The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform
Herman A. Cohen - One of the best experts on this subject based on the ideXlab platform.
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Fixed Drug Eruption of the penis due to hydroxyzine hydrochloride
Annals of Pharmacotherapy, 1997Co-Authors: Herman A. Cohen, Asher Barzilai, Andre Matalon, Liora Harel, Samuel GrossAbstract:ObjectiveTo report four cases of Fixed Drug Eruption induced by hydroxyzine hydrochloride (Otarex, Teva, Israel).Case SummaryFour children with restlessness who were treated with hydroxyzine hydrochloride developed Fixed Drug Eruption of the penis. Drug discontinuation was followed by complete resolution of the skin Eruption. Rechallenge resulted in the same Drug rash. Macrophage migration inhibiting factor (MIF) assay with hydroxyzine hydrochloride was positive.DiscussionThe pathogenesis of Fixed Drug Eruption and the role of macrophage MTF assay in diagnosis is discussed.ConclusionsA Fixed Drug Eruption induced by hydroxyzine hydrochloride is possible, but is a rare phenomenon.
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Fixed Drug Eruption of the scrotum due to hydroxyzine hydrochloride (Atarax)
Cutis, 1996Co-Authors: Herman A. Cohen, Cohen Z, Moshe FrydmanAbstract:Fixed Drug Eruption describes a sharply localized dermatitis that characteristically recurs at the same site each time the offending Drug is administered. Several Drugs have been reported to cause this Eruption, such as phenolphthalein, barbiturates, penicillin, and others. In this report, two children with Fixed Drug Eruption of the scrotum due to hydroxyzine hydrochloride (Atarax) are described. To the best of our knowledge, no such cases have been reported previously in children.
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Fixed Drug Eruption of the Scrotum Due to Methylphenidate
Annals of Pharmacotherapy, 1992Co-Authors: Herman A. Cohen, Arie Ashkenazi, Shmuel Gross, Moshe Nussinovitch, Moshe FrydmanAbstract:OBJECTIVE:To report two cases of Fixed Drug Eruption induced by methylphenidate.CASE SUMMARY:Two children with attention deficit disorder treated with methylphenidate as a simple Drug developed Fixed Drug Eruption of the scrotum. Drug discontinuation was followed by a complete resolution of the skin Eruption. Rechallenge resulted in the same Drug rash. Macrophage migration-inhibiting factor (MIF) assay with methylphenidate was positive.DISCUSSION:The pathogenesis of Fixed Drug Eruption and the role of MIF assay in the diagnosis of adverse Drug reaction is discussed.CONCLUSIONS:Fixed Drug rash induced by methylphenidate is a possible but rare phenomenon.
R. Marks - One of the best experts on this subject based on the ideXlab platform.
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Fixed Drug Eruption to mefenamic acid: a report of three cases.
The British journal of dermatology, 1992Co-Authors: C.c. Long, Andrew Yule Finlay, R. MarksAbstract:Summary Mefenamic acid (Ponstan®) is widely used in the treatment of dysmenorrhoea, menorrhagia, and musculoskeletal pain. Although only 17 cases of Fixed Drug Eruption provoked by mefenamic acid have been reported in the world literature, in a 7-day period a further three patients with Fixed Drug Eruption due to mefenamic acid presented to the dermatology out-patient clinic of the University Hospital of Wales, Cardiff. The lesions of all the patients became inflamed within a few hours of taking the Drug, but two of the three patients failed to appreciate the association. There have been no further episodes of inflammation since the patients avoided mefenamic acid.
R Garcia - One of the best experts on this subject based on the ideXlab platform.
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Nonpigmented Fixed Drug Eruption caused by paracetamol.
Journal of Investigational Allergology and Clinical Immunology, 1999Co-Authors: P. A. Galindo, Cesar Encinas, J. Borja, E Gomez, R GarciaAbstract:: Fixed Drug Eruption from paracetamol is not rare but no cases of nonpigmented Fixed Drug Eruption caused by paracetamol have been previously described. We present the case of a woman who developed a nonpigmented Fixed Drug Eruption following administration of paracetamol. Patch tests performed on affected and unaffected skin with paracetamol were negative. The diagnosis was made by a double-blind oral challenge with paracetamol. The patient tolerated aspirin.
Azucena Prieto - One of the best experts on this subject based on the ideXlab platform.
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Nonpigmenting Fixed Drug Eruption due to Pseudoephedrine
Annals of Allergy Asthma & Immunology, 1998Co-Authors: Carmen Vidal, Celsa Pérez-carral, Margarita Armisén, Azucena PrietoAbstract:Background The nonpigmenting Fixed Drug Eruption is a distictive Drug reaction characterized by large, tender and symmetric erythematous plaques that diappear with no residual pigmentation. Methods A case of a non-pigmenting Fixed Drug Eruption due to pseudoephedrine is reported. Results The reappearance of typical lesions at the same sites after oral challenge with 60 mg pseudoephedrine together with the absence of pigmentation confirm the diagnosis. Conclusion A new case of proven nonpigmenting Fixed Drug Eruption to pseudoephedrine is described.
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Nonpigmenting Fixed Drug Eruption due to Pseudoephedrine
Annals of allergy asthma & immunology : official publication of the American College of Allergy Asthma & Immunology, 1998Co-Authors: Carmen Vidal, Celsa Pérez-carral, Margarita Armisén, Azucena PrietoAbstract:The nonpigmenting Fixed Drug Eruption is a distinctive Drug reaction characterized by large, tender and symmetric erythematous plaques that disappear with no residual pigmentation. A case of a non-pigmenting Fixed Drug Eruption due to pseudoephedrine is reported. The reappearance of typical lesions at the same sites after oral challenge with 60 mg pseudoephedrine together with the absence of pigmentation confirm the diagnosis. A new case of proven nonpigmenting Fixed Drug Eruption to pseudoephedrine is described.
Moshe Frydman - One of the best experts on this subject based on the ideXlab platform.
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Fixed Drug Eruption of the scrotum due to hydroxyzine hydrochloride (Atarax)
Cutis, 1996Co-Authors: Herman A. Cohen, Cohen Z, Moshe FrydmanAbstract:Fixed Drug Eruption describes a sharply localized dermatitis that characteristically recurs at the same site each time the offending Drug is administered. Several Drugs have been reported to cause this Eruption, such as phenolphthalein, barbiturates, penicillin, and others. In this report, two children with Fixed Drug Eruption of the scrotum due to hydroxyzine hydrochloride (Atarax) are described. To the best of our knowledge, no such cases have been reported previously in children.
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Fixed Drug Eruption of the Scrotum Due to Methylphenidate
Annals of Pharmacotherapy, 1992Co-Authors: Herman A. Cohen, Arie Ashkenazi, Shmuel Gross, Moshe Nussinovitch, Moshe FrydmanAbstract:OBJECTIVE:To report two cases of Fixed Drug Eruption induced by methylphenidate.CASE SUMMARY:Two children with attention deficit disorder treated with methylphenidate as a simple Drug developed Fixed Drug Eruption of the scrotum. Drug discontinuation was followed by a complete resolution of the skin Eruption. Rechallenge resulted in the same Drug rash. Macrophage migration-inhibiting factor (MIF) assay with methylphenidate was positive.DISCUSSION:The pathogenesis of Fixed Drug Eruption and the role of MIF assay in the diagnosis of adverse Drug reaction is discussed.CONCLUSIONS:Fixed Drug rash induced by methylphenidate is a possible but rare phenomenon.