of Fishery Products as required by EU legislation is not efficient for parasite detection. Consequently, visible (and non-visible) Anisakis reach the market and may be detected (and eaten) by consumers. Marine fish appears to be the only industrial food product that is at high risk of containing parasites when placed on the market. Anisakiasis and allergy to Anisakis are hidden, underestimated emerging zoonoses worldwide. There is a need to better understand the impact of these zoonoses on individual health and particularly exposed human populations, and to assess the risk posed by Anisakis allergens in Fishery Products. Quantitative risk assessment (QRA) is identified as an appropriate methodology as it estimates the risk from fishing ground to human disease. Improvements in parasite control legislation and procedures (e.g. establishment of research-based and standardized parasite detection methodologies, appropriate sampling strategies, development of non-destructive methods for detection and removal of nematodes from fish Products), suitable for use by seafood businesses, are recommended to improve protection of consumers and to protect the industry by minimizing Anisakis-associated economic losses. QRA may help to provide the scientific basis for improved food safety legislation and strategies to reduce the risk of anisakiasis/allergy in humans.