The Experts below are selected from a list of 240 Experts worldwide ranked by ideXlab platform
G Venkateswaran - One of the best experts on this subject based on the ideXlab platform.
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direct determination of uranium in seawater by laser Fluorimetry
Talanta, 2008Co-Authors: Sanjukta A Kumar, Niyoti Shenoy, Shailaja P Pandey, Suvarna Sounderajan, G VenkateswaranAbstract:A method for estimation of uranium in seawater by using steady state laser flourimetry is described. Uranium present in seawater, in concentration of approximately 3 ng ml(-1) was estimated without prior separation of matrix. Quenching effect of major ions (Cl(-), Na(+), SO(4)(-), Mg(+), Ca(+), K(+), HCO(3)(-), Br(-)) present in seawater on fluorescence intensity of uranium was studied. The concentration of phosphoric acid required for maximum enhancement of fluorescence intensity was optimized and was found to be 5%. Similarly the volume of concentrated nitric acid required to eliminate the quenching effect of chloride and bromide completely from 5 ml of seawater were optimized and was found to be 3 ml. A simple equation was derived using steady state fluorescence correction method and was used for calculation of uranium concentration in seawater samples. The method has a precesion of 1% (1s, n=3). The values obtained from laser Fluorimetry were validated by analyzing the same samples by linear sweep adsorptive stripping voltametry (LSASV) of the uranium-chloranilic acid (2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) complex. Both the values are well in agreement.
Sanjukta A Kumar - One of the best experts on this subject based on the ideXlab platform.
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direct determination of uranium in seawater by laser Fluorimetry
Talanta, 2008Co-Authors: Sanjukta A Kumar, Niyoti Shenoy, Shailaja P Pandey, Suvarna Sounderajan, G VenkateswaranAbstract:A method for estimation of uranium in seawater by using steady state laser flourimetry is described. Uranium present in seawater, in concentration of approximately 3 ng ml(-1) was estimated without prior separation of matrix. Quenching effect of major ions (Cl(-), Na(+), SO(4)(-), Mg(+), Ca(+), K(+), HCO(3)(-), Br(-)) present in seawater on fluorescence intensity of uranium was studied. The concentration of phosphoric acid required for maximum enhancement of fluorescence intensity was optimized and was found to be 5%. Similarly the volume of concentrated nitric acid required to eliminate the quenching effect of chloride and bromide completely from 5 ml of seawater were optimized and was found to be 3 ml. A simple equation was derived using steady state fluorescence correction method and was used for calculation of uranium concentration in seawater samples. The method has a precesion of 1% (1s, n=3). The values obtained from laser Fluorimetry were validated by analyzing the same samples by linear sweep adsorptive stripping voltametry (LSASV) of the uranium-chloranilic acid (2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) complex. Both the values are well in agreement.
Gerwin J. Puppels - One of the best experts on this subject based on the ideXlab platform.
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Pretransplantation assessment of renal viability with NADH Fluorimetry.
Kidney international, 2000Co-Authors: J. M. C. C. Coremans, Matthijs Van Aken, Daniëlle C.w.h. Naus, Marie-louise F Van Velthuysen, Hajo A. Bruining, Gerwin J. PuppelsAbstract:Pretransplantation assessment of renal viability with NADH Fluorimetry. Background A pathophysiologic feature possibly involved in ischemic injury in transplant kidneys is mitochondrial dysfunction caused by disintegration of oxidative metabolic pathways. Because the ability to synthesize ATP by respiratory activity determines the organ's capacity to recover from ischemic injury, an assessment of respiratory activity may provide information related to graft viability. Methods NADH Fluorimetry can be used to monitor kidney cortex metabolism noninvasively. During perfusion with (an)-aerobic perfusate, NADH fluorescence images were recorded. We evaluated the NADH oxidation kinetics of 20 rat kidneys, which were divided over four experimental groups. For six minimally damaged kidneys and six kidneys that had been stored for one hour at 37°C, perfusion was followed by transplantation. We related the kinetic parameters of these kidneys with their post-transplantation function and histology. The transplant function was monitored by serum creatinine and urea levels. Results Storage of transplant kidneys for one hour at 37°C significantly reduced the post-transplantation function. Isolated perfusion of grafts, however, was not detrimental for renal function. The rate of NADH oxidation decreased with decreasing graft quality, and a good correlation between NADH oxidation kinetics and post-transplantation function was found. Conclusions A reduction of NADH oxidation rates as a consequence of warm ischemia supports the view that mitochondrial respiratory activity is impaired by ischemic injury. The correlation between NADH oxidation kinetics in perfused grafts and their post-transplantation function indicates that NADH Fluorimetry may be useful in predicting the viability of preserved grafts prior to transplantation.
Davide Cerioli - One of the best experts on this subject based on the ideXlab platform.
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Quantification of circulating cell-free DNA by Fluorimetry (Qubit) and spectrophotometry (NanoDrop) in patients with malignant melanoma and prostate cancer
Annals of Oncology, 2016Co-Authors: Giovanni Ponti, Monia Maccaferri, Roberta Depenni, Mauro Mandrioli, Giovanni Pellacani, Marco Manfredini, T Ozben, Cristel Ruini, Elena Iattoni, Davide CerioliAbstract:Quantification of circulating cell-free DNA by Fluorimetry (Qubit) and spectrophotometry (NanoDrop) in patients with malignant melanoma and prostate cance
Eleftherios P Diamandis - One of the best experts on this subject based on the ideXlab platform.
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Time-resolved fluorometry in nucleic acid hybridization and Western blotting techniques
Electrophoresis, 1993Co-Authors: Eleftherios P DiamandisAbstract:Time-resolved fluorometry is now used extensively for immunological assays and to a lesser extent in other research areas. In this review I describe applications of time-resolved fluorometry in nucleic acid hybridization and in blotting techniques, including Southern and Western blotting. Clearly, timeresolved fluorometry has potential for playing a major role in techniques other than immunological assays.